Imaging synaptic density in the living human brain

Synthesis and Preclinical Evaluation of 11C-UCB-J as a PET Tracer for Imaging the Synaptic Vesicle Glycoprotein 2A in the Brain

(2016) N. B. Nabulsi et al.   JOURNAL OF NUCLEAR MEDICINE

Schizophrenia risk from complex variation of complement component 4

(2016) Aswin Sekar et al.   NATURE

[11C]UCB-A, a novel PET tracer for synaptic vesicle protein 2A

(2016) Sergio Estrada et al.   NUCLEAR MEDICINE AND BIOLOGY

Fyn inhibition rescues established memory and synapse loss in Alzheimer mice

(2015) Adam C. Kaufman et al.   ANNALS OF NEUROLOGY

Biodistribution and Radiation Dosimetry for the Novel SV2A Radiotracer [18F]UCB-H: First-in-Human Study

(2015) F. Bretin et al.   MOLECULAR IMAGING AND BIOLOGY

Pathogenesis of synaptic degeneration in Alzheimer's disease and Lewy body disease

(2014) Cassia R. Overk et al.   BIOCHEMICAL PHARMACOLOGY

Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old

(2014) John L. Robinson et al.   BRAIN

Discovery of Heterocyclic Nonacetamide Synaptic Vesicle Protein 2A (SV2A) Ligands with Single-Digit Nanomolar Potency: Opening Avenues towards the First SV2A Positron Emission Tomography (PET) Ligands

(2014) Joël Mercier et al.   ChemMedChem

Parametric Imaging and Test-Retest Variability of 11C-(+)-PHNO Binding to D2/D3 Dopamine Receptors in Humans on the High-Resolution Research Tomograph PET Scanner

(2014) J.-D. Gallezot et al.   JOURNAL OF NUCLEAR MEDICINE

Evaluation of 18F-UCB-H as a Novel PET Tracer for Synaptic Vesicle Protein 2A in the Brain

(2014) G. I. Warnock et al.   JOURNAL OF NUCLEAR MEDICINE

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

(2014) Guomei Tang et al.   NEURON

Test–retest reliability of [11C]AZ10419369 binding to 5-HT1B receptors in human brain

(2013) Magdalena Nord et al.   EUROPEAN JOURNAL OF NUCLEAR MEDICINE AND MOLECULAR IMAGING

Expression pattern of synaptic vesicle protein 2 (SV2) isoforms in patients with temporal lobe epilepsy and hippocampal sclerosis

(2013) J. Crèvecœur et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

List-mode reconstruction for the Biograph mCT with physics modeling and event-by-event motion correction

(2013) Xiao Jin et al.   PHYSICS IN MEDICINE AND BIOLOGY

The Development, Past Achievements, and Future Directions of Brain PET

(2012) Terry Jones et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Decreased expression of synapse-related genes and loss of synapses in major depressive disorder

(2012) Hyo Jung Kang et al.   NATURE MEDICINE

Optimization of PET–MR registrations for nonhuman primates using mutual information measures: A Multi-Transform Method (MTM)

(2012) Christine M. Sandiego et al.   NEUROIMAGE

Binding characteristics of brivaracetam, a selective, high affinity SV2A ligand in rat, mouse and human brain: Relationship to anti-convulsant properties

(2011) Michel Gillard et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protein Quantification at the Single Vesicle Level Reveals That a Subset of Synaptic Vesicle Proteins Are Trafficked with High Precision

(2011) S. A. Mutch et al.   JOURNAL OF NEUROSCIENCE

Equal numbers of neuronal and nonneuronal cells make the human brain an isometrically scaled-up primate brain

(2009) Frederico A.C. Azevedo et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Down-regulation Synaptic Vesicle Protein 2A in the Anterior Temporal Neocortex of Patients with Intractable Epilepsy

(2009) Guibo Feng et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Decreased expression of synaptic vesicle protein 2A, the binding site for levetiracetam, during epileptogenesis and chronic epilepsy

(2008) Erwin A. van Vliet et al.   EPILEPSIA

Pathology and pathophysiology of the amygdala in epileptogenesis and epilepsy

(2008) Vassiliki Aroniadou-Anderjaska et al.   EPILEPSY RESEARCH

Gender differences in human cortical synaptic density

(2008) L. Alonso-Nanclares et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA