DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes
Published 2015 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes
Authors
Keywords
-
Journal
NUCLEIC ACIDS RESEARCH
Volume 43, Issue 2, Pages 943-959
Publisher
Oxford University Press (OUP)
Online
2015-01-01
DOI
10.1093/nar/gku1356
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The KATP Channel Activator Diazoxide Ameliorates Amyloid-β and Tau Pathologies and Improves Memory in the 3xTgAD Mouse Model of Alzheimer's Disease
- (2017) Dong Liu et al. JOURNAL OF ALZHEIMERS DISEASE
- Cockayne Syndrome B protein antagonizes OGG1 in modulating CAG repeat length in vivo
- (2016) Irina V. Kovtun et al. Aging-US
- Targeting neurogenesis ameliorates danger assessment in a mouse model of Alzheimer's disease
- (2014) Adi Shruster et al. BEHAVIOURAL BRAIN RESEARCH
- Dual roles for autophagy: Degradation and secretion of Alzheimer's disease Aβ peptide
- (2014) Per Nilsson et al. BIOESSAYS
- Defective Mitophagy in XPA via PARP-1 Hyperactivation and NAD+/SIRT1 Reduction
- (2014) Evandro Fei Fang et al. CELL
- NAD attenuates oxidative DNA damages induced by amyloid beta-peptide in primary rat cortical neurons
- (2014) M.-F. Wu et al. FREE RADICAL RESEARCH
- Base excision DNA repair levels in mitochondrial lysates of Alzheimer's disease
- (2014) Chandrika Canugovi et al. NEUROBIOLOGY OF AGING
- DNA Damage and Its Links to Neurodegeneration
- (2014) Ram Madabhushi et al. NEURON
- Alzheimer’s disease drug-development pipeline: few candidates, frequent failures
- (2014) Jeffrey L Cummings et al. Alzheimers Research & Therapy
- Integrated Systems Approach Identifies Genetic Nodes and Networks in Late-Onset Alzheimer’s Disease
- (2013) Bin Zhang et al. CELL
- Altered Expression of Diabetes-Related Genes in Alzheimer's Disease Brains: The Hisayama Study
- (2013) Masaaki Hokama et al. CEREBRAL CORTEX
- DNA-repair in mild cognitive impairment and Alzheimer's disease
- (2013) Nina Bucholtz et al. DNA REPAIR
- Lymphocytes of Patients with Alzheimer’s Disease Display Different DNA Damage Repair Kinetics and Expression Profiles of DNA Repair and Stress Response Genes
- (2013) Giovana Leandro et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nucleic acid oxidation: an early feature of Alzheimer's disease
- (2013) Melissa A. Bradley-Whitman et al. JOURNAL OF NEUROCHEMISTRY
- Base excision repair in the mammalian brain: Implication for age related neurodegeneration
- (2013) Peter Sykora et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Transient OGG1, APE1, PARP1 and Polβ expression in an Alzheimer's disease mouse model
- (2013) Meryl S. Lillenes et al. MECHANISMS OF AGEING AND DEVELOPMENT
- High-throughput comet assay using 96 minigels
- (2013) Kristine B. Gutzkow et al. MUTAGENESIS
- The role of autophagy in neurodegenerative disease
- (2013) Ralph A Nixon NATURE MEDICINE
- Physiologic brain activity causes DNA double-strand breaks in neurons, with exacerbation by amyloid-β
- (2013) Elsa Suberbielle et al. NATURE NEUROSCIENCE
- Mitochondrial DNA damage in a mouse model of Alzheimer's disease decreases amyloid beta plaque formation
- (2013) Milena Pinto et al. NEUROBIOLOGY OF AGING
- Modulation of DNA base excision repair during neuronal differentiation
- (2013) Peter Sykora et al. NEUROBIOLOGY OF AGING
- BDNF and Exercise Enhance Neuronal DNA Repair by Stimulating CREB-Mediated Production of Apurinic/Apyrimidinic Endonuclease 1
- (2013) Jenq-Lin Yang et al. NEUROMOLECULAR MEDICINE
- Bridging animal and human models of exercise-induced brain plasticity
- (2013) Michelle W. Voss et al. TRENDS IN COGNITIVE SCIENCES
- Aβ Secretion and Plaque Formation Depend on Autophagy
- (2013) Per Nilsson et al. Cell Reports
- Sporadic Alzheimer disease fibroblasts display an oxidative stress phenotype
- (2012) Mahesh Ramamoorthy et al. FREE RADICAL BIOLOGY AND MEDICINE
- Alzheimer’s Disease-Associated Neurotoxic Peptide Amyloid-Β Impairs Base Excision Repair in Human Neuroblastoma Cells
- (2012) Anne Forestier et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Nicotinamide forestalls pathology and cognitive decline in Alzheimer mice: evidence for improved neuronal bioenergetics and autophagy procession
- (2012) Dong Liu et al. NEUROBIOLOGY OF AGING
- Endonuclease VIII-like 1 (NEIL1) promotes short-term spatial memory retention and protects from ischemic stroke-induced brain dysfunction and death in mice
- (2012) C. Canugovi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The AAA+ ATPase Thorase Regulates AMPA Receptor-Dependent Synaptic Plasticity and Behavior
- (2011) Jianmin Zhang et al. CELL
- Asymptomatic Alzheimers Disease: A Prodrome or a State of Resilience?
- (2011) I. Driscoll et al. Current Alzheimer Research
- Accelerated Age-Related Cognitive Decline and Neurodegeneration, Caused by Deficient DNA Repair
- (2011) N. Z. Borgesius et al. JOURNAL OF NEUROSCIENCE
- Oxidatively modified nucleic acids in preclinical Alzheimer's disease (PCAD) brain
- (2011) Mark A. Lovell et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Down syndrome as a model of DNA polymerase beta haploinsufficiency and accelerated aging
- (2011) David Patterson et al. MECHANISMS OF AGEING AND DEVELOPMENT
- DNA damage response signaling in lung adenocarcinoma A549 cells following gamma and carbon beam irradiation
- (2011) Somnath Ghosh et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Amitriptyline-Mediated Cognitive Enhancement in Aged 3×Tg Alzheimer's Disease Mice Is Associated with Neurogenesis and Neurotrophic Activity
- (2011) Wayne Chadwick et al. PLoS One
- 2-Deoxy-D-Glucose Treatment Induces Ketogenesis, Sustains Mitochondrial Function, and Reduces Pathology in Female Mouse Model of Alzheimer's Disease
- (2011) Jia Yao et al. PLoS One
- RNA Oxidation Adducts 8-OHG and 8-OHA Change with Aβ42 Levels in Late-Stage Alzheimer's Disease
- (2011) Adam M. Weidner et al. PLoS One
- Endonuclease VIII-like 3 (Neil3) DNA glycosylase promotes neurogenesis induced by hypoxia-ischemia
- (2011) Y. Sejersted et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Nuclear entry of active caspase-3 is facilitated by its p3-recognition-based specific cleavage activity
- (2010) Min Luo et al. CELL RESEARCH
- The plasma membrane redox system is impaired by amyloid β-peptide and in the hippocampus and cerebral cortex of 3xTgAD mice
- (2010) Dong-Hoon Hyun et al. EXPERIMENTAL NEUROLOGY
- Increased levels of 4-hydroxynonenal and acrolein in the brain in preclinical Alzheimer disease
- (2010) M.A. Bradley et al. FREE RADICAL BIOLOGY AND MEDICINE
- Evidence that OGG1 Glycosylase Protects Neurons against Oxidative DNA Damage and Cell Death under Ischemic Conditions
- (2010) Dong Liu et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Variation in base excision repair capacity
- (2010) David M. Wilson et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease
- (2010) Marcello D'Amelio et al. NATURE NEUROSCIENCE
- Elevated 4-hydroxyhexenal in Alzheimer's disease (AD) progression
- (2010) Melissa A. Bradley et al. NEUROBIOLOGY OF AGING
- Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain
- (2010) Troy T. Rohn et al. NEUROBIOLOGY OF DISEASE
- Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
- (2010) M Djavaheri-Mergny et al. ONCOGENE
- Proteomic identification of HNE-bound proteins in early Alzheimer disease: Insights into the role of lipid peroxidation in the progression of AD
- (2009) Tanea T. Reed et al. BRAIN RESEARCH
- Direct and indirect roles of RECQL4 in modulating base excision repair capacity
- (2009) Shepherd H. Schurman et al. HUMAN MOLECULAR GENETICS
- DNA Damage, Aging, and Cancer
- (2009) Jan H.J. Hoeijmakers NEW ENGLAND JOURNAL OF MEDICINE
- Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease
- (2009) J. Yao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Females exhibit more extensive amyloid, but not tau, pathology in an Alzheimer transgenic model
- (2008) Chiho Hirata-Fukae et al. BRAIN RESEARCH
- Mitochondrial base excision repair of uracil and AP sites takes place by single-nucleotide insertion and long-patch DNA synthesis
- (2008) Mansour Akbari et al. DNA REPAIR
- Altered 8-oxoguanine glycosylase in mild cognitive impairment and late-stage Alzheimer's disease brain
- (2008) Changxing Shao et al. FREE RADICAL BIOLOGY AND MEDICINE
- DNA polymerase β-catalyzed-PCNA independent long patch base excision repair synthesis: a mechanism for repair of oxidatively damaged DNA ends in post-mitotic brain
- (2008) Wei Wei et al. JOURNAL OF NEUROCHEMISTRY
- Mitochondria in Neuroplasticity and Neurological Disorders
- (2008) Mark P. Mattson et al. NEURON
- Impaired Adult Neurogenesis in the Dentate Gyrus of a Triple Transgenic Mouse Model of Alzheimer's Disease
- (2008) José J. Rodríguez et al. PLoS One
- The γ-H2A.X: Is it just a surrogate marker of double-strand breaks or much more?
- (2007) Ismail Hassan Ismail et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Oxidatively modified RNA in mild cognitive impairment
- (2007) Mark A. Lovell et al. NEUROBIOLOGY OF DISEASE
- Modulation of DNA polymerase beta-dependent base excision repair in cultured human cells after low dose exposure to arsenite
- (2007) Peter Sykora et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
Find the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
SearchAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now