ALS-associated mutation FUS-R521C causes DNA damage and RNA splicing defects

Interaction of FUS and HDAC1 regulates DNA damage response and repair in neurons

(2013) Wen-Yuan Wang et al.   NATURE NEUROSCIENCE

SIRT1 collaborates with ATM and HDAC1 to maintain genomic stability in neurons

(2013) Matthew M Dobbin et al.   NATURE NEUROSCIENCE

Overexpression of human wild-type FUS causes progressive motor neuron degeneration in an age- and dose-dependent fashion

(2012) Jacqueline C. Mitchell et al.   ACTA NEUROPATHOLOGICA

A qPCR-based assay to quantify oxidized guanine and other FPG-sensitive base lesions within telomeric DNA

(2012) Nathan O’Callaghan et al.   BIOTECHNIQUES

Cell-free Formation of RNA Granules: Low Complexity Sequence Domains Form Dynamic Fibers within Hydrogels

(2012) Masato Kato et al.   CELL

Assembly of synaptic laminae by axon guidance molecules

(2012) Estuardo Robles et al.   CURRENT OPINION IN NEUROBIOLOGY

fus/TLS orchestrates splicing of developmental regulators during gastrulation

(2012) D. S. Dichmann et al.   GENES & DEVELOPMENT

An epigenetic blockade of cognitive functions in the neurodegenerating brain

(2012) Johannes Gräff et al.   NATURE

Dendritically targeted Bdnf mRNA is essential for energy balance and response to leptin

(2012) Guey-Ying Liao et al.   NATURE MEDICINE

Widespread binding of FUS along nascent RNA regulates alternative splicing in the brain

(2012) Boris Rogelj et al.   Scientific Reports

Assembly of Lamina-Specific Neuronal Connections by Slit Bound to Type IV Collagen

(2011) Tong Xiao et al.   CELL

RNA targets of wild-type and mutant FET family proteins

(2011) Jessica I Hoell et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A yeast functional screen predicts new candidate ALS disease genes

(2011) J. Couthouis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Determinants and Genetic Modifiers of Aggregation and Toxicity for the ALS Disease Protein FUS/TLS

(2011) Zhihui Sun et al.   PLOS BIOLOGY

FUS Transgenic Rats Develop the Phenotypes of Amyotrophic Lateral Sclerosis and Frontotemporal Lobar Degeneration

(2011) Cao Huang et al.   PLoS Genetics

Distinct pathological subtypes of FTLD-FUS

(2010) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

Extensive FUS-Immunoreactive Pathology in Juvenile Amyotrophic Lateral Sclerosis with Basophilic Inclusions

(2010) Eric J. Huang et al.   BRAIN PATHOLOGY

Blocking the mitochondrial apoptotic pathway preserves motor neuron viability and function in a mouse model of amyotrophic lateral sclerosis

(2010) Nichole A. Reyes et al.   JOURNAL OF CLINICAL INVESTIGATION

Global Deprivation of Brain-Derived Neurotrophic Factor in the CNS Reveals an Area-Specific Requirement for Dendritic Growth

(2010) S. Rauskolb et al.   JOURNAL OF NEUROSCIENCE

Detection of splice junctions from paired-end RNA-seq data by SpliceMap

(2010) K. F. Au et al.   NUCLEIC ACIDS RESEARCH

Differential expression analysis for sequence count data

(2010) Simon Anders et al.   GENOME BIOLOGY

Many Paths to Synaptic Specificity

(2009) Joshua R. Sanes et al.   Annual Review of Cell and Developmental Biology

Stringent Specificity in the Construction of a GABAergic Presynaptic Inhibitory Circuit

(2009) J. Nicholas Betley et al.   CELL

Pre-mRNA Processing Reaches Back toTranscription and Ahead to Translation

(2009) Melissa J. Moore et al.   CELL

DNA Damage Regulates Alternative Splicing through Inhibition of RNA Polymerase II Elongation

(2009) Manuel J. Muñoz et al.   CELL

mRNA Localization: Gene Expression in the Spatial Dimension

(2009) Kelsey C. Martin et al.   CELL

RNA and Disease

(2009) Thomas A. Cooper et al.   CELL

The Spliceosome: Design Principles of a Dynamic RNP Machine

(2009) Markus C. Wahl et al.   CELL

Sporadic ALS has compartment-specific aberrant exon splicing and altered cell–matrix adhesion biology

(2009) Stuart J. Rabin et al.   HUMAN MOLECULAR GENETICS

The DNA-damage response in human biology and disease

(2009) Stephen P. Jackson et al.   NATURE

Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources

(2009) Da Wei Huang et al.   Nature Protocols

Disorders of nucleotide excision repair: the genetic and molecular basis of heterogeneity

(2009) James E. Cleaver et al.   NATURE REVIEWS GENETICS

Mutations in FUS, an RNA Processing Protein, Cause Familial Amyotrophic Lateral Sclerosis Type 6

(2009) C. Vance et al.   SCIENCE

Mutations in the FUS/TLS Gene on Chromosome 16 Cause Familial Amyotrophic Lateral Sclerosis

(2009) T. J. Kwiatkowski et al.   SCIENCE

Distinct Role of Long 3′ UTR BDNF mRNA in Spine Morphology and Synaptic Plasticity in Hippocampal Neurons

(2008) Juan Ji An et al.   CELL

Dopamine D1 Receptor-induced Signaling through TrkB Receptors in Striatal Neurons

(2008) Yuriko Iwakura et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Biosynthesis and processing of endogenous BDNF: CNS neurons store and secrete BDNF, not pro-BDNF

(2008) Tomoya Matsumoto et al.   NATURE NEUROSCIENCE

Deregulation of HDAC1 by p25/Cdk5 in Neurotoxicity

(2008) Dohoon Kim et al.   NEURON

Evolution of the Aging Brain Transcriptome and Synaptic Regulation

(2008) Patrick M. Loerch et al.   PLoS One