Mutant Huntingtin promotes autonomous microglia activation via myeloid lineage-determining factors

Impaired basal and running-induced hippocampal neurogenesis coincides with reduced Akt signaling in adult R6/1 HD mice

(2013) Mark I. Ransome et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

(2013) Katrin Kierdorf et al.   NATURE NEUROSCIENCE

The genetics and neuropathology of Alzheimer’s disease

(2012) Gerard D. Schellenberg et al.   ACTA NEUROPATHOLOGICA

Characterization of genome-wide enhancer-promoter interactions reveals co-expression of interacting genes and modes of higher order chromatin organization

(2012) Iouri Chepelev et al.   CELL RESEARCH

Regulation of C/EBPβ and resulting functions in cells of the monocytic lineage

(2012) René Huber et al.   CELLULAR SIGNALLING

Comprehensive Behavioral and Molecular Characterization of a New Knock-In Mouse Model of Huntington’s Disease: zQ175

(2012) Liliana B. Menalled et al.   PLoS One

Characterization of Neurophysiological and Behavioral Changes, MRI Brain Volumetry and 1H MRS in zQ175 Knock-In Mouse Model of Huntington's Disease

(2012) Taneli Heikkinen et al.   PLoS One

A Lineage of Myeloid Cells Independent of Myb and Hematopoietic Stem Cells

(2012) C. Schulz et al.   SCIENCE

The CCAAT/enhancer (C/EBP) family of basic-leucine zipper (bZIP) transcription factors is a multifaceted highly-regulated system for gene regulation

(2011) Junichi Tsukada et al.   CYTOKINE

Activated microglia proliferate at neurites of mutant huntingtin-expressing neurons

(2011) Andrew D. Kraft et al.   NEUROBIOLOGY OF AGING

Age-dependent neurovascular abnormalities and altered microglial morphology in the YAC128 mouse model of Huntington disease

(2011) Sonia Franciosi et al.   NEUROBIOLOGY OF DISEASE

Impaired adult olfactory bulb neurogenesis in the R6/2 mouse model of Huntington's disease

(2010) Zacharias Kohl et al.   BMC NEUROSCIENCE

Inflammation 2010: New Adventures of an Old Flame

(2010) Ruslan Medzhitov   CELL

Microglial activation in regions related to cognitive function predicts disease onset in Huntington's disease: A multimodal imaging study

(2010) Marios Politis et al.   HUMAN BRAIN MAPPING

Identification and Characterization of Enhancers Controlling the Inflammatory Gene Expression Program in Macrophages

(2010) Serena Ghisletti et al.   IMMUNITY

Systemic infection and delirium: when cytokines and acetylcholine collide

(2010) Willem A van Gool et al.   LANCET

Simple Combinations of Lineage-Determining Transcription Factors Prime cis-Regulatory Elements Required for Macrophage and B Cell Identities

(2010) Sven Heinz et al.   MOLECULAR CELL

Repressive and active histone methylation mark distinct promoters in human and mouse spermatozoa

(2010) Urszula Brykczynska et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Altered adult hippocampal neurogenesis in the YAC128 transgenic mouse model of Huntington disease

(2010) Jessica M. Simpson et al.   NEUROBIOLOGY OF DISEASE

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

(2010) F. Ginhoux et al.   SCIENCE

Expressed Alu repeats as a novel, reliable tool for normalization of real-time quantitative RT-PCR data

(2010) Manuela Marullo et al.   GENOME BIOLOGY

Microglial CB2 cannabinoid receptors are neuroprotective in Huntington's disease excitotoxicity

(2009) Javier Palazuelos et al.   BRAIN

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

(2009) Kaoru Saijo et al.   CELL

Altered P2X7-receptor level and function in mouse models of Huntington’s disease and therapeutic efficacy of antagonist administration

(2009) Miguel Díaz-Hernández et al.   FASEB JOURNAL

Generation of cortical neurons from mouse embryonic stem cells

(2009) Nicolas Gaspard et al.   Nature Protocols

Distinct neuroinflammatory profile in post-mortem human Huntingtonʼs disease

(2009) Aurelio Silvestroni et al.   NEUROREPORT

Genome-Wide Analysis in Vivo of Translation with Nucleotide Resolution Using Ribosome Profiling

(2009) N. T. Ingolia et al.   SCIENCE

Non-Cell-Autonomous Effect of Human SOD1G37R Astrocytes on Motor Neurons Derived from Human Embryonic Stem Cells

(2008) Maria C.N. Marchetto et al.   Cell Stem Cell

A novel pathogenic pathway of immune activation detectable before clinical onset in Huntington's disease

(2008) Maria Björkqvist et al.   JOURNAL OF EXPERIMENTAL MEDICINE

How transcription factors program chromatin—Lessons from studies of the regulation of myeloid-specific genes

(2008) Constanze Bonifer et al.   SEMINARS IN IMMUNOLOGY