The needs of a synapse—How local organelles serve synaptic proteostasis

Presynaptic autophagy is coupled to the synaptic vesicle cycle via ATG-9

(2022) Sisi Yang et al.   NEURON

Dendritic autophagy degrades postsynaptic proteins and is required for long-term synaptic depression in mice

(2022) Emmanouela Kallergi et al.   Nature Communications

Neuronal autophagy controls the axonal endoplasmic reticulum to regulate neurotransmission in healthy neurons

(2021) Marijn Kuijpers et al.   Autophagy

Synaptic activity controls autophagic vacuole motility and function in dendrites

(2021) Vineet Vinay Kulkarni et al.   JOURNAL OF CELL BIOLOGY

NMDAR-dependent long-term depression is associated with increased short term plasticity through autophagy mediated loss of PSD-95

(2021) Benjamin Compans et al.   Nature Communications

Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons

(2021) Pearl P.Y. Lie et al.   Cell Reports

Dietary spermidine improves cognitive function

(2021) Sabrina Schroeder et al.   Cell Reports

Mechanism of synaptic protein turnover and its regulation by neuronal activity

(2021) Tolga Soykan et al.   CURRENT OPINION IN NEUROBIOLOGY

zapERtrap: A light-regulated ER release system reveals unexpected neuronal trafficking pathways

(2021) Ashley M. Bourke et al.   JOURNAL OF CELL BIOLOGY

Neuronal activity recruits the CRTC1/CREB axis to drive transcription-dependent autophagy for maintaining late-phase LTD

(2021) Yue Pan et al.   Cell Reports

Endosomal traffic and glutamate synapse activity are increased in VPS35 D620N mutant knock-in mouse neurons, and resistant to LRRK2 kinase inhibition

(2021) Chelsie A. Kadgien et al.   Molecular Brain

Activity-dependent Golgi satellite formation in dendrites reshapes the neuronal surface glycoproteome

(2021) Anitha P Govind et al.   eLife

Monitoring the glycosylation of α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazole‐propionate‐type glutamate receptors using specific antibodies reveals a novel regulatory mechanism of N‐glycosylation occupancy by molecular chaperones in mice

(2020) Ryosuke Midorikawa et al.   JOURNAL OF NEUROCHEMISTRY

Monosomes actively translate synaptic mRNAs in neuronal processes

(2020) Anne Biever et al.   SCIENCE

Lysosomal Exocytosis, Exosome Release and Secretory Autophagy: The Autophagic- and Endo-Lysosomal Systems Go Extracellular

(2020) Sandra Buratta et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cathepsin B inhibition blocks neurite outgrowth in cultured neurons by regulating lysosomal trafficking and remodeling

(2020) Muzhou Jiang et al.   JOURNAL OF NEUROCHEMISTRY

Autophagy lipidation machinery regulates axonal microtubule dynamics but is dispensable for survival of mammalian neurons

(2020) A. Negrete-Hurtado et al.   Nature Communications

Autophagy-dependent filopodial kinetics restrict synaptic partner choice during Drosophila brain wiring

(2020) Ferdi Ridvan Kiral et al.   Nature Communications

Non-conventional Axonal Organelles Control TRPM8 Ion Channel Trafficking and Peripheral Cold Sensing

(2020) Víctor Hugo Cornejo et al.   Cell Reports

Parkin contributes to synaptic vesicle autophagy in Bassoon-deficient mice

(2020) Sheila Hoffmann-Conaway et al.   eLife

Ribosome-associated vesicles: A dynamic subcompartment of the endoplasmic reticulum in secretory cells

(2020) Stephen D. Carter et al.   Science Advances

Linking glutamate receptor movements and synapse function

(2020) Laurent Groc et al.   SCIENCE

Autophagy controls the induction and developmental decline of NMDAR-LTD through endocytic recycling

(2020) Hongmei Shen et al.   Nature Communications

Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons

(2020) Raffaella De Pace et al.   Cell Reports

Autophagy and the endolysosomal system in presynaptic function

(2020) Maria Andres-Alonso et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum

(2020) Marijn Kuijpers et al.   NEURON

Sorting nexin 27 rescues neuroligin 2 from lysosomal degradation to control inhibitory synapse number

(2019) Caroline Binda et al.   BIOCHEMICAL JOURNAL

Autophagy Is Required for Memory Formation and Reverses Age-Related Memory Decline

(2019) Mélissa Glatigny et al.   CURRENT BIOLOGY

GPN does not release lysosomal Ca2+, but evokes ER Ca2+ release by increasing cytosolic pH independent of cathepsin C

(2019) Peace Atakpa et al.   JOURNAL OF CELL SCIENCE

Light-activated ROS production induces synaptic autophagy

(2019) Sheila Hoffmann et al.   JOURNAL OF NEUROSCIENCE

Mechanisms of postsynaptic localization of AMPA-type glutamate receptors and their regulation during long-term potentiation

(2019) Olivia R. Buonarati et al.   Science Signaling

Chaperone Mediated Autophagy in the Crosstalk of Neurodegenerative Diseases and Metabolic Disorders

(2019) Iván E. Alfaro et al.   Frontiers in Endocrinology

Autophagy within the mushroom body protects from synapse aging in a non-cell autonomous manner

(2019) Anuradha Bhukel et al.   Nature Communications

Activity-Dependent Secretion of Synaptic Organizer Cbln1 from Lysosomes in Granule Cell Axons

(2019) Keiji Ibata et al.   NEURON

Local protein synthesis is a ubiquitous feature of neuronal pre- and postsynaptic compartments

(2019) Anne-Sophie Hafner et al.   SCIENCE

mTORC1 Signaling Is Palmitoylation-Dependent in Hippocampal Neurons and Non-neuronal Cells and Involves Dynamic Palmitoylation of LAMTOR1 and mTOR

(2019) Shaun S. Sanders et al.   Frontiers in Cellular Neuroscience

Architecture and Dynamics of the Neuronal Secretory Network

(2019) Matthew J. Kennedy et al.   Annual Review of Cell and Developmental Biology

Autophagy in Neurons

(2019) Andrea K.H. Stavoe et al.   Annual Review of Cell and Developmental Biology

F‐actin patches associated with glutamatergic synapses control positioning of dendritic lysosomes

(2019) Bas Bommel et al.   EMBO JOURNAL

Local translation in neurons: visualization and function

(2019) Christine E. Holt et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

SynGO: An Evidence-Based, Expert-Curated Knowledge Base for the Synapse

(2019) Frank Koopmans et al.   NEURON

Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy

(2019) Yuan-Li Chen et al.   Nature Communications

Neuronal Soma-Derived Degradative Lysosomes Are Continuously Delivered to Distal Axons to Maintain Local Degradation Capacity

(2019) Tamar Farfel-Becker et al.   Cell Reports

The secret life of degradative lysosomes in axons: delivery from the soma, enzymatic activity, and local autophagic clearance

(2019) Tamar Farfel-Becker et al.   Autophagy

Super-resolution imaging and estimation of protein copy numbers at single synapses with DNA-point accumulation for imaging in nanoscale topography

(2019) Carolin Böger et al.   Neurophotonics

Exocytosis of large-diameter lysosomes mediates interferon γ-induced relocation of MHC class II molecules toward the surface of astrocytes

(2019) Mićo Božić et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Cellular quality control by the ubiquitin-proteasome system and autophagy

(2019) Christian Pohl et al.   SCIENCE

SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals

(2019) Maria Andres-Alonso et al.   Nature Communications

Does lysosomal rupture evoke Ca2+ release? A question of pores and stores

(2019) Anthony J. Morgan et al.   CELL CALCIUM

Spermidine protects from age-related synaptic alterations at hippocampal mossy fiber-CA3 synapses

(2019) Marta Maglione et al.   Scientific Reports

Atg9a deficiency causes axon-specific lesions including neuronal circuit dysgenesis

(2018) Junji Yamaguchi et al.   Autophagy

Live Observation of Two Parallel Membrane Degradation Pathways at Axon Terminals

(2018) Eugene Jennifer Jin et al.   CURRENT BIOLOGY

Rab GTPases and Membrane Trafficking in Neurodegeneration

(2018) Ferdi Ridvan Kiral et al.   CURRENT BIOLOGY

Autophagy and proteostasis in the control of synapse aging and disease

(2018) YongTian Liang et al.   CURRENT OPINION IN NEUROBIOLOGY

Newly produced synaptic vesicle proteins are preferentially used in synaptic transmission

(2018) Sven Truckenbrodt et al.   EMBO JOURNAL

mTORC1 and Nutrient Homeostasis: The Central Role of the Lysosome

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons

(2018) Xiu-Tang Cheng et al.   JOURNAL OF CELL BIOLOGY

Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes

(2018) Chan Choo Yap et al.   JOURNAL OF CELL BIOLOGY

The enigmatic endosome – sorting the ins and outs of endocytic trafficking

(2018) Naava Naslavsky et al.   JOURNAL OF CELL SCIENCE

Modulation of receptor protein tyrosine phosphatase sigma increases chondroitin sulfate proteoglycan degradation through Cathepsin B secretion to enhance axon outgrowth

(2018) Amanda Phuong Tran et al.   JOURNAL OF NEUROSCIENCE

Trafficking mechanisms of synaptogenic cell adhesion molecules

(2018) Luís F. Ribeiro et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Regulation of AMPA receptor trafficking and exit from the endoplasmic reticulum

(2018) Joseph E. Pick et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Mechanism and medical implications of mammalian autophagy

(2018) Ivan Dikic et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy as a promoter of longevity: insights from model organisms

(2018) Malene Hansen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Axonal autophagy: Mini-review for autophagy in the CNS

(2018) Andrea K.H. Stavoe et al.   NEUROSCIENCE LETTERS

Maintaining the active zone: Demand, supply and disposal of core active zone proteins

(2018) Noam E. Ziv   NEUROSCIENCE RESEARCH

Intermediate compartment (IC): from pre-Golgi vacuoles to a semi-autonomous membrane system

(2018) Jaakko Saraste et al.   HISTOCHEMISTRY AND CELL BIOLOGY

N-glycosylation of the AMPA-type glutamate receptor regulates cell surface expression and tetramer formation affecting channel function

(2018) Munal Babu Kandel et al.   JOURNAL OF NEUROCHEMISTRY

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles

(2018) Anela Vukoja et al.   NEURON

Linking Nanoscale Dynamics of AMPA Receptor Organization to Plasticity of Excitatory Synapses and Learning

(2018) Daniel Choquet   JOURNAL OF NEUROSCIENCE

The lysosome as a cellular centre for signalling, metabolism and quality control

(2018) Rosalie E. Lawrence et al.   NATURE CELL BIOLOGY

Hippocampal mGluR1-dependent long-term potentiation requires NAADP-mediated acidic store Ca2+ signaling

(2018) William J. Foster et al.   Science Signaling

Activity-dependent trafficking of lysosomes in dendrites and dendritic spines

(2017) Marisa S. Goo et al.   JOURNAL OF CELL BIOLOGY

Unconventional secretion of FABP4 by endosomes and secretory lysosomes

(2017) Julien Villeneuve et al.   JOURNAL OF CELL BIOLOGY

Autophagy in the presynaptic compartment in health and disease

(2017) Vinoy Vijayan et al.   JOURNAL OF CELL BIOLOGY

The Dopamine Transporter Recycles via a Retromer-Dependent Postendocytic Mechanism: Tracking Studies Using a Novel Fluorophore-Coupling Approach

(2017) Sijia Wu et al.   JOURNAL OF NEUROSCIENCE

Neurodegeneration-associated mutant TREM2 proteins abortively cycle between the ER and ER–Golgi intermediate compartment

(2017) Daniel W. Sirkis et al.   MOLECULAR BIOLOGY OF THE CELL

Activity-Dependent Exocytosis of Lysosomes Regulates the Structural Plasticity of Dendritic Spines

(2017) Zahid Padamsey et al.   NEURON

The Retromer Supports AMPA Receptor Trafficking During LTP

(2017) Paul Temkin et al.   NEURON

BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon

(2017) Ginny G. Farías et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

mTORC1 activity repression by late endosomal phosphatidylinositol 3,4-bisphosphate

(2017) Andrea L. Marat et al.   SCIENCE

Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration

(2017) Natalia L. Kononenko et al.   Nature Communications

Plekhg5-regulated autophagy of synaptic vesicles reveals a pathogenic mechanism in motoneuron disease

(2017) Patrick Lüningschrör et al.   Nature Communications

Assembly, Secretory Pathway Trafficking, and Surface Delivery of Kainate Receptors Is Regulated by Neuronal Activity

(2017) Ashley J. Evans et al.   Cell Reports

Golgi-independent secretory trafficking through recycling endosomes in neuronal dendrites and spines

(2017) Aaron B Bowen et al.   eLife

A plasmid-based expression system to study protein–protein interactions at the Golgi in vivo

(2016) Sujoy Bera et al.   ANALYTICAL BIOCHEMISTRY

Mechanisms of neuronal homeostasis: Autophagy in the axon

(2016) Sandra Maday   BRAIN RESEARCH

Retromer Endosome Exit Domains Serve Multiple Trafficking Destinations and Regulate Local G Protein Activation by GPCRs

(2016) Katherine C. Varandas et al.   CURRENT BIOLOGY

Specialization of biosynthetic membrane trafficking for neuronal form and function

(2016) Cyril Hanus et al.   CURRENT OPINION IN NEUROBIOLOGY

The effects of proteasomal inhibition on synaptic proteostasis

(2016) Vicky Hakim et al.   EMBO JOURNAL

Activity-Dependent Degradation of Synaptic Vesicle Proteins Requires Rab35 and the ESCRT Pathway

(2016) Patricia Sheehan et al.   JOURNAL OF NEUROSCIENCE

Compartment-Specific Regulation of Autophagy in Primary Neurons

(2016) Sandra Maday et al.   JOURNAL OF NEUROSCIENCE

The Noncanonical Role of ULK/ATG1 in ER-to-Golgi Trafficking Is Essential for Cellular Homeostasis

(2016) Joung Hyuck Joo et al.   MOLECULAR CELL

Cardioprotection and lifespan extension by the natural polyamine spermidine

(2016) Tobias Eisenberg et al.   NATURE MEDICINE

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

VPS35 regulates cell surface recycling and signaling of dopamine receptor D1

(2016) Chen Wang et al.   NEUROBIOLOGY OF AGING

A LRRK2-Dependent EndophilinA Phosphoswitch Is Critical for Macroautophagy at Presynaptic Terminals

(2016) Sandra-Fausia Soukup et al.   NEURON

Ubiquitin-Dependent And Independent Signals In Selective Autophagy

(2016) Aliaksandr Khaminets et al.   TRENDS IN CELL BIOLOGY

A molecular code for endosomal recycling of phosphorylated cargos by the SNX27–retromer complex

(2016) Thomas Clairfeuille et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A Dendritic Golgi Satellite between ERGIC and Retromer

(2016) Marina Mikhaylova et al.   Cell Reports

Lysosomal iron modulates NMDA receptor-mediated excitation via small GTPase, Dexras1

(2016) Rachel S. White et al.   Molecular Brain

Spermidine Suppresses Age-Associated Memory Impairment by Preventing Adverse Increase of Presynaptic Active Zone Size and Release

(2016) Varun K. Gupta et al.   PLOS BIOLOGY

Dendritic trafficking faces physiologically critical speed-precision tradeoffs

(2016) Alex H Williams et al.   eLife

Unconventional secretory processing diversifies neuronal ion channel properties

(2016) Cyril Hanus et al.   eLife

Multiple Roles of the Small GTPase Rab7

(2016) Flora Guerra et al.   Cells

Local protein synthesis in neuronal axons: why and how we study

(2015) Eunjin Kim et al.   BMB Reports

Release of calcium from endolysosomes increases calcium influx through N-type calcium channels: Evidence for acidic store-operated calcium entry in neurons

(2015) Liang Hui et al.   CELL CALCIUM

A RhoA Signaling Pathway Regulates Dendritic Golgi Outpost Formation

(2015) Gonzalo Quassollo et al.   CURRENT BIOLOGY

Secretory autophagy

(2015) Marisa Ponpuak et al.   CURRENT OPINION IN CELL BIOLOGY

ER-endosome contact sites: molecular compositions and functions

(2015) C. Raiborg et al.   EMBO JOURNAL

Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomes

(2015) Xiu-Tang Cheng et al.   JOURNAL OF CELL BIOLOGY

Autophagy: a druggable process that is deregulated in aging and human disease

(2015) Guido Kroemer   JOURNAL OF CLINICAL INVESTIGATION

Control of Autophagosome Axonal Retrograde Flux by Presynaptic Activity Unveiled Using Botulinum Neurotoxin Type A

(2015) Tong Wang et al.   JOURNAL OF NEUROSCIENCE

Proteomics of the Synapse – A Quantitative Approach to Neuronal Plasticity

(2015) Daniela C. Dieterich et al.   MOLECULAR & CELLULAR PROTEOMICS

Repeated ER–endosome contacts promote endosome translocation and neurite outgrowth

(2015) Camilla Raiborg et al.   NATURE

Role of Site-Specific N-Glycans Expressed on GluA2 in the Regulation of Cell Surface Expression of AMPA-Type Glutamate Receptors

(2015) Yusuke Takeuchi et al.   PLoS One

VPS35-deficiency results in an impaired AMPA receptor trafficking and decreased dendritic spine maturation

(2015) Yun Tian et al.   Molecular Brain

The GTPase Rab26 links synaptic vesicles to the autophagy pathway

(2015) Beyenech Binotti et al.   eLife

GM130 Is Required for Compartmental Organization of Dendritic Golgi Outposts

(2014) Wei Zhou et al.   CURRENT BIOLOGY

Autophagosome Biogenesis in Primary Neurons Follows an Ordered and Spatially Regulated Pathway

(2014) Sandra Maday et al.   DEVELOPMENTAL CELL

Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N

(2014) L. N. Munsie et al.   HUMAN MOLECULAR GENETICS

Mitophagy of damaged mitochondria occurs locally in distal neuronal axons and requires PINK1 and Parkin

(2014) Ghazaleh Ashrafi et al.   JOURNAL OF CELL BIOLOGY

γ-Tubulin controls neuronal microtubule polarity independently of Golgi outposts

(2014) Michelle M. Nguyen et al.   MOLECULAR BIOLOGY OF THE CELL

Retromer Mediates a Discrete Route of Local Membrane Delivery to Dendrites

(2014) Regina Wai-Yan Choy et al.   NEURON

GRIP1 interlinks N-cadherin and AMPA receptors at vesicles to promote combined cargo transport into dendrites

(2014) Frank F. Heisler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Composition of isolated synaptic boutons reveals the amounts of vesicle trafficking proteins

(2014) B. G. Wilhelm et al.   SCIENCE

Retromer: A Master Conductor of Endosome Sorting

(2014) C. Burd et al.   Cold Spring Harbor Perspectives in Biology

The Biogenesis of Lysosomes and Lysosome-Related Organelles

(2014) J. P. Luzio et al.   Cold Spring Harbor Perspectives in Biology

Synaptic Control of Secretory Trafficking in Dendrites

(2014) Cyril Hanus et al.   Cell Reports

Lifespan Extension by Methionine Restriction Requires Autophagy-Dependent Vacuolar Acidification

(2014) Christoph Ruckenstuhl et al.   PLoS Genetics

Beclin 1 Is Required for Neuron Viability and Regulates Endosome Pathways via the UVRAG-VPS34 Complex

(2014) Nicole C. McKnight et al.   PLoS Genetics

GluN2B-containing NMDA receptors regulate depression-like behavior and are critical for the rapid antidepressant actions of ketamine

(2014) Oliver H Miller et al.   eLife

The roles of protein expression in synaptic plasticity and memory consolidation

(2014) Tali Rosenberg et al.   Frontiers in Molecular Neuroscience

Discovery of a novel type of autophagy targeting RNA

(2013) Yuuki Fujiwara et al.   Autophagy

A TRP Channel in the Lysosome Regulates Large Particle Phagocytosis via Focal Exocytosis

(2013) Mohammad Samie et al.   DEVELOPMENTAL CELL

Tubulin Polymerization-promoting Protein (TPPP/p25α) Promotes Unconventional Secretion of α-Synuclein through Exophagy by Impairing Autophagosome-Lysosome Fusion

(2013) Patrick Ejlerskov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteostasis in complex dendrites

(2013) Cyril Hanus et al.   NATURE REVIEWS NEUROSCIENCE

The Dynamic Synapse

(2013) Daniel Choquet et al.   NEURON

Regulation of ubiquitin-dependent cargo sorting by multiple endocytic adaptors at the plasma membrane

(2013) J. R. Mayers et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of Atg5 in mice activates autophagy and extends lifespan

(2013) Jong-Ok Pyo et al.   Nature Communications

The ER–Golgi intermediate compartment is a key membrane source for the LC3 lipidation step of autophagosome biogenesis

(2013) Liang Ge et al.   eLife

Local Zones of Endoplasmic Reticulum Complexity Confine Cargo in Neuronal Dendrites

(2012) Tingting Cui-Wang et al.   CELL

Ubiquitination and selective autophagy

(2012) S Shaid et al.   CELL DEATH AND DIFFERENTIATION

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

RAB-6.2 and the retromer regulate glutamate receptor recycling through a retrograde pathway

(2012) Donglei Zhang et al.   JOURNAL OF CELL BIOLOGY

Neuronal Stimulation Induces Autophagy in Hippocampal Neurons That Is Involved in AMPA Receptor Degradation after Chemical Long-Term Depression

(2012) M. Shehata et al.   JOURNAL OF NEUROSCIENCE

Vertebrate protein glycosylation: diversity, synthesis and function

(2012) Kelley W. Moremen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Axonal mRNA localization and local protein synthesis in nervous system assembly, maintenance and repair

(2012) Hosung Jung et al.   NATURE REVIEWS NEUROSCIENCE

Golgi Outposts Shape Dendrite Morphology by Functioning as Sites of Acentrosomal Microtubule Nucleation in Neurons

(2012) Kassandra M. Ori-McKenney et al.   NEURON

Regulation of Presynaptic Neurotransmission by Macroautophagy

(2012) Daniela Hernandez et al.   NEURON

The Local Transcriptome in the Synaptic Neuropil Revealed by Deep Sequencing and High-Resolution Imaging

(2012) Iván J. Cajigas et al.   NEURON

The trafficking proteins Vacuolar Protein Sorting 35 and Neurobeachin interact with the glycine receptor β-subunit

(2011) Isabel del Pino et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Molecular mechanisms of endolysosomal Ca2+signalling in health and disease

(2011) Anthony J. Morgan et al.   BIOCHEMICAL JOURNAL

Loss of Skywalker Reveals Synaptic Endosomes as Sorting Stations for Synaptic Vesicle Proteins

(2011) Valerie Uytterhoeven et al.   CELL

Calcium Triggers Exocytosis from Two Types of Organelles in a Single Astrocyte

(2011) T. Liu et al.   JOURNAL OF NEUROSCIENCE

A Critical Role for GluN2B-Containing NMDA Receptors in Cortical Development and Function

(2011) Chih-Chieh Wang et al.   NEURON

The endoplasmic reticulum and protein trafficking in dendrites and axons

(2011) Omar A. Ramírez et al.   TRENDS IN CELL BIOLOGY

Ric-3 Promotes  7 Nicotinic Receptor Assembly and Trafficking through the ER Subcompartment of Dendrites

(2010) J. K. Alexander et al.   JOURNAL OF NEUROSCIENCE

Genome-wide analysis reveals mechanisms modulating autophagy in normal brain aging and in Alzheimer's disease

(2010) M. M. Lipinski et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Deletion of PIK3C3/Vps34 in sensory neurons causes rapid neurodegeneration by disrupting the endosomal but not the autophagic pathway

(2010) X. Zhou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The proteome of lysosomes

(2010) Bernd A. Schröder et al.   PROTEOMICS

Acidic calcium stores open for business: expanding the potential for intracellular Ca2+ signaling

(2010) Sandip Patel et al.   TRENDS IN CELL BIOLOGY

Recruitment of NAADP-sensitive acidic Ca2+stores by glutamate

(2009) Vinita Pandey et al.   BIOCHEMICAL JOURNAL

Neural-specific Deletion of FIP200 Leads to Cerebellar Degeneration Caused by Increased Neuronal Death and Axon Degeneration

(2009) Chun-Chi Liang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The ESCRT machinery in endosomal sorting of ubiquitylated membrane proteins

(2009) Camilla Raiborg et al.   NATURE

SAP97 and CASK mediate sorting of NMDA receptors through a previously unknown secretory pathway

(2009) Okunola Jeyifous et al.   NATURE NEUROSCIENCE

Brain extracellular matrix affects AMPA receptor lateral mobility and short-term synaptic plasticity

(2009) Renato Frischknecht et al.   NATURE NEUROSCIENCE

Lysosome biogenesis and lysosomal membrane proteins: trafficking meets function

(2009) Paul Saftig et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Calneurons provide a calcium threshold for trans-Golgi network to plasma membrane trafficking

(2009) M. Mikhaylova et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Modeling the role of lateral membrane diffusion in AMPA receptor trafficking along a spiny dendrite

(2008) B. A. Earnshaw et al.   JOURNAL OF COMPUTATIONAL NEUROSCIENCE

Ubiquitin, the proteasome and protein degradation in neuronal function and dysfunction

(2008) Hwan-Ching Tai et al.   NATURE REVIEWS NEUROSCIENCE