Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics
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Title
Gene–environment interactions in Alzheimer disease: the emerging role of epigenetics
Authors
Keywords
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Journal
Nature Reviews Neurology
Volume 18, Issue 11, Pages 643-660
Publisher
Springer Science and Business Media LLC
Online
2022-09-30
DOI
10.1038/s41582-022-00714-w
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Note: Only part of the references are listed.- Genome-Wide DNA Methylation in Policemen Working in Cities Differing by Major Sources of Air Pollution
- (2022) Katerina Honkova et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Association of prenatal alcohol exposure with offspring DNA methylation in mammals: a systematic review of the evidence
- (2022) Mitchell Bestry et al. Clinical Epigenetics
- Early-Life Environment Influence on Late-Onset Alzheimer’s Disease
- (2022) Thibaut Gauvrit et al. Frontiers in Cell and Developmental Biology
- Early-Onset Alzheimer’s Disease: What Is Missing in Research?
- (2021) Temitope Ayodele et al. Current Neurology and Neuroscience Reports
- Apolipoprotein E Polymorphism and Oxidative Stress in Human Peripheral Blood Cells: Can Physical Activity Reactivate the Proteasome System through Epigenetic Mechanisms?
- (2021) Rebecca Piccarducci et al. Oxidative Medicine and Cellular Longevity
- Resveratrol Supplementation Attenuates Cognitive and Molecular Alterations under Maternal High-Fat Diet Intake: Epigenetic Inheritance over Generations
- (2021) Vanesa Izquierdo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Genome-wide meta-analysis, fine-mapping and integrative prioritization implicate new Alzheimer’s disease risk genes
- (2021) Jeremy Schwartzentruber et al. NATURE GENETICS
- Potential of Caffeine in Alzheimer’s Disease—A Review of Experimental Studies
- (2021) Piotr Londzin et al. Nutrients
- A Meta-Analysis of Brain DNA Methylation Across Sex, Age, and Alzheimer's Disease Points for Accelerated Epigenetic Aging in Neurodegeneration
- (2021) Camilla Pellegrini et al. Frontiers in Aging Neuroscience
- Systematic Review of Nicotine Exposure’s Effects on Neural Stem and Progenitor Cells
- (2021) Arrin C. Brooks et al. Brain Sciences
- The pleiotropic neuroprotective effects of resveratrol in cognitive decline and Alzheimer’s disease pathology: From antioxidant to epigenetic therapy
- (2021) Christian Griñán-Ferré et al. AGEING RESEARCH REVIEWS
- Epigenetic regulation in Alzheimer’s disease: is it a potential therapeutic target?
- (2021) Fabio Coppedè EXPERT OPINION ON THERAPEUTIC TARGETS
- Gut Microbiota Composition and Epigenetic Molecular Changes Connected to the Pathogenesis of Alzheimer’s Disease
- (2021) Priyanka Nagu et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Genome-wide associations between alcohol consumption and blood DNA methylation: evidence from twin study
- (2021) Meng Lu et al. Epigenomics
- The Effects of Education on Cognition in Older Age: Evidence from Genotyped Siblings1
- (2021) Jason Fletcher et al. SOCIAL SCIENCE & MEDICINE
- Sex-specific DNA methylation differences in Alzheimer’s disease pathology
- (2021) Lanyu Zhang et al. Acta Neuropathologica Communications
- Dysbiosis and Alzheimer’s Disease: A Role for Chronic Stress?
- (2021) Vivek Kumar Sharma et al. Biomolecules
- miR-29a/b1 Regulates BACE1 in Aluminum-Induced Aβ Deposition in Vitro
- (2021) Huan Li et al. ACS Chemical Neuroscience
- APOE Genotype and Alzheimer’s Disease: The Influence of Lifestyle and Environmental Factors
- (2021) Efthalia Angelopoulou et al. ACS Chemical Neuroscience
- Western diet as a trigger of Alzheimer’s disease: From metabolic syndrome and systemic inflammation to neuroinflammation and neurodegeneration
- (2021) Angelika Więckowska-Gacek et al. AGEING RESEARCH REVIEWS
- Novel DNA methylation loci and genes showing pleiotropic association with Alzheimer’s dementia: a network Mendelian randomization analysis
- (2021) Di Liu et al. Epigenetics
- Interaction of Alzheimer’s Disease-Associated Genetic Risk with Indicators of Socioeconomic Position on Mild Cognitive Impairment in the Heinz Nixdorf Recall Study
- (2021) Mirjam Frank et al. JOURNAL OF ALZHEIMERS DISEASE
- The Mediterranean diet and health: a comprehensive overview
- (2021) M. Guasch‐Ferré et al. JOURNAL OF INTERNAL MEDICINE
- A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer’s disease
- (2021) Douglas P. Wightman et al. NATURE GENETICS
- Identifying individuals with high risk of Alzheimer’s disease using polygenic risk scores
- (2021) Ganna Leonenko et al. Nature Communications
- A meta-analysis of epigenome-wide association studies in Alzheimer’s disease highlights novel differentially methylated loci across cortex
- (2021) Rebecca G. Smith et al. Nature Communications
- A machine learning approach to brain epigenetic analysis reveals kinases associated with Alzheimer’s disease
- (2021) Yanting Huang et al. Nature Communications
- Multi-omics integration analysis identifies novel genes for alcoholism with potential overlap with neurodegenerative diseases
- (2021) Manav Kapoor et al. Nature Communications
- Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
- (2021) Itziar de Rojas et al. Nature Communications
- Probability of Alzheimer’s disease based on common and rare genetic variants
- (2021) Valentina Escott-Price et al. Alzheimers Research & Therapy
- Roles and Mechanisms of Gut Microbiota in Patients With Alzheimer’s Disease
- (2021) Shaochang Wu et al. Frontiers in Aging Neuroscience
- Operationalizing Social Environments in Cognitive Aging and Dementia Research: A Scoping Review
- (2021) Rachel L. Peterson et al. International Journal of Environmental Research and Public Health
- Genetic and Epigenetic Alterations Induced by Pesticide Exposure: Integrated Analysis of Gene Expression, microRNA Expression, and DNA Methylation Datasets
- (2021) Federica Giambò et al. International Journal of Environmental Research and Public Health
- Association of APOE ε4 genotype and lifestyle with cognitive function among Chinese adults aged 80 years and older: A cross-sectional study
- (2021) Xurui Jin et al. PLOS MEDICINE
- Predictability of polygenic risk score for progression to dementia and its interaction with APOE ε4 in mild cognitive impairment
- (2021) Jung-Min Pyun et al. Translational Neurodegeneration
- Genetic and environmental factors in Alzheimer’s and Parkinson’s diseases and promising therapeutic intervention via fecal microbiota transplantation
- (2021) Hui Wang et al. npj Parkinsons Disease
- Socioeconomic Position and Late-Onset Dementia: A Nationwide Register-Based Study
- (2021) Andreas M. Appel et al. JOURNAL OF AGING AND HEALTH
- Identification of epigenetic modifications mediating the antagonistic effect of selenium against cadmium-induced breast carcinogenesis
- (2021) Zhuo-Zhi Liang et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- A gene–environment interplay between omega‐3 supplementation and APOE ε4 provides insights for Alzheimer’s disease precise prevention amongst high‐genetic‐risk population
- (2021) Lin Li et al. EUROPEAN JOURNAL OF NEUROLOGY
- Interactions between dietary patterns and genetic factors in relation to incident dementia among 70-year-olds
- (2021) Jessica Samuelsson et al. EUROPEAN JOURNAL OF NUTRITION
- Education and Cardiovascular Health as Effect Modifiers of APOE ε4 on Dementia: The Atherosclerosis Risk in Communities (ARIC) Study
- (2021) Mark Lee et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Emerging roles of oxidative stress in brain aging and Alzheimer's disease
- (2021) Andra Ionescu-Tucker et al. NEUROBIOLOGY OF AGING
- Interaction of greenness and polygenic risk score of Alzheimer's disease on risk of cognitive impairment
- (2021) Xurui Jin et al. SCIENCE OF THE TOTAL ENVIRONMENT
- Validating biomarkers and models for epigenetic inference of alcohol consumption from blood
- (2021) Silvana C. E. Maas et al. Clinical Epigenetics
- The Promises and Challenges of Toxico-Epigenomics: Environmental Chemicals and Their Impacts on the Epigenome
- (2020) Felicia Fei-Lei Chung et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- CpG and non-CpG Presenilin1 methylation pattern in course of neurodevelopment and neurodegeneration is associated with gene expression in human and murine brain
- (2020) Noemi Monti et al. Epigenetics
- Chronic Mild Stress Modified Epigenetic Mechanisms Leading to Accelerated Senescence and Impaired Cognitive Performance in Mice
- (2020) Dolors Puigoriol-Illamola et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Physical activity as moderator of the association between APOE and cognitive decline in older adults: Results from three longitudinal cohort studies
- (2020) Najada Stringa et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- The multiplex model of the genetics of Alzheimer’s disease
- (2020) Rebecca Sims et al. NATURE NEUROSCIENCE
- Dietary flavonols and risk of Alzheimer dementia
- (2020) Thomas M. Holland et al. NEUROLOGY
- Pesticides, cognitive functions and dementia: A review
- (2020) Athina-Maria Aloizou et al. TOXICOLOGY LETTERS
- Epigenome signatures landscaped by histone H3K9me3 are associated with the synaptic dysfunction in Alzheimer's disease
- (2020) Min Young Lee et al. AGING CELL
- Adherence to a Mediterranean diet and cognitive function in the Age-Related Eye Disease Studies 1 & 2
- (2020) Tiarnán D. Keenan et al. Alzheimers & Dementia
- Reduced repressive epigenetic marks, increased DNA damage and Alzheimer's disease hallmarks in the brain of humans and mice exposed to particulate urban air pollution
- (2020) Lilian Calderón-Garcidueñas et al. ENVIRONMENTAL RESEARCH
- Emerging risk of environmental factors: insight mechanisms of Alzheimer’s diseases
- (2020) Md Ataur Rahman et al. ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH
- Influence of Western diet and APOE genotype on Alzheimer's disease risk
- (2020) P.M. Sullivan NEUROBIOLOGY OF DISEASE
- Advances in the In vitro and In vivo pharmacology of Alpha4beta2 nicotinic receptor positive allosteric modulators
- (2020) Jenny L. Wilkerson et al. NEUROPHARMACOLOGY
- Single cell analysis of the gene expression effects of developmental lead (Pb) exposure on the mouse hippocampus
- (2020) Kelly M Bakulski et al. TOXICOLOGICAL SCIENCES
- Heavy Metals Exposure and Alzheimer’s Disease and Related Dementias
- (2020) Kelly M. Bakulski et al. JOURNAL OF ALZHEIMERS DISEASE
- Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
- (2020) Gill Livingston et al. LANCET
- Impact of nicotine, alcohol, and cocaine exposure on germline integrity and epigenome
- (2020) Dana Zeid et al. NEUROPHARMACOLOGY
- Mediterranean Diet and Telomere Length: A Systematic Review and Meta-Analysis
- (2020) Silvia Canudas et al. Advances in Nutrition
- APOE Alleles and Diet in Brain Aging and Alzheimer’s Disease
- (2020) Hussein N. Yassine et al. Frontiers in Aging Neuroscience
- Epigenetic Basis of Lead-Induced Neurological Disorders
- (2020) Tian Wang et al. International Journal of Environmental Research and Public Health
- Harnessing peripheral DNA methylation differences in the Alzheimer’s Disease Neuroimaging Initiative (ADNI) to reveal novel biomarkers of disease
- (2020) Aparna Vasanthakumar et al. Clinical Epigenetics
- The Role of Dietary Phenolic Compounds in Epigenetic Modulation Involved in Inflammatory Processes
- (2020) Milan Číž et al. Antioxidants
- Hippocampal and cortical tissue-specific epigenetic clocks indicate an increased epigenetic age in a mouse model for Alzheimer’s disease
- (2020) Emma Coninx et al. Aging-US
- An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer’s disease
- (2020) Raffaella Nativio et al. NATURE GENETICS
- The evolving metabolic landscape of chromatin biology and epigenetics
- (2020) Ziwei Dai et al. NATURE REVIEWS GENETICS
- Neonatal Lead (Pb) Exposure and DNA Methylation Profiles in Dried Bloodspots
- (2020) Luke Montrose et al. International Journal of Environmental Research and Public Health
- Late-onset vs nonmendelian early-onset Alzheimer disease
- (2020) Christiane Reitz et al. Neurology-Genetics
- One-carbon epigenetics and redox biology of neurodegeneration
- (2020) Fabio Coppedè FREE RADICAL BIOLOGY AND MEDICINE
- Associations Between Caffeine Consumption, Cognitive Decline, and Dementia: A Systematic Review
- (2020) J.Q. Alida Chen et al. JOURNAL OF ALZHEIMERS DISEASE
- Mendelian randomization integrating GWAS and mQTL data identified novel pleiotropic DNA methylation loci for neuropathology of Alzheimer’s disease
- (2020) Di Liu et al. NEUROBIOLOGY OF AGING
- Epigenetic influence of environmentally neurotoxic metals
- (2020) Omamuyovwi M. Ijomone et al. NEUROTOXICOLOGY
- Arsenic-induced changes in miRNA expression in cancer and other diseases
- (2020) Ana P. Ferragut Cardoso et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- DNA methylation analysis of candidate genes associated with dementia in peripheral blood
- (2020) Peter D Fransquet et al. Epigenomics
- Epigenome-wide meta-analysis of DNA methylation differences in prefrontal cortex implicates the immune processes in Alzheimer’s disease
- (2020) Lanyu Zhang et al. Nature Communications
- The Reversion of cg05575921 Methylation in Smoking Cessation: A Potential Tool for Incentivizing Healthy Aging
- (2020) Robert Philibert et al. Genes
- The Involvement of Metals in Alzheimer’s Disease Through Epigenetic Mechanisms
- (2020) Menghua Cai et al. Frontiers in Genetics
- Effect of aluminum combined with ApoEε4 on Tau phosphorylation and Aβ deposition
- (2020) Yanni Wang et al. JOURNAL OF TRACE ELEMENTS IN MEDICINE AND BIOLOGY
- Metal Toxicity Links to Alzheimer’s Disease and Neuroinflammation
- (2019) Tee Jong Huat et al. JOURNAL OF MOLECULAR BIOLOGY
- The Role of Vitamins in Autism Spectrum Disorder: What Do We Know?
- (2019) Geir Bjørklund et al. JOURNAL OF MOLECULAR NEUROSCIENCE
- Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
- (2019) Iris E. Jansen et al. NATURE GENETICS
- Epigenome-wide association study of serum cotinine in current smokers reveals novel genetically driven loci
- (2019) Richa Gupta et al. Clinical Epigenetics
- Epigenetic and Neurological Impairments Associated with Early Life Exposure to Persistent Organic Pollutants
- (2019) Nathalie Grova et al. International Journal of Genomics
- Histone Modifications as an Intersection Between Diet and Longevity
- (2019) Diego Molina-Serrano et al. Frontiers in Genetics
- Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease
- (2019) Adam R. Smith et al. Clinical Epigenetics
- Occupational Exposures and Neurodegenerative Diseases—A Systematic Literature Review and Meta-Analyses
- (2019) Lars-Gunnar Gunnarsson et al. International Journal of Environmental Research and Public Health
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
- (2019) Brian W. Kunkle et al. NATURE GENETICS
- Air Pollution and Dementia: A Systematic Review
- (2019) Ruth Peters et al. JOURNAL OF ALZHEIMERS DISEASE
- Inhibition of EHMT1/2 rescues synaptic and cognitive functions for Alzheimer’s disease
- (2019) Yan Zheng et al. BRAIN
- Therapeutic potentials of plant iridoids in Alzheimer's and Parkinson's diseases: A review
- (2019) Biswanath Dinda et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Epigenetic response profiles into environmental epigenotoxicant screening and health risk assessment: A critical review
- (2019) Junjie Hu et al. CHEMOSPHERE
- A review of the possible associations between ambient PM2.5 exposures and the development of Alzheimer's disease
- (2019) Yikai Shou et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- The Role of Environmental Exposures and the Epigenome in Health and Disease
- (2019) Bambarendage P.U. Perera et al. ENVIRONMENTAL AND MOLECULAR MUTAGENESIS
- Multigenerational and Transgenerational Effects of Dioxins
- (2019) Matti Viluksela et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Advances in epigenetics link genetics to the environment and disease
- (2019) Giacomo Cavalli et al. NATURE
- Apolipoprotein E and Alzheimer disease: pathobiology and targeting strategies
- (2019) Yu Yamazaki et al. Nature Reviews Neurology
- Neurotoxicity of low-level lead exposure: History, mechanisms of action, and behavioral effects in humans and preclinical models
- (2019) Angelica Rocha et al. NEUROTOXICOLOGY
- Phytochemicals in cancer prevention: modulating epigenetic alterations of DNA methylation
- (2019) Sevinci Pop et al. PHYTOCHEMISTRY REVIEWS
- Role of Resveratrol and Selenium on Oxidative Stress and Expression of Antioxidant and Anti-Aging Genes in Immortalized Lymphocytes from Alzheimer’s Disease Patients
- (2019) Cosín-Tomàs et al. Nutrients
- Monozygotic twins and triplets discordant for amyotrophic lateral sclerosis display differential methylation and gene expression
- (2019) Ingrid S. Tarr et al. Scientific Reports
- Environmental exposure to polybrominated biphenyl (PBB) associates with an increased rate of biological aging
- (2019) Sarah W. Curtis et al. Aging-US
- The Alzheimer's Disease Exposome
- (2019) Caleb E. Finch et al. Alzheimers & Dementia
- Differential expression of microRNAs in Alzheimer's disease brain, blood, and cerebrospinal fluid
- (2019) Petros Takousis et al. Alzheimers & Dementia
- Paternal benzo[a]pyrene exposure alters the sperm DNA methylation levels of imprinting genes in F0 generation mice and their unexposed F1-2 male offspring
- (2019) Wenping Zhang et al. CHEMOSPHERE
- Genomic DNA methylation signatures in different tissues after ambient air particulate matter exposure
- (2019) Zhigang Li et al. ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
- Early impairment of epigenetic pattern in neurodegeneration: Additional mechanisms behind pyrethroid toxicity
- (2019) Laura Bordoni et al. EXPERIMENTAL GERONTOLOGY
- Gene-by-environment interactions in Alzheimer’s disease and Parkinson’s disease
- (2019) Amy R. Dunn et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- Particulate matter exposure shapes DNA methylation through the lifespan
- (2019) L. Ferrari et al. Clinical Epigenetics
- Peripheral blood DNA methylation differences in twin pairs discordant for Alzheimer’s disease
- (2019) Mikko Konki et al. Clinical Epigenetics
- Pharmacological Inhibition of G9a/GLP restores cognition and reduces oxidative stress, neuroinflammation and β-Amyloid plaques in an early-onset Alzheimer’s disease mouse model
- (2019) Christian Griñán-Ferré et al. Aging-US
- Vitamin D deficiency as a risk factor for dementia and Alzheimer’s disease: an updated meta-analysis
- (2019) Bingyan Chai et al. BMC Neurology
- Genetic and epigenetic study of an Alzheimer’s disease family with monozygotic triplets
- (2019) Ming Zhang et al. BRAIN
- Physical Activity, APOE Genotype, and Cognitive Decline: Exploring Gene-Environment Interactions in the UK Biobank
- (2019) Stephanie Folley et al. JOURNAL OF ALZHEIMERS DISEASE
- Traumatic brain injury (TBI) in collision sports: Possible mechanisms of transformation into chronic traumatic encephalopathy (CTE)
- (2019) Theodore B. VanItallie METABOLISM-CLINICAL AND EXPERIMENTAL
- Alcohol metabolism contributes to brain histone acetylation
- (2019) P. Mews et al. NATURE
- The Effects of Gene-Environment Interactions Between Cadmium Exposure and Apolipoprotein E4 on Memory in a Mouse Model of Alzheimer’s Disease
- (2019) Liang Zhang et al. TOXICOLOGICAL SCIENCES
- Dietary intakes and biomarker patterns of folate, vitamin B6, and vitamin B12 can be associated with cognitive impairment by hypermethylation of redox-related genes NUDT15 and TXNRD1
- (2019) Yu An et al. Clinical Epigenetics
- Alzheimer’s disease-associated (hydroxy)methylomic changes in the brain and blood
- (2019) Roy Lardenoije et al. Clinical Epigenetics
- Epigenetic signatures of smoking associate with cognitive function, brain structure, and mental and physical health outcomes in the Lothian Birth Cohort 1936
- (2019) Janie Corley et al. Translational Psychiatry
- Coffee intake and decreased amyloid pathology in human brain
- (2019) Jee Wook Kim et al. Translational Psychiatry
- Could Lifetime Lead Exposure Play a Role in Limbic-predominant Age-related TDP-43 Encephalopathy (LATE)?
- (2019) Esme Fuller-Thomson et al. JOURNAL OF ALZHEIMERS DISEASE
- A Review of the Brain-Gut-Microbiome Axis and the Potential Role of Microbiota in Alzheimer’s Disease
- (2019) Miao Sun et al. JOURNAL OF ALZHEIMERS DISEASE
- Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology
- (2018) Rebecca G. Smith et al. Alzheimers & Dementia
- Environmental Influences on the Epigenome: Exposure- Associated DNA Methylation in Human Populations
- (2018) Elizabeth M. Martin et al. Annual Review of Public Health
- Epigenetic modification of Nrf2 by sulforaphane increases the antioxidative and anti-inflammatory capacity in a cellular model of Alzheimer's disease
- (2018) Fangfang Zhao et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Altered microRNA, mRNA, and Protein Expression of Neurodegeneration-Related Biomarkers and Their Transcriptional and Epigenetic Modifiers in a Human Tau Transgenic Mouse Model in Response to Developmental Lead Exposure
- (2018) Anwar M. Masoud et al. JOURNAL OF ALZHEIMERS DISEASE
- Airborne Particulate Matter
- (2018) Jonathan E. Thompson JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
- DNA methylation-based biomarkers and the epigenetic clock theory of ageing
- (2018) Steve Horvath et al. NATURE REVIEWS GENETICS
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- (2018) Andrew P. Feinberg NEW ENGLAND JOURNAL OF MEDICINE
- APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction
- (2018) Jason A. Brandon et al. Frontiers in Aging Neuroscience
- Epigenome-wide analysis in newborn blood spots from monozygotic twins discordant for cerebral palsy reveals consistent regional differences in DNA methylation
- (2018) Namitha Mohandas et al. Clinical Epigenetics
- GWAS on family history of Alzheimer’s disease
- (2018) Riccardo E. Marioni et al. Translational Psychiatry
- Dietary Supplementation with S-Adenosyl Methionine Delayed Amyloid-β and Tau Pathology in 3xTg-AD Mice
- (2018) Sangmook Lee et al. JOURNAL OF ALZHEIMERS DISEASE
- Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation
- (2018) Joshua C. Bis et al. MOLECULAR PSYCHIATRY
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- (2018) Theodore A Slotkin et al. TOXICOLOGICAL SCIENCES
- DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex
- (2018) Gilles Gasparoni et al. Epigenetics & Chromatin
- Are noise and air pollution related to the incidence of dementia? A cohort study in London, England
- (2018) Iain M Carey et al. BMJ Open
- Increased DNA methylation variability in rheumatoid arthritis-discordant monozygotic twins
- (2018) Amy P. Webster et al. Genome Medicine
- Exposure to Environmental and Occupational Particulate Air Pollution as a Potential Contributor to Neurodegeneration and Diabetes: A Systematic Review of Epidemiological Research
- (2018) Eirini Dimakakou et al. International Journal of Environmental Research and Public Health
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- (2018) Isabel Alvarado-Cruz et al. Annals of Global Health
- Novel upregulation of amyloid-β precursor protein (APP) by microRNA-346 via targeting of APP mRNA 5′-untranslated region: Implications in Alzheimer’s disease
- (2018) Justin M. Long et al. MOLECULAR PSYCHIATRY
- Epigenome-wide study uncovers large-scale changes in histone acetylation driven by tau pathology in aging and Alzheimer’s human brains
- (2018) Hans-Ulrich Klein et al. NATURE NEUROSCIENCE
- A histone acetylome-wide association study of Alzheimer’s disease identifies disease-associated H3K27ac differences in the entorhinal cortex
- (2018) Sarah J. Marzi et al. NATURE NEUROSCIENCE
- Relationship between long non-coding RNAs and Alzheimer’s disease: a systematic review
- (2018) Lijuan Chen et al. PATHOLOGY RESEARCH AND PRACTICE
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- (2017) Claudio D’Addario et al. JOURNAL OF THE NEUROLOGICAL SCIENCES
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- (2017) Gill Livingston et al. LANCET
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- (2017) Hong Chen et al. LANCET
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- (2017) Anna K. Engstrom et al. Molecular Neurodegeneration
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- (2017) Ki-Hyun Kim et al. SCIENCE OF THE TOTAL ENVIRONMENT
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- (2017) Cecilia Wallin et al. Scientific Reports
- Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study
- (2017) Anya Topiwala et al. BMJ-British Medical Journal
- Moderate alcohol consumption as risk factor for adverse brain outcomes and cognitive decline: longitudinal cohort study
- (2017) Anya Topiwala et al. BMJ-British Medical Journal
- Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models
- (2017) M Cacciottolo et al. Translational Psychiatry
- S-Adenosylmethionine Mediates Glutathione Efficacy by Increasing Glutathione S-Transferase Activity: Implications for S-Adenosyl Methionine as A Neuroprotective Dietary Supplement
- (2017) Flaubert Tchantchou et al. JOURNAL OF ALZHEIMERS DISEASE
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- (2017) Amy Chan et al. JOURNAL OF ALZHEIMERS DISEASE
- Molecular genetics of early-onset Alzheimer's disease revisited
- (2016) Rita Cacace et al. Alzheimers & Dementia
- DNA Methylation in Newborns and Maternal Smoking in Pregnancy: Genome-wide Consortium Meta-analysis
- (2016) Bonnie R. Joubert et al. AMERICAN JOURNAL OF HUMAN GENETICS
- The Association Between Alcohol Use and the Progression of Alzheimer's Disease
- (2016) Devorah Heymann et al. Current Alzheimer Research
- Heavy metals (Pb, Cd, As and MeHg) as risk factors for cognitive dysfunction: A general review of metal mixture mechanism in brain
- (2016) Venkatanaidu Karri et al. ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY
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- (2016) Enzo Grossi et al. JOURNAL OF ALZHEIMERS DISEASE
- Early-Life Exposure to Lead (Pb) Alters the Expression of microRNA that Target Proteins Associated with Alzheimer’s Disease
- (2016) Anwar M. Masoud et al. JOURNAL OF ALZHEIMERS DISEASE
- Hypomethylation within gene promoter regions and type 1 diabetes in discordant monozygotic twins
- (2016) Emon Elboudwarej et al. JOURNAL OF AUTOIMMUNITY
- H3K9me3 Inhibition Improves Memory, Promotes Spine Formation, and Increases BDNF Levels in the Aged Hippocampus
- (2016) S. Snigdha et al. JOURNAL OF NEUROSCIENCE
- The Aging Epigenome
- (2016) Lauren N. Booth et al. MOLECULAR CELL
- A DNA methylation biomarker of alcohol consumption
- (2016) C Liu et al. MOLECULAR PSYCHIATRY
- APOEε4 and the associations of seafood and long-chain omega-3 fatty acids with cognitive decline
- (2016) Ondine van de Rest et al. NEUROLOGY
- Chronic exposure to aluminum and risk of Alzheimer’s disease: A meta-analysis
- (2016) Zengjin Wang et al. NEUROSCIENCE LETTERS
- Developmental exposure to lead (Pb) alters the expression of the human tau gene and its products in a transgenic animal model
- (2016) M. Dash et al. NEUROTOXICOLOGY
- Low levels of aluminum can lead to behavioral and morphological changes associated with Alzheimer's disease and age-related neurodegeneration
- (2016) Stephen C. Bondy NEUROTOXICOLOGY
- Exposure to air pollution as a potential contributor to cognitive function, cognitive decline, brain imaging, and dementia: A systematic review of epidemiologic research
- (2016) Melinda C. Power et al. NEUROTOXICOLOGY
- Transgenerational latent early-life associated regulation unites environment and genetics across generations
- (2016) Debomoy K Lahiri et al. Epigenomics
- The role of epigenetics in genetic and environmental epidemiology
- (2016) Christine Ladd-Acosta et al. Epigenomics
- Genetic and environmental influences interact with age and sex in shaping the human methylome
- (2016) Jenny van Dongen et al. Nature Communications
- CHRNA7 Polymorphisms and Dementia Risk: Interactions with Apolipoprotein ε4 and Cigarette Smoking
- (2016) Pei-Hsuan Weng et al. Scientific Reports
- Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer’s disease
- (2016) Corey T. Watson et al. Genome Medicine
- The Impact of External Factors on the Epigenome:In Uteroand over Lifetime
- (2016) Estela G. Toraño et al. Biomed Research International
- Environmental risk factors for dementia: a systematic review
- (2016) Lewis O. J. Killin et al. BMC Geriatrics
- Rescue of Early bace-1 and Global DNA Demethylation by S-Adenosylmethionine Reduces Amyloid Pathology and Improves Cognition in an Alzheimer’s Model
- (2016) Sonia Do Carmo et al. Scientific Reports
- Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning
- (2015) Morgan E Levine et al. Aging-US
- MicroRNA-214 participates in the neuroprotective effect of Resveratrol via inhibiting α-synuclein expression in MPTP-induced Parkinson’s disease mouse
- (2015) Zhao-Hui Wang et al. BIOMEDICINE & PHARMACOTHERAPY
- Common polygenic variation enhances risk prediction for Alzheimer’s disease
- (2015) Valentina Escott-Price et al. BRAIN
- Lead Exposure during Early Human Development and DNA Methylation of Imprinted Gene Regulatory Elements in Adulthood
- (2015) Yue Li et al. ENVIRONMENTAL HEALTH PERSPECTIVES
- Epigenetic effects of selenium and their implications for health
- (2015) Bodo Speckmann et al. Epigenetics
- The role dietary of bioactive compounds on the regulation of histone acetylases and deacetylases: A review
- (2015) F. Vahid et al. GENE
- The Relationship Between Cognitive Impairment and Global DNA Methylation Decrease Among Aluminum Potroom Workers
- (2015) Xiaojuan Yang et al. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
- Occupational Exposure to Aluminum and Alzheimer Disease
- (2015) Sohaib A. Virk et al. JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE
- Molecular insights into transgenerational non-genetic inheritance of acquired behaviours
- (2015) Johannes Bohacek et al. NATURE REVIEWS GENETICS
- Environmentally induced epigenetic transgenerational inheritance of disease susceptibility
- (2015) Eric E. Nilsson et al. Translational Research
- Environmental pollutants as risk factors for neurodegenerative disorders: Alzheimer and Parkinson diseases
- (2015) Miguel Chin-Chan et al. Frontiers in Cellular Neuroscience
- Can education rescue genetic liability for cognitive decline?
- (2015) C. Justin Cook et al. SOCIAL SCIENCE & MEDICINE
- Environmental chemicals and DNA methylation in adults: a systematic review of the epidemiologic evidence
- (2015) Adrian Ruiz-Hernandez et al. Clinical Epigenetics
- Smoking Is Associated with an Increased Risk of Dementia: A Meta-Analysis of Prospective Cohort Studies with Investigation of Potential Effect Modifiers
- (2015) Guochao Zhong et al. PLoS One
- Genome-wide hydroxymethylcytosine pattern changes in response to oxidative stress
- (2015) Benjamin Delatte et al. Scientific Reports
- Smoking and increased Alzheimer's disease risk: A review of potential mechanisms
- (2014) Timothy C. Durazzo et al. Alzheimers & Dementia
- GeMes, Clusters of DNA Methylation under Genetic Control, Can Inform Genetic and Epigenetic Analysis of Disease
- (2014) Yun Liu et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Genotoxic and epigenetic mechanisms in arsenic carcinogenicity
- (2014) Elisa Bustaffa et al. ARCHIVES OF TOXICOLOGY
- Systematic review of potential health risks posed by pharmaceutical, occupational and consumer exposures to metallic and nanoscale aluminum, aluminum oxides, aluminum hydroxide and its soluble salts
- (2014) Calvin C. Willhite et al. CRITICAL REVIEWS IN TOXICOLOGY
- Alzheimer’s Disease and Environmental Exposure to Lead: The Epidemiologic Evidence and Potential Role of Epigenetics
- (2014) Kelly M. Bakulski et al. Current Alzheimer Research
- Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease
- (2014) Katie Lunnon et al. NATURE NEUROSCIENCE
- Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci
- (2014) Philip L De Jager et al. NATURE NEUROSCIENCE
- Implication of sperm RNAs in transgenerational inheritance of the effects of early trauma in mice
- (2014) Katharina Gapp et al. NATURE NEUROSCIENCE
- Exposure to As-, Cd-, and Pb-Mixture Induces Aβ, Amyloidogenic APP Processing and Cognitive Impairments via Oxidative Stress-Dependent Neuroinflammation in Young Rats
- (2014) Anushruti Ashok et al. TOXICOLOGICAL SCIENCES
- Epigenetics of discordant monozygotic twins: implications for disease
- (2014) Juan E Castillo-Fernandez et al. Genome Medicine
- Elevated Serum Pesticide Levels and Risk for Alzheimer Disease
- (2014) Jason R. Richardson et al. JAMA Neurology
- Epigenetic regulation of the neural transcriptome and alcohol interference during development
- (2014) Marisol Resendiz et al. Frontiers in Genetics
- Role of early life exposure and environment on neurodegeneration: implications on brain disorders
- (2014) Shweta Modgil et al. Translational Neurodegeneration
- DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial
- (2013) Welma Stonehouse et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Resveratrol improves learning and memory in normally aged mice through microRNA-CREB pathway
- (2013) Yong-Na Zhao et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Non-coding RNAs as direct and indirect modulators of epigenetic regulation
- (2013) Veronica J Peschansky et al. Epigenetics
- Epigenetic effects of natural polyphenols: A focus on SIRT1-mediated mechanisms
- (2013) Vincent B. Owona Ayissi et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Parental olfactory experience influences behavior and neural structure in subsequent generations
- (2013) Brian G Dias et al. NATURE NEUROSCIENCE
- Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients
- (2013) Leonidas Chouliaras et al. NEUROBIOLOGY OF AGING
- Genome-Wide Alteration of Histone H3K9 Acetylation Pattern in Mouse Offspring Prenatally Exposed to Arsenic
- (2013) Andrea A. Cronican et al. PLoS One
- Epigenetics and pesticides
- (2013) M. Collotta et al. TOXICOLOGY
- Changes in methylation patterns of multiple genes from peripheral blood leucocytes of Alzheimer's disease patients
- (2012) Yaping Hou et al. ACTA NEUROPSYCHIATRICA
- Associations between Arsenic Exposure and Global Posttranslational Histone Modifications among Adults in Bangladesh
- (2012) Y. Chervona et al. CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION
- Threshold-Independent Meta-Analysis of Alzheimer`s Disease Transcriptomes shows Progressive Changes in Hippocampal Functions, Epigenetics and microRNA Regulation
- (2012) Shahar Barbash et al. Current Alzheimer Research
- Epigenetic Effects of Environmental Chemicals Bisphenol A and Phthalates
- (2012) Sher Singh et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Epigenetics and the environment: emerging patterns and implications
- (2012) Robert Feil et al. NATURE REVIEWS GENETICS
- Functions of DNA methylation: islands, start sites, gene bodies and beyond
- (2012) Peter A. Jones NATURE REVIEWS GENETICS
- S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice
- (2012) Andrea Fuso et al. NEUROBIOLOGY OF AGING
- APOE and neuroenergetics: an emerging paradigm in Alzheimer's disease
- (2012) Andrew B. Wolf et al. NEUROBIOLOGY OF AGING
- Oxidative stress induces DNA demethylation and histone acetylation in SH-SY5Y cells: potential epigenetic mechanisms in gene transcription in Aβ production
- (2012) Xinling Gu et al. NEUROBIOLOGY OF AGING
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Resveratrol prevents nicotine-induced teratogenesis in cultured mouse embryos
- (2012) Chunmei Lin et al. REPRODUCTIVE TOXICOLOGY
- Blood chromatin as a biosensor of the epigenetic milieu: a tool for studies in living psychiatric patients
- (2012) Rajiv P Sharma Epigenomics
- Gene × environment interaction by a longitudinal epigenome-wide association study (LEWAS) overcomes limitations of genome-wide association study (GWAS)
- (2012) Debomoy K Lahiri et al. Epigenomics
- Regulation of chromatin by histone modifications
- (2011) Andrew J Bannister et al. CELL RESEARCH
- Dietary Omega 3 Polyunsaturated Fatty Acids and Alzheimers Disease: Interaction with Apolipoprotein E Genotype
- (2011) P. Barberger-Gateau et al. Current Alzheimer Research
- Perinatal undernutrition affects the methylation and expression of the leptin gene in adults: implication for the understanding of metabolic syndrome
- (2011) Céline Jousse et al. FASEB JOURNAL
- Stabilization of Suv39H1 by SirT1 Is Part of Oxidative Stress Response and Ensures Genome Protection
- (2011) Laia Bosch-Presegué et al. MOLECULAR CELL
- APOE and Alzheimer disease: a major gene with semi-dominant inheritance
- (2011) E Genin et al. MOLECULAR PSYCHIATRY
- The Redox Basis of Epigenetic Modifications: From Mechanisms to Functional Consequences
- (2010) Anthony R. Cyr et al. ANTIOXIDANTS & REDOX SIGNALING
- One-Carbon Metabolism and Alzheimers Disease: Focus on Epigenetics
- (2010) Fabio Coppede CURRENT GENOMICS
- DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models☆☆☆
- (2010) Andrea Fuso et al. JOURNAL OF NUTRITIONAL BIOCHEMISTRY
- The Dutch Hunger Winter and the developmental origins of health and disease
- (2010) L. C. Schulz PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Epigenetics, oxidative stress, and Alzheimer disease
- (2009) Nasser H. Zawia et al. FREE RADICAL BIOLOGY AND MEDICINE
- DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific
- (2009) Elmar W. Tobi et al. HUMAN MOLECULAR GENETICS
- The effect of alcohol and tobacco consumption, and apolipoprotein E genotype, on the age of onset in Alzheimer's disease
- (2009) Dylan G. Harwood et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Dietary deficiency increases presenilin expression, gamma-secretase activity, and Abeta levels: potentiation by ApoE genotype and alleviation byS-adenosyl methionine
- (2009) Amy Chan et al. JOURNAL OF NEUROCHEMISTRY
- The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases
- (2009) D K Lahiri et al. MOLECULAR PSYCHIATRY
- Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
- (2009) Jean-Charles Lambert et al. NATURE GENETICS
- Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
- (2009) Denise Harold et al. NATURE GENETICS
- Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency
- (2009) Andrea Fuso et al. NEUROBIOLOGY OF AGING
- FE65 Binds Teashirt, Inhibiting Expression of the Primate-Specific Caspase-4
- (2009) Yuji Kajiwara et al. PLoS One
- Epigenetic Differences in Cortical Neurons from a Pair of Monozygotic Twins Discordant for Alzheimer's Disease
- (2009) Diego Mastroeni et al. PLoS One
- Alzheimer's Disease (AD)-Like Pathology in Aged Monkeys after Infantile Exposure to Environmental Metal Lead (Pb): Evidence for a Developmental Origin and Environmental Link for AD
- (2008) J. Wu et al. JOURNAL OF NEUROSCIENCE
- Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases
- (2008) Lucia Migliore et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Environmental-induced oxidative stress in neurodegenerative disorders and aging
- (2008) Lucia Migliore et al. MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS
- Long-term Air Pollution Exposure Is Associated with Neuroinflammation, an Altered Innate Immune Response, Disruption of the Blood-Brain Barrier, Ultrafine Particulate Deposition, and Accumulation of Amyloid β-42 and α-Synuclein in Children and Young Adults
- (2008) Lilian Calderón-Garcidueñas et al. TOXICOLOGIC PATHOLOGY
- The association of APOE genotype and cognitive decline in interaction with risk factors in a 65–69 year old community sample
- (2008) Helen Christensen et al. BMC Geriatrics
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