A Meta-Analysis of Brain DNA Methylation Across Sex, Age, and Alzheimer's Disease Points for Accelerated Epigenetic Aging in Neurodegeneration

The lipid elongation enzyme ELOVL2 is a molecular regulator of aging in the retina

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Impaired lipid metabolism by age-dependent DNA methylation alterations accelerates aging

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Early epigenetic changes of Alzheimer’s disease in the human hippocampus

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Epigenome-wide association study of Alzheimer’s disease replicates 22 differentially methylated positions and 30 differentially methylated regions

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Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

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Integrated DNA methylation and gene expression profiling across multiple brain regions implicate novel genes in Alzheimer’s disease

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Sex-differential DNA methylation and associated regulation networks in human brain implicated in the sex-biased risks of psychiatric disorders

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Epigenetic signatures of Werner syndrome occur early in life and are distinct from normal epigenetic aging processes

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Human aging DNA methylation signatures are conserved but accelerated in cultured fibroblasts

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NEAT1 is overexpressed in Parkinson’s disease substantia nigra and confers drug-inducible neuroprotection from oxidative stress

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Alzheimer’s Disease Associated Genes Ankyrin and Tau Cause Shortened Lifespan and Memory Loss in Drosophila

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DNA methylation signature of human hippocampus in Alzheimer’s disease is linked to neurogenesis

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Sex Differences in the Epigenome: A Cause or Consequence of Sexual Differentiation of the Brain?

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Tobacco smoking induces changes in true DNA methylation, hydroxymethylation and gene expression in bronchoalveolar lavage cells

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Maternal exposures to persistent organic pollutants are associated with DNA methylation of thyroid hormone-related genes in placenta differently by infant sex

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Estrogens counteract the profibrotic effects of TGF-β and their inhibition exacerbates experimental dermal fibrosis

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Novel age-associated DNA methylation changes and epigenetic age acceleration in middle-aged African Americans and whites

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Assessment of Bones Deficient in Fibrillin-1 Microfibrils Reveals Pronounced Sex Differences

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Hearing loss is an early biomarker in APP/PS1 Alzheimer’s disease mice

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Adult onset of type 3 deiodinase deficiency in mice alters brain gene expression and increases locomotor activity

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An epigenome-wide association study of sex-specific chronological ageing

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Elevated DNA methylation across a 48-kb region spanning the HOXA gene cluster is associated with Alzheimer's disease neuropathology

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Genome-wide association study identified ATP6V1H locus influencing cerebrospinal fluid BACE activity

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Multiple Layers of CDK5R1 Regulation in Alzheimer’s Disease Implicate Long Non-Coding RNAs

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Hypermethylation of TRIM59 and KLF14 Influences Cell Death Signaling in Familial Alzheimer’s Disease

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Loss of the Drosophila m-AAA mitochondrial protease paraplegin results in mitochondrial dysfunction, shortened lifespan, and neuronal and muscular degeneration

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Age-related DNA methylation changes are tissue-specific with ELOVL2 promoter methylation as exception

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Loss of MeCP2 in adult 5-HT neurons induces 5-HT1A autoreceptors, with opposite sex-dependent anxiety and depression phenotypes

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X chromosome dosage and presence of SRY shape sex-specific differences in DNA methylation at an autosomal region in human cells

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DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex

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Alzheimer's disease DNA methylome of pyramidal layers in frontal cortex: laser-assisted microdissection study

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Accelerated DNA methylation changes in middle-aged men define sexual dimorphism in human lifespans

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MicroRNA and Long Non-coding RNA Regulation in Skeletal Muscle From Growth to Old Age Shows Striking Dysregulation of the Callipyge Locus

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A reverse genetics cell-based evaluation of genes linked to healthy human tissue age

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Reduced acoustic startle response and peripheral hearing loss in the 5xFAD mouse model of Alzheimer's disease

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DNA methylation in ELOVL2 and C1orf132 correctly predicted chronological age of individuals from three disease groups

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Single-Base Resolution Mapping of 5-Hydroxymethylcytosine Modifications in Hippocampus of Alzheimer’s Disease Subjects

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ANK1 is up-regulated in laser captured microglia in Alzheimer’s brain; the importance of addressing cellular heterogeneity

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Embryonic loss of human females with partial trisomy 19 identifies region critical for the single active X

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Whole Genome Expression Analysis in a Mouse Model of Tauopathy Identifies MECP2 as a Possible Regulator of Tau Pathology

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Sex differences in DNA methylation of the cord blood are related to sex-bias psychiatric diseases

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Aging-associated DNA methylation changes in middle-aged individuals: the Young Finns study

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Systemic Age-Associated DNA Hypermethylation ofELOVL2Gene: In Vivo and In Vitro Evidences of a Cell Replication Process

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Gain-of-function mutations in protein kinase Cα (PKCα) may promote synaptic defects in Alzheimer’s disease

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Blood-based biomarkers of age-associated epigenetic changes in human islets associate with insulin secretion and diabetes

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The cerebellum ages slowly according to the epigenetic clock

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Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning

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