CpG and non-CpG Presenilin1 methylation pattern in course of neurodevelopment and neurodegeneration is associated with gene expression in human and murine brain

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

(2019) Adam R. Smith et al.   Clinical Epigenetics

DNA methylation variability in Alzheimer's disease

(2018) Zhiguang Huo et al.   NEUROBIOLOGY OF AGING

Methylation profiles in peripheral blood CD4+ lymphocytes versus brain: The relation to Alzheimer's disease pathology

(2016) Lei Yu et al.   Alzheimers & Dementia

Altered Mitochondrial DNA Methylation Pattern in Alzheimer Disease–Related Pathology and in Parkinson Disease

(2016) Marta Blanch et al.   AMERICAN JOURNAL OF PATHOLOGY

Artificial Neural Networks Link One-Carbon Metabolism to Gene-Promoter Methylation in Alzheimer’s Disease

(2016) Enzo Grossi et al.   JOURNAL OF ALZHEIMERS DISEASE

Sexually Dimorphic Expression of Reelin in the Brain of a Mouse Model of Alzheimer Disease

(2016) Giampiero Palladino et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Promoter-Specific Hypomethylation Correlates with IL-1β Overexpression in Tuberous Sclerosis Complex (TSC)

(2016) A. Fuso et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Quantitative comparison of DNA methylation assays for biomarker development and clinical applications

(2016) Christoph Bock et al.   NATURE BIOTECHNOLOGY

Epigenetic regulation of presenilin 1 and 2 in the cerebral cortex of mice during development

(2015) Ashish Kumar et al.   Developmental Neurobiology

Environment, epigenetics and neurodegeneration: Focus on nutrition in Alzheimer's disease

(2015) Vincenzina Nicolia et al.   EXPERIMENTAL GERONTOLOGY

Neuroinflammatory Signals in Alzheimer Disease and APP/PS1 Transgenic Mice

(2015) Irene López-González et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Folic acid administration inhibits amyloid β-peptide accumulation in APP/PS1 transgenic mice

(2015) Wen Li et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Peripheral leukocyte expression of the potential biomarker proteins Bdnf, Sirt1, and Psen1 is not regulated by promoter methylation in Alzheimer's disease patients

(2015) Lucia Carboni et al.   NEUROSCIENCE LETTERS

Methylation analysis of multiple genes in blood DNA of Alzheimer’s disease and healthy individuals

(2015) Pierpaola Tannorella et al.   NEUROSCIENCE LETTERS

The epigenetics of aging and neurodegeneration

(2015) Roy Lardenoije et al.   PROGRESS IN NEUROBIOLOGY

Epigenetic Alterations in Alzheimer’s Disease

(2015) Jose V. Sanchez-Mut et al.   Frontiers in Behavioral Neuroscience

Disclosing Bias in Bisulfite Assay: MethPrimers Underestimate High DNA Methylation

(2015) Andrea Fuso et al.   PLoS One

PSEN1 Promoter Demethylation in Hyperhomocysteinemic TgCRND8 Mice is the Culprit, not the Consequence

(2014) Andrea Fuso et al.   Current Alzheimer Research

The evidence for functional non-CpG methylation in mammalian cells

(2014) Vibha Patil et al.   Epigenetics

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

(2014) Katie Lunnon et al.   NATURE NEUROSCIENCE

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

(2014) Philip L De Jager et al.   NATURE NEUROSCIENCE

A fast growing spectrum of biological functions of γ-secretase in development and disease

(2013) Nathalie Jurisch-Yaksi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES

Distribution, recognition and regulation of non-CpG methylation in the adult mammalian brain

(2013) Junjie U Guo et al.   NATURE NEUROSCIENCE

Differences in DNA methylation between human neuronal and glial cells are concentrated in enhancers and non-CpG sites

(2013) Alexey Kozlenkov et al.   NUCLEIC ACIDS RESEARCH

Global Epigenomic Reconfiguration During Mammalian Brain Development

(2013) R. Lister et al.   SCIENCE

The Amyloid Precursor Protein (APP) Family Members are Key Players in S-adenosylmethionine Formation by MAT2A and ModifyBACE1andPSEN1Gene Expression-Relevance for Alzheimer's Disease

(2012) Andreas Schrötter et al.   MOLECULAR & CELLULAR PROTEOMICS

S-adenosylmethionine reduces the progress of the Alzheimer-like features induced by B-vitamin deficiency in mice

(2012) Andrea Fuso et al.   NEUROBIOLOGY OF AGING

Non-CpG Methylation Occurs in the Regulatory Region of the Sry Gene

(2011) Koichiro NISHINO et al.   JOURNAL OF REPRODUCTION AND DEVELOPMENT

One-carbon metabolism and Alzheimer's disease: is it all a methylation matter?

(2011) Andrea Fuso et al.   NEUROBIOLOGY OF AGING

Epigenetic mechanisms in Alzheimer's disease

(2011) Diego Mastroeni et al.   NEUROBIOLOGY OF AGING

Genomic Distribution and Inter-Sample Variation of Non-CpG Methylation across Human Cell Types

(2011) Michael J. Ziller et al.   PLoS Genetics

Early demethylation of non-CpG, CpC-rich, elements in the myogenin 5’-flanking region

(2010) Andrea Fuso et al.   CELL CYCLE

Subcellular TSC22D4 Localization in Cerebellum Granule Neurons of the Mouse Depends on Development and Differentiation

(2010) Sonia Canterini et al.   CEREBELLUM

DNA methylase and demethylase activities are modulated by one-carbon metabolism in Alzheimer's disease models☆☆☆

(2010) Andrea Fuso et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

DNA Methylation of Alzheimer Disease and Tauopathy-Related Genes in Postmortem Brain

(2009) Marta Barrachina et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Changes in Presenilin 1 gene methylation pattern in diet-induced B vitamin deficiency

(2009) Andrea Fuso et al.   NEUROBIOLOGY OF AGING

S-Adenosylhomocysteine increases β-amyloid formation in BV-2 microglial cells by increased expressions of β-amyloid precursor protein and presenilin 1 and by hypomethylation of these gene promoters

(2009) Hung-Chi Lin et al.   NEUROTOXICOLOGY

Activity of γ -Secretase on Substrates Other than APP

(2008) Alberto D.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Notch: from neural development to neurological disorders

(2008) Justin D. Lathia et al.   JOURNAL OF NEUROCHEMISTRY

B-vitamin deprivation induces hyperhomocysteinemia and brain S-adenosylhomocysteine, depletes brain S-adenosylmethionine, and enhances PS1 and BACE expression and amyloid-β deposition in mice

(2008) Andrea Fuso et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases

(2008) Lucia Migliore et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Age-Specific Epigenetic Drift in Late-Onset Alzheimer's Disease

(2008) Sun-Chong Wang et al.   PLoS One

Presenilin: RIP and beyond

(2008) Matthew R. Hass et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY