Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
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Title
Common variants in Alzheimer’s disease and risk stratification by polygenic risk scores
Authors
Keywords
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Journal
Nature Communications
Volume 12, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-06-07
DOI
10.1038/s41467-021-22491-8
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Note: Only part of the references are listed.- Risk prediction of late-onset Alzheimer’s disease implies an oligogenic architecture
- (2020) Qian Zhang et al. Nature Communications
- Genome-wide meta-analysis identifies new loci and functional pathways influencing Alzheimer’s disease risk
- (2019) Iris E. Jansen et al. NATURE GENETICS
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
- (2019) Brian W. Kunkle et al. NATURE GENETICS
- Do BACE inhibitor failures in Alzheimer’s patients challenge the amyloid hypothesis of the disease?
- (2019) Francesco Panza et al. Expert Review of Neurotherapeutics
- A rare functional variant of SHARPIN attenuates the inflammatory response and associates with increased risk of late-onset Alzheimer’s disease
- (2019) Yuya Asanomi et al. MOLECULAR MEDICINE
- Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio
- (2018) Luke R. Lloyd-Jones et al. GENETICS
- The effect of APOE and other common genetic variants on the onset of Alzheimer's disease and dementia: a community-based cohort study
- (2018) Sven J van der Lee et al. LANCET NEUROLOGY
- Randomized Trial of Verubecestat for Mild-to-Moderate Alzheimer’s Disease
- (2018) Michael F. Egan et al. NEW ENGLAND JOURNAL OF MEDICINE
- One for all and all for One: Improving replication of genetic studies through network diffusion
- (2018) Daniel Lancour et al. PLoS Genetics
- Transformation of Summary Statistics from Linear Mixed Model Association on All-or-None Traits to Odds Ratio
- (2018) Luke R. Lloyd-Jones et al. GENETICS
- GWAS on family history of Alzheimer’s disease
- (2018) Riccardo E. Marioni et al. Translational Psychiatry
- Alzheimer's Prevention Initiative: A Plan to Accelerate the Evaluation of Presymptomatic Treatments
- (2018) Eric M. Reiman et al. JOURNAL OF ALZHEIMERS DISEASE
- Genome-wide polygenic scores for common diseases identify individuals with risk equivalent to monogenic mutations
- (2018) Amit V. Khera et al. NATURE GENETICS
- Implication of the APP Gene in Intellectual Abilities
- (2017) Craig Myrum et al. JOURNAL OF ALZHEIMERS DISEASE
- Case–control association mapping by proxy using family history of disease
- (2017) Jimmy Z Liu et al. NATURE GENETICS
- Functional mapping and annotation of genetic associations with FUMA
- (2017) Kyoko Watanabe et al. Nature Communications
- Genetic assessment of age-associated Alzheimer disease risk: Development and validation of a polygenic hazard score
- (2017) Rahul S. Desikan et al. PLOS MEDICINE
- APP as a Protective Factor in Acute Neuronal Insults
- (2017) Dimitri Hefter et al. Frontiers in Molecular Neuroscience
- Genome-wide significant risk factors for Alzheimer’s disease: role in progression to dementia due to Alzheimer's disease among subjects with mild cognitive impairment
- (2016) A Lacour et al. MOLECULAR PSYCHIATRY
- A reference panel of 64,976 haplotypes for genotype imputation
- (2016) NATURE GENETICS
- Genetic risk of neurodegenerative diseases is associated with mild cognitive impairment and conversion to dementia
- (2015) Hieab H.H. Adams et al. Alzheimers & Dementia
- A 22-single nucleotide polymorphism Alzheimer's disease risk score correlates with family history, onset age, and cerebrospinal fluid Aβ 42
- (2015) Kristel Sleegers et al. Alzheimers & Dementia
- A novel Alzheimer disease locus located near the gene encoding tau protein
- (2015) G Jun et al. MOLECULAR PSYCHIATRY
- A global reference for human genetic variation
- (2015) Richard A. Gibbs et al. NATURE
- LD Score regression distinguishes confounding from polygenicity in genome-wide association studies
- (2015) Brendan K Bulik-Sullivan et al. NATURE GENETICS
- UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age
- (2015) Cathie Sudlow et al. PLOS MEDICINE
- The Genotype-Tissue Expression (GTEx) project
- (2013) John Lonsdale et al. NATURE GENETICS
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Assessing the role of the TREM2 p.R47H variant as a risk factor for Alzheimer's disease and frontotemporal dementia
- (2013) Agustín Ruiz et al. NEUROBIOLOGY OF AGING
- Comprehensive Search for Alzheimer Disease Susceptibility Loci in the APOE Region
- (2012) Gyungah Jun et al. ARCHIVES OF NEUROLOGY
- Genetic risk score predicting accelerated progression from mild cognitive impairment to Alzheimer’s disease
- (2012) E. Rodríguez-Rodríguez et al. JOURNAL OF NEURAL TRANSMISSION
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
- (2012) Thorlakur Jonsson et al. NATURE
- Variant of TREM2 Associated with the Risk of Alzheimer's Disease
- (2012) Thorlakur Jonsson et al. NEW ENGLAND JOURNAL OF MEDICINE
- TREM2 Variants in Alzheimer's Disease
- (2012) Rita Guerreiro et al. NEW ENGLAND JOURNAL OF MEDICINE
- Wild type but not mutant APP is involved in protective adaptive responses against oxidants
- (2010) Giovanna Cenini et al. AMINO ACIDS
- METAL: fast and efficient meta-analysis of genomewide association scans
- (2010) C. J. Willer et al. BIOINFORMATICS
- Genome-wide Analysis of Genetic Loci Associated With Alzheimer Disease
- (2010) Sudha Seshadri JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
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