Alzheimer’s disease-associated (hydroxy)methylomic changes in the brain and blood

Parallel profiling of DNA methylation and hydroxymethylation highlights neuropathology-associated epigenetic variation in Alzheimer’s disease

(2019) Adam R. Smith et al.   Clinical Epigenetics

Transcriptome Changes in the Alzheimer’s Disease Middle Temporal Gyrus: Importance of RNA Metabolism and Mitochondria-Associated Membrane Genes

(2019) Ignazio S. Piras et al.   JOURNAL OF ALZHEIMERS DISEASE

Identifying mislabeled and contaminated DNA methylation microarray data: an extended quality control toolset with examples from GEO

(2018) Jonathan A. Heiss et al.   Clinical Epigenetics

DNA methylation analysis on purified neurons and glia dissects age and Alzheimer’s disease-specific changes in the human cortex

(2018) Gilles Gasparoni et al.   Epigenetics & Chromatin

Increased Transforming Growth Factor β2 in the Neocortex of Alzheimer’s Disease and Dementia with Lewy Bodies is Correlated with Disease Severity and Soluble Aβ42 Load

(2017) Joyce R. Chong et al.   JOURNAL OF ALZHEIMERS DISEASE

The 5-Hydroxymethylcytosine (5hmC) Reader UHRF2 Is Required for Normal Levels of 5hmC in Mouse Adult Brain and Spatial Learning and Memory

(2017) Ruoyu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Forced swimming-induced oxytocin release into blood and brain: Effects of adrenalectomy and corticosterone treatment

(2017) Luz Torner et al.   PSYCHONEUROENDOCRINOLOGY

NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies

(2017) Limin Song et al.   Frontiers in Cellular Neuroscience

Modulation of cognition and anxiety-like behavior by bone remodeling

(2017) Lori Khrimian et al.   Molecular Metabolism

Simple and accurate single base resolution analysis of 5-hydroxymethylcytosine by catalytic oxidative bisulfite sequencing using micelle incarcerated oxidants

(2016) Seketsu Fukuzawa et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Beyond Acetylcholinesterase Inhibitors: Novel Cholinergic Treatments for Alzheimer’s Disease

(2016) Asante Kamkwalala et al.   Current Alzheimer Research

Corrigendum to “Genome-wide association interaction analysis for Alzheimer's disease.” [Neurobiol. Aging 35 (2014) 2436–2443]

(2016) Elena S. Gusareva et al.   NEUROBIOLOGY OF AGING

Epigenetic modification ofOXTand human sociability

(2016) Brian W. Haas et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complement and microglia mediate early synapse loss in Alzheimer mouse models

(2016) S. Hong et al.   SCIENCE

Prediction of disease–gene–drug relationships following a differential network analysis

(2016) S Zickenrott et al.   Cell Death & Disease

Common DNA methylation alterations of Alzheimer’s disease and aging in peripheral whole blood

(2016) Hongdong Li et al.   Oncotarget

Genome-wide DNA methylation profiling in the superior temporal gyrus reveals epigenetic signatures associated with Alzheimer’s disease

(2016) Corey T. Watson et al.   Genome Medicine

Immunotherapies in Alzheimer’s disease: Too much, too little, too late or off-target?

(2015) Isabelle St-Amour et al.   ACTA NEUROPATHOLOGICA

Global changes in DNA methylation in Alzheimer’s disease peripheral blood mononuclear cells

(2015) Andrea Di Francesco et al.   BRAIN BEHAVIOR AND IMMUNITY

Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program

(2015) Thomas G. Beach et al.   NEUROPATHOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

The epigenetics of aging and neurodegeneration

(2015) Roy Lardenoije et al.   PROGRESS IN NEUROBIOLOGY

Distinctive RNA Expression Profiles in Blood Associated With Alzheimer Disease After Accounting for White Matter Hyperintensities

(2014) Zhouxian Bai et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Environmental enrichment modulates 5-hydroxymethylcytosine dynamics in hippocampus

(2014) Hasan Irier et al.   GENOMICS

C18 ORF1, a Novel Negative Regulator of Transforming Growth Factor-β Signaling

(2014) Naoko Nakano et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Methylomic profiling implicates cortical deregulation of ANK1 in Alzheimer's disease

(2014) Katie Lunnon et al.   NATURE NEUROSCIENCE

Alzheimer's disease: early alterations in brain DNA methylation at ANK1, BIN1, RHBDF2 and other loci

(2014) Philip L De Jager et al.   NATURE NEUROSCIENCE

The Evolution of Preclinical Alzheimer’s Disease: Implications for Prevention Trials

(2014) Reisa Sperling et al.   NEURON

New roles of the multidimensional adipokine: Chemerin

(2014) Syeda Sadia Fatima et al.   PEPTIDES

Amyloid-β induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer’s disease

(2014) M-S Tan et al.   Cell Death & Disease

The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy

(2013) Patrick L. McGeer et al.   ACTA NEUROPATHOLOGICA

Epigenetic studies in Alzheimer's disease: Current findings, caveats, and considerations for future studies

(2013) Katie Lunnon et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

A data-driven approach to preprocessing Illumina 450K methylation array data

(2013) Ruth Pidsley et al.   BMC GENOMICS

Discovery of cross-reactive probes and polymorphic CpGs in the Illumina Infinium HumanMethylation450 microarray

(2013) Yi-an Chen et al.   Epigenetics

Sex- and age-interacting eQTLs in human complex diseases

(2013) Chen Yao et al.   HUMAN MOLECULAR GENETICS

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

(2013) Leonidas Chouliaras et al.   NEUROBIOLOGY OF AGING

Global changes in DNA methylation and hydroxymethylation in Alzheimer's disease human brain

(2013) Natacha Coppieters et al.   NEUROBIOLOGY OF AGING

Microglial derived tumor necrosis factor-α drives Alzheimer's disease-related neuronal cell cycle events

(2013) Kiran Bhaskar et al.   NEUROBIOLOGY OF DISEASE

The role of oxytocin in social bonding, stress regulation and mental health: An update on the moderating effects of context and interindividual differences

(2013) Miranda Olff et al.   PSYCHONEUROENDOCRINOLOGY

Potential functional roles of DNA demethylation intermediates

(2013) Chun-Xiao Song et al.   TRENDS IN BIOCHEMICAL SCIENCES

The sva package for removing batch effects and other unwanted variation in high-throughput experiments

(2012) Jeffrey T. Leek et al.   BIOINFORMATICS

A small-molecule enhancer of autophagy decreases levels of Aβ and APP-CTF via Atg5-dependent autophagy pathway

(2011) Yuan Tian et al.   FASEB JOURNAL

Tissue type is a major modifier of the 5-hydroxymethylcytosine content of human genes

(2011) C. E. Nestor et al.   GENOME RESEARCH

Network medicine: a network-based approach to human disease

(2010) Albert-László Barabási et al.   NATURE REVIEWS GENETICS

Analysis of a t(18;21)(p11.1;p11.1) translocation in a family with schizophrenia

(2009) Joanne M A Meerabux et al.   JOURNAL OF HUMAN GENETICS

Genome-wide association study of blood pressure and hypertension

(2009) Daniel Levy et al.   NATURE GENETICS

A network view of disease and compound screening

(2009) Eric E. Schadt et al.   NATURE REVIEWS DRUG DISCOVERY

The Nuclear DNA Base 5-Hydroxymethylcytosine Is Present in Purkinje Neurons and the Brain

(2009) S. Kriaucionis et al.   SCIENCE

The CAP Superfamily: Cysteine-Rich Secretory Proteins, Antigen 5, and Pathogenesis-Related 1 Proteins—Roles in Reproduction, Cancer, and Immune Defense

(2008) Gerard M. Gibbs et al.   ENDOCRINE REVIEWS

Teneurins: Important regulators of neural circuitry

(2008) Timothy R. Young et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY