APOE Genotype and Alzheimer’s Disease: The Influence of Lifestyle and Environmental Factors
Published 2021 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
APOE Genotype and Alzheimer’s Disease: The Influence of Lifestyle and Environmental Factors
Authors
Keywords
-
Journal
ACS Chemical Neuroscience
Volume 12, Issue 15, Pages 2749-2764
Publisher
American Chemical Society (ACS)
Online
2021-07-19
DOI
10.1021/acschemneuro.1c00295
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- A Workshop on Cognitive Aging and Impairment in the 9/11-Exposed Population
- (2021) Robert D. Daniels et al. International Journal of Environmental Research and Public Health
- Low CD4 nadir exacerbates the impacts of APOE ε4 on functional connectivity and memory in adults with HIV
- (2021) Fan Nils Yang et al. AIDS
- Association Between Elevated Depressive Symptoms and Cognitive Function Moderated by APOE4 Status: Framingham Offspring Study
- (2021) Ryan J. Piers et al. JOURNAL OF ALZHEIMERS DISEASE
- Potential of Caffeine in Alzheimer’s Disease—A Review of Experimental Studies
- (2021) Piotr Londzin et al. Nutrients
- Interaction between APOE4 and herpes simplex virus type 1 in Alzheimer's disease
- (2020) Morgane Linard et al. Alzheimers & Dementia
- Physical activity as moderator of the association between APOE and cognitive decline in older adults: Results from three longitudinal cohort studies
- (2020) Najada Stringa et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Therapeutic approaches targeting Apolipoprotein E function in Alzheimer’s disease
- (2020) Tosha Williams et al. Molecular Neurodegeneration
- Low-Density Lipoprotein Cholesterol and Alzheimer's Disease: A Systematic Review and Meta-Analysis
- (2020) Zhike Zhou et al. Frontiers in Aging Neuroscience
- Midlife Lifestyle Activities Moderate APOE ε4 Effect on in vivo Alzheimer’s Disease Pathologies
- (2020) So Yeon Jeon et al. Frontiers in Aging Neuroscience
- Association of moderate alcohol intake with in vivo amyloid-beta deposition in human brain: A cross-sectional study
- (2020) Jee Wook Kim et al. PLOS MEDICINE
- Associations of Apolipoprotein E ε4 Genotype and Ball Heading With Verbal Memory in Amateur Soccer Players
- (2020) Liane E. Hunter et al. JAMA Neurology
- Influence of Western diet and APOE genotype on Alzheimer's disease risk
- (2020) P.M. Sullivan NEUROBIOLOGY OF DISEASE
- Molecular Insight into the Therapeutic Promise of Targeting APOE4 for Alzheimer’s Disease
- (2020) Abdullah Al Mamun et al. Oxidative Medicine and Cellular Longevity
- The relationship between physical activity, apolipoprotein E ε4 carriage, and brain health
- (2020) Jaisalmer de Frutos-Lucas et al. Alzheimers Research & Therapy
- The Influence of Physical Activity and Epigenomics On Cognitive Function and Brain Health in Breast Cancer
- (2020) Monica A. Wagner et al. Frontiers in Aging Neuroscience
- Is APOE ε4 associated with cognitive performance in early MS?
- (2020) Sinah Engel et al. Neurology-Neuroimmunology & Neuroinflammation
- The effect of physical activity on cognition relative to APOE genotype (PAAD-2): study protocol for a phase II randomized control trial
- (2020) Kyoung Shin Park et al. BMC Neurology
- Dementia prevention, intervention, and care: 2020 report of the Lancet Commission
- (2020) Gill Livingston et al. LANCET
- DNA methylation in Alzheimer’s disease: in brain and peripheral blood
- (2020) Xueli Wei et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Do menopausal status and APOE4 genotype alter the long-term effects of intensive lifestyle intervention on cognitive function in women with type 2 diabetes mellitus?
- (2020) Hussein N. Yassine et al. NEUROBIOLOGY OF AGING
- APOE Alleles and Diet in Brain Aging and Alzheimer’s Disease
- (2020) Hussein N. Yassine et al. Frontiers in Aging Neuroscience
- ApoE Lipidation as a Therapeutic Target in Alzheimer’s Disease
- (2020) Maria Fe Lanfranco et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of HDAC increases BDNF expression and promotes neuronal rewiring and functional recovery after brain injury
- (2020) Naoki Sada et al. Cell Death & Disease
- Associations Between Caffeine Consumption, Cognitive Decline, and Dementia: A Systematic Review
- (2020) J.Q. Alida Chen et al. JOURNAL OF ALZHEIMERS DISEASE
- Abnormal Sleep Behaviours Across the Spectrum of Alzheimer’s Disease Severity: Influence of APOE Genotypes and Lewy Bodies
- (2019) HBSc Ka Yi G. Koo et al. Current Alzheimer Research
- Gene-environment interactions in Alzheimer's disease: A potential path to precision medicine
- (2019) Aseel Eid et al. PHARMACOLOGY & THERAPEUTICS
- Effects of APOE on cognitive aging in community-dwelling older adults.
- (2019) Emilie T. Reas et al. NEUROPSYCHOLOGY
- Effect of aerobic exercise on cognition in younger adults
- (2019) Yaakov Stern et al. NEUROLOGY
- APOE Genotype Specific Effects on the Early Neurodegenerative Sequelae Following Chronic Repeated Mild Traumatic Brain Injury
- (2019) Phillip Muza et al. NEUROSCIENCE
- Exercise as a potential modulator of inflammation in patients with Alzheimer's disease measured in cerebrospinal fluid and plasma
- (2019) Camilla Steen Jensen et al. EXPERIMENTAL GERONTOLOGY
- Vitamin D concentration and risk of Alzheimer disease
- (2019) Kui Yang et al. MEDICINE
- Environmental factors and risk of multiple sclerosis: Findings from meta-analyses and Mendelian randomization studies
- (2019) Lazaros Belbasis et al. Multiple Sclerosis Journal
- Gene-by-environment interactions in Alzheimer’s disease and Parkinson’s disease
- (2019) Amy R. Dunn et al. NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS
- The relationship between environmental factors and different Parkinson's disease subtypes in Greece: Data analysis of the Hellenic Biobank of Parkinson's disease
- (2019) Efthalia Angelopoulou et al. PARKINSONISM & RELATED DISORDERS
- Vitamin D deficiency as a risk factor for dementia and Alzheimer’s disease: an updated meta-analysis
- (2019) Bingyan Chai et al. BMC Neurology
- Coffee intake and decreased amyloid pathology in human brain
- (2019) Jee Wook Kim et al. Translational Psychiatry
- Higher Blood Vitamin C Levels are Associated with Reduction of Apolipoprotein E E4-related Risks of Cognitive Decline in Women: The Nakajima Study
- (2018) Moeko Noguchi-Shinohara et al. JOURNAL OF ALZHEIMERS DISEASE
- Sunlight Incidence, Vitamin D Deficiency, and Alzheimer's Disease
- (2018) Alice Barros Câmara et al. JOURNAL OF MEDICINAL FOOD
- Human ApoE Isoforms Differentially Modulate Brain Glucose and Ketone Body Metabolism: Implications for Alzheimer's Disease Risk Reduction and Early Intervention
- (2018) Long Wu et al. JOURNAL OF NEUROSCIENCE
- Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion
- (2018) Erica Dresselhaus et al. PLoS One
- Recent studies on cellular and molecular mechanisms in Alzheimer’s disease: focus on epigenetic factors and histone deacetylase
- (2018) Harikesh Dubey et al. REVIEWS IN THE NEUROSCIENCES
- APOE and Alzheimer’s Disease: Neuroimaging of Metabolic and Cerebrovascular Dysfunction
- (2018) Jason A. Brandon et al. Frontiers in Aging Neuroscience
- Effect of the Apolipoprotein E Genotype on Cognitive Change During a Multidomain Lifestyle Intervention
- (2018) Alina Solomon et al. JAMA Neurology
- A Novel Perspective for Alzheimer's Disease: Vitamin D Receptor Suppression by Amyloid-β and Preventing the Amyloid-β Induced Alterations by Vitamin D in Cortical Neurons
- (2018) Erdinç Dursun et al. JOURNAL OF ALZHEIMERS DISEASE
- Acute Aerobic Exercise Increases Brain-Derived Neurotrophic Factor Levels in Elderly with Alzheimer's Disease
- (2018) Flávia Gomes de Melo Coelho et al. JOURNAL OF ALZHEIMERS DISEASE
- Effects of apolipoprotein E on nutritional metabolism in dementia
- (2018) Brandon C. Farmer et al. CURRENT OPINION IN LIPIDOLOGY
- APOEε4 impacts up-regulation of brain-derived neurotrophic factor after a six-month stretch and aerobic exercise intervention in mild cognitively impaired elderly African Americans: A pilot study
- (2017) Joanne S. Allard et al. EXPERIMENTAL GERONTOLOGY
- Apolipoprotein E4 is associated with improved cognitive function in Amazonian forager-horticulturalists with a high parasite burden
- (2017) Benjamin C. Trumble et al. FASEB JOURNAL
- Physical Exercise Moderates the Relationship of Apolipoprotein E (APOE) Genotype and Dementia Risk: A Population-Based Study
- (2017) Barbara Fenesi et al. JOURNAL OF ALZHEIMERS DISEASE
- Dementia prevention, intervention, and care
- (2017) Gill Livingston et al. LANCET
- Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis
- (2017) Susanna C Larsson et al. BMJ-British Medical Journal
- Modifiable pathways in Alzheimer’s disease: Mendelian randomisation analysis
- (2017) Susanna C Larsson et al. BMJ-British Medical Journal
- Particulate air pollutants, APOE alleles and their contributions to cognitive impairment in older women and to amyloidogenesis in experimental models
- (2017) M Cacciottolo et al. Translational Psychiatry
- 1α,25-dihydroxyvitamin D3 Interacts with Curcuminoids to Stimulate Amyloid-β Clearance by Macrophages of Alzheimer's Disease Patients
- (2017) Ava Masoumi et al. JOURNAL OF ALZHEIMERS DISEASE
- Exercise Plays a Preventive Role Against Alzheimer's Disease
- (2017) Zsolt Radak et al. JOURNAL OF ALZHEIMERS DISEASE
- Molecular Basis of Familial and Sporadic Alzheimer's Disease
- (2016) Jolanta Dorszewska et al. Current Alzheimer Research
- Alzheimer's disease and diet: a systematic review
- (2016) Miryam Yusufov et al. INTERNATIONAL JOURNAL OF NEUROSCIENCE
- Associations of APOE ε4 With Health and Financial Literacy Among Community-Based Older Adults Without Dementia
- (2016) Christopher C Stewart et al. JOURNALS OF GERONTOLOGY SERIES B-PSYCHOLOGICAL SCIENCES AND SOCIAL SCIENCES
- Interactive effects of physical activity and APOE-ε4 on white matter tract diffusivity in healthy elders
- (2016) J. Carson Smith et al. NEUROIMAGE
- Vitamin D deficiency might pose a greater risk for ApoEɛ4 non-carrier Alzheimer’s disease patients
- (2016) Erdinç Dursun et al. NEUROLOGICAL SCIENCES
- APOEε4 and the associations of seafood and long-chain omega-3 fatty acids with cognitive decline
- (2016) Ondine van de Rest et al. NEUROLOGY
- Vitamin D and its effects on cardiovascular diseases: a comprehensive review
- (2016) Nonanzit Pérez-Hernández et al. KOREAN JOURNAL OF INTERNAL MEDICINE
- Pesticide exposure and risk of Alzheimer’s disease: a systematic review and meta-analysis
- (2016) Dandan Yan et al. Scientific Reports
- Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia
- (2015) Anna-Maija Tolppanen et al. Alzheimers & Dementia
- Role of Environmental Contaminants in the Etiology of Alzheimer’s Disease: A Review
- (2015) Manivannan Yegambaram et al. Current Alzheimer Research
- APOE*E2 allele delays age of onset in PSEN1 E280A Alzheimer’s disease
- (2015) J I Vélez et al. MOLECULAR PSYCHIATRY
- Interaction between years of education andAPOEε4 status on frontal and temporal metabolism
- (2015) Eider M. Arenaza-Urquijo et al. NEUROLOGY
- Interaction of Cigarette Smoking History WithAPOEGenotype and Age on Amyloid Level, Glucose Metabolism, and Neurocognition in Cognitively Normal Elders
- (2015) Timothy C. Durazzo et al. NICOTINE & TOBACCO RESEARCH
- Can education rescue genetic liability for cognitive decline?
- (2015) C. Justin Cook et al. SOCIAL SCIENCE & MEDICINE
- Is the risk of Alzheimer’s disease and dementia declining?
- (2015) Kenneth M Langa Alzheimers Research & Therapy
- Smoking Is Associated with an Increased Risk of Dementia: A Meta-Analysis of Prospective Cohort Studies with Investigation of Potential Effect Modifiers
- (2015) Guochao Zhong et al. PLoS One
- 25-Hydroxyvitamin D, APOE ɛ4 genotype and cognitive function: findings from the 1958 British birth cohort
- (2014) J Maddock et al. EUROPEAN JOURNAL OF CLINICAL NUTRITION
- Gene-Environment Interactions: Lifetime Cognitive Activity, APOE Genotype, and Beta-Amyloid Burden
- (2014) M. Wirth et al. JOURNAL OF NEUROSCIENCE
- Associations Between ApoEε4 Carrier Status and Serum BDNF Levels—New Insights into the Molecular Mechanism of ApoEε4 Actions in Alzheimer’s Disease
- (2014) Yu-Hui Liu et al. MOLECULAR NEUROBIOLOGY
- Vitamin D and the risk of dementia and Alzheimer disease
- (2014) T. J. Littlejohns et al. NEUROLOGY
- Interactions of metals and Apolipoprotein E in Alzheimer’s disease
- (2014) He Xu et al. Frontiers in Aging Neuroscience
- Elevated Serum Pesticide Levels and Risk for Alzheimer Disease
- (2014) Jason R. Richardson et al. JAMA Neurology
- The Relationship Between Midlife and Late Life Alcohol Consumption, APOE e4 and the Decline in Learning and Memory Among Older Adults
- (2013) Brian Downer et al. ALCOHOL AND ALCOHOLISM
- DHA supplementation improved both memory and reaction time in healthy young adults: a randomized controlled trial
- (2013) Welma Stonehouse et al. AMERICAN JOURNAL OF CLINICAL NUTRITION
- Alzheimer disease in the United States (2010-2050) estimated using the 2010 census
- (2013) L. E. Hebert et al. NEUROLOGY
- APOE e4 genotype and cigarette smoking in adults with normal cognition and mild cognitive impairment: a retrospective baseline analysis of a national dataset
- (2013) Raj K. Kalapatapu et al. AMERICAN JOURNAL OF DRUG AND ALCOHOL ABUSE
- Modification of the Relationship of the Apolipoprotein E ε4 Allele to the Risk of Alzheimer Disease and Neurofibrillary Tangle Density by Sleep
- (2013) Andrew S. P. Lim et al. JAMA Neurology
- Effect of Apolipoprotein E Genotype and Diet on Apolipoprotein E Lipidation and Amyloid Peptides
- (2013) Angela J. Hanson et al. JAMA Neurology
- Exercise Engagement as a Moderator of the Effects of APOE Genotype on Amyloid Deposition
- (2012) Julie M. Bugg ARCHIVES OF NEUROLOGY
- Running-induced epigenetic and gene expression changes in the adolescent brain
- (2012) Jean LeBeau Abel et al. INTERNATIONAL JOURNAL OF DEVELOPMENTAL NEUROSCIENCE
- How can elderly apolipoprotein E ε4 carriers remain free from dementia?
- (2012) Camilla Ferrari et al. NEUROBIOLOGY OF AGING
- Nicotine treatment of mild cognitive impairment: A 6-month double-blind pilot clinical trial
- (2012) P. Newhouse et al. NEUROLOGY
- Vitamin D, cognition, and dementia: A systematic review and meta-analysis
- (2012) C. Balion et al. NEUROLOGY
- Apolipoprotein E Sets the Stage: Response to Injury Triggers Neuropathology
- (2012) Robert W. Mahley et al. NEURON
- Do apolipoprotein E genotype and educational attainment predict the rate of cognitive decline in normal aging? A 12-year follow-up of the Maastricht Aging Study.
- (2012) Pascal W. M. Van Gerven et al. NEUROPSYCHOLOGY
- APOE ɛ4, an Alzheimer’s disease susceptibility allele and smoking cessation
- (2012) R L Ashare et al. PHARMACOGENOMICS JOURNAL
- ApoE genotype: from geographic distribution to function and responsiveness to dietary factors
- (2012) Sarah Egert et al. PROCEEDINGS OF THE NUTRITION SOCIETY
- Current alcohol consumption and its relationship to incident dementia: results from a 3-year follow-up study among primary care attenders aged 75 years and older
- (2011) S. Weyerer et al. AGE AND AGEING
- Interaction of apolipoprotein E genotype with smoking and physical inactivity on coronary heart disease risk in men and women
- (2011) Jaana Gustavsson et al. ATHEROSCLEROSIS
- Dietary Omega 3 Polyunsaturated Fatty Acids and Alzheimers Disease: Interaction with Apolipoprotein E Genotype
- (2011) P. Barberger-Gateau et al. Current Alzheimer Research
- APOE ε4 is associated with higher vitamin D levels in targeted replacement mice and humans
- (2011) Patricia Huebbe et al. FASEB JOURNAL
- Apolipoprotein E in Alzheimer's disease and other neurological disorders
- (2011) Philip B Verghese et al. LANCET NEUROLOGY
- Education halves the risk of dementia due to apolipoprotein ε4 allele: a collaborative study from the Swedish Brain Power initiative
- (2011) Hui-Xin Wang et al. NEUROBIOLOGY OF AGING
- Effect of different exercise protocols on histone acetyltransferases and histone deacetylases activities in rat hippocampus
- (2011) V.R. Elsner et al. NEUROSCIENCE
- Increased effect of the ApoE gene on survival at advanced age in healthy and long-lived Danes: two nationwide cohort studies
- (2010) Rune Jacobsen et al. AGING CELL
- Alcohol consumption and risk of recurrent cardiovascular events and mortality in patients with clinically manifest vascular disease and diabetes mellitus: The Second Manifestations of ARTerial (SMART) disease study
- (2010) J.W.J. Beulens et al. ATHEROSCLEROSIS
- Vitamin D and multiple health outcomes in the Harvard cohorts
- (2010) Melissa Y. Wei et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Occupational exposure to pesticides increases the risk of incident AD: The Cache County Study
- (2010) K. M. Hayden et al. NEUROLOGY
- Positive Effects of Cholinergic Stimulation Favor Young APOE ɛ4 Carriers
- (2010) Natalie L Marchant et al. NEUROPSYCHOPHARMACOLOGY
- The effect of alcohol and tobacco consumption, and apolipoprotein E genotype, on the age of onset in Alzheimer's disease
- (2009) Dylan G. Harwood et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Study of the ketogenic agent AC-1202 in mild to moderate Alzheimer's disease: a randomized, double-blind, placebo-controlled, multicenter trial
- (2009) Samuel T Henderson et al. Nutrition & Metabolism
- Apolipoprotein E ɛ4 magnifies lifestyle risks for dementia: a population-based study
- (2008) Miia Kivipelto et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Physical activity and risk of neurodegenerative disease: a systematic review of prospective evidence
- (2008) M. Hamer et al. PSYCHOLOGICAL MEDICINE
- The APOE ε4 allele increases the risk of impaired spatial working memory in obstructive sleep apnea
- (2008) Filomena I.I. Cosentino et al. SLEEP MEDICINE
- The association of APOE genotype and cognitive decline in interaction with risk factors in a 65–69 year old community sample
- (2008) Helen Christensen et al. BMC Geriatrics
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started