Transgenerational latent early-life associated regulation unites environment and genetics across generations

Effects of the Social Environment and Stress on Glucocorticoid Receptor Gene Methylation: A Systematic Review

(2016) Gustavo Turecki et al.   BIOLOGICAL PSYCHIATRY

Understanding type 2 diabetes: from genetics to epigenetics

(2015) Gregory Alexander Raciti et al.   ACTA DIABETOLOGICA

Regulation of chromatin states by drugs of abuse

(2015) Deena M Walker et al.   CURRENT OPINION IN NEUROBIOLOGY

The epigenetic clock is correlated with physical and cognitive fitness in the Lothian Birth Cohort 1936

(2015) Riccardo E Marioni et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Epigenomics, gestational programming and risk of metabolic syndrome

(2015) M Desai et al.   INTERNATIONAL JOURNAL OF OBESITY

The metabolic syndrome in a memory clinic population: Relation with clinical profile and prognosis

(2015) Lieza G. Exalto et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Epigenetic mechanisms in Parkinson's disease

(2015) Ya Feng et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Biological and clinical characteristics of the European Friedreich's Ataxia Consortium for Translational Studies (EFACTS) cohort: a cross-sectional analysis of baseline data

(2015) Kathrin Reetz et al.   LANCET NEUROLOGY

SOX4 interacts with EZH2 and HDAC3 to suppress microRNA-31 in invasive esophageal cancer cells

(2015) Rainelli B Koumangoye et al.   Molecular Cancer

Increased acetyl and total histone levels in post-mortem Alzheimer's disease brain

(2015) Pritika J. Narayan et al.   NEUROBIOLOGY OF DISEASE

Clinical variables associated with treatment changes in Parkinson’s disease: results from the longitudinal phase of the REASON study

(2015) Giovanni Abbruzzese et al.   NEUROLOGICAL SCIENCES

Antidepressant action of HDAC inhibition in the prefrontal cortex

(2015) H.E. Covington et al.   NEUROSCIENCE

Transgenerational inheritance of metabolic disease

(2015) Rachel Stegemann et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Microbiota and host determinants of behavioural phenotype in maternally separated mice

(2015) G. De Palma et al.   Nature Communications

DNA methylation age of blood predicts all-cause mortality in later life

(2015) Riccardo E Marioni et al.   GENOME BIOLOGY

Association of Brain DNA Methylation inSORL1,ABCA7,HLA-DRB5,SLC24A4, andBIN1With Pathological Diagnosis of Alzheimer Disease

(2015) Lei Yu et al.   JAMA Neurology

2014 Alzheimer's disease facts and figures

(2014)   Alzheimers & Dementia

Genome-wide Methylomic Analysis of Monozygotic Twins Discordant for Adolescent Depression

(2014) Emma L. Dempster et al.   BIOLOGICAL PSYCHIATRY

DNA methylation and expression ofKCNQ3in bipolar disorder

(2014) Zachary Kaminsky et al.   BIPOLAR DISORDERS

The longitudinal course of sleep timing and circadian preferences in adults with bipolar disorder

(2014) Mohammad A Seleem et al.   BIPOLAR DISORDERS

Applying Epigenetics to Alzheimer’s Disease via the Latent Early–life Associated Regulation (LEARn) Model

(2014) Bryan Maloney et al.   Current Alzheimer Research

Paternal high-fat diet consumption induces common changes in the transcriptomes of retroperitoneal adipose and pancreatic islet tissues in female rat offspring

(2014) Sheau-Fang Ng et al.   FASEB JOURNAL

Demonstration of the usefulness of epigenetic cancer risk prediction by a multicentre prospective cohort study

(2014) Kiyoshi Asada et al.   GUT

Epigenetic modulation of BDNF gene: Differences in DNA methylation between unipolar and bipolar patients

(2014) Bernardo Dell׳Osso et al.   JOURNAL OF AFFECTIVE DISORDERS

Histone Hyperacetylation Up-regulates Protein Kinase Cδ in Dopaminergic Neurons to Induce Cell Death

(2014) Huajun Jin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Asperger syndrome in males over two decades: stability and predictors of diagnosis

(2014) Adam Helles et al.   JOURNAL OF CHILD PSYCHOLOGY AND PSYCHIATRY

The Gene Silencing Transcription Factor REST Represses miR-132 Expression in Hippocampal Neurons Destined to Die

(2014) Jee-Yeon Hwang et al.   JOURNAL OF MOLECULAR BIOLOGY

Is the Aluminum Hypothesis Dead?

(2014) Theodore I. Lidsky   JOURNAL OF OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Parkinson's disease correlates with promoter methylation in the α-synuclein gene

(2014) Lasse Pihlstrøm et al.   MOVEMENT DISORDERS

Biological insights from 108 schizophrenia-associated genetic loci

(2014)   NATURE

A framework for the interpretation of de novo mutation in human disease

(2014) Kaitlin E Samocha et al.   NATURE GENETICS

Parental Obesity and Risk of Autism Spectrum Disorder

(2014) P. Suren et al.   PEDIATRICS

Epigenetic suppression of hippocampal BDNF mediates the memory deficiency induced by amyloid fibrils

(2014) Bei-Yun Wang et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

DNA methylation of BDNF as a biomarker of early-life adversity

(2014) Marija Kundakovic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Do negative symptoms of schizophrenia change over time? A meta-analysis of longitudinal data

(2014) M. Savill et al.   PSYCHOLOGICAL MEDICINE

Pesticides exposure as etiological factors of Parkinson's disease and other neurodegenerative diseases—A mechanistic approach

(2014) Maria Teresa Baltazar et al.   TOXICOLOGY LETTERS

Holo-APP and G-protein-mediated signaling are required for sAPPα-induced activation of the Akt survival pathway

(2014) N Milosch et al.   Cell Death & Disease

Age-Associated Sperm DNA Methylation Alterations: Possible Implications in Offspring Disease Susceptibility

(2014) Timothy G. Jenkins et al.   PLoS Genetics

Identification of Pathways for Bipolar Disorder

(2014) John I. Nurnberger et al.   JAMA Psychiatry

Paternal Age at Childbearing and Offspring Psychiatric and Academic Morbidity

(2014) Brian M. D’Onofrio et al.   JAMA Psychiatry

A Comprehensive Assessment of Parental Age and Psychiatric Disorders

(2014) John J. McGrath et al.   JAMA Psychiatry

Grand-paternal age and the development of autism-like symptoms in mice progeny

(2014) S Sampino et al.   Translational Psychiatry

The impact of environmental factors in severe psychiatric disorders

(2014) Andrea Schmitt et al.   Frontiers in Neuroscience

Histone-acetylation: a link between Alzheimer's disease and post-traumatic stress disorder?

(2014) Sanaz Bahari-Javan et al.   Frontiers in Neuroscience

New Ethical Issues for Genetic Counseling in Common Mental Disorders

(2013) Elliot S. Gershon et al.   AMERICAN JOURNAL OF PSYCHIATRY

Intergenerational Health Responses to Adverse and Enriched Environments

(2013) Lars Olov Bygren   Annual Review of Public Health

Early environments, glucocorticoid receptors, and behavioral epigenetics.

(2013) Frances A. Champagne   BEHAVIORAL NEUROSCIENCE

Transgenerational effects of prenatal exposure to the 1944-45 Dutch famine

(2013) MVE Veenendaal et al.   BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY

Military Risk Factors for Cognitive Decline, Dementia and Alzheimer’s Disease

(2013) Dallas Veitch et al.   Current Alzheimer Research

Epigenetic dysregulation of SHANK3 in brain tissues from individuals with autism spectrum disorders

(2013) Li Zhu et al.   HUMAN MOLECULAR GENETICS

Disrupting Intergenerational Continuity in Harsh and Abusive Parenting: The Importance of a Nurturing Relationship With a Romantic Partner

(2013) Rand D. Conger et al.   JOURNAL OF ADOLESCENT HEALTH

Safe, Stable, Nurturing Relationships Break the Intergenerational Cycle of Abuse: A Prospective Nationally Representative Cohort of Children in the United Kingdom

(2013) Sara R. Jaffee et al.   JOURNAL OF ADOLESCENT HEALTH

Neurobiological disease etiology and inheritance: an epigenetic perspective

(2013) B. J. Saab et al.   JOURNAL OF EXPERIMENTAL BIOLOGY

Methylomic analysis of monozygotic twins discordant for autism spectrum disorder and related behavioural traits

(2013) C C Y Wong et al.   MOLECULAR PSYCHIATRY

Common DNA methylation alterations in multiple brain regions in autism

(2013) C Ladd-Acosta et al.   MOLECULAR PSYCHIATRY

Parental olfactory experience influences behavior and neural structure in subsequent generations

(2013) Brian G Dias et al.   NATURE NEUROSCIENCE

Consistent decrease in global DNA methylation and hydroxymethylation in the hippocampus of Alzheimer's disease patients

(2013) Leonidas Chouliaras et al.   NEUROBIOLOGY OF AGING

Mechanisms of transgenerational inheritance of addictive-like behaviors

(2013) F.M. Vassoler et al.   NEUROSCIENCE

Acetylation of Drosha on the N-Terminus Inhibits Its Degradation by Ubiquitination

(2013) Xiaoli Tang et al.   PLoS One

Maternal PTSD associates with greater glucocorticoid sensitivity in offspring of Holocaust survivors

(2013) Amy Lehrner et al.   PSYCHONEUROENDOCRINOLOGY

Autism as early neurodevelopmental disorder: evidence for an sAPPα-mediated anabolic pathway

(2013) Debomoy K. Lahiri et al.   Frontiers in Cellular Neuroscience

Low paternal dietary folate alters the mouse sperm epigenome and is associated with negative pregnancy outcomes

(2013) R. Lambrot et al.   Nature Communications

Assessment of Infantile Mineral Imbalances in Autism Spectrum Disorders (ASDs)

(2013) Hiroshi Yasuda et al.   International Journal of Environmental Research and Public Health

Epigenetic Findings in Autism: New Perspectives for Therapy

(2013) Dario Siniscalco et al.   International Journal of Environmental Research and Public Health

Transgenerational Epigenetic Effects on Brain Functions

(2012) Johannes Bohacek et al.   BIOLOGICAL PSYCHIATRY

Formulation of the Multi-Hit Model With a Non-Poisson Distribution of Hits

(2012) Oleg N. Vassiliev   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

Range of genetic mutations associated with severe non-syndromic sporadic intellectual disability: an exome sequencing study

(2012) Anita Rauch et al.   LANCET

Epigenetic inheritance of a cocaine-resistance phenotype

(2012) Fair M Vassoler et al.   NATURE NEUROSCIENCE

Epigenetic Inheritance of Disease and Disease Risk

(2012) Johannes Bohacek et al.   NEUROPSYCHOPHARMACOLOGY

Evaluation of the effects of treatment with sAPPα on functional and histological outcome following controlled cortical impact injury in mice

(2012) Frances Corrigan et al.   NEUROSCIENCE LETTERS

Emerging neurotoxic mechanisms in environmental factors-induced neurodegeneration

(2012) Anumantha Kanthasamy et al.   NEUROTOXICOLOGY

Epigenetic transgenerational inheritance of altered stress responses

(2012) D. Crews et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The role of nutraceuticals in the management of autism

(2012) Abdulrahman S. Alanazi   SAUDI PHARMACEUTICAL JOURNAL

Gene × environment interaction by a longitudinal epigenome-wide association study (LEWAS) overcomes limitations of genome-wide association study (GWAS)

(2012) Debomoy K Lahiri et al.   Epigenomics

A High-Risk Study of Bipolar Disorder

(2011) John I. Nurnberger   ARCHIVES OF GENERAL PSYCHIATRY

Paternal Transmission of Stress-Induced Pathologies

(2011) David M. Dietz et al.   BIOLOGICAL PSYCHIATRY

Cell functional enviromics: Unravelling the function of environmental factors

(2011) Ana P Teixeira et al.   BMC Systems Biology

The epigenomic interface between genome and environment in common complex diseases

(2011) C. G. Bell et al.   Briefings in Functional Genomics

TET Family Proteins and Their Role in Stem Cell Differentiation and Transformation

(2011) Luisa Cimmino et al.   Cell Stem Cell

Current Drug Targets for Modulating Alzheimer's Amyloid Precursor Protein: Role of Specific Micro-RNA Species

(2011) J.M. Long et al.   CURRENT MEDICINAL CHEMISTRY

Transgenerational inheritance of stress pathology

(2011) Stephen G. Matthews et al.   EXPERIMENTAL NEUROLOGY

Stress, epigenetic control of gene expression and memory formation

(2011) Alexandra F. Trollope et al.   EXPERIMENTAL NEUROLOGY

Epigenetics DNA methylation in the core ataxin-2 gene promoter: novel physiological and pathological implications

(2011) José Miguel Laffita-Mesa et al.   HUMAN GENETICS

Early Prenatal Stress Epigenetically Programs Dysmasculinization in Second-Generation Offspring via the Paternal Lineage

(2011) C. P. Morgan et al.   JOURNAL OF NEUROSCIENCE

Chronic High-Fat Diet Drives Postnatal Epigenetic Regulation of μ-Opioid Receptor in the Brain

(2011) Zivjena Vucetic et al.   NEUROPSYCHOPHARMACOLOGY

Epigenetic modifications induced by early enrichment are associated with changes in timing of induction of BDNF expression

(2011) Igor Branchi et al.   NEUROSCIENCE LETTERS

Paraquat induces epigenetic changes by promoting histone acetylation in cell culture models of dopaminergic degeneration

(2011) C. Song et al.   NEUROTOXICOLOGY

Increased Secreted Amyloid Precursor Protein-α (sAPPα) in Severe Autism: Proposal of a Specific, Anabolic Pathway and Putative Biomarker

(2011) Balmiki Ray et al.   PLoS One

Influence of Early Stress on Social Abilities and Serotonergic Functions across Generations in Mice

(2011) Tamara B. Franklin et al.   PLoS One

Paternally Induced Transgenerational Environmental Reprogramming of Metabolic Gene Expression in Mammals

(2010) Benjamin R. Carone et al.   CELL

Transgenerational Inheritance of Glucose Intolerance in a Mouse Model of Neonatal Overnutrition

(2010) Thais Pentinat et al.   ENDOCRINOLOGY

Exposure to Metal-Rich Particulate Matter Modifies the Expression of Candidate MicroRNAs in Peripheral Blood Leukocytes

(2010) Valentina Bollati et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Evidence for microRNA involvement in exercise-associated neutrophil gene expression changes

(2010) Shlomit Radom-Aizik et al.   JOURNAL OF APPLIED PHYSIOLOGY

Cross talk between microRNA and epigenetic regulation in adult neurogenesis

(2010) Keith E. Szulwach et al.   JOURNAL OF CELL BIOLOGY

Epigenetic modifications as key regulators of Waldenstrom's Macroglobulinemia biology

(2010) Antonio Sacco et al.   Journal of Hematology & Oncology

Cocaine-Induced Chromatin Remodeling Increases Brain-Derived Neurotrophic Factor Transcription in the Rat Medial Prefrontal Cortex, Which Alters the Reinforcing Efficacy of Cocaine

(2010) G. Sadri-Vakili et al.   JOURNAL OF NEUROSCIENCE

Circulating neprilysin clears brain amyloid

(2010) Yinxing Liu et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Environmental Neurotoxic Pesticide Increases Histone Acetylation to Promote Apoptosis in Dopaminergic Neuronal Cells: Relevance to Epigenetic Mechanisms of Neurodegeneration

(2010) C. Song et al.   MOLECULAR PHARMACOLOGY

The Changing Role of Mother of the Mentally Ill: From Schizophrenogenic Mother to Multigenerational Caregiver

(2010) Mary V. Seeman   PSYCHIATRY-INTERPERSONAL AND BIOLOGICAL PROCESSES

Alterations in the developing testis transcriptome following embryonic vinclozolin exposure

(2010) Tracy M. Clement et al.   REPRODUCTIVE TOXICOLOGY

Autism spectrum disorder in fragile X syndrome: A longitudinal evaluation

(2009) R. Nick Hernandez et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

DNA methylation differences after exposure to prenatal famine are common and timing- and sex-specific

(2009) Elmar W. Tobi et al.   HUMAN MOLECULAR GENETICS

Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome

(2009) Andreas Plagemann et al.   JOURNAL OF PHYSIOLOGY-LONDON

The LEARn model: an epigenetic explanation for idiopathic neurobiological diseases

(2009) D K Lahiri et al.   MOLECULAR PSYCHIATRY

Epigenetic Differences in Cortical Neurons from a Pair of Monozygotic Twins Discordant for Alzheimer's Disease

(2009) Diego Mastroeni et al.   PLoS One

Intergenerational transmission of programmed effects: public health consequences

(2009) Amanda J. Drake et al.   TRENDS IN ENDOCRINOLOGY AND METABOLISM

Downregulation of microRNA expression in the lungs of rats exposed to cigarette smoke

(2008) Alberto Izzotti et al.   FASEB JOURNAL

Genetics, environmental factors and the emerging role of epigenetics in neurodegenerative diseases

(2008) Lucia Migliore et al.   MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS

Moving AHEAD with an international human epigenome project

(2008) et al.   NATURE

Promoter-Wide Hypermethylation of the Ribosomal RNA Gene Promoter in the Suicide Brain

(2008) Patrick O. McGowan et al.   PLoS One

Persistent epigenetic differences associated with prenatal exposure to famine in humans

(2008) B. T. Heijmans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vinclozolin—The lack of a transgenerational effect after oral maternal exposure during organogenesis

(2008) S SCHNEIDER et al.   REPRODUCTIVE TOXICOLOGY