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Title
Early-Onset Alzheimer’s Disease: What Is Missing in Research?
Authors
Keywords
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Journal
Current Neurology and Neuroscience Reports
Volume 21, Issue 2, Pages -
Publisher
Springer Science and Business Media LLC
Online
2021-01-19
DOI
10.1007/s11910-020-01090-y
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Note: Only part of the references are listed.- DNA methylation age acceleration is associated with ALS age of onset and survival
- (2020) Ming Zhang et al. ACTA NEUROPATHOLOGICA
- Amyloid and Tau PET Imaging of Alzheimer Disease and Other Neurodegenerative Conditions
- (2020) Paul A. Rowley et al. SEMINARS IN ULTRASOUND CT AND MRI
- Blood–brain barrier breakdown is an early biomarker of human cognitive dysfunction
- (2019) Daniel A. Nation et al. NATURE MEDICINE
- Serum neurofilament dynamics predicts neurodegeneration and clinical progression in presymptomatic Alzheimer’s disease
- (2019) Oliver Preische et al. NATURE MEDICINE
- Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
- (2019) Brian W. Kunkle et al. NATURE GENETICS
- Tau PET in autosomal dominant Alzheimer’s disease: relationship with cognition, dementia and other biomarkers
- (2019) Brian A Gordon et al. BRAIN
- SORL1 genetic variants and Alzheimer disease risk: a literature review and meta-analysis of sequencing data
- (2019) Dominique Campion et al. ACTA NEUROPATHOLOGICA
- Performance of Fully Automated Plasma Assays as Screening Tests for Alzheimer Disease–Related β-Amyloid Status
- (2019) Sebastian Palmqvist et al. JAMA Neurology
- Genetic and epigenetic study of an Alzheimer’s disease family with monozygotic triplets
- (2019) Ming Zhang et al. BRAIN
- NIA-AA Research Framework: Toward a biological definition of Alzheimer's disease
- (2018) Clifford R. Jack et al. Alzheimers & Dementia
- Amyloid blood biomarker detects Alzheimer's disease
- (2018) Andreas Nabers et al. EMBO Molecular Medicine
- A Decade of Blood Biomarkers for Alzheimer’s Disease Research: An Evolving Field, Improving Study Designs, and the Challenge of Replication
- (2018) Liu Shi et al. JOURNAL OF ALZHEIMERS DISEASE
- Assessing Synaptic Density in Alzheimer Disease With Synaptic Vesicle Glycoprotein 2A Positron Emission Tomographic Imaging
- (2018) Ming-Kai Chen et al. JAMA Neurology
- Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
- (2018) Fuyuki Kametani et al. Frontiers in Neuroscience
- A C6orf10/LOC101929163 locus is associated with age of onset in C9orf72 carriers
- (2018) Ming Zhang et al. BRAIN
- Biomarkers for Alzheimer's disease: current status and prospects for the future
- (2018) K. Blennow et al. JOURNAL OF INTERNAL MEDICINE
- Longitudinal cognitive and biomarker changes in dominantly inherited Alzheimer disease
- (2018) Eric McDade et al. NEUROLOGY
- New insights into the role of TREM2 in Alzheimer’s disease
- (2018) Maud Gratuze et al. Molecular Neurodegeneration
- Characterization of pathogenic SORL1 genetic variants for association with Alzheimer’s disease: a clinical interpretation strategy
- (2017) Henne Holstege et al. EUROPEAN JOURNAL OF HUMAN GENETICS
- Alzheimer's disease
- (2017) C. A. Lane et al. EUROPEAN JOURNAL OF NEUROLOGY
- Neurotoxic reactive astrocytes are induced by activated microglia
- (2017) Shane A. Liddelow et al. NATURE
- Cerebral blood flow regulation and neurovascular dysfunction in Alzheimer disease
- (2017) Kassandra Kisler et al. NATURE REVIEWS NEUROSCIENCE
- Maintained memory in aging is associated with young epigenetic age
- (2017) Sofie Degerman et al. NEUROBIOLOGY OF AGING
- Excessive tau accumulation in the parieto-occipital cortex characterizes early-onset Alzheimer's disease
- (2017) Hanna Cho et al. NEUROBIOLOGY OF AGING
- Association of Plasma Neurofilament Light With Neurodegeneration in Patients With Alzheimer Disease
- (2017) Niklas Mattsson et al. JAMA Neurology
- A comprehensive study of the genetic impact of rare variants in SORL1 in European early-onset Alzheimer’s disease
- (2016) Jan Verheijen et al. ACTA NEUROPATHOLOGICA
- Risk factor SORL1: from genetic association to functional validation in Alzheimer’s disease
- (2016) Olav M. Andersen et al. ACTA NEUROPATHOLOGICA
- Brain atrophy in Alzheimer’s Disease and aging
- (2016) Lorenzo Pini et al. AGEING RESEARCH REVIEWS
- Huntington's disease accelerates epigenetic aging of human brain and disrupts DNA methylation levels
- (2016) Steve Horvath et al. Aging-US
- The relationship between cerebrospinal fluid markers of Alzheimer pathology and positron emission tomography tau imaging
- (2016) Brian A. Gordon et al. BRAIN
- CSF and blood biomarkers for the diagnosis of Alzheimer's disease: a systematic review and meta-analysis
- (2016) Bob Olsson et al. LANCET NEUROLOGY
- Analysis of protein-coding genetic variation in 60,706 humans
- (2016) Monkol Lek et al. NATURE
- A/T/N: An unbiased descriptive classification scheme for Alzheimer disease biomarkers
- (2016) Clifford R. Jack et al. NEUROLOGY
- Temporal T807 binding correlates with CSF tau and phospho-tau in normal elderly
- (2016) Jasmeer P. Chhatwal et al. NEUROLOGY
- Tau and Aβ imaging, CSF measures, and cognition in Alzheimer’s disease
- (2016) Matthew R. Brier et al. Science Translational Medicine
- Plasma Concentration of the Neurofilament Light Protein (NFL) is a Biomarker of CNS Injury in HIV Infection: A Cross-Sectional Study
- (2016) Magnus Gisslén et al. EBioMedicine
- Epigenetic age of the pre-frontal cortex is associated with neuritic plaques, amyloid load, and Alzheimer’s disease related cognitive functioning
- (2015) Morgan E Levine et al. Aging-US
- Increased epigenetic age and granulocyte counts in the blood of Parkinson's disease patients
- (2015) Steve Horvath et al. Aging-US
- The role of TREM2 R47H as a risk factor for Alzheimer's disease, frontotemporal lobar degeneration, amyotrophic lateral sclerosis, and Parkinson's disease
- (2015) Christina M. Lill et al. Alzheimers & Dementia
- Coding mutations inSORL1and Alzheimer disease
- (2015) Badri N. Vardarajan et al. ANNALS OF NEUROLOGY
- Differentiated clinical presentation of early and late-onset Alzheimer’s disease: is 65 years of age providing a reliable threshold?
- (2015) Antonio Palasí et al. JOURNAL OF NEUROLOGY
- SORL1 rare variants: a major risk factor for familial early-onset Alzheimer’s disease
- (2015) G Nicolas et al. MOLECULAR PSYCHIATRY
- Neuropathologic assessment of participants in two multi-center longitudinal observational studies: The Alzheimer Disease Neuroimaging Initiative (ADNI) and the Dominantly Inherited Alzheimer Network (DIAN)
- (2015) Nigel J. Cairns et al. NEUROPATHOLOGY
- Memory Consolidation
- (2015) Larry R. Squire et al. Cold Spring Harbor Perspectives in Biology
- The Patterns of Inheritance in Early-Onset Dementia
- (2014) Anna I. Jarmolowicz et al. American Journal of Alzheimers Disease and Other Dementias
- Estimating the burden of early onset dementia; systematic review of disease prevalence
- (2014) M. A. Lambert et al. EUROPEAN JOURNAL OF NEUROLOGY
- Altered microglial response to Aβ plaques in APPPS1-21 mice heterozygous for TREM2
- (2014) Jason D Ulrich et al. Molecular Neurodegeneration
- Symptom onset in autosomal dominant Alzheimer disease: A systematic review and meta-analysis
- (2014) D. C. Ryman et al. NEUROLOGY
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- (2014) Teng Jiang et al. NEUROPSYCHOPHARMACOLOGY
- Novel plasma biomarker surrogating cerebral amyloid deposition
- (2014) Naoki KANEKO et al. PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- TREM2 mutations implicated in neurodegeneration impair cell surface transport and phagocytosis
- (2014) G. Kleinberger et al. Science Translational Medicine
- Association of MAPT haplotypes with Alzheimer’s disease risk and MAPT brain gene expression levels
- (2014) Mariet Allen et al. Alzheimers Research & Therapy
- Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
- (2013) Jean-Charles Lambert et al. NATURE GENETICS
- Different patterns of gray matter atrophy in early- and late-onset Alzheimer’s disease
- (2013) Christiane Möller et al. NEUROBIOLOGY OF AGING
- Regional variability of imaging biomarkers in autosomal dominant Alzheimer's disease
- (2013) T. L. S. Benzinger et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) Kinga Szigeti et al. Alzheimers Research & Therapy
- Plasma amyloid beta measurements - a desired but elusive Alzheimer's disease biomarker
- (2013) Jon B Toledo et al. Alzheimers Research & Therapy
- Neuropathological Alterations in Alzheimer Disease
- (2013) A. Serrano-Pozo et al. Cold Spring Harbor Perspectives in Medicine
- DNA methylation age of human tissues and cell types
- (2013) Steve Horvath GENOME BIOLOGY
- High frequency of potentially pathogenic SORL1 mutations in autosomal dominant early-onset Alzheimer disease
- (2012) C Pottier et al. MOLECULAR PSYCHIATRY
- A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline
- (2012) Thorlakur Jonsson et al. NATURE
- Rates of Decline in Alzheimer Disease Decrease with Age
- (2012) Dominic Holland et al. PLoS One
- Meta-analysis of the Association Between Variants in SORL1 and Alzheimer Disease
- (2011) Christiane Reitz ARCHIVES OF NEUROLOGY
- Autosomal Recessive Causes Likely in Early-Onset Alzheimer Disease
- (2011) Thomas S. Wingo ARCHIVES OF NEUROLOGY
- Neuropathologically defined subtypes of Alzheimer's disease with distinct clinical characteristics: a retrospective study
- (2011) Melissa E Murray et al. LANCET NEUROLOGY
- Epidemiology of Alzheimer disease
- (2011) Christiane Reitz et al. Nature Reviews Neurology
- Neuropathologic features associated with Alzheimer disease diagnosis: Age matters
- (2011) L. E. Middleton et al. NEUROLOGY
- Autosomal-dominant Alzheimer's disease: a review and proposal for the prevention of Alzheimer's disease
- (2011) Randall J Bateman et al. Alzheimers Research & Therapy
- Correlating familial Alzheimer’s disease gene mutations with clinical phenotype
- (2010) Natalie S Ryan et al. Biomarkers in Medicine
- Carbon-11-Pittsburgh compound B positron emission tomography imaging of amyloid deposition in presenilin 1 mutation carriers
- (2010) William D. Knight et al. BRAIN
- Increased metabolic vulnerability in early-onset Alzheimer’s disease is not related to amyloid burden
- (2010) Gil D. Rabinovici et al. BRAIN
- Prevalence and causes of young onset dementia in an English health district
- (2010) Edward Renvoize et al. INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY
- Early-onset versus late-onset Alzheimer's disease: the case of the missing APOE ɛ4 allele
- (2010) Wiesje M van der Flier et al. LANCET NEUROLOGY
- Age, Neuropathology, and Dementia
- (2009) George M. Savva et al. NEW ENGLAND JOURNAL OF MEDICINE
- A Recessive Mutation in the APP Gene with Dominant-Negative Effect on Amyloidogenesis
- (2009) G. Di Fede et al. SCIENCE
- Role of the Neuropathology of Alzheimer Disease in Dementia in the Oldest-Old
- (2008) Vahram Haroutunian et al. ARCHIVES OF NEUROLOGY
- Clearance mechanisms of Alzheimer's amyloid-β peptide: implications for therapeutic design and diagnostic tests
- (2008) K A Bates et al. MOLECULAR PSYCHIATRY
- INTRAFAMILIAL DIVERSITY OF PHENOTYPE ASSOCIATED WITH APP DUPLICATION
- (2008) I. Guyant-Marechal et al. NEUROLOGY
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