Physical Activity, APOE Genotype, and Cognitive Decline: Exploring Gene-Environment Interactions in the UK Biobank

UK Biobank, big data, and the consequences of non-representativeness

(2019) Katherine M Keyes et al.   LANCET

Physical activity modifies the influence of apolipoprotein E ε4 allele and type 2 diabetes on dementia and cognitive impairment among older Mexican Americans

(2018) I-Fan Shih et al.   Alzheimers & Dementia

Cognitive function and the agreement between self-reported and accelerometer-accessed physical activity

(2018) Florian Herbolsheimer et al.   BMC Geriatrics

Characterizing the Preclinical Stages of Alzheimer's Disease and the Prospect of Presymptomatic Intervention

(2018) Richard J. Caselli et al.   JOURNAL OF ALZHEIMERS DISEASE

Information bias in measures of self-reported physical activity

(2018) Stephanie Folley et al.   INTERNATIONAL JOURNAL OF OBESITY

The UK Biobank resource with deep phenotyping and genomic data

(2018) Clare Bycroft et al.   NATURE

Lifestyle interventions to prevent cognitive impairment, dementia and Alzheimer disease

(2018) Miia Kivipelto et al.   Nature Reviews Neurology

Sleep Disturbance, Cognitive Decline, and Dementia: A Review

(2017) Mark Wu et al.   SEMINARS IN NEUROLOGY

Alzheimer disease genetic risk factorAPOEe4 and cognitive abilities in 111,739 UK Biobank participants

(2016) Donald M. Lyall et al.   AGE AND AGEING

Cognitive Test Scores in UK Biobank: Data Reduction in 480,416 Participants and Longitudinal Stability in 20,346 Participants

(2016) Donald M. Lyall et al.   PLoS One

Intensity Thresholds on Raw Acceleration Data: Euclidean Norm Minus One (ENMO) and Mean Amplitude Deviation (MAD) Approaches

(2016) Kishan Bakrania et al.   PLoS One

Estimation of Physical Activity Energy Expenditure during Free-Living from Wrist Accelerometry in UK Adults

(2016) Tom White et al.   PLoS One

Leisure-time physical activity from mid- to late life, body mass index, and risk of dementia

(2015) Anna-Maija Tolppanen et al.   Alzheimers & Dementia

Innovative Research Exploring the Effects of Physical Activity and Genetics on Cognitive Performance in Community-Based Older Adults

(2015) Jennifer L. Etnier et al.   JOURNAL OF AGING AND PHYSICAL ACTIVITY

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

Does physical activity prevent cognitive decline and dementia?: A systematic review and meta-analysis of longitudinal studies

(2014) Sarah J Blondell et al.   BMC PUBLIC HEALTH

0148 Using the UK Biobank study to estimate occupational causes of chronic disease: comparability with the UK national population and adjustment for bias

(2014) Sally Hutchings et al.   OCCUPATIONAL AND ENVIRONMENTAL MEDICINE

Physical Activity and Cognitive Trajectories in Cognitively Normal Adults

(2013) Rachel Pizzie et al.   ALZHEIMER DISEASE & ASSOCIATED DISORDERS

Normal Cognitive Aging

(2013) Caroline N. Harada et al.   CLINICS IN GERIATRIC MEDICINE

APOE Genotype and Cognitive Change in Young, Middle-Aged, and Older Adults Living in the Community

(2013) D. Bunce et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Apolipoprotein E gene, environmental risk factors, and their interactions in dementia among seniors

(2012) Xiangfei Meng et al.   INTERNATIONAL JOURNAL OF GERIATRIC PSYCHIATRY

A genome-wide association study implicates the APOE locus in nonpathological cognitive ageing

(2012) G Davies et al.   MOLECULAR PSYCHIATRY

Total daily physical activity and the risk of AD and cognitive decline in older adults

(2012) A.S. Buchman et al.   NEUROLOGY

Physical Activity, Physical Function, and Incident Dementia in Elderly Men: The Honolulu-Asia Aging Study

(2011) D. R. Taaffe et al.   JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

Prevalence of Apolipoprotein E4 Genotype and Homozygotes (APOE e4/4) among Patients Diagnosed with Alzheimer’s Disease: A Systematic Review and Meta-Analysis

(2011) Alex Ward et al.   NEUROEPIDEMIOLOGY

Robust relationship inference in genome-wide association studies

(2010) Ani Manichaikul et al.   BIOINFORMATICS

Effect of Apolipoprotein E epsilon4 on the association between health behaviors and cognitive function in late midlife

(2010) Severine Sabia et al.   Molecular Neurodegeneration

Gene–environment-wide association studies: emerging approaches

(2010) Duncan Thomas   NATURE REVIEWS GENETICS

Interactive effects of physical activity and APOE-ε4 on BOLD semantic memory activation in healthy elders

(2010) J. Carson Smith et al.   NEUROIMAGE

Apolipoprotein E: Implications for AD neurobiology, epidemiology and risk assessment

(2009) Hyman M. Schipper   NEUROBIOLOGY OF AGING

Longitudinal Modeling of Age-Related Memory Decline and theAPOEε4 Effect

(2009) Richard J. Caselli et al.   NEW ENGLAND JOURNAL OF MEDICINE

Midlife activity predicts risk of dementia in older male twin pairs

(2008) Michelle C. Carlson et al.   Alzheimers & Dementia

Exercise, APOE, and working memory: MEG and behavioral evidence for benefit of exercise in epsilon4 carriers

(2008) Sean P. Deeny et al.   BIOLOGICAL PSYCHOLOGY

Physical, social and productive leisure activities, cognitive decline and interaction with APOE-ε4 genotype in Chinese older adults

(2008) Matthew Niti et al.   INTERNATIONAL PSYCHOGERIATRICS

Apolipoprotein E ɛ4 magnifies lifestyle risks for dementia: a population-based study

(2008) Miia Kivipelto et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE