Selective motor activation in organelle transport along axons

Calcineurin and huntingtin form a calcium-sensing machinery that directs neurotrophic signals to the nucleus

(2022) Chiara Scaramuzzino et al.   Science Advances

RUFY3 links Arl8b and JIP4-Dynein complex to regulate lysosome size and positioning

(2022) Gaurav Kumar et al.   Nature Communications

RUFY3 and RUFY4 are ARL8 effectors that promote coupling of endolysosomes to dynein-dynactin

(2022) Tal Keren-Kaplan et al.   Nature Communications

Metaxins are core components of mitochondrial transport adaptor complexes

(2021) Yinsuo Zhao et al.   Nature Communications

Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes

(2021) C. Alexander Boecker et al.   CURRENT BIOLOGY

Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C

(2021) Joseph C. Roney et al.   DEVELOPMENTAL CELL

Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons

(2021) Swetha Gowrishankar et al.   MOLECULAR BIOLOGY OF THE CELL

Rab2 drives axonal transport of dense core vesicles and lysosomal organelles

(2021) Viktor Karlovich Lund et al.   Cell Reports

Post-Golgi carriers, not lysosomes, confer lysosomal properties to pre-degradative organelles in normal and dystrophic axons

(2021) Pearl P.Y. Lie et al.   Cell Reports

C9orf72-derived arginine-containing dipeptide repeats associate with axonal transport machinery and impede microtubule-based motility

(2021) Laura Fumagalli et al.   Science Advances

Coordinated bi-directional trafficking of synaptic vesicle and active zone proteins in peripheral nerves

(2021) Judyta K. Juranek et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Sequential dynein effectors regulate axonal autophagosome motility in a maturation-dependent pathway

(2021) Sydney E. Cason et al.   JOURNAL OF CELL BIOLOGY

Specific KIF1A–adaptor interactions control selective cargo recognition

(2021) Jessica J.A. Hummel et al.   JOURNAL OF CELL BIOLOGY

FHL2 anchors mitochondria to actin and adapts mitochondrial dynamics to glucose supply

(2021) Himanish Basu et al.   JOURNAL OF CELL BIOLOGY

Clathrin packets move in slow axonal transport and deliver functional payloads to synapses

(2021) Archan Ganguly et al.   NEURON

Mitochondrial adaptor TRAK2 activates and functionally links opposing kinesin and dynein motors

(2021) Adam R. Fenton et al.   Nature Communications

The Novel KIF1A Missense Variant (R169T) Strongly Reduces Microtubule Stimulated ATPase Activity and Is Associated With NESCAV Syndrome

(2021) Cinthia Aguilera et al.   Frontiers in Neuroscience

Microtubule dynamics influence the retrograde biased motility of kinesin-4 motor teams in neuronal dendrites

(2021) Erin M. Masucci et al.   MOLECULAR BIOLOGY OF THE CELL

Cytoplasmic dynein-1 cargo diversity is mediated by the combinatorial assembly of FTS–Hook–FHIP complexes

(2021) Jenna R Christensen et al.   eLife

A Combinatorial MAP Code Dictates Polarized Microtubule Transport

(2020) Brigette Y. Monroy et al.   DEVELOPMENTAL CELL

SKIP ‐ HOPS recruits TBC 1D15 for a Rab7‐to‐Arl8b identity switch to control late endosome transport

(2020) Marlieke LM Jongsma et al.   EMBO JOURNAL

PTPN23 binds the dynein adaptor BICD1 and is required for endocytic sorting of neurotrophin receptors

(2020) Marta I. Budzinska et al.   JOURNAL OF CELL SCIENCE

Smart motors and cargo steering drive kinesin-mediated selective transport

(2020) Alec T. Nabb et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

The tubulin code and its role in controlling microtubule properties and functions

(2020) Carsten Janke et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Measuring mRNA translation in neuronal processes and somata by tRNA-FRET

(2020) Bella Koltun et al.   NUCLEIC ACIDS RESEARCH

Miro: A molecular switch at the center of mitochondrial regulation

(2020) Emily L. Eberhardt et al.   PROTEIN SCIENCE

Structural Basis for Rab8a Recruitment of RILPL2 via LRRK2 Phosphorylation of Switch 2

(2020) Dieter Waschbüsch et al.   STRUCTURE

Activation and Regulation of Cytoplasmic Dynein

(2020) John T. Canty et al.   TRENDS IN BIOCHEMICAL SCIENCES

A Rare KIF1A Missense Mutation Enhances Synaptic Function and Increases Seizure Activity

(2020) Yi Guo et al.   Frontiers in Genetics

The Dynein Adaptor RILP Controls Neuronal Autophagosome Biogenesis, Transport, and Clearance

(2020) Noopur V. Khobrekar et al.   DEVELOPMENTAL CELL

Dynactin p150 promotes processive motility of DDB complexes by minimizing diffusional behavior of dynein

(2020) Qingzhou Feng et al.   MOLECULAR BIOLOGY OF THE CELL

LIS1 promotes the formation of activated cytoplasmic dynein-1 complexes

(2020) Zaw Min Htet et al.   NATURE CELL BIOLOGY

Lis1 activates dynein motility by modulating its pairing with dynactin

(2020) Mohamed M. Elshenawy et al.   NATURE CELL BIOLOGY

Pac1/LIS1 stabilizes an uninhibited conformation of dynein to coordinate its localization and activity

(2020) Matthew G. Marzo et al.   NATURE CELL BIOLOGY

These motors were made for walking

(2020) Byron Hunter et al.   PROTEIN SCIENCE

Mutations in the KIF21B kinesin gene cause neurodevelopmental disorders through imbalanced canonical motor activity

(2020) Laure Asselin et al.   Nature Communications

Presynaptic APP levels and synaptic homeostasis are regulated by Akt phosphorylation of Huntingtin

(2020) Julie Bruyère et al.   eLife

Finding order in slow axonal transport

(2020) Subhojit Roy   CURRENT OPINION IN NEUROBIOLOGY

Assembly of the presynaptic active zone

(2020) Javier Emperador-Melero et al.   CURRENT OPINION IN NEUROBIOLOGY

The Tubulin Code in Microtubule Dynamics and Information Encoding

(2020) Antonina Roll-Mecak   DEVELOPMENTAL CELL

A Conserved Role for Vezatin Proteins in Cargo-Specific Regulation of Retrograde Axonal Transport

(2020) Michael A. Spinner et al.   GENETICS

Genetic and functional analysis of KIF5A variants in Japanese patients with sporadic amyotrophic lateral sclerosis.

(2020) Ryoichi Nakamura et al.   NEUROBIOLOGY OF AGING

Truncated Tau Induces Mitochondrial Transport Failure Through the Impairment of TRAK2 Protein and Bioenergetics Decline in Neuronal Cells

(2020) Rodrigo A. Quintanilla et al.   Frontiers in Cellular Neuroscience

Mitochondria-adaptor TRAK1 promotes kinesin-1 driven transport in crowded environments

(2020) Verena Henrichs et al.   Nature Communications

Synaptic Vesicle Precursors and Lysosomes Are Transported by Different Mechanisms in the Axon of Mammalian Neurons

(2020) Raffaella De Pace et al.   Cell Reports

How Kinesin-1 Utilize the Energy of Nucleotide: The Conformational Changes and Mechanochemical Coupling in the Unidirectional Motion of Kinesin-1

(2020) Jingyu Qin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Spastin depletion increases tubulin polyglutamylation and impairs kinesin-mediated neuronal transport, leading to working and associative memory deficits

(2020) André T. Lopes et al.   PLOS BIOLOGY

Anterograde Axonal Transport in Neuronal Homeostasis and Disease

(2020) Laurent Guillaud et al.   Frontiers in Molecular Neuroscience

Distinct retrograde microtubule motor sets drive early and late endosome transport

(2020) Giulia Villari et al.   EMBO JOURNAL

Binding and transport of SFPQ-RNA granules by KIF5A/KLC1 motors promotes axon survival

(2020) Yusuke Fukuda et al.   JOURNAL OF CELL BIOLOGY

Stable tug-of-war between kinesin-1 and cytoplasmic dynein upon different ATP and roadblock concentrations

(2020) Gina A. Monzon et al.   JOURNAL OF CELL SCIENCE

The functional organization of axonal mRNA transport and translation

(2020) Irene Dalla Costa et al.   NATURE REVIEWS NEUROSCIENCE

The mechanism of kinesin inhibition by kinesin-binding protein

(2020) Joseph Atherton et al.   eLife

ARL8 Relieves SKIP Autoinhibition to Enable Coupling of Lysosomes to Kinesin-1

(2020) Tal Keren-Kaplan et al.   CURRENT BIOLOGY

Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

(2019) Jean-Michel Cioni et al.   CELL

Kinesin-3 Responds to Local Microtubule Dynamics to Target Synaptic Cargo Delivery to the Presynapse

(2019) Pedro Guedes-Dias et al.   CURRENT BIOLOGY

A transient helix in the disordered region of dynein light intermediate chain links the motor to structurally diverse adaptors for cargo transport

(2019) Ricardo Celestino et al.   PLOS BIOLOGY

Load‐dependent detachment kinetics plays a key role in bidirectional cargo transport by kinesin and dynein

(2019) Kazuka G. Ohashi et al.   TRAFFIC

Dynein activators and adaptors at a glance

(2019) Mara A. Olenick et al.   JOURNAL OF CELL SCIENCE

Maturation and Clearance of Autophagosomes in Neurons Depends on a Specific Cysteine Protease Isoform, ATG-4.2

(2019) Sarah E. Hill et al.   DEVELOPMENTAL CELL

Quantifying Protein Copy Number in Super-Resolution Using an Imaging-Invariant Calibration

(2019) Francesca Cella Zanacchi et al.   BIOPHYSICAL JOURNAL

The light-sensitive dimerizer zapalog reveals distinct modes of immobilization for axonal mitochondria

(2019) Amos Gutnick et al.   NATURE CELL BIOLOGY

Hook3 is a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and KIF1C

(2019) Agnieszka A. Kendrick et al.   JOURNAL OF CELL BIOLOGY

PTPN21 and Hook3 relieve KIF1C autoinhibition and activate intracellular transport

(2019) Nida Siddiqui et al.   Nature Communications

Neuronal Soma-Derived Degradative Lysosomes Are Continuously Delivered to Distal Axons to Maintain Local Degradation Capacity

(2019) Tamar Farfel-Becker et al.   Cell Reports

Cargo adaptors regulate stepping and force generation of mammalian dynein–dynactin

(2019) Mohamed M. Elshenawy et al.   Nature Chemical Biology

Disease-associated mutations hyperactivate KIF1A motility and anterograde axonal transport of synaptic vesicle precursors

(2019) Kyoko Chiba et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Going Too Far Is the Same as Falling Short†: Kinesin-3 Family Members in Hereditary Spastic Paraplegia

(2019) Dominik R. Gabrych et al.   Frontiers in Cellular Neuroscience

The adaptor proteins HAP1a and GRIP1 collaborate to activate the kinesin-1 isoform KIF5C

(2019) Alison E. Twelvetrees et al.   JOURNAL OF CELL SCIENCE

A novel strategy to visualize vesicle‐bound kinesins reveals the diversity of kinesin‐mediated transport

(2019) Rui Yang et al.   TRAFFIC

The p75 Neurotrophin Receptor Facilitates TrkB Signaling and Function in Rat Hippocampal Neurons

(2019) Juan P. Zanin et al.   Frontiers in Cellular Neuroscience

Structural characterization of the RH1-LZI tandem of JIP3/4 highlights RH1 domains as a cytoskeletal motor-binding motif

(2019) Fernando Vilela et al.   Scientific Reports

Activity-Dependent Nucleation of Dynamic Microtubules at Presynaptic Boutons Controls Neurotransmission

(2019) Xiaoyi Qu et al.   CURRENT BIOLOGY

Neuronal autophagy and intercellular regulation of homeostasis in the brain

(2018) Aditi Kulkarni et al.   CURRENT OPINION IN NEUROBIOLOGY

Polarity of Neuronal Membrane Traffic Requires Sorting of Kinesin Motor Cargo during Entry into Dendrites by a Microtubule-Associated Septin

(2018) Eva P. Karasmanis et al.   DEVELOPMENTAL CELL

Miro proteins coordinate microtubule‐ and actin‐dependent mitochondrial transport and distribution

(2018) Guillermo López‐Doménech et al.   EMBO JOURNAL

Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons

(2018) Xiu-Tang Cheng et al.   JOURNAL OF CELL BIOLOGY

The cytoplasmic dynein transport machinery and its many cargoes

(2018) Samara L. Reck-Peterson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

(2018) Danielle A. Grotjahn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene

(2018) Aude Nicolas et al.   NEURON

A conserved interaction of the dynein light intermediate chain with dynein-dynactin effectors necessary for processivity

(2018) In-Gyun Lee et al.   Nature Communications

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

(2018) Danielle A. Grotjahn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

A novel mouse model carrying a human cytoplasmic dynein mutation shows motor behavior deficits consistent with Charcot-Marie-Tooth type 2O disease

(2018) Thywill T. Sabblah et al.   Scientific Reports

Regulation of KIF1A-Driven Dense Core Vesicle Transport: Ca 2+ /CaM Controls DCV Binding and Liprin-α/TANC2 Recruits DCVs to Postsynaptic Sites

(2018) Riccardo Stucchi et al.   Cell Reports

Recruitment of two dyneins to an mRNA-dependent Bicaudal D transport complex

(2018) Thomas E Sladewski et al.   eLife

Neuronal endosomes to lysosomes: A journey to the soma

(2018) Vineet Vinay Kulkarni et al.   JOURNAL OF CELL BIOLOGY

Cryo-EM shows how dynactin recruits two dyneins for faster movement

(2018) Linas Urnavicius et al.   NATURE

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles

(2018) Anela Vukoja et al.   NEURON

Severing enzymes amplify microtubule arrays through lattice GTP-tubulin incorporation

(2018) Annapurna Vemu et al.   SCIENCE

Insights into Kinesin-1 Activation from the Crystal Structure of KLC2 Bound to JIP3

(2018) Joseph J.B. Cockburn et al.   STRUCTURE

The small G protein Arl8 contributes to lysosomal function and long-range axonal transport in Drosophila

(2018) Cláudia Rosa-Ferreira et al.   Biology Open

TUBA1A mutations identified in lissencephaly patients dominantly disrupt neuronal migration and impair dynein activity

(2018) Jayne Aiken et al.   HUMAN MOLECULAR GENETICS

Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons

(2018) Mara A. Olenick et al.   JOURNAL OF CELL BIOLOGY

Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology

(2017) Swetha Gowrishankar et al.   JOURNAL OF CELL BIOLOGY

Molecular mechanism of dynein recruitment to kinetochores by the Rod–Zw10–Zwilch complex and Spindly

(2017) José B. Gama et al.   JOURNAL OF CELL BIOLOGY

HAP1 Is Required for Endocytosis and Signalling of BDNF and Its Receptors in Neurons

(2017) Yoon Lim et al.   MOLECULAR NEUROBIOLOGY

Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK -Deficient Mice

(2017) Emilie Giaime et al.   NEURON

Mitostasis in Neurons: Maintaining Mitochondria in an Extended Cellular Architecture

(2017) Thomas Misgeld et al.   NEURON

Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport

(2017) Roderick P. Tas et al.   NEURON

BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon

(2017) Ginny G. Farías et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes

(2017) Rose Willett et al.   Nature Communications

Capture of Dense Core Vesicles at Synapses by JNK-Dependent Phosphorylation of Synaptotagmin-4

(2017) Vinita Bharat et al.   Cell Reports

Active zone proteins are transported via distinct mechanisms regulated by Par-1 kinase

(2017) Kara R. Barber et al.   PLoS Genetics

UNC-16/JIP3 regulates early events in synaptic vesicle protein trafficking via LRK-1/LRRK2 and AP complexes

(2017) Bikash Choudhary et al.   PLoS Genetics

SNAPIN is critical for lysosomal acidification and autophagosome maturation in macrophages

(2016) Bo Shi et al.   Autophagy

Arf6 and the 5'phosphatase of synaptojanin 1 regulate autophagy in cone photoreceptors

(2016) Ashley A. George et al.   BIOESSAYS

Dynein Clusters into Lipid Microdomains on Phagosomes to Drive Rapid Transport toward Lysosomes

(2016) Ashim Rai et al.   CELL

Three-Step Model for Polarized Sorting of KIF17 into Dendrites

(2016) Mariella A. Franker et al.   CURRENT BIOLOGY

Kinesin-Binding Protein Controls Microtubule Dynamics and Cargo Trafficking by Regulating Kinesin Motor Activity

(2016) Josta T. Kevenaar et al.   CURRENT BIOLOGY

Tyrosination of α‐tubulin controls the initiation of processive dynein–dynactin motility

(2016) Richard J McKenney et al.   EMBO JOURNAL

Microtubule-binding protein doublecortin-like kinase 1 (DCLK1) guides kinesin-3-mediated cargo transport to dendrites

(2016) J. Lipka et al.   EMBO JOURNAL

Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction

(2016) Mara A. Olenick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The position of lysosomes within the cell determines their luminal pH

(2016) Danielle E. Johnson et al.   JOURNAL OF CELL BIOLOGY

Assembly and activation of dynein–dynactin by the cargo adaptor protein Hook3

(2016) Courtney M. Schroeder et al.   JOURNAL OF CELL BIOLOGY

Activity-Dependent Regulation of Distinct Transport and Cytoskeletal Remodeling Functions of the Dendritic Kinesin KIF21B

(2016) Amy E. Ghiretti et al.   NEURON

The light chains of kinesin-1 are autoinhibited

(2016) Yan Y. Yip et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses

(2016) Shinsuke Niwa et al.   Cell Reports

α-Tubulin Tyrosination and CLIP-170 Phosphorylation Regulate the Initiation of Dynein-Driven Transport in Neurons

(2016) Jeffrey J. Nirschl et al.   Cell Reports

BORC Functions Upstream of Kinesins 1 and 3 to Coordinate Regional Movement of Lysosomes along Different Microtubule Tracks

(2016) Carlos M. Guardia et al.   Cell Reports

Phosphoproteomics reveals that Parkinson's disease kinase LRRK2 regulates a subset of Rab GTPases

(2016) Martin Steger et al.   eLife

BORC, a Multisubunit Complex that Regulates Lysosome Positioning

(2015) Jing Pu et al.   DEVELOPMENTAL CELL

Novel Mutations in the DYNC1H1 Tail Domain Refine the Genetic and Clinical Spectrum of Dyneinopathies

(2015) Kristien Peeters et al.   HUMAN MUTATION

JIP3 Activates Kinesin-1 Motility to Promote Axon Elongation

(2015) Dana Watt et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Axonal autophagosomes recruit dynein for retrograde transport through fusion with late endosomes

(2015) Xiu-Tang Cheng et al.   JOURNAL OF CELL BIOLOGY

Characterizing KIF16B in Neurons Reveals a Novel Intramolecular "Stalk Inhibition" Mechanism That Regulates Its Capacity to Potentiate the Selective Somatodendritic Localization of Early Endosomes

(2015) A. Farkhondeh et al.   JOURNAL OF NEUROSCIENCE

Discovery of a vezatin-like protein for dynein-mediated early endosome transport

(2015) Xuanli Yao et al.   MOLECULAR BIOLOGY OF THE CELL

Effects of α-Tubulin K40 Acetylation and Detyrosination on Kinesin-1 Motility in a Purified System

(2014) Neha Kaul et al.   BIOPHYSICAL JOURNAL

LC3 Binding to the Scaffolding Protein JIP1 Regulates Processive Dynein-Driven Transport of Autophagosomes

(2014) Meng-meng Fu et al.   DEVELOPMENTAL CELL

The Regulation of Autophagosome Dynamics by Huntingtin and HAP1 Is Disrupted by Expression of Mutant Huntingtin, Leading to Defective Cargo Degradation

(2014) Y. C. Wong et al.   JOURNAL OF NEUROSCIENCE

Bidirectional cargo transport: moving beyond tug of war

(2014) William O. Hancock   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

(2014) R. J. McKenney et al.   SCIENCE

Cytoplasmic dynein: a key player in neurodegenerative and neurodevelopmental diseases

(2014) Xiang-Jun Chen et al.   Science China-Life Sciences

siRNA screen of ES cell-derived motor neurons identifies novel regulators of tetanus toxin and neurotrophin receptor trafficking

(2014) Marco Terenzio et al.   Frontiers in Cellular Neuroscience

Neuronal Signaling through Endocytosis

(2014) K. E. Cosker et al.   Cold Spring Harbor Perspectives in Biology

Molecular Adaptations Allow Dynein to Generate Large Collective Forces inside Cells

(2013) Arpan K. Rai et al.   CELL

JIP1 regulates the directionality of APP axonal transport by coordinating kinesin and dynein motors

(2013) Meng-meng Fu et al.   JOURNAL OF CELL BIOLOGY

The Kinesin-2 Family Member KIF3C Regulates Microtubule Dynamics and Is Required for Axon Growth and Regeneration

(2013) L. F. Gumy et al.   JOURNAL OF NEUROSCIENCE

TRAK/Milton Motor-Adaptor Proteins Steer Mitochondrial Trafficking to Axons and Dendrites

(2013) Myrrhe van Spronsen et al.   NEURON

JNK-Interacting Protein 3 Mediates the Retrograde Transport of Activated c-Jun N-Terminal Kinase and Lysosomes

(2013) Catherine M. Drerup et al.   PLoS Genetics

Neuropeptide Delivery to Synapses by Long-Range Vesicle Circulation and Sporadic Capture

(2012) Man Yan Wong et al.   CELL

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

Multiple modes of cytoplasmic dynein regulation

(2012) Richard B. Vallee et al.   NATURE CELL BIOLOGY

Network Organization of the Huntingtin Proteomic Interactome in Mammalian Brain

(2012) Dyna I. Shirasaki et al.   NEURON

Phosphorylation-regulated axonal dependent transport of syntaxin 1 is mediated by a Kinesin-1 adapter

(2012) J. J. E. Chua et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Force measurements on cargoes in living cells reveal collective dynamics of microtubule motors

(2012) A. G. Hendricks et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Snapin Recruits Dynein to BDNF-TrkB Signaling Endosomes for Retrograde Axonal Transport and Is Essential for Dendrite Growth of Cortical Neurons

(2012) Bing Zhou et al.   Cell Reports

Sunday Driver/JIP3 binds kinesin heavy chain directly and enhances its motility

(2011) Faneng Sun et al.   EMBO JOURNAL

The Caenorhabditis elegans JIP3 Protein UNC-16 Functions As an Adaptor to Link Kinesin-1 with Cytoplasmic Dynein

(2011) M. Arimoto et al.   JOURNAL OF NEUROSCIENCE

The Structure of the Kinesin-1 Motor-Tail Complex Reveals the Mechanism of Autoinhibition

(2011) H. Y. K. Kaan et al.   SCIENCE

Motor Coordination via a Tug-of-War Mechanism Drives Bidirectional Vesicle Transport

(2010) Adam G. Hendricks et al.   CURRENT BIOLOGY

Kinesins at a glance

(2010) S. A. Endow et al.   JOURNAL OF CELL SCIENCE

An Arf-like Small G Protein, ARL-8, Promotes the Axonal Transport of Presynaptic Cargoes by Suppressing Vesicle Aggregation

(2010) Matthew P. Klassen et al.   NEURON

Snapin-Regulated Late Endosomal Transport Is Critical for Efficient Autophagy-Lysosomal Function in Neurons

(2010) Qian Cai et al.   NEURON

Delivery of GABAARs to Synapses Is Mediated by HAP1-KIF5 and Disrupted by Mutant Huntingtin

(2010) Alison E. Twelvetrees et al.   NEURON

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

(2010) Nobutaka Hirokawa et al.   NEURON

ARF6 Interacts with JIP4 to Control a Motor Switch Mechanism Regulating Endosome Traffic in Cytokinesis

(2009) Guillaume Montagnac et al.   CURRENT BIOLOGY

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Docking of Axonal Mitochondria by Syntaphilin Controls Their Mobility and Affects Short-Term Facilitation

(2008) Jian-Sheng Kang et al.   CELL

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

(2008) Emilie Colin et al.   EMBO JOURNAL

KIF1Bβ- and KIF1A-mediated axonal transport of presynaptic regulator Rab3 occurs in a GTP-dependent manner through DENN/MADD

(2008) Shinsuke Niwa et al.   NATURE CELL BIOLOGY