Load‐dependent detachment kinetics plays a key role in bidirectional cargo transport by kinesin and dynein

Motor Dynamics Underlying Cargo Transport by Pairs of Kinesin-1 and Kinesin-3 Motors

(2019) Göker Arpağ et al.   BIOPHYSICAL JOURNAL

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

(2018) Danielle A. Grotjahn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-electron tomography reveals that dynactin recruits a team of dyneins for processive motility

(2018) Danielle A. Grotjahn et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Cryo-EM shows how dynactin recruits two dyneins for faster movement

(2018) Linas Urnavicius et al.   NATURE

Differential effects of the dynein-regulatory factor Lissencephaly-1 on processive dynein-dynactin motility

(2017) Pedro A. Gutierrez et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Intraflagellar transport velocity is governed by the number of active KIF17 and KIF3AB motors and their motility properties under load

(2017) Bojan Milic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tug-of-war between two elastically coupled molecular motors: a case study on force generation and force balance

(2017) Mehmet Can Uçar et al.   Soft Matter

The Kinesin-1 Chemomechanical Cycle: Stepping Toward a Consensus

(2016) William O. Hancock   BIOPHYSICAL JOURNAL

Hook Adaptors Induce Unidirectional Processive Motility by Enhancing the Dynein-Dynactin Interaction

(2016) Mara A. Olenick et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The mammalian dynein–dynactin complex is a strong opponent to kinesin in a tug-of-war competition

(2016) Vladislav Belyy et al.   NATURE CELL BIOLOGY

Importance of anisotropy in detachment rates for force production and cargo transport by a team of motor proteins

(2016) Anjneya Takshak et al.   PROTEIN SCIENCE

How Dynein Moves Along Microtubules

(2016) Gira Bhabha et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mechanism and Regulation of Cytoplasmic Dynein

(2015) Michael A. Cianfrocco et al.   Annual Review of Cell and Developmental Biology

The Mechanochemical Cycle of Mammalian Kinesin-2 KIF3A/B under Load

(2015) Johan O.L. Andreasson et al.   CURRENT BIOLOGY

Control of cytoplasmic dynein force production and processivity by its C-terminal domain

(2015) Matthew P. Nicholas et al.   Nature Communications

Examining kinesin processivity within a general gating framework

(2015) Johan OL Andreasson et al.   eLife

Biophysical Challenges to Axonal Transport: Motor-Cargo Deficiencies and Neurodegeneration

(2014) Sandra E. Encalada et al.   Annual Review of Biophysics

Transport by Populations of Fast and Slow Kinesins Uncovers Novel Family-Dependent Motor Characteristics Important for In Vivo Function

(2014) Göker Arpağ et al.   BIOPHYSICAL JOURNAL

In vitroreconstitution of a highly processive recombinant human dynein complex

(2014) Max A Schlager et al.   EMBO JOURNAL

A method for multiprotein assembly in cells reveals independent action of kinesins in complex

(2014) Stephen R. Norris et al.   JOURNAL OF CELL BIOLOGY

Bidirectional cargo transport: moving beyond tug of war

(2014) William O. Hancock   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Kinesin processivity is gated by phosphate release

(2014) Bojan Milic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

(2014) R. J. McKenney et al.   SCIENCE

Molecular Adaptations Allow Dynein to Generate Large Collective Forces inside Cells

(2013) Arpan K. Rai et al.   CELL

Measuring Molecular Motor Forces In Vivo: Implications for Tug-of-War Models of Bidirectional Transport

(2012) Christina Leidel et al.   BIOPHYSICAL JOURNAL

Force-Dependent Detachment of Kinesin-2 Biases Track Switching at Cytoskeletal Filament Intersections

(2012) Harry W. Schroeder et al.   BIOPHYSICAL JOURNAL

Dynein achieves processive motion using both stochastic and coordinated stepping

(2012) Weihong Qiu et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tug-of-War in Motor Protein Ensembles Revealed with a Programmable DNA Origami Scaffold

(2012) N. D. Derr et al.   SCIENCE

Stable Kinesin and Dynein Assemblies Drive the Axonal Transport of Mammalian Prion Protein Vesicles

(2011) Sandra E. Encalada et al.   CELL

Mechanical stochastic tug-of-war models cannot explain bidirectional lipid-droplet transport

(2011) A. Kunwar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bidirectional Transport by Molecular Motors: Enhanced Processivity and Response to External Forces

(2010) Melanie J.I. Müller et al.   BIOPHYSICAL JOURNAL

Motor Coordination via a Tug-of-War Mechanism Drives Bidirectional Vesicle Transport

(2010) Adam G. Hendricks et al.   CURRENT BIOLOGY

Coordination of molecular motors: from in vitro assays to intracellular dynamics

(2010) Erika LF Holzbaur et al.   CURRENT OPINION IN CELL BIOLOGY

A cytoplasmic dynein tail mutation impairs motor processivity

(2010) Kassandra M. Ori-McKenney et al.   NATURE CELL BIOLOGY

Tug-of-war as a cooperative mechanism for bidirectional cargo transport by molecular motors

(2008) M. J. I. Muller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA