Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons

Lysosome Function and Dysfunction in Hereditary Spastic Paraplegias

(2021) Daisy Edmison et al.   Brain Sciences

De Novo Variants in MAPK8IP3 Cause Intellectual Disability with Variable Brain Anomalies

(2019) Konrad Platzer et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Lysosomal storage disorders – challenges, concepts and avenues for therapy: beyond rare diseases

(2019) André R. A. Marques et al.   JOURNAL OF CELL SCIENCE

Recurrent de novo MAPK8IP3 variants cause neurological phenotypes

(2019) Shinya Iwasawa et al.   ANNALS OF NEUROLOGY

A specific ATG-4 isoform is required for autophagic maturation and clearance in C. elegans neurons

(2019) Sarah E. Hill et al.   Autophagy

RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether

(2019) Ya-Cheng Liao et al.   CELL

CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons

(2019) Ruilin Tian et al.   NEURON

Lysosomes as dynamic regulators of cell and organismal homeostasis

(2019) Andrea Ballabio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

ToolBox: Live Imaging of intracellular organelle transport in induced pluripotent stem cell‐derived neurons

(2019) Clemens Alexander Boecker et al.   TRAFFIC

Lysosomal Dysfunction at the Centre of Parkinson’s Disease and Frontotemporal Dementia/Amyotrophic Lateral Sclerosis

(2019) Rebecca L. Wallings et al.   TRENDS IN NEUROSCIENCES

Is Parkinson’s disease a lysosomal disorder?

(2018) Andrés D Klein et al.   BRAIN

Axonal transport and maturation of lysosomes

(2018) Shawn M Ferguson   CURRENT OPINION IN NEUROBIOLOGY

Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons

(2018) Xiu-Tang Cheng et al.   JOURNAL OF CELL BIOLOGY

Degradation of dendritic cargos requires Rab7-dependent transport to somatic lysosomes

(2018) Chan Choo Yap et al.   JOURNAL OF CELL BIOLOGY

Neuronal lysosomes

(2018) Shawn M. Ferguson   NEUROSCIENCE LETTERS

Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles

(2018) Anela Vukoja et al.   NEURON

Impaired JIP3-dependent axonal lysosome transport promotes amyloid plaque pathology

(2017) Swetha Gowrishankar et al.   JOURNAL OF CELL BIOLOGY

A meta-analysis of genome-wide association studies identifies 17 new Parkinson's disease risk loci

(2017) Diana Chang et al.   NATURE GENETICS

BORC/kinesin-1 ensemble drives polarized transport of lysosomes into the axon

(2017) Ginny G. Farías et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

TFEB regulates lysosomal positioning by modulating TMEM55B expression and JIP4 recruitment to lysosomes

(2017) Rose Willett et al.   Nature Communications

Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening

(2017) Chao Wang et al.   Stem Cell Reports

Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9

(2016) Dominik Paquet et al.   NATURE

Analysis of protein-coding genetic variation in 60,706 humans

(2016) Monkol Lek et al.   NATURE

Lysosomal membrane glycoproteins bind cholesterol and contribute to lysosomal cholesterol export

(2016) Jian Li et al.   eLife

JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration

(2015) T Sato et al.   CELL DEATH AND DIFFERENTIATION

Visualizing APP and BACE-1 approximation in neurons yields insight into the amyloidogenic pathway

(2015) Utpal Das et al.   NATURE NEUROSCIENCE

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques

(2015) Swetha Gowrishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetics of Alzheimer’s Disease

(2014) Rita Guerreiro et al.   Neurotherapeutics

An Organelle Gatekeeper Function forCaenorhabditis elegansUNC-16 (JIP3) at the Axon Initial Segment

(2013) Stacey L. Edwards et al.   GENETICS

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Rapid Single-Step Induction of Functional Neurons from Human Pluripotent Stem Cells

(2013) Yingsha Zhang et al.   NEURON

A Reliable Way to Detect Endogenous Murine β-Amyloid

(2013) Andrew F. Teich et al.   PLoS One

hVps41 and VAMP7 function in direct TGN to late endosome transport of lysosomal membrane proteins

(2013) Maaike S. Pols et al.   Nature Communications

JNK-Interacting Protein 3 Mediates the Retrograde Transport of Activated c-Jun N-Terminal Kinase and Lysosomes

(2013) Catherine M. Drerup et al.   PLoS Genetics

Autophagosomes initiate distally and mature during transport toward the cell soma in primary neurons

(2012) Sandra Maday et al.   JOURNAL OF CELL BIOLOGY

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

The Human Brain in a Dish: The Promise of iPSC-Derived Neurons

(2011) Ricardo Dolmetsch et al.   CELL

Lysosomal Membrane Protein Composition, Acidic pH and Sterol Content are Regulated via a Light-Dependent Pathway in Metazoan Cells

(2011) M. G. Swetha et al.   TRAFFIC

Multicolor time-stamp reveals the dynamics and toxicity of amyloid deposition

(2011) Carlo Condello et al.   Scientific Reports

Establishment of Axon-Dendrite Polarity in Developing Neurons

(2009) Anthony P. Barnes et al.   Annual Review of Neuroscience

β-Secretase-1 elevation in transgenic mouse models of Alzheimer’s disease is associated with synaptic/axonal pathology and amyloidogenesis: implications for neuritic plaque development

(2009) Xue-Mei Zhang et al.   EUROPEAN JOURNAL OF NEUROSCIENCE