Distinct retrograde microtubule motor sets drive early and late endosome transport

Axonal precursor mi RNA s hitchhike on endosomes and locally regulate the development of neural circuits

(2020) Eloina Corradi et al.   EMBO JOURNAL

mTOR at the nexus of nutrition, growth, ageing and disease

(2020) Grace Y. Liu et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

A chemoproteomic portrait of the oncometabolite fumarate

(2019) Rhushikesh A. Kulkarni et al.   Nature Chemical Biology

Hook3 is a scaffold for the opposite-polarity microtubule-based motors cytoplasmic dynein-1 and KIF1C

(2019) Agnieszka A. Kendrick et al.   JOURNAL OF CELL BIOLOGY

PTPN21 and Hook3 relieve KIF1C autoinhibition and activate intracellular transport

(2019) Nida Siddiqui et al.   Nature Communications

Motor–cargo adaptors at the organelle–cytoskeleton interface

(2019) Jessica A Cross et al.   CURRENT OPINION IN CELL BIOLOGY

Lysosomes as dynamic regulators of cell and organismal homeostasis

(2019) Andrea Ballabio et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural elements of stromal interaction molecule function

(2018) Matthew J. Novello et al.   CELL CALCIUM

Functional diversification of the kinesin-14 family in land plants

(2018) Allison M. Gicking et al.   FEBS LETTERS

EB1 binding restricts STIM1 translocation to ER–PM junctions and regulates store-operated Ca2+entry

(2018) Chi-Lun Chang et al.   JOURNAL OF CELL BIOLOGY

The enigmatic endosome – sorting the ins and outs of endocytic trafficking

(2018) Naava Naslavsky et al.   JOURNAL OF CELL SCIENCE

The cytoplasmic dynein transport machinery and its many cargoes

(2018) Samara L. Reck-Peterson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Autophagy as a promoter of longevity: insights from model organisms

(2018) Malene Hansen et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Integrated genomics and functional validation identifies malignant cell specific dependencies in triple negative breast cancer

(2018) Nirmesh Patel et al.   Nature Communications

Here, there, and everywhere: The importance of ER membrane contact sites

(2018) Haoxi Wu et al.   SCIENCE

Vesicle trafficking pathways that direct cell migration in 3D and in vivo

(2018) Beverley J. Wilson et al.   TRAFFIC

Innate Immune Signals Induce Anterograde Endosome Transport Promoting MHC Class I Cross-Presentation

(2018) Mirjana Weimershaus et al.   Cell Reports

Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons

(2018) Mara A. Olenick et al.   JOURNAL OF CELL BIOLOGY

Molecular mechanisms of kinesin-14 motors in spindle assembly and chromosome segregation

(2017) Zhen-Yu She et al.   JOURNAL OF CELL SCIENCE

Intracellular trafficking of particles inside endosomal vesicles is regulated by particle size

(2017) Michihiko Aoyama et al.   JOURNAL OF CONTROLLED RELEASE

Size- and speed-dependent mechanical behavior in living mammalian cytoplasm

(2017) Jiliang Hu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Stop or Go? Endosome Positioning in the Establishment of Compartment Architecture, Dynamics, and Function

(2017) Jacques Neefjes et al.   TRENDS IN CELL BIOLOGY

Hitchhiking: A Non-Canonical Mode of Microtubule-Based Transport

(2017) John Salogiannis et al.   TRENDS IN CELL BIOLOGY

Multi-institutional study of nuclear KIFC1 as a biomarker of poor prognosis in African American women with triple-negative breast cancer

(2017) Angela Ogden et al.   Scientific Reports

Structural basis of small molecule ATPase inhibition of a human mitotic kinesin motor protein

(2017) Hee-Won Park et al.   Scientific Reports

Cell Biology: Kinesin-14 Backsteps to Organize Polymerizing Microtubules

(2016) Marcus Braun et al.   CURRENT BIOLOGY

Tyrosination of α‐tubulin controls the initiation of processive dynein–dynactin motility

(2016) Richard J McKenney et al.   EMBO JOURNAL

Lysosomes relax in the cellular suburbs

(2016) Swetha Gowrishankar et al.   JOURNAL OF CELL BIOLOGY

The position of lysosomes within the cell determines their luminal pH

(2016) Danielle E. Johnson et al.   JOURNAL OF CELL BIOLOGY

A molecular mechanism to regulate lysosome motility for lysosome positioning and tubulation

(2016) Xinran Li et al.   NATURE CELL BIOLOGY

Rab5 and its effector FHF contribute to neuronal polarity through dynein-dependent retrieval of somatodendritic proteins from the axon

(2016) Xiaoli Guo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Bicaudal D Family of Motor Adaptors: Linking Dynein Motility to Cargo Binding

(2016) Casper C. Hoogenraad et al.   TRENDS IN CELL BIOLOGY

PPFIA1 drives active α5β1 integrin recycling and controls fibronectin fibrillogenesis and vascular morphogenesis

(2016) Giulia Mana et al.   Nature Communications

Control of microtubule organization and dynamics: two ends in the limelight

(2015) Anna Akhmanova et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural organization of the dynein–dynactin complex bound to microtubules

(2015) Saikat Chowdhury et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Massive accumulation of luminal protease-deficient axonal lysosomes at Alzheimer’s disease amyloid plaques

(2015) Swetha Gowrishankar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural organization of the dynein–dynactin complex bound to microtubules

(2015) Saikat Chowdhury et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

HSET overexpression fuels tumor progression via centrosome clustering-independent mechanisms in breast cancer patients

(2015) Vaishali Pannu et al.   Oncotarget

Endocytosis and early endosome motility in filamentous fungi

(2014) Gero Steinberg   CURRENT OPINION IN MICROBIOLOGY

Minus-End-Directed Kinesin-14 Motors Align Antiparallel Microtubules to Control Metaphase Spindle Length

(2014) Austin J. Hepperla et al.   DEVELOPMENTAL CELL

Early endosome motility spatially organizes polysome distribution

(2014) Yujiro Higuchi et al.   JOURNAL OF CELL BIOLOGY

HookA is a novel dynein–early endosome linker critical for cargo movement in vivo

(2014) Jun Zhang et al.   JOURNAL OF CELL BIOLOGY

Hook is an adapter that coordinates kinesin-3 and dynein cargo attachment on early endosomes

(2014) Ewa Bielska et al.   JOURNAL OF CELL BIOLOGY

Reconstitution of a hierarchical +TIP interaction network controlling microtubule end tracking of dynein

(2014) Christian Duellberg et al.   NATURE CELL BIOLOGY

Autoregulatory mechanism for dynactin control of processive and diffusive dynein transport

(2014) Suvranta K. Tripathy et al.   NATURE CELL BIOLOGY

Prime movers: the mechanochemistry of mitotic kinesins

(2014) Robert A. Cross et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural basis for the extended CAP-Gly domains of p150glued binding to microtubules and the implication for tubulin dynamics

(2014) Q. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Activation of cytoplasmic dynein motility by dynactin-cargo adapter complexes

(2014) R. J. McKenney et al.   SCIENCE

Integrated regulation of motor-driven organelle transport by scaffolding proteins

(2014) Meng-meng Fu et al.   TRENDS IN CELL BIOLOGY

The Cell Biology of the Endocytic System from an Evolutionary Perspective

(2014) J. G. Wideman et al.   Cold Spring Harbor Perspectives in Biology

Dynactin functions as both a dynamic tether and brake during dynein-driven motility

(2014) Swathi Ayloo et al.   Nature Communications

Discovery and Mechanistic Study of a Small Molecule Inhibitor for Motor Protein KIFC1

(2013) Jiaquan Wu et al.   ACS Chemical Biology

The human kinesin-14 HSET tracks the tips of growing microtubules in vitro

(2013) Marcus Braun et al.   Cytoskeleton

Microtubule-dependent endosomal sorting of clathrin-independent cargo by Hook1

(2013) Lymarie Maldonado-Báez et al.   JOURNAL OF CELL BIOLOGY

Teamwork in microtubule motors

(2013) Roop Mallik et al.   TRENDS IN CELL BIOLOGY

SnapShot: Mammalian Rab Proteins in Endocytic Trafficking

(2012) Thierry Galvez et al.   CELL

New currency for old rope: from coiled-coil assemblies to α-helical barrels

(2012) Derek N Woolfson et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Acentrosomal spindle organization renders cancer cells dependent on the kinesin HSET

(2012) Julia Kleylein-Sohn et al.   JOURNAL OF CELL SCIENCE

Structure and function of endosomes in plant cells

(2012) A. L. Contento et al.   JOURNAL OF CELL SCIENCE

Endosome maturation

(2011) Jatta Huotari et al.   EMBO JOURNAL

Proteomic analysis of endocytic vesicles: Rab1a regulates motility of early endocytic vesicles

(2011) A. Mukhopadhyay et al.   JOURNAL OF CELL SCIENCE

Lysosome positioning coordinates mTORC1 activity and autophagy

(2011) Christian Poüs et al.   NATURE CELL BIOLOGY

Lysosomal positioning coordinates cellular nutrient responses

(2011) Viktor I. Korolchuk et al.   NATURE CELL BIOLOGY

In Vivo Roles of the Basic Domain of Dynactin p150 in Microtubule Plus-End Tracking and Dynein Function

(2011) Xuanli Yao et al.   TRAFFIC

SOCIC: The store-operated calcium influx complex

(2010) Luis Vaca   CELL CALCIUM

Systems survey of endocytosis by multiparametric image analysis

(2010) Claudio Collinet et al.   NATURE

Overexpression of Kinesins Mediates Docetaxel Resistance in Breast Cancer Cells

(2009) S. De et al.   CANCER RESEARCH

An EB1-Binding Motif Acts as a Microtubule Tip Localization Signal

(2009) Srinivas Honnappa et al.   CELL

The Expression of Three Genes in Primary Non-Small Cell Lung Cancer Is Associated with Metastatic Spread to the Brain

(2009) H. Grinberg-Rashi et al.   CLINICAL CANCER RESEARCH

SOAR and the polybasic STIM1 domains gate and regulate Orai channels

(2009) Joseph P. Yuan et al.   NATURE CELL BIOLOGY

Kinesin superfamily motor proteins and intracellular transport

(2009) Nobutaka Hirokawa et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

STIM1 Is a MT-Plus-End-Tracking Protein Involved in Remodeling of the ER

(2008) Ilya Grigoriev et al.   CURRENT BIOLOGY

Mechanisms to suppress multipolar divisions in cancer cells with extra centrosomes

(2008) M. Kwon et al.   GENES & DEVELOPMENT

An FTS/Hook/p107FHIP Complex Interacts with and Promotes Endosomal Clustering by the Homotypic Vacuolar Protein Sorting Complex

(2008) Lai Xu et al.   MOLECULAR BIOLOGY OF THE CELL

Exiting the Golgi complex

(2008) Maria Antonietta De Matteis et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Different Microtubule Motors Move Early and Late Endocytic Compartments

(2008) Sylvain Loubéry et al.   TRAFFIC