Active zone proteins are transported via distinct mechanisms regulated by Par-1 kinase

Deletion of endogenous Tau proteins is not detrimental in Drosophila

(2016) Sylvie Burnouf et al.   Scientific Reports

Maturation of active zone assembly byDrosophilaBruchpilot

(2016) Wernher Fouquet et al.   JOURNAL OF CELL BIOLOGY

The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

(2015) Heiko Braak et al.   BRAIN

Axonal transport declines with age in two distinct phases separated by a period of relative stability

(2015) Stefan Milde et al.   NEUROBIOLOGY OF AGING

A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones

(2015) Matthias Siebert et al.   eLife

Loss of tau results in defects in photoreceptor development and progressive neuronal degeneration inDrosophila

(2014) Bonnie J. Bolkan et al.   Developmental Neurobiology

A Presynaptic Role of Microtubule-Associated Protein 1/Futsch in Drosophila: Regulation of Active Zone Number and Neurotransmitter Release

(2014) S. Lepicard et al.   JOURNAL OF NEUROSCIENCE

The Intersection of Amyloid Beta and Tau at Synapses in Alzheimer’s Disease

(2014) Tara L. Spires-Jones et al.   NEURON

In vivo axonal transport deficits in a mouse model of fronto-temporal dementia

(2014) Tabassum Majid et al.   NeuroImage-Clinical

MARK4 and MARK3 associate with early tau phosphorylation in Alzheimer’s disease granulovacuolar degeneration bodies

(2014) Harald Lund et al.   Acta Neuropathologica Communications

CK2α regulates the transcription of BRP in Drosophila

(2013) Yogesh P. Wairkar et al.   DEVELOPMENTAL BIOLOGY

Tuberous sclerosis complex regulates Drosophila neuromuscular junction growth via the TORC2/Akt pathway

(2013) Rajalaxmi Natarajan et al.   HUMAN MOLECULAR GENETICS

Cellular and molecular mechanisms underlying presynapse formation

(2013) Poh Hui Chia et al.   JOURNAL OF CELL BIOLOGY

Axonal transport deficits and neurodegenerative diseases

(2013) Stéphanie Millecamps et al.   NATURE REVIEWS NEUROSCIENCE

The Presynaptic Active Zone

(2012) Thomas C. Südhof   NEURON

Early and Selective Impairments in Axonal Transport Kinetics of Synaptic Cargoes Induced by Soluble Amyloid β-Protein Oligomers

(2012) Yong Tang et al.   TRAFFIC

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

(2012) H. Y. Zoghbi et al.   Cold Spring Harbor Perspectives in Biology

Phospho-dependent ubiquitination and degradation of PAR-1 regulates synaptic morphology and tau-mediated Aβ toxicity in Drosophila

(2012) Seongsoo Lee et al.   Nature Communications

Loss of Axonal Mitochondria Promotes Tau-Mediated Neurodegeneration and Alzheimer's Disease–Related Tau Phosphorylation Via PAR-1

(2012) Kanae Iijima-Ando et al.   PLoS Genetics

The Coding of Temperature in the Drosophila Brain

(2011) Marco Gallio et al.   CELL

A critical role for the PAR-1/MARK-tau axis in mediating the toxic effects of Aβ on synapses and dendritic spines

(2011) Wendou Yu et al.   HUMAN MOLECULAR GENETICS

The Liprin Homology Domain Is Essential for the Homomeric Interaction of SYD-2/Liprin-  Protein in Presynaptic Assembly

(2011) H. Taru et al.   JOURNAL OF NEUROSCIENCE

The Presynaptic Dense Projection of the Caenorhabiditis elegans Cholinergic Neuromuscular Junction Localizes Synaptic Vesicles at the Active Zone through SYD-2/Liprin and UNC-10/RIM-Dependent Interactions

(2011) C. Stigloher et al.   JOURNAL OF NEUROSCIENCE

The DISABLED protein functions in CLATHRIN-mediated synaptic vesicle endocytosis and exoendocytic coupling at the active zone

(2011) F. Kawasaki et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Autism risk assessment in siblings of affected children using sex-specific genetic scores

(2011) Jerome Carayol et al.   Molecular Autism

PAR-1 promotes primary neurogenesis and asymmetric cell divisions via control of spindle orientation

(2010) J. M. Tabler et al.   DEVELOPMENT

An Arf-like Small G Protein, ARL-8, Promotes the Axonal Transport of Presynaptic Cargoes by Suppressing Vesicle Aggregation

(2010) Matthew P. Klassen et al.   NEURON

Deficits in axonal transport precede ALS symptoms in vivo

(2010) L. G. Bilsland et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Overexpression of Wild-Type Murine Tau Results in Progressive Tauopathy and Neurodegeneration

(2009) Stephanie J. Adams et al.   AMERICAN JOURNAL OF PATHOLOGY

Gene expression profiling differentiates autism case-controls and phenotypic variants of autism spectrum disorders: evidence for circadian rhythm dysfunction in severe autism

(2009) Valerie W. Hu et al.   Autism Research

A synaptic trek to autism

(2009) Thomas Bourgeron   CURRENT OPINION IN NEUROBIOLOGY

PAR-1 Phosphorylates Mind Bomb to Promote Vertebrate Neurogenesis

(2009) Olga Ossipova et al.   DEVELOPMENTAL CELL

Cyclical expression of Na+/K+-ATPase in the visual system of Drosophila melanogaster

(2009) Jolanta Górska-Andrzejak et al.   JOURNAL OF INSECT PHYSIOLOGY

Unc-51 Controls Active Zone Density and Protein Composition by Downregulating ERK Signaling

(2009) Y. P. Wairkar et al.   JOURNAL OF NEUROSCIENCE

Axonal transport and the delivery of pre-synaptic components

(2008) Ann YN Goldstein et al.   CURRENT OPINION IN NEUROBIOLOGY

Convergent evidence identifying MAP/microtubule affinity-regulating kinase 1 (MARK1) as a susceptibility gene for autism

(2008) G. Maussion et al.   HUMAN MOLECULAR GENETICS

Synaptic Defects in a Drosophila Model of Congenital Muscular Dystrophy

(2008) Y. P. Wairkar et al.   JOURNAL OF NEUROSCIENCE