Calcineurin and huntingtin form a calcium-sensing machinery that directs neurotrophic signals to the nucleus

Combined kinesin-1 and kinesin-3 activity drives axonal trafficking of TrkB receptors in Rab6 carriers

(2021) Eitan Erez Zahavi et al.   DEVELOPMENTAL CELL

Rapid whole cell imaging reveals a calcium-APPL1-dynein nexus that regulates cohort trafficking of stimulated EGF receptors

(2021) H. M. York et al.   Communications Biology

Increasing brain palmitoylation rescues behavior and neuropathology in Huntington disease mice

(2021) Amandine Virlogeux et al.   Science Advances

Huntingtin phosphorylation governs BDNF homeostasis and improves the phenotype of Mecp2 knockout mice

(2020) Yann Ehinger et al.   EMBO Molecular Medicine

Traffic signaling: new functions of huntingtin and axonal transport in neurological disease

(2020) Hélène Vitet et al.   CURRENT OPINION IN NEUROBIOLOGY

Huntington’s disease alters human neurodevelopment

(2020) Monia Barnat et al.   SCIENCE

The Rab5–Rab11 Endosomal Pathway is Required for BDNF-Induced CREB Transcriptional Regulation in Hippocampal Neurons

(2020) Andrés González-Gutiérrez et al.   JOURNAL OF NEUROSCIENCE

Axonal transport: Driving synaptic function

(2019) Pedro Guedes-Dias et al.   SCIENCE

SIPA1L2 controls trafficking and local signaling of TrkB-containing amphisomes at presynaptic terminals

(2019) Maria Andres-Alonso et al.   Nature Communications

Mechanisms of neurotrophin trafficking via Trk receptors

(2018) Emily Scott-Solomon et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Rab GTPase Function in Endosome and Lysosome Biogenesis

(2018) Lars Langemeyer et al.   TRENDS IN CELL BIOLOGY

Reconstituting Corticostriatal Network on-a-Chip Reveals the Contribution of the Presynaptic Compartment to Huntington’s Disease

(2018) Amandine Virlogeux et al.   Cell Reports

Multivesicular bodies mediate long-range retrograde NGF-TrkA signaling

(2018) Mengchen Ye et al.   eLife

Maintenance mechanisms of circuit-integrated axons

(2018) Vittoria Mariano et al.   CURRENT OPINION IN NEUROBIOLOGY

The many disguises of the signalling endosome

(2018) David Villarroel-Campos et al.   FEBS LETTERS

Membrane trafficking and cytoskeletal dynamics in neuronal function

(2018) Harold D. MacGillavry et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

Neuronal network maturation differently affects secretory vesicles and mitochondria transport in axons

(2018) Eve Moutaux et al.   Scientific Reports

Dynein activator Hook1 is required for trafficking of BDNF-signaling endosomes in neurons

(2018) Mara A. Olenick et al.   JOURNAL OF CELL BIOLOGY

NTRK fusion-positive cancers and TRK inhibitor therapy

(2018) Emiliano Cocco et al.   Nature Reviews Clinical Oncology

Differentiation between Oppositely Oriented Microtubules Controls Polarized Neuronal Transport

(2017) Roderick P. Tas et al.   NEURON

Spatial-specific functions in retrograde neuronal signalling

(2017) Eitan Erez Zahavi et al.   TRAFFIC

Retrograde transport of TrkB-containing autophagosomes via the adaptor AP-2 mediates neuronal complexity and prevents neurodegeneration

(2017) Natalia L. Kononenko et al.   Nature Communications

Retrogradely Transported TrkA Endosomes Signal Locally within Dendrites to Maintain Sympathetic Neuron Synapses

(2017) Kathryn M. Lehigh et al.   Cell Reports

EndophilinAs regulate endosomal sorting of BDNF-TrkB to mediate survival signaling in hippocampal neurons

(2017) Katja Burk et al.   Scientific Reports

There and back again: coordinated transcription, translation and transport in axonal survival and regeneration

(2016) Ozge E Tasdemir-Yilmaz et al.   CURRENT OPINION IN NEUROBIOLOGY

Amyloid precursor protein–mediated endocytic pathway disruption induces axonal dysfunction and neurodegeneration

(2016) Wei Xu et al.   JOURNAL OF CLINICAL INVESTIGATION

TRiC subunits enhance BDNF axonal transport and rescue striatal atrophy in Huntington’s disease

(2016) Xiaobei Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Flux of signalling endosomes undergoing axonal retrograde transport is encoded by presynaptic activity and TrkB

(2016) Tong Wang et al.   Nature Communications

Self-propelling vesicles define glycolysis as the minimal energy machinery for neuronal transport

(2016) María-Victoria Hinckelmann et al.   Nature Communications

Unraveling the Role of Huntingtin in Breast Cancer Metastasis

(2015) Morgane S. Thion et al.   JNCI-Journal of the National Cancer Institute

Unraveling the Role of Huntingtin in Breast Cancer Metastasis

(2015) Morgane S. Thion et al.   JNCI-Journal of the National Cancer Institute

Impaired TrkB Receptor Signaling Underlies Corticostriatal Dysfunction in Huntington’s Disease

(2014) Joshua L. Plotkin et al.   NEURON

Axonal Transport: Cargo-Specific Mechanisms of Motility and Regulation

(2014) Sandra Maday et al.   NEURON

Heterogeneous Intracellular Trafficking Dynamics of Brain-Derived Neurotrophic Factor Complexes in the Neuronal Soma Revealed by Single Quantum Dot Tracking

(2014) Anke Vermehren-Schmaedick et al.   PLoS One

Integrated regulation of motor-driven organelle transport by scaffolding proteins

(2014) Meng-meng Fu et al.   TRENDS IN CELL BIOLOGY

The Complex Ultrastructure of the Endolysosomal System

(2014) J. Klumperman et al.   Cold Spring Harbor Perspectives in Biology

Vesicular Glycolysis Provides On-Board Energy for Fast Axonal Transport

(2013) Diana Zala et al.   CELL

The Huntington disease protein accelerates breast tumour development and metastasis through ErbB2/HER2 signalling

(2013) Cristovão Moreira Sousa et al.   EMBO Molecular Medicine

β-Amyloid (Aβ) Oligomers Impair Brain-derived Neurotrophic Factor Retrograde Trafficking by Down-regulating Ubiquitin C-terminal Hydrolase, UCH-L1

(2013) Wayne W. Poon et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mutant Huntingtin Alters Retrograde Transport of TrkB Receptors in Striatal Dendrites

(2013) G. Liot et al.   JOURNAL OF NEUROSCIENCE

Ultrasensitive fluorescent proteins for imaging neuronal activity

(2013) Tsai-Wen Chen et al.   NATURE

Long-distance retrograde neurotrophic factor signalling in neurons

(2013) Anthony W. Harrington et al.   NATURE REVIEWS NEUROSCIENCE

EGF receptor trafficking: consequences for signaling and cancer

(2013) Alejandra Tomas et al.   TRENDS IN CELL BIOLOGY

Snapin Recruits Dynein to BDNF-TrkB Signaling Endosomes for Retrograde Axonal Transport and Is Essential for Dendrite Growth of Cortical Neurons

(2012) Bing Zhou et al.   Cell Reports

Isoform-Specific Dephosphorylation of Dynamin1 by Calcineurin Couples Neurotrophin Receptor Endocytosis to Axonal Growth

(2011) Daniel Bodmer et al.   NEURON

Single-molecule imaging of NGF axonal transport in microfluidic devices

(2010) Kai Zhang et al.   LAB ON A CHIP

Snapin-Regulated Late Endosomal Transport Is Critical for Efficient Autophagy-Lysosomal Function in Neurons

(2010) Qian Cai et al.   NEURON

TrkB signalling pathways in LTP and learning

(2009) Liliana Minichiello   NATURE REVIEWS NEUROSCIENCE

Altered white matter microstructure in the corpus callosum in Huntington's disease: Implications for cortical “disconnection”

(2009) H. Diana Rosas et al.   NEUROIMAGE

Genetic and pharmacological inhibition of calcineurin corrects the BDNF transport defect in Huntington's disease

(2009) Jose R Pineda et al.   Molecular Brain

Tracing the Retrograde Route in Protein Trafficking

(2008) Ludger Johannes et al.   CELL

Huntingtin phosphorylation acts as a molecular switch for anterograde/retrograde transport in neurons

(2008) Emilie Colin et al.   EMBO JOURNAL