Hesperidin and SARS-CoV-2: New Light on the Healthy Function of Citrus Fruits

In Vivo and In Vitro Evaluation of the Protective Effects of Hesperidin in Lipopolysaccharide-Induced Inflammation and Cytotoxicity of Cell

(2020) Rasha Al-Rikabi et al.   MOLECULES

Hesperetin as an adjuvant augments protective anti‐tumour immunity responses in B16F10 melanoma by stimulating cytotoxic CD8 + T cells

(2020) Shasha Jiang et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

High expression of ACE2 receptor of 2019-nCoV on the epithelial cells of oral mucosa

(2020) Hao Xu et al.   International Journal of Oral Science

Analysis of therapeutic targets for SARS-CoV-2 and discovery of potential drugs by computational methods

(2020) Canrong Wu et al.   Acta Pharmaceutica Sinica B

Citrus Flavones: An Update on Sources, Biological Functions, and Health Promoting Properties

(2020) Davide Barreca et al.   Plants-Basel

Considering the Effects of Microbiome and Diet on SARS-CoV-2 Infection: Nanotechnology Roles

(2020) Kourosh Kalantar-Zadeh et al.   ACS Nano

Oxidative Stress as Key Player in Severe Acute Respiratory Syndrome Coronavirus (SARS-CoV) Infection

(2020) Livan Delgado-Roche et al.   ARCHIVES OF MEDICAL RESEARCH

Variations of flavonoid composition and antioxidant properties among different cultivars, fruit tissues and developmental stages of citrus fruits

(2020) Chunhua Zhu et al.   CHEMISTRY & BIODIVERSITY

The ACE-2 in COVID-19: Foe or Friend?

(2020) Rinkoo Dalan et al.   HORMONE AND METABOLIC RESEARCH

Coronavirus disease 2019 (COVID-19): first indication of efficacy of Gene-Eden-VIR/Novirin in SARS-CoV-2 infection

(2020) Hanan Polansky et al.   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Indomethacin and resveratrol as potential treatment adjuncts for SARS‐CoV‐2/COVID‐19

(2020) Mark A. Marinella   INTERNATIONAL JOURNAL OF CLINICAL PRACTICE

Insights into Interactions of Flavanones with Target Human Respiratory Syncytial Virus M2-1 Protein from STD-NMR, Fluorescence Spectroscopy, and Computational Simulations

(2020) Hêmily M. R. Piva et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Functional Role of Dietary Intervention to Improve the Outcome of COVID-19: A Hypothesis of Work

(2020) Giovanni Messina et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

An investigation into the identification of potential inhibitors of SARS-CoV-2 main protease using molecular docking study

(2020) Sourav Das et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Discovery of potential multi-target-directed ligands by targeting host-specific SARS-CoV-2 structurally conserved main protease

(2020) Rakesh S. Joshi et al.   JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS

Hepatic complications of COVID‐19 and its treatment

(2020) Dandan Tian et al.   JOURNAL OF MEDICAL VIROLOGY

Impact of Nutrition and Diet on COVID-19 Infection and Implications for Kidney Health and Kidney Disease Management

(2020) Kamyar Kalantar-Zadeh et al.   JOURNAL OF RENAL NUTRITION

N-Acetylcysteine: a potential therapeutic agent for SARS-CoV-2

(2020) Francis L. Poe et al.   MEDICAL HYPOTHESES

“Quarantine during COVID-19 outbreak: changes in Diet and physical activity increase the risk of cardiovascular disease”

(2020) Anna Vittoria Mattioli et al.   NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES

Melatonin: Roles in influenza, Covid‐19, and other viral infections

(2020) George Anderson et al.   REVIEWS IN MEDICAL VIROLOGY

SARS-CoV-2 productively infects human gut enterocytes

(2020) Mart M. Lamers et al.   SCIENCE

Optimal Nutritional Status for a Well-Functioning Immune System Is an Important Factor to Protect against Viral Infections

(2020) Philip C. Calder et al.   Nutrients

Influence of Hesperidin on Systemic Immunity of Rats Following an Intensive Training and Exhausting Exercise

(2020) Patricia Ruiz-Iglesias et al.   Nutrients

Strengthening the Immune System and Reducing Inflammation and Oxidative Stress through Diet and Nutrition: Considerations during the COVID-19 Crisis

(2020) Mohammed Iddir et al.   Nutrients

Effect of Hesperidin on Cardiovascular Disease Risk Factors: The Role of Intestinal Microbiota on Hesperidin Bioavailability

(2020) Anna Mas-Capdevila et al.   Nutrients

Review of Evidence Available on Hesperidin-Rich Products as Potential Tools against COVID-19 and Hydrodynamic Cavitation-Based Extraction as a Method of Increasing Their Production

(2020) Francesco Meneguzzo et al.   Processes

Is the oral cavity relevant in SARS-CoV-2 pandemic?

(2020) David Herrera et al.   Clinical Oral Investigations

Phenolic composition, antioxidant potential and health benefits of citrus peel

(2020) Balwinder Singh et al.   FOOD RESEARCH INTERNATIONAL

Hesperetin attenuated acetaminophen-induced hepatotoxicity by inhibiting hepatocyte necrosis and apoptosis, oxidative stress and inflammatory response via upregulation of heme oxygenase-1 expression

(2020) Jingyuan Wan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Cardiac effects and toxicity of chloroquine: a short update

(2020) Kanigula Mubagwa   INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS

Extrapulmonary manifestations of COVID-19

(2020) Aakriti Gupta et al.   NATURE MEDICINE

Potential neurological effects of severe COVID-19 infection

(2020) Domenico Nuzzo et al.   NEUROSCIENCE RESEARCH

Impact of vitamins A, B, C, D, and E supplementation on improvement and mortality rate in ICU patients with coronavirus-19: a structured summary of a study protocol for a randomized controlled trial

(2020) Mohammad Taghi Beigmohammadi et al.   Trials

Intravenous high-dose vitamin C for the treatment of severe COVID-19: study protocol for a multicentre randomised controlled trial

(2020) Fang Liu et al.   BMJ Open

Targeting the Heme-Heme Oxygenase System to Prevent Severe Complications Following COVID-19 Infections

(2020) Frank A. D. T. G. Wagener et al.   Antioxidants

Antioxidant and Anti-Inflammatory Effects of Citrus Flavonoid Hesperetin: Special Focus on Neurological Disorders

(2020) Amjad Khan et al.   Antioxidants

Impact of Thiol–Disulfide Balance on the Binding of Covid-19 Spike Protein with Angiotensin-Converting Enzyme 2 Receptor

(2020) Sanchita Hati et al.   ACS Omega

Excess Ascorbate is a Chemical Stress Agent against Proteins and Cells

(2020) Maria Lehene et al.   Pharmaceuticals

Melatonin is a potential adjuvant to improve clinical outcomes in individuals with obesity and diabetes with coexistence of Covid-19

(2020) Mohamed A. El-Missiry et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Protective effects of maternal administration of curcumin and hesperidin in the rat offspring following repeated febrile seizure: Role of inflammation and TLR4

(2020) Rabi Atabaki et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mitochondria and microbiota dysfunction in COVID-19 pathogenesis

(2020) Jumana Saleh et al.   MITOCHONDRION

Tackle the free radicals damage in COVID-19

(2020) Jun Wu   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Therapeutic potential of resveratrol against emerging respiratory viral infections

(2020) Simone Filardo et al.   PHARMACOLOGY & THERAPEUTICS

Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

(2019) Tahir Muhammad et al.   Nutrients

Protective Effect of Hesperidin on the Oxidative Stress Induced by an Exhausting Exercise in Intensively Trained Rats

(2019) Sheila Estruel-Amades et al.   Nutrients

Hesperetin inhibits neuroinflammation on microglia by suppressing inflammatory cytokines and MAPK pathways

(2019) Sun Hyo Jo et al.   ARCHIVES OF PHARMACAL RESEARCH

Associations of food groups and cardiometabolic and inflammatory biomarkers – does the meal matter?

(2019) Carolina Schwedhelm et al.   BRITISH JOURNAL OF NUTRITION

Fruits, vegetables, and health: A comprehensive narrative, umbrella review of the science and recommendations for enhanced public policy to improve intake

(2019) Taylor C. Wallace et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Acute and sub-chronic oral toxicity studies of hesperidin isolated from orange peel extract in Sprague Dawley rats

(2019) Yongsheng Li et al.   REGULATORY TOXICOLOGY AND PHARMACOLOGY

The Intestinal Fate of Citrus Flavanones and Their Effects on Gastrointestinal Health

(2019) Yala Stevens et al.   Nutrients

Hesperetin relieves cisplatin-induced acute kidney injury by mitigating oxidative stress, inflammation and apoptosis

(2019) Xinliang Chen et al.   CHEMICO-BIOLOGICAL INTERACTIONS

The pharmacokinetics of flavanones

(2019) Iveta Najmanová et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Hesperidin Ameliorates Hepatic Ischemia-Reperfusion Injury in Sprague-Dawley Rats

(2019) Hyun-Kyung Park et al.   TRANSPLANTATION PROCEEDINGS

Effect of hesperetin on systemic inflammation and hepatic injury after blunt chest trauma in rats

(2019) Yasin Duran et al.   BIOTECHNIC & HISTOCHEMISTRY

Molecular Mechanism for Antibody-Dependent Enhancement of Coronavirus Entry

(2019) Yushun Wan et al.   JOURNAL OF VIROLOGY

Hesperidin improves motor disability in rat spinal cord injury through anti-inflammatory and antioxidant mechanism via Nrf-2/HO-1 pathway

(2019) Seung-Dam Heo et al.   NEUROSCIENCE LETTERS

OUP accepted manuscript

(2018)   AMERICAN JOURNAL OF CLINICAL NUTRITION

Sanguinello and Tarocco (C itrus Sinensis [L.] Osbeck): Bioactive compounds and color appearance of blood oranges

(2018) Laura Cebadera-Miranda et al.   FOOD CHEMISTRY

Contribution of Blood Orange-Based Beverages to Bioactive Compounds Intake

(2018) Fabio Licciardello et al.   Frontiers in Chemistry

Bee Venom and Hesperidin Effectively Mitigate Complete Freund’s Adjuvant-Induced Arthritis Via Immunomodulation and Enhancement of Antioxidant Defense System

(2018) Osama Ahmed   Archives of Rheumatology

Food Groups and Risk of Overweight, Obesity, and Weight Gain: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies

(2018) Sabrina Schlesinger et al.   Advances in Nutrition

Bioactive compounds in blood oranges (Citrus sinensis (L.) Osbeck): Level and intake

(2017) Biagio Fallico et al.   FOOD CHEMISTRY

Fruit and vegetable intake and the risk of cardiovascular disease, total cancer and all-cause mortality—a systematic review and dose-response meta-analysis of prospective studies

(2017) Dagfinn Aune et al.   INTERNATIONAL JOURNAL OF EPIDEMIOLOGY

Fruit, vegetable, and legume intake, and cardiovascular disease and deaths in 18 countries (PURE): a prospective cohort study

(2017) Victoria Miller et al.   LANCET

Vitamin C and Immune Function

(2017) Anitra Carr et al.   Nutrients

Mortality from different causes associated with meat, heme iron, nitrates, and nitrites in the NIH-AARP Diet and Health Study: population based cohort study

(2017) Arash Etemadi et al.   BMJ-British Medical Journal

Mortality from different causes associated with meat, heme iron, nitrates, and nitrites in the NIH-AARP Diet and Health Study: population based cohort study

(2017) Arash Etemadi et al.   BMJ-British Medical Journal

Orange juice as dietary source of antioxidants for patients with hepatitis C under antiviral therapy

(2017) Danielle Gonçalves et al.   Food & Nutrition Research

Potential Anti-inflammatory Effects of Hesperidin from the Genus Citrus

(2017) Silvia Tejada et al.   CURRENT MEDICINAL CHEMISTRY

Habitual intake of anthocyanins and flavanones and risk of cardiovascular disease in men

(2016) Aedín Cassidy et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Nut consumption and risk of cardiovascular disease, total cancer, all-cause and cause-specific mortality: a systematic review and dose-response meta-analysis of prospective studies

(2016) Dagfinn Aune et al.   BMC Medicine

Citrus flavanones naringenin and hesperetin improve antioxidant status and membrane lipid compositions in the liver of old-aged Wistar rats

(2016) Marko Miler et al.   EXPERIMENTAL GERONTOLOGY

Red ginseng and vitamin C increase immune cell activity and decrease lung inflammation induced by influenza A virus/H1N1 infection

(2016) Hyemin Kim et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Whole grain consumption and risk of cardiovascular disease, cancer, and all cause and cause specific mortality: systematic review and dose-response meta-analysis of prospective studies

(2016) Dagfinn Aune et al.   BMJ-British Medical Journal

Whole grain consumption and risk of cardiovascular disease, cancer, and all cause and cause specific mortality: systematic review and dose-response meta-analysis of prospective studies

(2016) Dagfinn Aune et al.   BMJ-British Medical Journal

100% citrus juice: Nutritional contribution, dietary benefits, and association with anthropometric measures

(2015) Gail C. Rampersaud et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Protective effects of flavonoids against microbes and toxins: The cases of hesperidin and hesperetin

(2015) Mehrdad Iranshahi et al.   LIFE SCIENCES

Molecular mechanisms behind the biological effects of hesperidin and hesperetin for the prevention of cancer and cardiovascular diseases

(2015) Ali Roohbakhsh et al.   LIFE SCIENCES

In vitro colonic catabolism of orange juice (poly)phenols

(2015) Gema Pereira-Caro et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Changes in Intake of Fruits and Vegetables and Weight Change in United States Men and Women Followed for Up to 24 Years: Analysis from Three Prospective Cohort Studies

(2015) Monica L. Bertoia et al.   PLOS MEDICINE

Orange juice (poly)phenols are highly bioavailable in humans

(2014) Gema Pereira-Caro et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Effects of Dietary Components on Cancer of the Digestive System

(2014) Sara Zanini et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

The Cellular Redox Environment Alters Antigen Presentation

(2014) Jonathan A. Trujillo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin — A mini-review

(2014) Ali Roohbakhsh et al.   LIFE SCIENCES

Antioxidant and Anti-Inflammatory Properties of the Citrus Flavonoids Hesperidin and Hesperetin: An Updated Review of their Molecular Mechanisms and Experimental Models

(2014) Hamideh Parhiz et al.   PHYTOTHERAPY RESEARCH

Flavanone metabolites decrease monocyte adhesion to TNF-α-activated endothelial cells by modulating expression of atherosclerosis-related genes

(2013) Audrey Chanet et al.   BRITISH JOURNAL OF NUTRITION

Role of angiotensin-converting enzyme 2 (ACE2) in diabetic cardiovascular complications

(2013) Vaibhav B. Patel et al.   CLINICAL SCIENCE

Red Orange: Experimental Models and Epidemiological Evidence of Its Benefits on Human Health

(2013) Giuseppe Grosso et al.   Oxidative Medicine and Cellular Longevity

Anti-inflammatory Properties of Orange Juice: Possible Favorable Molecular and Metabolic Effects

(2013) Raquel Cristina Lopes Assis Coelho et al.   PLANT FOODS FOR HUMAN NUTRITION

Vitamin C Is an Essential Factor on the Anti-viral Immune Responses through the Production of Interferon-α/β at the Initial Stage of Influenza A Virus (H3N2) Infection

(2013) Yejin Kim et al.   Immune Network

Effects of red orange juice intake on endothelial function and inflammatory markers in adult subjects with increased cardiovascular risk

(2012) Silvio Buscemi et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Citrus Flavanones: What Is Their Role in Cardiovascular Protection?

(2012) Audrey Chanet et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Dietary Antioxidants: Immunity and Host Defense

(2011) Maria A. Puertollano et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Hesperidin contributes to the vascular protective effects of orange juice: a randomized crossover study in healthy volunteers

(2010) Christine Morand et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Orange juice neutralizes the proinflammatory effect of a high-fat, high-carbohydrate meal and prevents endotoxin increase and Toll-like receptor expression

(2010) Husam Ghanim et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

NADPH oxidase-derived reactive oxygen species: involvement in vascular physiology and pathology

(2010) Adrian Manea   CELL AND TISSUE RESEARCH

Mechanisms of combined action of different chemopreventive dietary compounds

(2008) Theo M. de Kok et al.   EUROPEAN JOURNAL OF NUTRITION