Hesperetin, a Citrus Flavonoid, Attenuates LPS-Induced Neuroinflammation, Apoptosis and Memory Impairments by Modulating TLR4/NF-κB Signaling

Scutellarein Induces Fas-Mediated Extrinsic Apoptosis and G2/M Cell Cycle Arrest in Hep3B Hepatocellular Carcinoma Cells

(2019) Ha Sang Eun et al.   Nutrients

Hesperetin Confers Neuroprotection by Regulating Nrf2/TLR4/NF-κB Signaling in an Aβ Mouse Model

(2019) Muhammad Ikram et al.   MOLECULAR NEUROBIOLOGY

Nicotinamide Improves Functional Recovery via Regulation of the RAGE/JNK/NF-κB Signaling Pathway after Brain Injury

(2019) Sayed Alam et al.   Journal of Clinical Medicine

Neuroprotective effect of hesperetin and nano-hesperetin on recognition memory impairment and the elevated oxygen stress in rat model of Alzheimer’s disease

(2018) Elham kheradmand et al.   BIOMEDICINE & PHARMACOTHERAPY

Estrogen deficiency exacerbates Aβ-induced memory impairment through enhancement of neuroinflammation, amyloidogenesis and NF-ĸB activation in ovariectomized mice

(2018) Jaesuk Yun et al.   BRAIN BEHAVIOR AND IMMUNITY

PI3K/AKT/JNK/p38 signalling pathway-mediated neural apoptosis in the prefrontal cortex of mice is involved in the antidepressant-like effect of pioglitazone

(2018) Jie Li et al.   CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY

Peiminine Protects Dopaminergic Neurons from Inflammation-Induced Cell Death by Inhibiting the ERK1/2 and NF-κB Signalling Pathways

(2018) et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Acute dose of melatonin via Nrf2 dependently prevents acute ethanol-induced neurotoxicity in the developing rodent brain

(2018) Tahir Ali et al.   Journal of Neuroinflammation

Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway

(2018) Min Gi Jo et al.   MOLECULAR NEUROBIOLOGY

Emerging Roles of Astrocytes in Neuro-Vascular Unit and the Tripartite Synapse With Emphasis on Reactive Gliosis in the Context of Alzheimer’s Disease

(2018) Cai-Yun Liu et al.   Frontiers in Cellular Neuroscience

Stachys sieboldii Extract Supplementation Attenuates Memory Deficits by Modulating BDNF-CREB and Its Downstream Molecules, in Animal Models of Memory Impairment

(2018) Vijaya Ravichandran et al.   Nutrients

Ferulic Acid Rescues LPS-Induced Neurotoxicity via Modulation of the TLR4 Receptor in the Mouse Hippocampus

(2018) Shafiq Ur Rehman et al.   MOLECULAR NEUROBIOLOGY

A Natural Dietary Supplement with a Combination of Nutrients Prevents Neurodegeneration Induced by a High Fat Diet in Mice

(2018) Domenico Nuzzo et al.   Nutrients

The Ethanol Fraction of White Rose Petal Extract Abrogates Excitotoxicity-Induced Neuronal Damage In Vivo and In Vitro through Inhibition of Oxidative Stress and Proinflammation

(2018) Jung-Min Yon et al.   Nutrients

RNA-Seq transcriptomic profiling of primary murine microglia treated with LPS or LPS + IFNγ

(2018) Marta Pulido-Salgado et al.   Scientific Reports

The Potential of LPS-Binding Protein to Reverse Amyloid Formation in Plasma Fibrin of Individuals With Alzheimer-Type Dementia

(2018) Etheresia Pretorius et al.   Frontiers in Aging Neuroscience

Melatonin Rescue Oxidative Stress-Mediated Neuroinflammation/ Neurodegeneration and Memory Impairment in Scopolamine-Induced Amnesia Mice Model

(2018) Tahir Muhammad et al.   Journal of Neuroimmune Pharmacology

Inhibitory effect of INT-777 on lipopolysaccharide-induced cognitive impairment, neuroinflammation, apoptosis, and synaptic dysfunction in mice

(2018) Xian Wu et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Molecular Targets of Epigallocatechin—Gallate (EGCG): A Special Focus on Signal Transduction and Cancer

(2018) Aide Negri et al.   Nutrients

Effect of Low-Fat Diet in Obese Mice Lacking Toll-like Receptors

(2018) Cheng-Shyuan Rau et al.   Nutrients

Effects of (−)-Epigallocatechin Gallate (EGCG) on Energy Expenditure and Microglia-Mediated Hypothalamic Inflammation in Mice Fed a High-Fat Diet

(2018) Jihong Zhou et al.   Nutrients

Polyphenolic Extract from Tarocco (Citrus sinensis L. Osbeck) Clone “Lempso” Exerts Anti-Inflammatory and Antioxidant Effects via NF-kB and Nrf-2 Activation in Murine Macrophages

(2018) Giacomo Pepe et al.   Nutrients

Lisosan G Protects the Retina from Neurovascular Damage in Experimental Diabetic Retinopathy

(2018) Rosario Amato et al.   Nutrients

Neuroprotective Effect of Quercetin Against the Detrimental Effects of LPS in the Adult Mouse Brain

(2018) Amjad Khan et al.   Frontiers in Pharmacology

Protective Effect of Argan and Olive Oils against LPS-Induced Oxidative Stress and Inflammation in Mice Livers

(2017) Soufiane El Kamouni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Neuroinflammation and Oxidative Stress in Psychosis and Psychosis Risk

(2017) Henry Barron et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Enhanced neuroprotection of anthocyanin-loaded PEG-gold nanoparticles against Aβ 1-42 -induced neuroinflammation and neurodegeneration via the NF- K B /JNK/GSK3β signaling pathway

(2017) Min Ju Kim et al.   Nanomedicine-Nanotechnology Biology and Medicine

Oxidative Stress in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications

(2017) Zewen Liu et al.   Oxidative Medicine and Cellular Longevity

Astrocyte hepcidin is a key factor in LPS-induced neuronal apoptosis

(2017) Lin-Hao You et al.   Cell Death & Disease

The Anti-Inflammatory and Antioxidant Potential of Pistachios (Pistacia vera L.) In Vitro and In Vivo

(2017) Irene Paterniti et al.   Nutrients

Equol, a Dietary Daidzein Gut Metabolite Attenuates Microglial Activation and Potentiates Neuroprotection In Vitro

(2017) Lalita Subedi et al.   Nutrients

12-oxo-phytodienoic acid, a plant-derived oxylipin, attenuates lipopolysaccharide-induced inflammation in microglia

(2016) Nozomi Taki-Nakano et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The protective effect of the natural compound hesperetin against fulminant hepatitisin vivoandin vitro

(2016) Xueting Bai et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role of Nrf2/HO-1 system in development, oxidative stress response and diseases: an evolutionarily conserved mechanism

(2016) Agnieszka Loboda et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

LPS-induced Murine Neuroinflammation Model: Main Features and Suitability for Pre-clinical Assessment of Nutraceuticals

(2016) Miryam Nava Catorce et al.   Current Neuropharmacology

Osmotin attenuates LPS-induced neuroinflammation and memory impairments via the TLR4/NFκB signaling pathway

(2016) Haroon Badshah et al.   Scientific Reports

Idh1 protects murine hepatocytes from endotoxin-induced oxidative stress by regulating the intracellular NADP+/NADPH ratio

(2015) M Itsumi et al.   CELL DEATH AND DIFFERENTIATION

1,25-Dihydroxyvitamin D3 attenuates endotoxin-induced production of inflammatory mediators by inhibiting MAPK activation in primary cortical neuron-glia cultures

(2015) Ya-Ni Huang et al.   Journal of Neuroinflammation

Free radicals, reactive oxygen species, oxidative stress and its classification

(2014) Volodymyr I. Lushchak   CHEMICO-BIOLOGICAL INTERACTIONS

Targeting TNF: a therapeutic strategy for Alzheimer's disease

(2014) Xin Cheng et al.   DRUG DISCOVERY TODAY

Intermittent fasting attenuates lipopolysaccharide-induced neuroinflammation and memory impairment

(2014) Andrea R Vasconcelos et al.   Journal of Neuroinflammation

Neuropharmacological properties and pharmacokinetics of the citrus flavonoids hesperidin and hesperetin — A mini-review

(2014) Ali Roohbakhsh et al.   LIFE SCIENCES

Regulation of Microglia Activity by Glaucocalyxin-A: Attenuation of Lipopolysaccharide-Stimulated Neuroinflammation through NF-κB and p38 MAPK Signaling Pathways

(2013) Byung-Wook Kim et al.   PLoS One

Antioxidant and Anti-Inflammatory Potential of Hesperetin Metabolites Obtained from Hesperetin-Administered Rat Serum: An Ex Vivo Approach

(2011) Hsin-Ling Yang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Obovatol attenuates LPS-induced memory impairments in mice via inhibition of NF-κB signaling pathway

(2011) Dong-Young Choi et al.   NEUROCHEMISTRY INTERNATIONAL

Agmatine prevents LPS-induced spatial memory impairment and hippocampal apoptosis

(2010) Asadollah Zarifkar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Production of Hesperetin Glycosides by Xanthomonas campestris and Cyclodextrin Glucanotransferase and Their Anti-allergic Activities

(2010) Kei Shimoda et al.   Nutrients

Neuroprotective Effects of (−)-Epigallocatechin-3-gallate on Aging Mice Induced by D-Galactose

(2009) Miao He et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Caspase-3 Is Enriched in Postsynaptic Densities and Increased in Alzheimer's Disease

(2008) Natalia Louneva et al.   AMERICAN JOURNAL OF PATHOLOGY

Neuroprotective effects of chronic hesperetin administration in mice

(2008) Eun Jeong Choi et al.   ARCHIVES OF PHARMACAL RESEARCH

The neuroprotective potential of flavonoids: a multiplicity of effects

(2008) David Vauzour et al.   Genes and Nutrition

Neuroprotective effects of hesperetin in mouse primary neurones are independent of CREB activation

(2008) Stephanie Rainey-Smith et al.   NEUROSCIENCE LETTERS