Red Orange: Experimental Models and Epidemiological Evidence of Its Benefits on Human Health

Effects of red orange juice intake on endothelial function and inflammatory markers in adult subjects with increased cardiovascular risk

(2012) Silvio Buscemi et al.   AMERICAN JOURNAL OF CLINICAL NUTRITION

Protocatechuic Acid and Human Disease Prevention: Biological Activities and Molecular Mechanisms

(2012) R. Masella et al.   CURRENT MEDICINAL CHEMISTRY

Ferulic acid, a dietary phenolic acid, modulates radiation effects in Swiss albino mice

(2012) Janakiraman Shanthakumar et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Caffeic Acid Phenylethyl Amide Protects against the Metabolic Consequences in Diabetes Mellitus Induced by Diet and Streptozocin

(2012) Yi-Chun Weng et al.   Evidence-based Complementary and Alternative Medicine

Not Only Melatonin but also Caffeic Acid Phenethyl Ester Protects Kidneys against Aging-related Oxidative Damage in Sprague Dawley Rats

(2012) Mukaddes Eşrefoğlu et al.   ULTRASTRUCTURAL PATHOLOGY

Moroorange juice prevents fatty liver in mice

(2012) Federico Salamone   WORLD JOURNAL OF GASTROENTEROLOGY

Cyanidin-3-O- -Glucoside and Protocatechuic Acid Exert Insulin-Like Effects by Upregulating PPAR  Activity in Human Omental Adipocytes

(2011) B. Scazzocchio et al.   DIABETES

The citrus flavonoid hesperidin induces p53 and inhibits NF-κB activation in order to trigger apoptosis in NALM-6 cells: involvement of PPARγ-dependent mechanism

(2011) Asghar Ghorbani et al.   EUROPEAN JOURNAL OF NUTRITION

Role of hesperetin (a natural flavonoid) and its analogue on apoptosis in HT-29 human colon adenocarcinoma cell line – A comparative study

(2011) Gunasekaran Sivagami et al.   FOOD AND CHEMICAL TOXICOLOGY

Vitamins C and E: Beneficial effects from a mechanistic perspective

(2011) Maret G. Traber et al.   FREE RADICAL BIOLOGY AND MEDICINE

Citrus Polyphenol Hesperidin Stimulates Production of Nitric Oxide in Endothelial Cells while Improving Endothelial Function and Reducing Inflammatory Markers in Patients with Metabolic Syndrome

(2011) Stefano Rizza et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

Modulatory effect of hesperidin on benzo(a)pyrene induced experimental lung carcinogenesis with reference to COX-2, MMP-2 and MMP-9

(2010) Sattu Kamaraj et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Chemopreventive potential of ferulic acid in 7,12-dimethylbenz[a]anthracene-induced mammary carcinogenesis in Sprague–Dawley rats

(2010) Nagarethinam Baskaran et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Efficacy of hesperidin on plasma, heart and liver tissue lipids in rats subjected to isoproterenol-induced cardiotoxicity

(2010) Palanisamy Selvaraj et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Apigenin and naringenin suppress colon carcinogenesis through the aberrant crypt stage in azoxymethane-treated rats

(2010) Tety Leonardi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The effects of caffeic acid phenethyl ester and melatonin on age-related vascular remodeling and cardiac damage

(2010) Mukaddes Eşrefoğlu et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

A comparison of skin delivery of ferulic acid and its derivatives: Evaluation of their efficacy and safety

(2010) Li-Wen Zhang et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Chemical composition of blood orange varieties from Turkey: A comparative study

(2010) Ebru Kafkas et al.   Pharmacognosy Magazine

Hesperidin, a flavanone glycoside, on lipid peroxidation and antioxidant status in experimental myocardial ischemic rats

(2010) Palanisamy Selvaraj et al.   REDOX REPORT

Anthocyanins-based drugs for colon cancer treatment: the nutritionist’s point of view

(2009) Fabio Galvano et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Blood orange juice inhibits fat accumulation in mice

(2009) L Titta et al.   INTERNATIONAL JOURNAL OF OBESITY

Caffeic acid phenethyl ester (CAPE) exhibits significant potential as an antidiabetic and liver-protective agent in streptozotocin-induced diabetic rats

(2009) Sefa Celik et al.   PHARMACOLOGICAL RESEARCH

Caffeic acid phenethyl ester protects mice from lethal endotoxin shock and inhibits lipopolysaccharide-induced cyclooxygenase-2 and inducible nitric oxide synthase expression in RAW 264.7 macrophages via the p38/ERK and NF-κB pathways

(2008) Won-Kyo Jung et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Antioxidant and anticancer efficacy of hesperidin in benzo(a)pyrene induced lung carcinogenesis in mice

(2008) Sattu Kamaraj et al.   INVESTIGATIONAL NEW DRUGS

Changes in Carotenoid Content and Biosynthetic Gene Expression in Juice Sacs of Four Orange Varieties (Citrus sinensis) Differing in Flesh Fruit Color

(2008) Anne-Laure Fanciullino et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Update on Uses and Properties of Citrus Flavonoids: New Findings in Anticancer, Cardiovascular, and Anti-inflammatory Activity

(2008) O. Benavente-García et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ferulic Acid Inhibits 7,12-Dimethylbenz[α]anthracene-Induced Hamster Buccal Pouch Carcinogenesis

(2008) Subramanian Balakrishnan et al.   JOURNAL OF MEDICINAL FOOD

Caffeic acid phenethyl ester (CAPE) protects brain against oxidative stress and inflammation induced by diabetes in rats

(2008) Sefa Celik et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Protocatechuic acid: The missing human cyanidins' metabolite

(2008) Fabio Galvano et al.   MOLECULAR NUTRITION & FOOD RESEARCH

A Novel Prodrug of 4′-Geranyloxy-Ferulic Acid Suppresses Colitis-Related Colon Carcinogenesis in Mice

(2008) Shingo Miyamoto et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Hesperidin inhibited acetaldehyde-induced matrix metalloproteinase-9 gene expression in human hepatocellular carcinoma cells

(2008) Ming-Hsien Yeh et al.   TOXICOLOGY LETTERS

Protective effects of a topical antioxidant mixture containing vitamin C, ferulic acid, and phloretin against ultraviolet-induced photodamage in human skin

(2008) Christian Oresajo et al.   Journal of Cosmetic Dermatology

Apoptotic effect of hesperidin through caspase3 activation in human colon cancer cells, SNU-C4

(2007) H.J. Park et al.   PHYTOMEDICINE