- Home
- Publications
- Publication Search
- Publication Details
Title
A Guide to Targeting the Endocannabinoid System in Drug Design
Authors
Keywords
-
Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 21, Issue 8, Pages 2778
Publisher
MDPI AG
Online
2020-04-17
DOI
10.3390/ijms21082778
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- The endocannabinoid hydrolase FAAH is an allosteric enzyme
- (2020) Enrico Dainese et al. Scientific Reports
- Effect of TRPV1 Antagonist SC0030, a Potent Painkiller, on RANKL‐mediated Osteoclast Differentiation Involved in Bone Resorption
- (2020) Kunal N. More et al. BULLETIN OF THE KOREAN CHEMICAL SOCIETY
- Cannabis, cannabinoid receptors, and endocannabinoid system: yesterday, today, and tomorrow
- (2019) Jie Wu ACTA PHARMACOLOGICA SINICA
- Crystal Structure of the Human Cannabinoid Receptor CB2
- (2019) Xiaoting Li et al. CELL
- Multiple endocannabinoid-mediated mechanisms in the regulation of energy homeostasis in brain and peripheral tissues
- (2019) Inigo Ruiz de Azua et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Negative Allosteric Modulators of Cannabinoid Receptor 2: Protein Modeling, Binding Site Identification and Molecular Dynamics Simulations in the Presence of an Orthosteric Agonist
- (2019) Pankaj Pandey et al. JOURNAL OF BIOMOLECULAR STRUCTURE & DYNAMICS
- MicroRNA-29a Attenuates Diabetic Glomerular Injury through Modulating Cannabinoid Receptor 1 Signaling
- (2019) Chun-Wu Tung et al. MOLECULES
- Hypothalamic endocannabinoid signalling modulates aversive responses related to panic attacks
- (2019) Thércia G. Viana et al. NEUROPHARMACOLOGY
- Cannabinoid Receptor Type 1 Agonist ACEA Improves Cognitive Deficit on STZ-Induced Neurotoxicity Through Apoptosis Pathway and NO Modulation
- (2019) Fernanda Crunfli et al. NEUROTOXICITY RESEARCH
- Deficiency of Monoacylglycerol Lipase Enhances IgM Plasma Levels and Limits Atherogenesis in a CB2-Dependent Manner
- (2019) Raquel Guillamat Prats et al. THROMBOSIS AND HAEMOSTASIS
- The role of the endocannabinoid system in female reproductive tissues
- (2019) O’Llenecia S. Walker et al. Journal of Ovarian Research
- Decreased Expression of Cannabinoid Receptors in the Eutopic and Ectopic Endometrium of Patients with Adenomyosis
- (2019) Xue Shen et al. Biomed Research International
- Cannabinoid Ligands Targeting TRP Channels
- (2019) Chanté Muller et al. Frontiers in Molecular Neuroscience
- Contribution of Altered Endocannabinoid System to Overactive mTORC1 Signaling in Focal Cortical Dysplasia
- (2019) Daniel García-Rincón et al. Frontiers in Pharmacology
- Anti-inflammatory mechanisms of cannabinoids: an immunometabolic perspective
- (2019) G. van Niekerk et al. INFLAMMOPHARMACOLOGY
- Atypical cannabinoid ligands O-1602 and O-1918 administered chronically in diet-induced obesity
- (2019) Anna C Simcocks et al. Endocrine Connections
- Members of the endocannabinoid system are distinctly regulated in inflammatory bowel disease and colorectal cancer
- (2019) Magdalena Grill et al. Scientific Reports
- Endocannabinoid Signalling in Atherosclerosis and Related Metabolic Complications
- (2019) Raquel Guillamat-Prats et al. THROMBOSIS AND HAEMOSTASIS
- Cardiovascular effects of cannabis (marijuana): A timely update
- (2019) Angel E. Sánchez Artiles et al. PHYTOTHERAPY RESEARCH
- Cannabinoid Signaling in the Skin: Therapeutic Potential of the “C(ut)annabinoid” System
- (2019) Kinga Tóth et al. MOLECULES
- Targeting CB1 and GPR55 Endocannabinoid Receptors as a Potential Neuroprotective Approach for Parkinson’s Disease
- (2019) Eva Martínez-Pinilla et al. MOLECULAR NEUROBIOLOGY
- Optimization of a Benzoylpiperidine Class Identifies a Highly Potent and Selective Reversible Monoacylglycerol Lipase (MAGL) Inhibitor
- (2019) Carlotta Granchi et al. JOURNAL OF MEDICINAL CHEMISTRY
- TLR4 Receptor Induces 2-AG–Dependent Tolerance to Lipopolysaccharide and Trafficking of CB2 Receptor in Mast Cells
- (2019) Zyanya P. Espinosa-Riquer et al. JOURNAL OF IMMUNOLOGY
- Positive and Negative Effects of Cannabis and Cannabinoids on Health
- (2019) Koby Cohen et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The effect of cannabinoid receptor 1 blockade on adipokine and proinflammatory cytokine concentration in adipose and hepatic tissue in mice with nonalcoholic fatty liver disease
- (2019) Bojan Jorgačević et al. CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY
- Novel protective effect of O-1602 and abnormal cannabidiol, GPR55 agonists, on ER stress-induced apoptosis in pancreatic β-cells
- (2019) Chi Teng Vong et al. BIOMEDICINE & PHARMACOTHERAPY
- Cannabinoid derivatives acting as dual PPARγ/CB2 agonists as therapeutic agents for systemic sclerosis
- (2019) Adela García-Martín et al. BIOCHEMICAL PHARMACOLOGY
- Ketamine-induced antidepressant like effects in mice: A possible involvement of cannabinoid system
- (2019) Fatemeh Khakpai et al. BIOMEDICINE & PHARMACOTHERAPY
- Targeting Peripheral CB1 Receptors Reduces Ethanol Intake via a Gut-Brain Axis
- (2019) Grzegorz Godlewski et al. Cell Metabolism
- 5-Chlorobenzofuran-2-carboxamides: From allosteric CB1 modulators to potential apoptotic antitumor agents
- (2019) Bahaa G.M. Youssif et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- The Endocannabinoid/Endovanilloid System in Bone: From Osteoporosis to Osteosarcoma
- (2019) Rossi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Structural Insights into CB1 Receptor Biased Signaling
- (2019) Al-Zoubi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Endocannabinoid System in Hepatic Glucose Metabolism, Fatty Liver Disease, and Cirrhosis
- (2019) Ivonne Bazwinsky-Wutschke et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Cannabinoid type-1 receptor blockade restores neurological phenotypes in two models for Down syndrome
- (2019) Alba Navarro-Romero et al. NEUROBIOLOGY OF DISEASE
- Synergistic action of CB1 and 5-HT2B receptors in preventing pilocarpine-induced status epilepticus in rats
- (2019) Roberto Colangeli et al. NEUROBIOLOGY OF DISEASE
- Forsythiaside prevents β-amyloid-induced hippocampal slice injury by upregulating 2-arachidonoylglycerol via cannabinoid receptor 1-dependent NF-κB pathway
- (2019) Liqing Chen et al. NEUROCHEMISTRY INTERNATIONAL
- Ketamine induces central antinociception mediated by endogenous cannabinoids and activation of CB1 receptors
- (2019) Daniela da Fonseca Pacheco et al. NEUROSCIENCE LETTERS
- Endocannabinoid system and the expression of endogenous ceramides in human hepatocellular carcinoma
- (2019) Jiayong Yang et al. Oncology Letters
- Endocannabinoid System in Spinocerebellar Ataxia Type-3 and Other Autosomal-Dominant Cerebellar Ataxias: Potential Role in Pathogenesis and Expected Relevance as Neuroprotective Targets
- (2019) María Gómez-Ruiz et al. Frontiers in Molecular Neuroscience
- The Endocannabinoid System as a Target in Cancer Diseases: Are We There Yet?
- (2019) Estefanía Moreno et al. Frontiers in Pharmacology
- Modulation of the Endocannabinoid System as a Potential Anticancer Strategy
- (2019) Robert Ramer et al. Frontiers in Pharmacology
- Paradoxical effects of JZL184, an inhibitor of monoacylglycerol lipase, on bone remodelling in healthy and cancer-bearing mice
- (2019) Silvia Marino et al. EBioMedicine
- Anti-Inflammatory Effects by Pharmacological Inhibition or Knockdown of Fatty Acid Amide Hydrolase in BV2 Microglial Cells
- (2019) Mikiei Tanaka et al. Cells
- The role of 2-arachidonoylglycerol in the regulation of the tumor-immune microenvironment in murine models of pancreatic cancer
- (2019) Chongyang Qiu et al. BIOMEDICINE & PHARMACOTHERAPY
- Nabilone administration in refractory chronic diarrhea: a case series
- (2019) Lanfranco Pellesi et al. BMC GASTROENTEROLOGY
- The novel cannabinoid 1 receptor agonist AM11101 increases food intake in female rats.
- (2019) Sean B. Ogden et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabinoid receptors as therapeutic targets for autoimmune diseases: where do we stand?
- (2019) Elaine D. Gonçalves et al. DRUG DISCOVERY TODAY
- Anandamide-nanoformulation obtained by electrospraying for cardiovascular therapy
- (2019) Virna Margarita Martín Giménez et al. INTERNATIONAL JOURNAL OF PHARMACEUTICS
- Effect of monoacylglycerol lipase on the tumor growth in endometrial cancer
- (2019) Xin Li et al. JOURNAL OF OBSTETRICS AND GYNAECOLOGY RESEARCH
- Positive allosteric modulation of the type 1 cannabinoid receptor reduces the signs and symptoms of Huntington's disease in the R6/2 mouse model
- (2019) Robert B. Laprairie et al. NEUROPHARMACOLOGY
- Endocannabinoid and Prostanoid Crosstalk in Pain
- (2019) Baptiste Buisseret et al. TRENDS IN MOLECULAR MEDICINE
- Targeting GPCRs Activated by Fatty Acid-Derived Lipids in Type 2 Diabetes
- (2019) Edyta Gendaszewska-Darmach et al. TRENDS IN MOLECULAR MEDICINE
- CB2 receptor deletion on myeloid cells enhanced mechanical allodynia in a mouse model of neuropathic pain
- (2019) Elisa Nent et al. Scientific Reports
- Acute Administration of URB597 Fatty Acid Amide Hydrolase Inhibitor Prevents Attentional Impairments by Distractors in Adolescent Mice
- (2019) Gabriella Contarini et al. Frontiers in Pharmacology
- Antitumor Cannabinoid Chemotypes: Structural Insights
- (2019) Paula Morales et al. Frontiers in Pharmacology
- Elevated Anandamide, Enhanced Recall of Fear Extinction, and Attenuated Stress Responses Following Inhibition of Fatty Acid Amide Hydrolase: A Randomized, Controlled Experimental Medicine Trial
- (2019) Leah M. Mayo et al. BIOLOGICAL PSYCHIATRY
- Allosteric modulators targeting cannabinoid cb1 and cb2 receptors: implications for drug discovery
- (2019) Francesca Gado et al. Future Medicinal Chemistry
- New Approaches to Cancer Therapy: Combining Fatty Acid Amide Hydrolase (FAAH) Inhibition with Peroxisome Proliferator-Activated Receptors (PPARs) Activation
- (2019) Leonardo Brunetti et al. JOURNAL OF MEDICINAL CHEMISTRY
- Myocardial maladaptation to pressure overload in CB2 receptor-deficient mice
- (2019) Georg D. Duerr et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Alcohol-induced conditioned place preference is modulated by CB2 cannabinoid receptors and modifies levels of endocannabinoids in the mesocorticolimbic system
- (2019) Ana Martín-Sánchez et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Therapeutic potential of cannabinoid receptor 2 in the treatment of diabetes mellitus and its complications
- (2019) Vivek S. Kumawat et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Structure of an allosteric modulator bound to the CB1 cannabinoid receptor
- (2019) Zhenhua Shao et al. Nature Chemical Biology
- Monoacylglycerol lipase inhibitors: Modulators for lipid metabolism in cancer malignancy, neurological and metabolic disorders
- (2019) Hui Deng et al. Acta Pharmaceutica Sinica B
- A perspective review on fatty acid amide hydrolase (FAAH) inhibitors as potential therapeutic agents
- (2019) Rati Kailash Prasad Tripathi EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Preclinical toxicity evaluation of JD5037, a peripherally restricted CB1 receptor inverse agonist, in rats and dogs for treatment of nonalcoholic steatohepatitis
- (2019) Vijay Pralhad Kale et al. REGULATORY TOXICOLOGY AND PHARMACOLOGY
- Cannabinoid signalling in embryonic and adult neurogenesis: possible implications for psychiatric and neurological disorders
- (2018) Rúbia W. de Oliveira et al. ACTA NEUROPSYCHIATRICA
- Cannabinoid CB1 receptor neutral antagonist AM4113 inhibits heroin self-administration without depressive side effects in rats
- (2018) Xiang-hu He et al. ACTA PHARMACOLOGICA SINICA
- Endocannabinoids in Islets of Langerhans: The Ugly, the Bad and the Good Facts
- (2018) Isabel González-Mariscal et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- FAAH inhibition attenuates TLR3-mediated hyperthermia, nociceptive- and anxiety-like behaviour in female rats
- (2018) Lisa E. Flannery et al. BEHAVIOURAL BRAIN RESEARCH
- From pathogenesis to clinical practice: Emerging medical treatments for endometriosis
- (2018) Sara Clemenza et al. BEST PRACTICE & RESEARCH CLINICAL OBSTETRICS & GYNAECOLOGY
- Molecular and functional interaction between GPR18 and cannabinoid CB 2 G-protein-coupled receptors. Relevance in neurodegenerative diseases
- (2018) Irene Reyes-Resina et al. BIOCHEMICAL PHARMACOLOGY
- The Lateral Habenula Directs Coping Styles Under Conditions of Stress Via Recruitment of the Endocannabinoid System
- (2018) Anthony L. Berger et al. BIOLOGICAL PSYCHIATRY
- JZL184, as a monoacylglycerol lipase inhibitor, down-regulates inflammation in a cannabinoid pathway dependent manner
- (2018) Mohammad-Reza Rahmani et al. BIOMEDICINE & PHARMACOTHERAPY
- Involvement of the CB2 cannabinoid receptor in cell growth inhibition and G0/G1 cell cycle arrest via the cannabinoid agonist WIN 55,212–2 in renal cell carcinoma
- (2018) Mohammed I. Khan et al. BMC CANCER
- Effect of endocannabinoid signalling on cell fate: life, death, differentiation and proliferation of brain cells
- (2018) Moises Garcia-Arencibia et al. BRITISH JOURNAL OF PHARMACOLOGY
- Species-specific susceptibility to cannabis-induced convulsions
- (2018) Benjamin J Whalley et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabinoids in arterial, pulmonary and portal hypertension - mechanisms of action and potential therapeutic significance
- (2018) Barbara Malinowska et al. BRITISH JOURNAL OF PHARMACOLOGY
- Activation of GPR55 increases neural stem cell proliferation and promotes early adult hippocampal neurogenesis
- (2018) Jeremy D Hill et al. BRITISH JOURNAL OF PHARMACOLOGY
- Anti-tumoural actions of cannabinoids
- (2018) Burkhard Hinz et al. BRITISH JOURNAL OF PHARMACOLOGY
- Potent Anti-Inflammatory and Pro-Resolving Effects of Anabasum in a Human Model of Self-Resolving Acute Inflammation
- (2018) Madhur P. Motwani et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- Fatty Acid Amide Hydrolase Inhibition by JNJ-42165279: A Multiple-Ascending Dose and a Positron Emission Tomography Study in Healthy Volunteers
- (2018) Andrey Postnov et al. CTS-Clinical and Translational Science
- The Case for Cannabinoid CB1 Receptors as a Target for Bronchodilator Therapy for β-agonist Resistant Asthma
- (2018) John C. Ashton et al. CURRENT DRUG TARGETS
- Peripheral cannabinoid 1 receptor blockade mitigates adipose tissue inflammation via NLRP3 inflammasome in mouse models of obesity
- (2018) Ji H. Han et al. DIABETES OBESITY & METABOLISM
- TRPV1 mediates the anticonvulsant effects of acetaminophen in mice
- (2018) Katsuya Suemaru et al. EPILEPSY RESEARCH
- Anticonvulsant effects of acetaminophen in mice: Comparison with the effects of nonsteroidal anti-inflammatory drugs
- (2018) Katsuya Suemaru et al. EPILEPSY RESEARCH
- Polypharmacological profile of 1,2-dihydro-2-oxo-pyridine-3-carboxamides in the endocannabinoid system
- (2018) Andrea Chicca et al. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
- Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
- (2018) et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Anti-Proliferative Properties and Proapoptotic Function of New CB2 Selective Cannabinoid Receptor Agonist in Jurkat Leukemia Cells
- (2018) Antonella Capozzi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Inhibition of Fatty Acid Amide Hydrolase by PF-3845 Alleviates the Nitrergic and Proinflammatory Response in Rat Hippocampus Following Acute Stress
- (2018) Hsiao-Jou Cortina Chen et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Endocannabinoid Tone Regulates Human Sebocyte Biology
- (2018) Nóra Zákány et al. JOURNAL OF INVESTIGATIVE DERMATOLOGY
- Identification of the first synthetic allosteric modulator of the CB2 receptors and evidence of its efficacy for neuropathic pain relief
- (2018) Francesca Gado et al. JOURNAL OF MEDICINAL CHEMISTRY
- Cannabinoid-induced cell death in endometrial cancer cells: involvement of TRPV1 receptors in apoptosis
- (2018) B. M. Fonseca et al. JOURNAL OF PHYSIOLOGY AND BIOCHEMISTRY
- Activation of the capsaicin-receptor TRPV1 by the acetaminophen metabolite N -arachidonoylaminophenol results in cytotoxicity
- (2018) Thomas Stueber et al. LIFE SCIENCES
- Anticonvulsive effects of endocannabinoids; an investigation to determine the role of regulatory components of endocannabinoid metabolism in the Pentylenetetrazol induced tonic- clonic seizures
- (2018) Parisa Zareie et al. METABOLIC BRAIN DISEASE
- The Pharmacological Inhibition of Fatty Acid Amide Hydrolase Prevents Excitotoxic Damage in the Rat Striatum: Possible Involvement of CB1 Receptors Regulation
- (2018) Gabriela Aguilera-Portillo et al. MOLECULAR NEUROBIOLOGY
- Cannabinoid-1 receptor neutral antagonist reduces binge-like alcohol consumption and alcohol-induced accumbal dopaminergic signaling
- (2018) Andrea Balla et al. NEUROPHARMACOLOGY
- Pharmacological inhibition of 2-arachidonoilglycerol hydrolysis enhances memory consolidation in rats through CB2 receptor activation and mTOR signaling modulation
- (2018) Patrizia Ratano et al. NEUROPHARMACOLOGY
- Synthetic peripherally-restricted cannabinoid suppresses chemotherapy-induced peripheral neuropathy pain symptoms by CB1 receptor activation
- (2018) Yatendra Mulpuri et al. NEUROPHARMACOLOGY
- Inhibition of endocannabinoid degradation rectifies motivational and dopaminergic deficits in the Q175 mouse model of Huntington’s disease
- (2018) Dan P. Covey et al. NEUROPSYCHOPHARMACOLOGY
- Cannabis and cannabinoids for the treatment of people with chronic non-cancer pain conditions
- (2018) Emily Stockings et al. PAIN
- Medial prefrontal cortex TRPV1 and CB1 receptors modulate cardiac baroreflex activity by regulating the NMDA receptor/nitric oxide pathway
- (2018) Davi C. Lagatta et al. PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Cannabinoids prevent depressive-like symptoms and alterations in BDNF expression in a rat model of PTSD
- (2018) Or Burstein et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Pharmacological augmentation of endocannabinoid signaling reduces the neuroendocrine response to stress
- (2018) Pablo Nicolás Surkin et al. PSYCHONEUROENDOCRINOLOGY
- The Emerging Role of TRPV1 in Airway Inflammation
- (2018) Joo-Hee Kim Allergy Asthma & Immunology Research
- Cannabinoid signalling in embryonic and adult neurogenesis: possible implications for psychiatric and neurological disorders
- (2018) Rúbia W. de Oliveira et al. ACTA NEUROPSYCHIATRICA
- The Grass Might Be Greener: Medical Marijuana Patients Exhibit Altered Brain Activity and Improved Executive Function after 3 Months of Treatment
- (2018) Staci A. Gruber et al. Frontiers in Pharmacology
- Dronabinol oral solution in the management of anorexia and weight loss in AIDS and cancer
- (2018) Melissa Badowski et al. Therapeutics and Clinical Risk Management
- Bioactive Lipids and Chronic Inflammation: Managing the Fire Within
- (2018) Valerio Chiurchiù et al. Frontiers in Immunology
- Redox system and phospholipid metabolism in the kidney of hypertensive rats after FAAH inhibitor URB597 administration
- (2018) Michał Biernacki et al. Redox Biology
- Role of Endocannabinoid System in the Peripheral Antinociceptive Action of Aripiprazole
- (2018) Renata C. M. Ferreira et al. ANESTHESIA AND ANALGESIA
- The endocannabinoid 2-arachidonoylglycerol regulates oligodendrocyte progenitor cell migration
- (2018) Maria A. Sanchez-Rodriguez et al. BIOCHEMICAL PHARMACOLOGY
- Monoacylglycerol lipase (MAGL) as a promising therapeutic target
- (2018) Ana Gil-Ordóñez et al. BIOCHEMICAL PHARMACOLOGY
- Genetic deletion of CB1 cannabinoid receptors exacerbates the Alzheimer-like symptoms in a transgenic animal model
- (2018) Ester Aso et al. BIOCHEMICAL PHARMACOLOGY
- Pharmacological regulation of cannabinoid CB2 receptor modulates the reinforcing and motivational actions of ethanol
- (2018) Francisco Navarrete et al. BIOCHEMICAL PHARMACOLOGY
- Pharmacological blockade of fatty acid amide hydrolase (FAAH) by URB597 improves memory and changes the phenotype of hippocampal microglia despite ethanol exposure
- (2018) Patricia Rivera et al. BIOCHEMICAL PHARMACOLOGY
- Opposing roles of CB1 and CB2 cannabinoid receptors in the stimulant and rewarding effects of cocaine
- (2018) Pedro H Gobira et al. BRITISH JOURNAL OF PHARMACOLOGY
- REVERSAL OF ALBUMINURIA BY COMBINED AM6545 AND PERINDOPRIL THERAPY IN EXPERIMENTAL DIABETIC NEPHROPATHY
- (2018) F Barutta et al. BRITISH JOURNAL OF PHARMACOLOGY
- VCE-004.3, a cannabidiol aminoquinone derivative, prevents bleomycin-induced skin fibrosis and inflammation through PPARγ- and CB2 receptor-dependent pathways
- (2018) Carmen del Rio et al. BRITISH JOURNAL OF PHARMACOLOGY
- OUP accepted manuscript
- (2018) CEREBRAL CORTEX
- Development of Potent Inhibitors of Fatty Acid Amide Hydrolase Useful for the Treatment of Neuropathic Pain
- (2018) Margherita Brindisi et al. ChemMedChem
- The novel peripherally active cannabinoid type 1 and serotonin type 3 receptor agonist AM9405 inhibits gastrointestinal motility and reduces abdominal pain in mouse models mimicking irritable bowel syndrome
- (2018) Maciej Salaga et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues
- (2018) Christopher Lipina et al. FASEB JOURNAL
- Anandamide inhibits FcεRI-dependent degranulation and cytokine synthesis in mast cells through CB2 and GPR55 receptor activation. Possible involvement of CB2-GPR55 heteromers
- (2018) Silvia L. Cruz et al. INTERNATIONAL IMMUNOPHARMACOLOGY
- Role of Cannabinoids in Obesity
- (2018) Francesca Rossi et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Targeted inhibition of the type 2 cannabinoid receptor is a novel approach to reduce renal fibrosis
- (2018) Lili Zhou et al. KIDNEY INTERNATIONAL
- New approaches and challenges to targeting the endocannabinoid system
- (2018) Vincenzo Di Marzo NATURE REVIEWS DRUG DISCOVERY
- Neuroprotective effects of fatty acid amide hydrolase catabolic enzyme inhibition in a HIV-1 Tat model of neuroAIDS
- (2018) Douglas J. Hermes et al. NEUROPHARMACOLOGY
- Combined CB2 Receptor Agonist and Photodynamic Therapy Synergistically Inhibit Tumor Growth in Triple Negative Breast Cancer
- (2018) Jiliang Zhang et al. Photodiagnosis and Photodynamic Therapy
- Cannabinoid 1 receptor signaling on GABAergic neurons influences astrocytes in the ageing brain
- (2018) Andras Bilkei-Gorzo et al. PLoS One
- CB1 receptor blockade ameliorates hepatic fat infiltration and inflammation and increases Nrf2-AMPK pathway in a rat model of severely uncontrolled diabetes
- (2018) Eugene Chang et al. PLoS One
- Inflammation and CB2 signaling drive novel changes in the ocular lipidome and regulate immune cell activity in the eye
- (2018) JT Toguri et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- Effects of fatty acid amide hydrolase inhibitor URB597 in a rat model of trauma-induced long-term anxiety
- (2018) Andalib Danandeh et al. PSYCHOPHARMACOLOGY
- The exogenous administration of CB2 specific agonist, GW405833, inhibits inflammation by reducing cytokine production and oxidative stress
- (2018) Ali Parlar et al. Experimental and Therapeutic Medicine
- Genetic and pharmacological regulation of the endocannabinoid CB1 receptor in Duchenne muscular dystrophy
- (2018) Fabio A. Iannotti et al. Nature Communications
- Cannabinoid 1 Receptor Signaling on Hippocampal GABAergic Neurons Influences Microglial Activity
- (2018) Frank Ativie et al. Frontiers in Molecular Neuroscience
- Cannabinoids: Potential Role in Inflammatory and Neoplastic Skin Diseases
- (2018) Rose Milando et al. AMERICAN JOURNAL OF CLINICAL DERMATOLOGY
- Structural properties and role of the endocannabinoid lipases ABHD6 and ABHD12 in lipid signalling and disease
- (2018) Laura Kind et al. AMINO ACIDS
- Palmitoylethanolamide Promotes a Proresolving Macrophage Phenotype and Attenuates Atherosclerotic Plaque Formation
- (2018) Petteri Rinne et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Monoacylglycerol Lipase Inactivation by Using URB602 Mitigates Myocardial Damage in a Rat Model of Cardiac Arrest
- (2018) Kerong Hai et al. CRITICAL CARE MEDICINE
- Medical Use of Cannabinoids
- (2018) Ana Isabel Fraguas-Sánchez et al. DRUGS
- Impact of FAAH genetic variation on fronto-amygdala function during emotional processing
- (2018) Anne Gärtner et al. EUROPEAN ARCHIVES OF PSYCHIATRY AND CLINICAL NEUROSCIENCE
- Cannabidiol reduces airway inflammation and fibrosis in experimental allergic asthma
- (2018) Francieli Vuolo et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- A novel peripheral cannabinoid 1 receptor antagonist, AJ5012, improves metabolic outcomes and suppresses adipose tissue inflammation in obese mice
- (2018) Ji Hye Han et al. FASEB JOURNAL
- Central adiponectin induces trabecular bone mass partly through epigenetic downregulation of cannabinoid receptor CB1
- (2018) Hua Jiang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Cannabis, Cannabinoids, and the Endocannabinoid System—Is there Therapeutic Potential for Inflammatory Bowel Disease?
- (2018) Tim Ambrose et al. Journal of Crohns & Colitis
- Anti-neuroinflammatory effects of GPR55 antagonists in LPS-activated primary microglial cells
- (2018) Soraya Wilke Saliba et al. Journal of Neuroinflammation
- Upregulation of Anandamide Hydrolysis in the Basolateral Complex of Amygdala Reduces Fear Memory Expression and Indices of Stress and Anxiety
- (2018) Maria Morena et al. JOURNAL OF NEUROSCIENCE
- Monoacylglycerol Lipase Inhibition in Human and Rodent Systems Supports Clinical Evaluation of Endocannabinoid Modulators
- (2018) Jason R. Clapper et al. JOURNAL OF PHARMACOLOGY AND EXPERIMENTAL THERAPEUTICS
- Cannabinoids in depressive disorders
- (2018) Ewa Poleszak et al. LIFE SCIENCES
- Impaired anandamide/palmitoylethanolamide signaling in hippocampal glutamatergic neurons alters synaptic plasticity, learning, and emotional responses
- (2018) Tina Zimmermann et al. NEUROPSYCHOPHARMACOLOGY
- Endocannabinoid control of the insular-bed nucleus of the stria terminalis circuit regulates negative affective behavior associated with alcohol abstinence
- (2018) Samuel W. Centanni et al. NEUROPSYCHOPHARMACOLOGY
- An Analysis of Endocannabinoid Concentrations and Mood Following Singing and Exercise in Healthy Volunteers
- (2018) Nicole L. Stone et al. Frontiers in Behavioral Neuroscience
- TrpV1 receptor activation rescues neuronal function and network gamma oscillations from Aβ-induced impairment in mouse hippocampus in vitro
- (2018) Hugo Balleza-Tapia et al. eLife
- Activating Cannabinoid Receptor 2 Protects Against Diabetic Cardiomyopathy Through Autophagy Induction
- (2018) Aiping Wu et al. Frontiers in Pharmacology
- Therapeutic Effect of the Substrate-Selective COX-2 Inhibitor IMMA in the Animal Model of Chronic Constriction Injury
- (2018) Melissa Jones et al. Frontiers in Pharmacology
- Pathophysiological Alterations of Redox Signaling and Endocannabinoid System in Granulocytes and Plasma of Psoriatic Patients
- (2018) Ewa Ambrożewicz et al. Cells
- Cannabinoid receptor type-1 partially mediates metabolic endotoxemia-induced inflammation and insulin resistance
- (2018) Zachary I. Grunewald et al. PHYSIOLOGY & BEHAVIOR
- CB1 positive allosteric modulation attenuates Δ9-THC withdrawal and NSAID-induced gastric inflammation
- (2018) K.R. Trexler et al. PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR
- Inhibition of CB1 receptor ameliorates spatial learning and memory impairment in mice with traumatic brain injury
- (2018) Xiaoming Xu et al. NEUROSCIENCE LETTERS
- Cannabis and epilepsy: An ancient treatment returns to the fore
- (2017) Ethan B. Russo EPILEPSY & BEHAVIOR
- Pharmacology of cannabinoids in the treatment of epilepsy
- (2017) Tyler E. Gaston et al. EPILEPSY & BEHAVIOR
- APD668, a G protein-coupled receptor 119 agonist improves fat tolerance and attenuates fatty liver in high-trans fat diet induced steatohepatitis model in C57BL/6 mice
- (2017) Umakant Ashok Bahirat et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- G protein-coupled receptor GPR55 promotes colorectal cancer and has opposing effects to cannabinoid receptor 1
- (2017) Carina Hasenoehrl et al. INTERNATIONAL JOURNAL OF CANCER
- Endocannabinoid-related compounds in gastrointestinal diseases
- (2017) Marcella Pesce et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Activation of cannabinoid receptor type 2 attenuates surgery-induced cognitive impairment in mice through anti-inflammatory activity
- (2017) Lingling Sun et al. Journal of Neuroinflammation
- Safety, Pharmacokinetics, and Pharmacodynamics Study in Healthy Subjects of Oral NEO6860, a Modality Selective Transient Receptor Potential Vanilloid Subtype 1 Antagonist
- (2017) William Brown et al. JOURNAL OF PAIN
- Modulation of Renal GLUT2 by the Cannabinoid-1 Receptor: Implications for the Treatment of Diabetic Nephropathy
- (2017) Liad Hinden et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Expression of monoacylglycerol lipase as a marker of tumour invasion and progression in malignant melanoma
- (2017) Yuko Baba et al. JOURNAL OF THE EUROPEAN ACADEMY OF DERMATOLOGY AND VENEREOLOGY
- A chronic low dose of Δ9-tetrahydrocannabinol (THC) restores cognitive function in old mice
- (2017) Andras Bilkei-Gorzo et al. NATURE MEDICINE
- Efecto del inhibidor de amida hidrolasa de ácidos grasos en el daño neuronal dopaminérgico inducido por MPTP
- (2017) J.M. Viveros-Paredes et al. NEUROLOGIA
- Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities
- (2017) Leepakshi Khurana et al. NEUROPHARMACOLOGY
- CB1 Receptor Signaling in the Brain: Extracting Specificity from Ubiquity
- (2017) Arnau Busquets-Garcia et al. NEUROPSYCHOPHARMACOLOGY
- The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain
- (2017) Giulia Donvito et al. NEUROPSYCHOPHARMACOLOGY
- Pharmacological inhibition of MAGL attenuates experimental colon carcinogenesis
- (2017) Ester Pagano et al. PHARMACOLOGICAL RESEARCH
- Characterization of structurally novel G protein biased CB 1 agonists: Implications for drug development
- (2017) Benjamin M. Ford et al. PHARMACOLOGICAL RESEARCH
- Tumor-promoting effects of cannabinoid receptor type 1 in human melanoma cells
- (2017) Sara Carpi et al. TOXICOLOGY IN VITRO
- The dual DPP4 inhibitor and GPR119 agonist HBK001 regulates glycemic control and beta cell function ex and in vivo
- (2017) Yi Huan et al. Scientific Reports
- Understand spiciness: mechanism of TRPV1 channel activation by capsaicin
- (2017) Fan Yang et al. Protein & Cell
- Metabolism of the Endocannabinoid Anandamide: Open Questions after 25 Years
- (2017) Mauro Maccarrone Frontiers in Molecular Neuroscience
- First evidence of the conversion of paracetamol to AM404 in human cerebrospinal fluid
- (2017) Chhaya Sharma et al. Journal of Pain Research
- A novel crosstalk within the endocannabinoid system controls GABA transmission in the striatum
- (2017) A. Musella et al. Scientific Reports
- Cannabinoid type 2 receptors in dopamine neurons inhibits psychomotor behaviors, alters anxiety, depression and alcohol preference
- (2017) Qing-Rong Liu et al. Scientific Reports
- Positive Allosteric Modulation of Cannabinoid Receptor Type 1 Suppresses Pathological Pain Without Producing Tolerance or Dependence
- (2017) Richard A. Slivicki et al. BIOLOGICAL PSYCHIATRY
- Selective Cannabinoid Receptor-1 Agonists Regulate Mast Cell Activation in an Oxazolone-Induced Atopic Dermatitis Model
- (2016) Gaewon Nam et al. Annals of Dermatology
- Allosterism and Structure in Thermally Activated Transient Receptor Potential Channels
- (2016) Ignacio Diaz-Franulic et al. Annual Review of Biophysics
- An update on PPAR activation by cannabinoids
- (2016) Saoirse Elizabeth O'Sullivan BRITISH JOURNAL OF PHARMACOLOGY
- Crystal Structure of the Human Cannabinoid Receptor CB 1
- (2016) Tian Hua et al. CELL
- The CB2 receptor and its role as a regulator of inflammation
- (2016) Caroline Turcotte et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Simultaneous Activation of Induced Heterodimerization between CXCR4 Chemokine Receptor and Cannabinoid Receptor 2 (CB2) Reveals a Mechanism for Regulation of Tumor Progression
- (2016) Christopher J. Coke et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Regulation, Signaling, and Physiological Functions of G-Proteins
- (2016) Viktoriya Syrovatkina et al. JOURNAL OF MOLECULAR BIOLOGY
- Allosteric Modulation: An Alternate Approach Targeting the Cannabinoid CB1 Receptor
- (2016) Thuy Nguyen et al. MEDICINAL RESEARCH REVIEWS
- Monoacylglycerol lipase inhibitor JZL184 regulates apoptosis and migration of colorectal cancer cells
- (2016) MUYUAN MA et al. Molecular Medicine Reports
- Acute Neurologic Disorder from an Inhibitor of Fatty Acid Amide Hydrolase
- (2016) Anne Kerbrat et al. NEW ENGLAND JOURNAL OF MEDICINE
- Age-specific influences of chronic administration of the fatty acid amide hydrolase inhibitor URB597 on cardiovascular parameters and organ hypertrophy in DOCA-salt hypertensive rats
- (2016) Marek Toczek et al. Pharmacological Reports
- From Phytocannabinoids to Cannabinoid Receptors and Endocannabinoids: Pleiotropic Physiological and Pathological Roles Through Complex Pharmacology
- (2016) Alessia Ligresti et al. PHYSIOLOGICAL REVIEWS
- α/β-Hydrolase domain-containing 6 (ABHD6) negatively regulates the surface delivery and synaptic function of AMPA receptors
- (2016) Mengping Wei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The effect of cannabinoids on dinitrofluorobenzene-induced experimental asthma in mice
- (2016) Turgut Emrah Bozkurt et al. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
- Treatment with the GPR55 antagonist CID16020046 increases neutrophil activation in mouse atherogenesis
- (2016) Alexander I. Bondarenko et al. THROMBOSIS AND HAEMOSTASIS
- Beyond Cannabis: Plants and the Endocannabinoid System
- (2016) Ethan B. Russo TRENDS IN PHARMACOLOGICAL SCIENCES
- Fatty acid amide hydrolase inhibitors confer anti-invasive and antimetastatic effects on lung cancer cells
- (2016) Katrin Winkler et al. Oncotarget
- Endocannabinoid control of glutamate NMDA receptors: the therapeutic potential and consequences of dysfunction
- (2016) María Rodríguez-Muñoz et al. Oncotarget
- Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer
- (2016) Clara Andradas et al. Oncotarget
- Dual-Acting Compounds Targeting Endocannabinoid and Endovanilloid Systems—A Novel Treatment Option for Chronic Pain Management
- (2016) Natalia Malek et al. Frontiers in Pharmacology
- Role of the endocannabinoid system in diabetes and diabetic complications
- (2015) G Gruden et al. BRITISH JOURNAL OF PHARMACOLOGY
- GPR55 promotes migration and adhesion of colon cancer cells indicating a role in metastasis
- (2015) J Kargl et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor
- (2015) R B Laprairie et al. BRITISH JOURNAL OF PHARMACOLOGY
- Cannabinoid CB1receptors mediate the effects of dipyrone
- (2015) Fernanda Crunfli et al. CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY
- Cannabinoid abuse and addiction: Clinical and preclinical findings
- (2015) LV Panlilio et al. CLINICAL PHARMACOLOGY & THERAPEUTICS
- The antipsychotic aripiprazole induces antinociceptive effects: Possible role of peripheral dopamine D2 and serotonin 5-HT1A receptors
- (2015) Ana F. Almeida-Santos et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- A potential role for cannabinoid receptors in the therapeutic action of fenofibrate
- (2015) Richard S. Priestley et al. FASEB JOURNAL
- Regulation of inflammation by cannabinoids, the endocannabinoids 2-arachidonoyl-glycerol and arachidonoyl-ethanolamide, and their metabolites
- (2015) Caroline Turcotte et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Anandamide-induced endoplasmic reticulum stress and apoptosis are mediated by oxidative stress in non-melanoma skin cancer: Receptor-independent endocannabinoid signaling
- (2015) Eman Soliman et al. MOLECULAR CARCINOGENESIS
- Endocannabinoid signalling in reward and addiction
- (2015) Loren H. Parsons et al. NATURE REVIEWS NEUROSCIENCE
- Cannabinoids in Neurodegenerative Disorders and Stroke/Brain Trauma: From Preclinical Models to Clinical Applications
- (2015) Javier Fernández-Ruiz et al. Neurotherapeutics
- Molecular Targets of Cannabidiol in Neurological Disorders
- (2015) Clementino Ibeas Bih et al. Neurotherapeutics
- CB2 cannabinoid receptor agonist enantiomers HU-433 and HU-308: An inverse relationship between binding affinity and biological potency
- (2015) Reem Smoum et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- In-vivo pharmacological evaluation of the CB1-receptor allosteric modulator Org-27569
- (2014) Thomas F. Gamage et al. BEHAVIOURAL PHARMACOLOGY
- Effects of the cannabinoid CB1 receptor allosteric modulator ORG 27569 on reinstatement of cocaine- and methamphetamine-seeking behavior in rats
- (2014) Li Jing et al. DRUG AND ALCOHOL DEPENDENCE
- AMPK promotes macrophage fatty acid oxidative metabolism to mitigate inflammation: implications for diabetes and cardiovascular disease
- (2014) Gregory R Steinberg et al. IMMUNOLOGY AND CELL BIOLOGY
- Endocannabinoids, Related Compounds and Their Metabolic Routes
- (2014) Filomena Fezza et al. MOLECULES
- The endocannabinoid system: An emotional buffer in the modulation of memory function
- (2014) Maria Morena et al. NEUROBIOLOGY OF LEARNING AND MEMORY
- Monoacylglycerol Lipase Inhibition Blocks Chronic Stress-Induced Depressive-Like Behaviors via Activation of mTOR Signaling
- (2014) Peng Zhong et al. NEUROPSYCHOPHARMACOLOGY
- Endogenous cannabinoid release within prefrontal-limbic pathways affects memory consolidation of emotional training
- (2014) Maria Morena et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cannabinoid CB2receptors modulate midbrain dopamine neuronal activity and dopamine-related behavior in mice
- (2014) Hai-Ying Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Pregnenolone Can Protect the Brain from Cannabis Intoxication
- (2014) Monique Vallée et al. SCIENCE
- Peripherally restricted CB1 receptor blockers
- (2013) Robert J. Chorvat BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNS
- (2013) N Murataeva et al. BRITISH JOURNAL OF PHARMACOLOGY
- Regulation of nausea and vomiting by cannabinoids and the endocannabinoid system
- (2013) Keith A. Sharkey et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Additive antiemetic efficacy of low-doses of the cannabinoid CB1/2 receptor agonist Δ9-THC with ultralow-doses of the vanilloid TRPV1 receptor agonist resiniferatoxin in the least shrew (Cryptotis parva)
- (2013) Nissar A. Darmani et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Allosteric Modulation of a Cannabinoid G Protein-coupled Receptor
- (2013) Derek M. Shore et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Distinct Roles of β-Arrestin 1 and β-Arrestin 2 in ORG27569-induced Biased Signaling and Internalization of the Cannabinoid Receptor 1 (CB1)
- (2013) Kwang H. Ahn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Novelty-Induced Emotional Arousal Modulates Cannabinoid Effects on Recognition Memory and Adrenocortical Activity
- (2013) Patrizia Campolongo et al. NEUROPSYCHOPHARMACOLOGY
- Full Inhibition of Spinal FAAH Leads to TRPV1-Mediated Analgesic Effects in Neuropathic Rats and Possible Lipoxygenase-Mediated Remodeling of Anandamide Metabolism
- (2013) Katarzyna Starowicz et al. PLoS One
- The Endocannabinoid System and Pain
- (2012) Josee Guindon et al. CNS & Neurological Disorders-Drug Targets
- The Endocannabinoid System and the Treatment of Mood and Anxiety Disorders
- (2012) Matthew Hill et al. CNS & Neurological Disorders-Drug Targets
- Involvement of transient receptor potential vanilloid type 1 channels in the pro-convulsant effect of anandamide in pentylenetetrazole-induced seizures
- (2012) Shyamshree S.S. Manna et al. EPILEPSY RESEARCH
- Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models
- (2012) Eric A. Horne et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Nabiximols in the treatment of spasticity, pain and urinary symptoms due to multiple sclerosis
- (2012) Giulio Podda et al. EXPERT OPINION ON BIOLOGICAL THERAPY
- Wired to run: exercise-induced endocannabinoid signaling in humans and cursorial mammals with implications for the 'runner's high'
- (2012) D. A. Raichlen et al. JOURNAL OF EXPERIMENTAL BIOLOGY
- Cannabidiol inhibits THC-elicited paranoid symptoms and hippocampal-dependent memory impairment
- (2012) Amir Englund et al. JOURNAL OF PSYCHOPHARMACOLOGY
- Therapeutic potential of monoacylglycerol lipase inhibitors
- (2012) Melinda M. Mulvihill et al. LIFE SCIENCES
- Neutral antagonism at the cannabinoid 1 receptor: a safer treatment for obesity
- (2012) F J Meye et al. MOLECULAR PSYCHIATRY
- An efficient randomised, placebo-controlled clinical trial with the irreversible fatty acid amide hydrolase-1 inhibitor PF-04457845, which modulates endocannabinoids but fails to induce effective analgesia in patients with pain due to osteoarthritis of the knee
- (2012) John P. Huggins et al. PAIN
- Cellular and intracellular mechanisms involved in the cognitive impairment of cannabinoids
- (2012) E. Puighermanal et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor
- (2012) F. A. Pamplona et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Cannabinoid modulation of noradrenergic circuits: Implications for psychiatric disorders
- (2012) Ana Franky Carvalho et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Cannabinoid receptors: nomenclature and pharmacological principles
- (2012) Linda Console-Bram et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Novel bioactive metabolites of dipyrone (metamizol)
- (2011) Tobias Rogosch et al. BIOORGANIC & MEDICINAL CHEMISTRY
- Δ9-Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells
- (2011) Douglas McHugh et al. BRITISH JOURNAL OF PHARMACOLOGY
- Anti-tumoral action of cannabinoids on hepatocellular carcinoma: role of AMPK-dependent activation of autophagy
- (2011) D Vara et al. CELL DEATH AND DIFFERENTIATION
- Abuse potential and psychoactive effects of δ-9-tetrahydrocannabinol and cannabidiol oromucosal spray (Sativex), a new cannabinoid medicine
- (2011) Philip Robson Expert Opinion On Drug Safety
- Cannabinoid 1 Receptor Blockade Reduces Atherosclerosis with Enhances Reverse Cholesterol Transport
- (2011) Koichi Sugamura et al. Journal of Atherosclerosis and Thrombosis
- Impact of Cannabis Use on Male Sexual Health
- (2011) Rany Shamloul et al. Journal of Sexual Medicine
- Modulation of the serotonin system by endocannabinoid signaling
- (2011) Samir Haj-Dahmane et al. NEUROPHARMACOLOGY
- Neurochemical basis of cannabis addiction
- (2011) R. Maldonado et al. NEUROSCIENCE
- Cannabis with high cannabidiol content is associated with fewer psychotic experiences
- (2011) Christian D. Schubart et al. SCHIZOPHRENIA RESEARCH
- Functionally selective cannabinoid receptor signalling: Therapeutic implications and opportunities
- (2010) Barbara Bosier et al. BIOCHEMICAL PHARMACOLOGY
- Cannabinoid-1 receptor activation induces reactive oxygen species-dependent and -independent mitogen-activated protein kinase activation and cell death in human coronary artery endothelial cells
- (2010) Mohanraj Rajesh et al. BRITISH JOURNAL OF PHARMACOLOGY
- Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
- (2010) Joel E Schlosburg et al. NATURE NEUROSCIENCE
- Depression-like phenotype following chronic CB1 receptor antagonism
- (2010) Chad E. Beyer et al. NEUROBIOLOGY OF DISEASE
- Acetaminophen inhibits status epilepticus in cultured hippocampal neurons
- (2010) Laxmikant S. Deshpande et al. NEUROREPORT
- Seven Transmembrane Receptors as Shapeshifting Proteins: The Impact of Allosteric Modulation and Functional Selectivity on New Drug Discovery
- (2010) T. Kenakin et al. PHARMACOLOGICAL REVIEWS
- Central side-effects of therapies based on CB1 cannabinoid receptor agonists and antagonists: focus on anxiety and depression
- (2009) Fabrício A. Moreira et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Localization and Function of Cannabinoid Receptors in the Corpus Cavernosum: Basis for Modulation of Nitric Oxide Synthase Nerve Activity
- (2009) Christian Gratzke et al. EUROPEAN UROLOGY
- Endocannabinoids render exploratory behaviour largely independent of the test aversiveness: role of glutamatergic transmission
- (2009) W. Jacob et al. GENES BRAIN AND BEHAVIOR
- Receptors for acylethanolamides—GPR55 and GPR119
- (2009) Grzegorz Godlewski et al. PROSTAGLANDINS & OTHER LIPID MEDIATORS
- The role of CB1 receptors in psychostimulant addiction
- (2008) Joost Wiskerke et al. ADDICTION BIOLOGY
- The endocannabinoid system in obesity and type 2 diabetes
- (2008) V. Di Marzo DIABETOLOGIA
- A Role for Intestinal Endocrine Cell-Expressed G Protein-Coupled Receptor 119 in Glycemic Control by Enhancing Glucagon-Like Peptide-1 and Glucose-Dependent Insulinotropic Peptide Release
- (2008) Zhi-Liang Chu et al. ENDOCRINOLOGY
- New Analgesics Synthetically Derived from the Paracetamol MetaboliteN-(4-Hydroxyphenyl)-(5Z,8Z,11Z,14Z)-icosatetra-5,8,11,14-enamide
- (2008) Christian Sinning et al. JOURNAL OF MEDICINAL CHEMISTRY
- Allosteric modulators of GPCRs: a novel approach for the treatment of CNS disorders
- (2008) P. Jeffrey Conn et al. NATURE REVIEWS DRUG DISCOVERY
- Antagonistic cannabinoid CB1/dopamine D2 receptor interactions in striatal CB1/D2 heteromers. A combined neurochemical and behavioral analysis
- (2008) Daniel Marcellino et al. NEUROPHARMACOLOGY
- Pharmacological blockade of the vanilloid receptor TRPV1 elicits marked hyperthermia in humans
- (2008) Narender R. Gavva et al. PAIN
- PSNCBAM-1, a novel allosteric antagonist at cannabinoid CB1 receptors with hypophagic effects in rats
- (2007) J G Horswill et al. BRITISH JOURNAL OF PHARMACOLOGY
- The orphan receptor GPR55 is a novel cannabinoid receptor
- (2007) E Ryberg et al. BRITISH JOURNAL OF PHARMACOLOGY
Discover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversationAdd your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload Now