Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
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Title
Cannabinoid Receptors and the Endocannabinoid System: Signaling and Function in the Central Nervous System
Authors
Keywords
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Journal
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
Volume 19, Issue 3, Pages 833
Publisher
MDPI AG
Online
2018-03-14
DOI
10.3390/ijms19030833
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Note: Only part of the references are listed.- CB1 cannabinoid receptor drives oocyte maturation and embryo development via PI3K/Akt and MAPK pathways
- (2017) Angela Patricia López-Cardona et al. FASEB JOURNAL
- Crystal structures of agonist-bound human cannabinoid receptor CB1
- (2017) Tian Hua et al. NATURE
- Modulation of CB1 cannabinoid receptor by allosteric ligands: Pharmacology and therapeutic opportunities
- (2017) Leepakshi Khurana et al. NEUROPHARMACOLOGY
- The Endogenous Cannabinoid System: A Budding Source of Targets for Treating Inflammatory and Neuropathic Pain
- (2017) Giulia Donvito et al. NEUROPSYCHOPHARMACOLOGY
- Activity-based protein profiling reveals off-target proteins of the FAAH inhibitor BIA 10-2474
- (2017) Annelot C. M. van Esbroeck et al. SCIENCE
- Cannabinoid Receptor Signaling in Central Regulation of Feeding Behavior: A Mini-Review
- (2017) Marco Koch Frontiers in Neuroscience
- FABP1: A Novel Hepatic Endocannabinoid and Cannabinoid Binding Protein
- (2016) Huan Huang et al. BIOCHEMISTRY
- Crystal Structure of the Human Cannabinoid Receptor CB 1
- (2016) Tian Hua et al. CELL
- Cannabis and Cannabinoids
- (2016) JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- High-resolution crystal structure of the human CB1 cannabinoid receptor
- (2016) Zhenhua Shao et al. NATURE
- A cannabinoid link between mitochondria and memory
- (2016) Etienne Hebert-Chatelain et al. NATURE
- Cannabinoid Control of Learning and Memory through HCN Channels
- (2016) Mattia Maroso et al. NEURON
- One for the Price of Two…Are Bivalent Ligands Targeting Cannabinoid Receptor Dimers Capable of Simultaneously Binding to both Receptors?
- (2016) Michelle Glass et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Effects of Cannabis Use on Human Behavior, Including Cognition, Motivation, and Psychosis: A Review
- (2016) Nora D. Volkow et al. JAMA Psychiatry
- Human CB1 Receptor Isoforms, present in Hepatocytes and β-cells, are Involved in Regulating Metabolism
- (2016) Isabel González-Mariscal et al. Scientific Reports
- Cannabinoids in the management of difficult to treat pain
- (2016) Ethan Russo Therapeutics and Clinical Risk Management
- Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor
- (2015) R B Laprairie et al. BRITISH JOURNAL OF PHARMACOLOGY
- The CB1 cannabinoid receptor signals striatal neuroprotection via a PI3K/Akt/mTORC1/BDNF pathway
- (2015) C Blázquez et al. CELL DEATH AND DIFFERENTIATION
- Phytocannabinoids for Cancer Therapeutics: Recent Updates and Future Prospects
- (2015) K.R. Patil et al. CURRENT MEDICINAL CHEMISTRY
- Hypothalamic POMC neurons promote cannabinoid-induced feeding
- (2015) Marco Koch et al. NATURE
- Endocannabinoid signalling and the deteriorating brain
- (2015) Vincenzo Di Marzo et al. NATURE REVIEWS NEUROSCIENCE
- A Cannabinoid CB1 Receptor-Positive Allosteric Modulator Reduces Neuropathic Pain in the Mouse with No Psychoactive Effects
- (2015) Bogna M Ignatowska-Jankowska et al. NEUROPSYCHOPHARMACOLOGY
- Endocannabinoid signaling at the periphery: 50 years after THC
- (2015) Mauro Maccarrone et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Mitochondrial CB1 receptor is involved in ACEA-induced protective effects on neurons and mitochondrial functions
- (2015) Lei Ma et al. Scientific Reports
- Molecular characterization of eluxadoline as a potential ligand targeting mu-delta opioid receptor heteromers
- (2014) Wakako Fujita et al. BIOCHEMICAL PHARMACOLOGY
- Differential Activation of Intracellular versus Plasmalemmal CB2 Cannabinoid Receptors
- (2014) G. Cristina Brailoiu et al. BIOCHEMISTRY
- Endocannabinoid-mediated retrograde modulation of synaptic transmission
- (2014) Takako Ohno-Shosaku et al. CURRENT OPINION IN NEUROBIOLOGY
- Presynaptic Calcium Channel Inhibition Underlies CB1 Cannabinoid Receptor-Mediated Suppression of GABA Release
- (2014) G. G. Szabo et al. JOURNAL OF NEUROSCIENCE
- The endocannabinoid system controls food intake via olfactory processes
- (2014) Edgar Soria-Gómez et al. NATURE NEUROSCIENCE
- Genetic rescue of CB1 receptors on medium spiny neurons prevents loss of excitatory striatal synapses but not motor impairment in HD mice
- (2014) Alipi V. Naydenov et al. NEUROBIOLOGY OF DISEASE
- Species Differences in Cannabinoid Receptor 2 and Receptor Responses to Cocaine Self-Administration in Mice and Rats
- (2014) Hai-Ying Zhang et al. NEUROPSYCHOPHARMACOLOGY
- A restricted population of CB1 cannabinoid receptors with neuroprotective activity
- (2014) A. Chiarlone et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Toward the Development of Bivalent Ligand Probes of Cannabinoid CB1 and Orexin OX1 Receptor Heterodimers
- (2014) David A. Perrey et al. ACS Medicinal Chemistry Letters
- Ligand-specific endocytic dwell times control functional selectivity of the cannabinoid receptor 1
- (2014) Jacqueline Flores-Otero et al. Nature Communications
- Studying mitochondrial CB1 receptors: Yes we can
- (2014) Etienne Hebert-Chatelain et al. Molecular Metabolism
- Cannabinoid control of brain bioenergetics: Exploring the subcellular localization of the CB1 receptor
- (2014) Etienne Hebert-Chatelain et al. Molecular Metabolism
- A tale of two methods: Identifying neuronal CB1 receptors
- (2014) Y.M. Morozov et al. Molecular Metabolism
- Cannabinoid Receptors Couple to NMDA Receptors to Reduce the Production of NO and the Mobilization of Zinc Induced by Glutamate
- (2013) Pilar Sánchez-Blázquez et al. ANTIOXIDANTS & REDOX SIGNALING
- Parsing the players: 2-arachidonoylglycerol synthesis and degradation in the CNS
- (2013) N Murataeva et al. BRITISH JOURNAL OF PHARMACOLOGY
- Distinct Roles of β-Arrestin 1 and β-Arrestin 2 in ORG27569-induced Biased Signaling and Internalization of the Cannabinoid Receptor 1 (CB1)
- (2013) Kwang H. Ahn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Anandamide, Cannabinoid Type 1 Receptor, and NMDA Receptor Activation Mediate Non-Hebbian Presynaptically Expressed Long-Term Depression at the First Central Synapse for Visceral Afferent Fibers
- (2013) A. Khlaifia et al. JOURNAL OF NEUROSCIENCE
- The endocannabinoid signaling system in cancer
- (2013) Simona Pisanti et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- HINT1 protein cooperates with cannabinoid 1 receptor to negatively regulate glutamate NMDA receptor activity
- (2013) Ana Vicente-Sánchez et al. Molecular Brain
- β-Arrestin2 Regulates Cannabinoid CB1 Receptor Signaling and Adaptation in a Central Nervous System Region–Dependent Manner
- (2012) Peter T. Nguyen et al. BIOLOGICAL PSYCHIATRY
- Characterisation of cannabinoid 1 receptor expression in the perikarya, and peripheral and spinal processes of primary sensory neurons
- (2012) Gabor Veress et al. Brain Structure & Function
- Acute Cannabinoids Impair Working Memory through Astroglial CB1 Receptor Modulation of Hippocampal LTD
- (2012) Jing Han et al. CELL
- CB1 Cannabinoid Receptor Activation Rescues Amyloid ß-Induced Alterations in Behaviour and Intrinsic Electrophysiological Properties of Rat Hippocampal CA1 Pyramidal Neurones
- (2012) Masoud Haghani et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Activation-Dependent Subcellular Distribution Patterns of CB1 Cannabinoid Receptors in the Rat Forebrain
- (2012) Karine Thibault et al. CEREBRAL CORTEX
- Downregulation of cannabinoid receptor 1 from neuropeptide Y interneurons in the basal ganglia of patients with Huntington's disease and mouse models
- (2012) Eric A. Horne et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Identification and Quantification of a New Family of Peptide Endocannabinoids (Pepcans) Showing Negative Allosteric Modulation at CB1Receptors
- (2012) Mark Bauer et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Mitochondrial CB1 receptors regulate neuronal energy metabolism
- (2012) Giovanni Bénard et al. NATURE NEUROSCIENCE
- Mitochondrial transport in neurons: impact on synaptic homeostasis and neurodegeneration
- (2012) Zu-Hang Sheng et al. NATURE REVIEWS NEUROSCIENCE
- Endocannabinoid Signaling and Synaptic Function
- (2012) Pablo E. Castillo et al. NEURON
- RGS4 Is Required for Dopaminergic Control of Striatal LTD and Susceptibility to Parkinsonian Motor Deficits
- (2012) Talia N. Lerner et al. NEURON
- Associations between Cannabinoid Receptor-1 (CNR1) Variation and Hippocampus and Amygdala Volumes in Heavy Cannabis Users
- (2012) Joseph P Schacht et al. NEUROPSYCHOPHARMACOLOGY
- Why do cannabinoid receptors have more than one endogenous ligand?
- (2012) V. Di Marzo et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Anti-inflammatory lipoxin A4 is an endogenous allosteric enhancer of CB1 cannabinoid receptor
- (2012) F. A. Pamplona et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Excitability of prefrontal cortical pyramidal neurons is modulated by activation of intracellular type-2 cannabinoid receptors
- (2012) F. S. den Boon et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- At the heart of the matter: the endocannabinoid system in cardiovascular function and dysfunction
- (2012) Fabrizio Montecucco et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Cannabinoid receptor agonists modulate oligodendrocyte differentiation by activating PI3K/Akt and the mammalian target of rapamycin (mTOR) pathways
- (2011) O Gomez et al. BRITISH JOURNAL OF PHARMACOLOGY
- Differential signalling in human cannabinoid CB1 receptors and their splice variants in autaptic hippocampal neurones
- (2011) Alex Straiker et al. BRITISH JOURNAL OF PHARMACOLOGY
- Endocannabinoid Oxygenation by Cyclooxygenases, Lipoxygenases, and Cytochromes P450: Cross-Talk between the Eicosanoid and Endocannabinoid Signaling Pathways
- (2011) Carol A. Rouzer et al. CHEMICAL REVIEWS
- Somatostatin-Dopamine Chimeras: A Novel Approach to Treatment of Neuroendocrine Tumors
- (2011) M. Culler HORMONE AND METABOLIC RESEARCH
- Intracellular Cannabinoid Type 1 (CB1) Receptors Are Activated by Anandamide
- (2011) G. Cristina Brailoiu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Polymodal activation of the endocannabinoid system in the extended amygdala
- (2011) Nagore Puente et al. NATURE NEUROSCIENCE
- Worsening of Huntington disease phenotype in CB1 receptor knockout mice
- (2011) Stéphane Mievis et al. NEUROBIOLOGY OF DISEASE
- The Highs and Lows of Cannabinoid Receptor Expression in Disease: Mechanisms and Their Therapeutic Implications
- (2011) L. K. Miller et al. PHARMACOLOGICAL REVIEWS
- Phytocannabinoids as novel therapeutic agents in CNS disorders
- (2011) Andrew J. Hill et al. PHARMACOLOGY & THERAPEUTICS
- Cannabinoid Receptor 1 trafficking and the role of the intracellular pool: Implications for therapeutics
- (2010) Natasha L. Grimsey et al. BIOCHEMICAL PHARMACOLOGY
- Loss of striatal type 1 cannabinoid receptors is a key pathogenic factor in Huntington’s disease
- (2010) Cristina Blázquez et al. BRAIN
- CB2: a cannabinoid receptor with an identity crisis
- (2010) Brady K Atwood et al. BRITISH JOURNAL OF PHARMACOLOGY
- CB1 Cannabinoid Receptors and their Associated Proteins
- (2010) Allyn Howlett et al. CURRENT MEDICINAL CHEMISTRY
- Diacylglycerol Lipase Is Not Involved in Depolarization-Induced Suppression of Inhibition at Unitary Inhibitory Connections in Mouse Hippocampus
- (2010) R. Min et al. JOURNAL OF NEUROSCIENCE
- Anandamide suppresses pain initiation through a peripheral endocannabinoid mechanism
- (2010) Jason R Clapper et al. NATURE NEUROSCIENCE
- TRPV1 activation by endogenous anandamide triggers postsynaptic long-term depression in dentate gyrus
- (2010) Andrés E Chávez et al. NATURE NEUROSCIENCE
- Bimodal control of stimulated food intake by the endocannabinoid system
- (2010) Luigi Bellocchio et al. NATURE NEUROSCIENCE
- Chronic monoacylglycerol lipase blockade causes functional antagonism of the endocannabinoid system
- (2010) Joel E Schlosburg et al. NATURE NEUROSCIENCE
- Postsynaptic TRPV1 triggers cell type–specific long-term depression in the nucleus accumbens
- (2010) Brad A Grueter et al. NATURE NEUROSCIENCE
- Endocannabinoids Potentiate Synaptic Transmission through Stimulation of Astrocytes
- (2010) Marta Navarrete et al. NEURON
- Regulatory Role of Cannabinoid Receptor 1 in Stress-Induced Excitotoxicity and Neuroinflammation
- (2010) Silvia Zoppi et al. NEUROPSYCHOPHARMACOLOGY
- Behavioural and molecular consequences of chronic cannabinoid treatment in Huntington's disease transgenic mice
- (2010) M.J. Dowie et al. NEUROSCIENCE
- International Union of Basic and Clinical Pharmacology. LXXIX. Cannabinoid Receptors and Their Ligands: Beyond CB1 and CB2
- (2010) R. G. Pertwee et al. PHARMACOLOGICAL REVIEWS
- Cannabinoids and the gut: New developments and emerging concepts
- (2010) Angelo A. Izzo et al. PHARMACOLOGY & THERAPEUTICS
- Cannabinoid-Mediated Inhibition of Recurrent Excitatory Circuitry in the Dentate Gyrus in a Mouse Model of Temporal Lobe Epilepsy
- (2010) Muthu D. Bhaskaran et al. PLoS One
- Type I Cannabinoid Receptor Trafficking: All Roads Lead to Lysosome
- (2010) Raphael Rozenfeld TRAFFIC
- Candidate genes for cannabis use disorders: findings, challenges and directions
- (2009) Arpana Agrawal et al. ADDICTION
- Sensitivity to Δ9-tetrahydrocannabinol is selectively enhanced in beta-arrestin2−/− mice
- (2009) Christopher S. Breivogel et al. BEHAVIOURAL PHARMACOLOGY
- Temporal characterization of changes in hippocampal cannabinoid CB 1 receptor expression following pilocarpine-induced status epilepticus
- (2009) Katherine W. Falenski et al. BRAIN RESEARCH
- The association between cannabinoid receptor 1 gene (CNR1) and cannabis dependence symptoms in adolescents and young adults
- (2009) Christie A. Hartman et al. DRUG AND ALCOHOL DEPENDENCE
- Species differences in cannabinoid receptor 2 (CNR2gene): identification of novel human and rodent CB2 isoforms, differential tissue expression and regulation by cannabinoid receptor ligands
- (2009) Q.-R. Liu et al. GENES BRAIN AND BEHAVIOR
- Signal transduction of the CB1 cannabinoid receptor
- (2009) Gábor Turu et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
- Ligand- and Heterodimer-Directed Signaling of the CB1 Cannabinoid Receptor
- (2009) B. D. Hudson et al. MOLECULAR PHARMACOLOGY
- Self-modulation of neocortical pyramidal neurons by endocannabinoids
- (2009) Silvia Marinelli et al. NATURE NEUROSCIENCE
- Endocannabinoid-Mediated Control of Synaptic Transmission
- (2009) Masanobu Kano et al. PHYSIOLOGICAL REVIEWS
- The psychiatric side-effects of rimonabant
- (2009) Fabrício A. Moreira et al. REVISTA BRASILEIRA DE PSIQUIATRIA
- Non-psychotropic plant cannabinoids: new therapeutic opportunities from an ancient herb
- (2009) Angelo A. Izzo et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Similar in vitro pharmacology of human cannabinoid CB1 receptor variants expressed in CHO cells
- (2008) Jing Chen Xiao et al. BRAIN RESEARCH
- Regulation of CB1 cannabinoid receptor trafficking by the adaptor protein AP-3
- (2008) Raphael Rozenfeld et al. FASEB JOURNAL
- The Endocannabinoid 2-Arachidonoylglycerol Is Responsible for the Slow Self-Inhibition in Neocortical Interneurons
- (2008) S. Marinelli et al. JOURNAL OF NEUROSCIENCE
- Endocannabinoid signaling as a synaptic circuit breaker in neurological disease
- (2008) István Katona et al. NATURE MEDICINE
- Anandamide inhibits metabolism and physiological actions of 2-arachidonoylglycerol in the striatum
- (2008) Mauro Maccarrone et al. NATURE NEUROSCIENCE
- Targeting the endocannabinoid system: to enhance or reduce?
- (2008) Vincenzo Di Marzo NATURE REVIEWS DRUG DISCOVERY
- Endocannabinoids Mediate Neuron-Astrocyte Communication
- (2008) Marta Navarrete et al. NEURON
- Mitochondria in Neuroplasticity and Neurological Disorders
- (2008) Mark P. Mattson et al. NEURON
- Endocannabinoid signaling in microglial cells
- (2008) Nephi Stella NEUROPHARMACOLOGY
- Role of ionotropic cannabinoid receptors in peripheral antinociception and antihyperalgesia
- (2008) Armen N. Akopian et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The cannabinoid CB1 receptor regulates bone formation by modulating adrenergic signaling
- (2007) Joseph Tam et al. FASEB JOURNAL
- Rapid CB1 cannabinoid receptor desensitization defines the time course of ERK1/2 MAP kinase signaling
- (2007) Tanya L. Daigle et al. NEUROPHARMACOLOGY
- Cannabinoid pharmacology: the first 66 years
- (2006) Roger G Pertwee BRITISH JOURNAL OF PHARMACOLOGY
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