Inhibition of Fatty Acid Amide Hydrolase by PF-3845 Alleviates the Nitrergic and Proinflammatory Response in Rat Hippocampus Following Acute Stress

Fatty acid amide hydrolase inhibitors produce rapid anti-anxiety responses through amygdala long-term depression in male rodents

(2017) Tingting Duan et al.   JOURNAL OF PSYCHIATRY & NEUROSCIENCE

Inhibition of ADAM17/TACE activity by zinc-chelating rye secalin-derived tripeptides and analogues

(2017) M. Chinonye Udechukwu et al.   RSC Advances

An update on PPAR activation by cannabinoids

(2016) Saoirse Elizabeth O'Sullivan   BRITISH JOURNAL OF PHARMACOLOGY

Acute restraint stress induces specific changes in nitric oxide production and inflammatory markers in the rat hippocampus and striatum

(2016) Hsiao-Jou Cortina Chen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Acute restraint stress induces rapid changes in central redox status and protective antioxidant genes in rats

(2016) Jereme G. Spiers et al.   PSYCHONEUROENDOCRINOLOGY

Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context

(2015) Patricia Rivera et al.   Frontiers in Cellular Neuroscience

Response of the nitrergic system to activation of the neuroendocrine stress axis

(2015) Hsiao-Jou Cortina Chen et al.   Frontiers in Neuroscience

Harnessing the anti-inflammatory potential of palmitoylethanolamide

(2014) Mireille Alhouayek et al.   DRUG DISCOVERY TODAY

The fatty acid amide hydrolase inhibitor PF-3845 promotes neuronal survival, attenuates inflammation and improves functional recovery in mice with traumatic brain injury

(2014) Flaubert Tchantchou et al.   NEUROPHARMACOLOGY

Substrate-selective COX-2 inhibition as a novel strategy for therapeutic endocannabinoid augmentation

(2014) Daniel J. Hermanson et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Central anandamide deficiency predicts stress-induced anxiety: behavioral reversal through endocannabinoid augmentation

(2014) R J Bluett et al.   Translational Psychiatry

Cyclooxygenase-2-related signaling in the hypothalamus plays differential roles in response to various acute stresses

(2013) Yanbo Ma et al.   BRAIN RESEARCH

Molecular evidence for the involvement of PPAR-δ and PPAR-γ in anti-inflammatory and neuroprotective activities of palmitoylethanolamide after spinal cord trauma

(2013) Irene Paterniti et al.   Journal of Neuroinflammation

PPARγ and stress: Implications for aging

(2012) Yvonne M. Ulrich-Lai et al.   EXPERIMENTAL GERONTOLOGY

Anti-Inflammatory Effect of the Endocannabinoid Anandamide in Experimental Periodontitis and Stress in the Rat

(2012) Elisa Rettori et al.   NEUROIMMUNOMODULATION

Glucocorticoids mediate stress-induced priming of microglial pro-inflammatory responses

(2011) Matthew G. Frank et al.   BRAIN BEHAVIOR AND IMMUNITY

Interleukin-6, a mental cytokine

(2011) Anneleen Spooren et al.   BRAIN RESEARCH REVIEWS

 -Adrenergic Receptor Antagonism Prevents Anxiety-Like Behavior and Microglial Reactivity Induced by Repeated Social Defeat

(2011) E. S. Wohleb et al.   JOURNAL OF NEUROSCIENCE

Recruitment of Prefrontal Cortical Endocannabinoid Signaling by Glucocorticoids Contributes to Termination of the Stress Response

(2011) M. N. Hill et al.   JOURNAL OF NEUROSCIENCE

Prostaglandins mediate depressive-like behaviour induced by endotoxin in mice

(2010) Viviane N. de Paiva et al.   BEHAVIOURAL BRAIN RESEARCH

Non-canonical NF-κB signaling pathway

(2010) Shao-Cong Sun   CELL RESEARCH

ADAM-17: the enzyme that does it all

(2010) Monika Gooz   CRITICAL REVIEWS IN BIOCHEMISTRY AND MOLECULAR BIOLOGY

Cold stress induced morphological microglial activation and increased IL-1β expression in astroglial cells in rat brain

(2010) Shuei Sugama et al.   JOURNAL OF NEUROIMMUNOLOGY

The anti-inflammatory and immunosuppressive effects of glucocorticoids, recent developments and mechanistic insights

(2010) Agnes E. Coutinho et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Gene expression changes in the hypothalamus provide evidence for regionally-selective changes in IL-1 and microglial markers after acute stress

(2009) Peter Blandino et al.   BRAIN BEHAVIOR AND IMMUNITY

The effect of non-steroidal anti-inflammatory agents on behavioural changes and cytokine production following systemic inflammation: Implications for a role of COX-1

(2009) J.L. Teeling et al.   BRAIN BEHAVIOR AND IMMUNITY

Discovery and Characterization of a Highly Selective FAAH Inhibitor that Reduces Inflammatory Pain

(2009) Kay Ahn et al.   CHEMISTRY & BIOLOGY

Signal transduction of the CB1 cannabinoid receptor

(2009) Gábor Turu et al.   JOURNAL OF MOLECULAR ENDOCRINOLOGY

Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain

(2009) Carol A. Colton   Journal of Neuroimmune Pharmacology

The Stressed CNS: When Glucocorticoids Aggravate Inflammation

(2009) Shawn F. Sorrells et al.   NEURON

Suppression of Amygdalar Endocannabinoid Signaling by Stress Contributes to Activation of the Hypothalamic–Pituitary–Adrenal Axis

(2009) Matthew N Hill et al.   NEUROPSYCHOPHARMACOLOGY

Differential microglial activation between acute stress and lipopolysaccharide treatment

(2008) Shuei Sugama et al.   JOURNAL OF NEUROIMMUNOLOGY

Endocannabinoid signaling in microglial cells

(2008) Nephi Stella   NEUROPHARMACOLOGY

Conditional cannabinoid receptor type 1 mutants reveal neuron subpopulation-specific effects on behavioral and neuroendocrine stress responses

(2008) Michel A. Steiner et al.   PSYCHONEUROENDOCRINOLOGY

Stress Mediators Regulate Brain Prostaglandin Synthesis and Peroxisome Proliferator-Activated Receptor-γ Activation after Stress in Rats

(2007) Borja García-Bueno et al.   ENDOCRINOLOGY