Effect of TRPV1 Antagonist SC0030, a Potent Painkiller, on RANKL‐mediated Osteoclast Differentiation Involved in Bone Resorption

Osteoporosis treatment: recent developments and ongoing challenges

(2017) Sundeep Khosla et al.   Lancet Diabetes & Endocrinology

RANK-RANKL signalling in cancer

(2016) N. Renema et al.   BIOSCIENCE REPORTS

Clinical challenges in the management of osteoporosis

(2016) Sheryl Vondracek   Clinical Interventions in Aging

Osteoclasts: more than ‘bone eaters’

(2014) Julia F. Charles et al.   TRENDS IN MOLECULAR MEDICINE

The Concise Guide to PHARMACOLOGY 2013/14: Ion Channels

(2013) Stephen P.H. Alexander et al.   BRITISH JOURNAL OF PHARMACOLOGY

Impact of osteoporosis and bone fracture on health-related quality of life in postmenopausal women

(2013) S. Palacios et al.   CLIMACTERIC

Nitric oxide induces apoptosis associated with TRPV1 channel-mediated Ca2+ entry via S-nitrosylation in osteoblasts

(2013) Leiting Pan et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Heterocycle-linked Phenylbenzyl Amides as Novel TRPV1 Antagonists and Their TRPV1 Binding Modes: Constraint-Induced Enhancement of In Vitro and In Vivo Activities

(2012) Nam-Jung Kim et al.   Chemistry-An Asian Journal

RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy Receptor

(2012) Christopher A. Nelson et al.   STRUCTURE

Osteoporosis: now and the future

(2011) Tilman D Rachner et al.   LANCET

The TRPV1 ion channel antagonist capsazepine inhibits osteoclast and osteoblast differentiation in vitro and ovariectomy induced bone loss in vivo

(2010) Aymen I. Idris et al.   BONE

Selective targeting of RANK signaling pathways as new therapeutic strategies for osteoporosis

(2010) Joel Jules et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

Structural and Functional Insights of RANKL-RANK Interaction and Signaling

(2010) C. Liu et al.   JOURNAL OF IMMUNOLOGY

Synthesis and structural optimization of multiple H-bonding region of diarylalkyl (thio)amides as novel TRPV1 antagonists

(2009) Fu-Nan Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Design, synthesis, and biological evaluation of novel diarylalkyl amides as TRPV1 antagonists

(2009) Fu-Nan Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

RANKL induces heterogeneous DC-STAMPloand DC-STAMPhiosteoclast precursors of which the DC-STAMPloprecursors are the master fusogens

(2009) Kofi A. Mensah et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The endovanilloid/endocannabinoid system in human osteoclasts: Possible involvement in bone formation and resorption

(2008) F. Rossi et al.   BONE

Expression of ion channels of the TRP family in articular chondrocytes from osteoarthritic patients: changes between native and in vitro propagated chondrocytes

(2008) K. Gavenis et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Cannabinoid receptors and the regulation of bone mass

(2007) I Bab et al.   BRITISH JOURNAL OF PHARMACOLOGY