Atypical cannabinoid ligands O-1602 and O-1918 administered chronically in diet-induced obesity

GPR55 deficiency is associated with increased adiposity and impaired insulin signaling in peripheral metabolic tissues

(2018) Christopher Lipina et al.   FASEB JOURNAL

Efficacy and Safety of Cannabidiol and Tetrahydrocannabivarin on Glycemic and Lipid Parameters in Patients With Type 2 Diabetes: A Randomized, Double-Blind, Placebo-Controlled, Parallel Group Pilot Study

(2016) Khalid A. Jadoon et al.   DIABETES CARE

Metabolic effects of orally administered small-molecule agonists of GPR55 and GPR119 in multiple low-dose streptozotocin-induced diabetic and incretin-receptor-knockout mice

(2016) Aine M. McKillop et al.   DIABETOLOGIA

Cannabidiol promotes browning in 3T3-L1 adipocytes

(2016) Hilal Ahmad Parray et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Renal effects of chronic pharmacological manipulation of CB2receptors in rats with diet-induced obesity

(2015) K A Jenkin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Deletion of G-protein-coupled receptor 55 promotes obesity by reducing physical activity

(2015) A Meadows et al.   INTERNATIONAL JOURNAL OF OBESITY

Chronic administration of AM251 improves albuminuria and renal tubular structure in obese rats

(2015) K. A. Jenkin et al.   JOURNAL OF ENDOCRINOLOGY

Acute leptin exposure reduces megalin expression and upregulates TGFβ1 in cultured renal proximal tubule cells

(2015) Jessica F. Briffa et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Correction: Activation of GPR55 Receptors Exacerbates oxLDL-Induced Lipid Accumulation and Inflammatory Responses, while Reducing Cholesterol Efflux from Human Macrophages

(2015) Mirko Lanuti et al.   PLoS One

Activation of GPR18 by cannabinoid compounds: a tale of biased agonism

(2014) Linda Console-Bram et al.   BRITISH JOURNAL OF PHARMACOLOGY

Regulation of GPR55 in rat white adipose tissue and serum LPI by nutritional status, gestation, gender and pituitary factors

(2014) Monica Imbernon et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Increase of mesenchymal stem cell migration by cannabidiol via activation of p42/44 MAPK

(2013) Ellen Schmuhl et al.   BIOCHEMICAL PHARMACOLOGY

Cannabidiol provides long-lasting protection against the deleterious effects of inflammation in a viral model of multiple sclerosis: A role for A2A receptors

(2013) M. Mecha et al.   NEUROBIOLOGY OF DISEASE

A role for O-1602 and G protein-coupled receptor GPR55 in the control of colonic motility in mice

(2013) Kun Li et al.   NEUROPHARMACOLOGY

Na+-H+ Exchanger Regulatory Factor 1 (NHERF1) PDZ Scaffold Binds an Internal Binding Site in the Scavenger Receptor Megalin

(2012) Craig Slattery et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

A potential role for GPR55 in gastrointestinal functions

(2012) Rudolf Schicho et al.   CURRENT OPINION IN PHARMACOLOGY

O-1602, an atypical cannabinoid, inhibits tumor growth in colitis-associated colon cancer through multiple mechanisms

(2012) Julia Kargl et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Interactive effects of neonatal exposure to monosodium glutamate and aspartame on glucose homeostasis

(2012) Kate S Collison et al.   Nutrition & Metabolism

Anti-Inflammatory Role of Cannabidiol and O-1602 in Cerulein-Induced Acute Pancreatitis in Mice

(2012) Kun Li et al.   PANCREAS

Evidence for the Putative Cannabinoid Receptor (GPR55)-Mediated Inhibitory Effects on Intestinal Contractility in Mice

(2012) Gracious R. Ross et al.   PHARMACOLOGY

Δ9-Tetrahydrocannabinol and N-arachidonyl glycine are full agonists at GPR18 receptors and induce migration in human endometrial HEC-1B cells

(2011) Douglas McHugh et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role for Cannabinoid Receptors in Human Proximal Tubular Hypertrophy

(2011) Kayte A. Jenkin et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The L- -Lysophosphatidylinositol/GPR55 System and Its Potential Role in Human Obesity

(2011) J. M. Moreno-Navarrete et al.   DIABETES

The atypical cannabinoid O-1602 stimulates food intake and adiposity in rats

(2011) A. Díaz-Arteaga et al.   DIABETES OBESITY & METABOLISM

Cannabinoid receptor 1 (CB1) antagonism enhances glucose utilisation and activates brown adipose tissue in diet-induced obese mice

(2011) M. Bajzer et al.   DIABETOLOGIA

Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress

(2011) George W. Booz   FREE RADICAL BIOLOGY AND MEDICINE

The abnormal cannabidiol analogue O-1602 reduces nociception in a rat model of acute arthritis via the putative cannabinoid receptor GPR55

(2011) Niklas Schuelert et al.   NEUROSCIENCE LETTERS

N-arachidonoyl glycine, an abundant endogenous lipid, potently drives directed cellular migration through GPR18, the putative abnormal cannabidiol receptor

(2010) Douglas McHugh et al.   BMC NEUROSCIENCE

The atypical cannabinoid O-1602 protects against experimental colitis and inhibits neutrophil recruitment

(2010) Rudolf Schicho et al.   INFLAMMATORY BOWEL DISEASES

The endocannabinoid system: Its roles in energy balance and potential as a target for obesity treatment

(2010) Aurore André et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Role of insulin as a negative regulator of plasma endocannabinoid levels in obese and nonobese subjects

(2009) Vincenzo Di Marzo et al.   EUROPEAN JOURNAL OF ENDOCRINOLOGY

The putative cannabinoid receptor GPR55 affects osteoclast function in vitro and bone mass in vivo

(2009) L. S. Whyte et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The endocannabinoid system in obesity and type 2 diabetes

(2008) V. Di Marzo   DIABETOLOGIA

2-Arachidonoylglycerol elicits neuroprotective effects on excitotoxically lesioned dentate gyrus granule cells via abnormal-cannabidiol-sensitive receptors on microglial cells

(2008) Susanne Kreutz et al.   GLIA

The diverse CB1and CB2receptor pharmacology of three plant cannabinoids: Δ9-tetrahydrocannabinol, cannabidiol and Δ9-tetrahydrocannabivarin

(2007) R G Pertwee   BRITISH JOURNAL OF PHARMACOLOGY