Polyphenolic Compounds and Digestive Enzymes: In Vitro Non-Covalent Interactions

Comparison of α-amylase, α-glucosidase and lipase inhibitory activity of the phenolic substances in two black legumes of different genera

(2017) Yuqing Tan et al.   FOOD CHEMISTRY

Comparison of binding interaction between β-lactoglobulin and three common polyphenols using multi-spectroscopy and modeling methods

(2017) Jingjing Jia et al.   FOOD CHEMISTRY

Proanthocyanidins from the kernel and shell of pecan (Carya illinoinensis): Average degree of polymerization and effects on carbohydrate, lipid, and peptide hydrolysis in a simulated human digestive system

(2017) A.A. Vazquez-Flores et al.   Journal of Functional Foods

Dihydropyrano [2,3-c] pyrazole: Novel in vitro inhibitors of yeast α -glucosidase

(2016) Hamdy Kashtoh et al.   BIOORGANIC CHEMISTRY

Polyphenols rich fraction from Geoffroea decorticans fruits flour affects key enzymes involved in metabolic syndrome, oxidative stress and inflammatory process

(2016) M.S. Costamagna et al.   FOOD CHEMISTRY

Dynamic modeling of in vitro lipid digestion: Individual fatty acid release and bioaccessibility kinetics

(2016) T.M. Giang et al.   FOOD CHEMISTRY

Distribution of phenolic antioxidants in whole and milled fractions of quinoa and their inhibitory effects on α-amylase and α-glucosidase activities

(2016) P. Hemalatha et al.   FOOD CHEMISTRY

Small intestine mucosal α-glucosidase: A missing feature of in vitro starch digestibility

(2016) Amy Hui-Mei Lin et al.   FOOD HYDROCOLLOIDS

α-Glucosidase and α-amylase inhibitors from Myrcia spp.: a stronger alternative to acarbose?

(2016) María Figueiredo-González et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

Effects of tea polyphenols and different teas on pancreatic α-amylase activity in vitro

(2016) Xiaoping Yang et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

From carbohydrates to drug-like fragments: Rational development of novel α-amylase inhibitors

(2015) Jamil Al-Asri et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Flavonoid interactions during digestion, absorption, distribution and metabolism: a sequential structure–activity/property relationship-based approach in the study of bioavailability and bioactivity

(2015) Gerard Bryan Gonzales et al.   DRUG METABOLISM REVIEWS

The mechanism study in the interactions of sorghum procyanidins trimer with porcine pancreatic α-amylase

(2015) Xin Cai et al.   FOOD CHEMISTRY

Simulated gastrointestinal digestion, intestinal permeation and plasma protein interaction of white, green, and black tea polyphenols

(2015) Gian Carlo Tenore et al.   FOOD CHEMISTRY

Interactions of polyphenols with carbohydrates, lipids and proteins

(2015) Lidija Jakobek   FOOD CHEMISTRY

Effect of inclusion of hydroxycinnamic and chlorogenic acids from green coffee bean in β-cyclodextrin on their interactions with whey, egg white and soy protein isolates

(2015) Grażyna Budryn et al.   FOOD CHEMISTRY

Phenolic profiles of 20 Canadian lentil cultivars and their contribution to antioxidant activity and inhibitory effects on α-glucosidase and pancreatic lipase

(2015) Bing Zhang et al.   FOOD CHEMISTRY

Comparative evaluation of tannic acid inhibiting α-glucosidase and trypsin

(2015) Huizhi Xiao et al.   FOOD RESEARCH INTERNATIONAL

Caffeoylquinic acids competitively inhibit pancreatic lipase through binding to the catalytic triad

(2015) Bing Hu et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Gastro-pancreatic release of phenolic compounds incorporated in a polyphenols-enriched cheese-curd

(2015) Ahmed Helal et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Polyphenolic Compounds as Pancreatic Lipase Inhibitors

(2015) Tina Buchholz et al.   PLANTA MEDICA

Molecular interactions of flavonoids to pepsin: Insights from spectroscopic and molecular docking studies

(2015) Hua-jin Zeng et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

Hepatic genome-wide expression of lipid metabolism in diet-induced obesity rats treated with cocoa polyphenols

(2015) Faisal Ali et al.   Journal of Functional Foods

Polyphenol interactions with whey protein isolate and whey protein isolate–pectin coacervates

(2014) Chutima Thongkaew et al.   FOOD HYDROCOLLOIDS

In Vitro Inhibitory Effect on Digestive Enzymes and Antioxidant Potential of Commonly Consumed Fruits

(2014) Anna Podsędek et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Anti-obesity and cardioprotective effects of cinnamic acid in high fat diet- induced obese rats

(2014) Kais Mnafgui et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Composition and inhibitory activities towards digestive enzymes of polyphenolic-rich fractions of Davidson's plum and quandong

(2014) Karunrat Sakulnarmrat et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Molecular Interactions between (−)-Epigallocatechin Gallate Analogs and Pancreatic Lipase

(2014) Shihui Wang et al.   PLoS One

Pancreatic α-amylase and lipase inhibitory activity of polyphenolic compounds present in the extract of black chokeberry (Aronia melanocarpa L.)

(2014) Paulina Worsztynowicz et al.   PROCESS BIOCHEMISTRY

Bioaccessibility of polyphenols and cinnamaldehyde in cinnamon beverages subjected to in vitro gastro-pancreatic digestion

(2014) Ahmed Helal et al.   Journal of Functional Foods

Crystal structure of a compact α-amylase from Geobacillus thermoleovorans

(2013) Sook-Chen Mok et al.   ENZYME AND MICROBIAL TECHNOLOGY

Phytonutrients for controlling starch digestion: Evaluation of grape skin extract

(2013) Ming Miao et al.   FOOD CHEMISTRY

Bound phenolics in foods, a review

(2013) Beatriz A. Acosta-Estrada et al.   FOOD CHEMISTRY

Acteoside: A lipase inhibitor from the Chinese tea Ligustrum purpurascens kudingcha

(2013) Xuli Wu et al.   FOOD CHEMISTRY

Phenylpropanoid glycoside inhibition of pepsin, trypsin and α-chymotrypsin enzyme activity in Kudingcha leaves from Ligustrum purpurascens

(2013) Xuli Wu et al.   FOOD RESEARCH INTERNATIONAL

A review on protein–phenolic interactions and associated changes

(2013) Tugba Ozdal et al.   FOOD RESEARCH INTERNATIONAL

Inhibition of salivary and pancreatic α-amylases by a pinhão coat (Araucaria angustifolia) extract rich in condensed tannin

(2013) Simone Mariano da Silva et al.   FOOD RESEARCH INTERNATIONAL

Interaction between four flavonoids and trypsin: effect on the characteristics of trypsin and antioxidant activity of flavonoids

(2013) Qiong Li et al.   INTERNATIONAL JOURNAL OF FOOD SCIENCE AND TECHNOLOGY

Inhibition of pancreatic lipase, α-glucosidase, α-amylase, and hypolipidemic effects of the total flavonoids from Nelumbo nucifera leaves

(2013) Song Liu et al.   JOURNAL OF ETHNOPHARMACOLOGY

Structural properties of the truncated and wild types of Taka-amylase: A molecular dynamics simulation and docking study

(2013) Mohammad Reza Housaindokht et al.   JOURNAL OF MOLECULAR CATALYSIS B-ENZYMATIC

Measurements of Salivary Alpha Amylase and Salivary Cortisol in Hominoid Primates Reveal Within-Species Consistency and Between-Species Differences

(2013) Verena Behringer et al.   PLoS One

Effects of proanthocyanidins on porcine pancreatic lipase: Conformation, activity, kinetics and thermodynamics

(2013) Shihui Wang et al.   PROCESS BIOCHEMISTRY

Weight Loss Strategies for Treatment of Obesity

(2013) Robert F. Kushner   PROGRESS IN CARDIOVASCULAR DISEASES

Characterisation of thermostable trypsin and determination of trypsin isozymes from intestine of Nile tilapia (Oreochromis niloticus L.)

(2012) Sasimanas Unajak et al.   FOOD CHEMISTRY

Composition of native Australian herbs polyphenolic-rich fractions and in vitro inhibitory activities against key enzymes relevant to metabolic syndrome

(2012) Karunrat Sakulnarmrat et al.   FOOD CHEMISTRY

Phenolic compounds and plant extracts as potential natural anti-obesity substances

(2012) Thérèse Sergent et al.   FOOD CHEMISTRY

Interactions of different polyphenols with bovine serum albumin using fluorescence quenching and molecular docking

(2012) Mihaela Skrt et al.   FOOD CHEMISTRY

Phenolic contents, antioxidant capacities and inhibitory activities against key metabolic syndrome relevant enzymes of herbal teas from Eastern Anatolia

(2012) Abdullah Dalar et al.   INDUSTRIAL CROPS AND PRODUCTS

Effect of gallic acid on peptides released by trypsin digestion of bovine α-casein

(2012) Ping Lai et al.   JOURNAL OF BIOSCIENCE AND BIOENGINEERING

Flavonoid interactions with human transthyretin: Combined structural and thermodynamic analysis

(2012) Daniela B.B. Trivella et al.   JOURNAL OF STRUCTURAL BIOLOGY

Interactions between Polyphenols and Macromolecules: Quantification Methods and Mechanisms

(2011) C. Le Bourvellec et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Probing the interaction between 3 flavonoids and pancreatic lipase by methods of fluorescence spectroscopy and enzymatic kinetics

(2011) Yan-Qin Li et al.   EUROPEAN FOOD RESEARCH AND TECHNOLOGY

Soybean phenolic-rich extracts inhibit key-enzymes linked to type 2 diabetes (α-amylase and α-glucosidase) and hypertension (angiotensin I converting enzyme) in vitro

(2011) Adedayo O. Ademiluyi et al.   EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY

Inhibitory effects of chlorogenic acids from green coffee beans and cinnamate derivatives on the activity of porcine pancreas α-amylase isozyme I

(2011) Yusaku Narita et al.   FOOD CHEMISTRY

Milk β-lactoglobulin complexes with tea polyphenols

(2011) C.D. Kanakis et al.   FOOD CHEMISTRY

Mechanisms of Tannin-Induced Trypsin Inhibition: A Molecular Approach

(2011) Rui Gonçalves et al.   LANGMUIR

Anti-diabetic activities of phenolic compounds in muscadine against alpha-glucosidase and pancreatic lipase

(2011) Qi You et al.   LWT-FOOD SCIENCE AND TECHNOLOGY

Synthesis and α-Glucosidase Inhibitory Mechanisms of Bis(2,3-dibromo-4,5-dihydroxybenzyl) Ether, a Potential Marine Bromophenol α-Glucosidase Inhibitor

(2011) Ming Liu et al.   Marine Drugs

In Vitro Inhibitory Effects of Cyandin-3-rutinoside on Pancreatic α-Amylase and Its Combined Effect with Acarbose

(2011) Sarinya Akkarachiyasit et al.   MOLECULES

Dietary phytochemicals and their potential effects on obesity: A review

(2011) Marta González-Castejón et al.   PHARMACOLOGICAL RESEARCH

Antiobesity and lipid lowering effects of Glycyrrhiza chalcones: Experimental and computational studies

(2011) Rahul B. Birari et al.   PHYTOMEDICINE

Analysis of binding interaction between (−)-epigallocatechin (EGC) and β-lactoglobulin by multi-spectroscopic method

(2011) Xuli Wu et al.   SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY

α-Glucosidase and α-amylase inhibitory activities of guava leaves

(2010) Hui Wang et al.   FOOD CHEMISTRY

Inhibition of α-amylase activity by condensed tannins

(2010) Rui Gonçalves et al.   FOOD CHEMISTRY

In vitro human digestion models for food applications

(2010) Sun Jin Hur et al.   FOOD CHEMISTRY

Anti-proliferative and potential anti-diabetic effects of phenolic-rich extracts from edible marine algae

(2010) Felix Nwosu et al.   FOOD CHEMISTRY

White and green tea polyphenols inhibit pancreatic lipase in vitro

(2010) Anais Gondoin et al.   FOOD RESEARCH INTERNATIONAL

Structures of human pancreatic α-amylase in complex with acarviostatins: Implications for drug design against type II diabetes

(2010) Xiaohong Qin et al.   JOURNAL OF STRUCTURAL BIOLOGY

Prevention of diet-induced obesity by dietary black tea polyphenols extract in vitro and in vivo

(2010) Satoshi Uchiyama et al.   NUTRITION

Crystallographic study of the structure of colipase and of the interaction with pancreatic lipase

(2010) Marie-Pierre Egloff et al.   PROTEIN SCIENCE

Toxic effect of melanoidins from glucose–asparagine on trypsin activity

(2009) Albert Ibarz et al.   FOOD AND CHEMICAL TOXICOLOGY

Composition and enzyme inhibitory properties of finger millet (Eleusine coracana L.) seed coat phenolics: Mode of inhibition of α-glucosidase and pancreatic amylase

(2009) S. Shobana et al.   FOOD CHEMISTRY

Characterization of binding interactions between green tea flavanoids and milk proteins

(2009) Zerrin Yuksel et al.   FOOD CHEMISTRY

Natural Phenolic Compounds From Medicinal Herbs and Dietary Plants: Potential Use for Cancer Prevention

(2009) Wu-Yang Huang et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Kinetics study on a novel natural inhibitor of α-chymotrypsin

(2008) Viqar Uddin Ahmad et al.   FITOTERAPIA

Enhancement of digestive enzymatic activity by cumin (Cuminum cyminum L.) and role of spent cumin as a bionutrient

(2008) K.S. Muthamma Milan et al.   FOOD CHEMISTRY

Berry polyphenols inhibit pancreatic lipase activity in vitro

(2008) Gordon J. McDougall et al.   FOOD CHEMISTRY

α-Glucosidase and α-amylase inhibitory activities of Nepalese medicinal herb Pakhanbhed (Bergenia ciliata, Haw.)

(2007) Megh Raj Bhandari et al.   FOOD CHEMISTRY

Human Intestinal Maltase–Glucoamylase: Crystal Structure of the N-Terminal Catalytic Subunit and Basis of Inhibition and Substrate Specificity

(2007) Lyann Sim et al.   JOURNAL OF MOLECULAR BIOLOGY