Research progress in understanding the biosynthesis and regulation of plant anthocyanins

Drought‐induced CsMYB6 interacts with CsbHLH111 to regulate anthocyanin biosynthesis in Chaenomeles speciosa

(2023) Shuangyu Zhang et al.   PHYSIOLOGIA PLANTARUM

Mdm‐miR858 targets MdMYB9 and MdMYBPA1 to participate anthocyanin biosynthesis in red‐fleshed apple

(2023) Zhiqiang Li et al.   PLANT JOURNAL

Two genes, ANS and UFGT2, from Vaccinium spp. are key steps for modulating anthocyanin production

(2023) Han M. Nguyen et al.   Frontiers in Plant Science

PlgMYBR1, an R2R3-MYB transcription factor, plays as a negative regulator of anthocyanin biosynthesis in Platycodon grandiflorus

(2023) Eunhui Kim et al.   3 Biotech

Genome-wide identification of WD40 transcription factors and their regulation of the MYB-bHLH-WD40 (MBW) complex related to anthocyanin synthesis in Qingke (Hordeum vulgare L. var. nudum Hook. f.)

(2023) Lin Chen et al.   BMC GENOMICS

Integrated transcriptomic and metabolomic profiles reveal anthocyanin accumulation in Scutellaria baicalensis petal coloration

(2023) Suying Hu et al.   INDUSTRIAL CROPS AND PRODUCTS

Safflower Flavonoid 3′5′Hydroxylase Promotes Methyl Jasmonate-induced Anthocyanin Accumulation in Transgenic Plants

(2023) Xinyue Zhang et al.   MOLECULES

The E3 ubiquitin ligases SINA1 and SINA2 integrate with the protein kinase CIPK20 to regulate the stability of RGL2a, a positive regulator of anthocyanin biosynthesis

(2023) Jian‐Ping An et al.   NEW PHYTOLOGIST

A novel R2R3‐MYB transcription factor FaMYB5 positively regulates anthocyanin and proanthocyanidin biosynthesis in cultivated strawberries (Fragaria × ananassa)

(2023) Leiyu Jiang et al.   PLANT BIOTECHNOLOGY JOURNAL

The bZIP transcription factor SlAREB1 regulates anthocyanin biosynthesis in response to low temperature in tomato

(2023) Zijian Xu et al.   PLANT JOURNAL

Genome–Transcriptome Transition Approaches to Characterize Anthocyanin Biosynthesis Pathway Genes in Blue, Black and Purple Wheat

(2023) Payal Kapoor et al.   Genes

Biosynthesis and regulation of anthocyanin pathway genes

(2022) L. Sunil et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Genome-Wide Identification and Comparative Profiling of MicroRNAs Reveal Flavonoid Biosynthesis in Two Contrasting Flower Color Cultivars of Tree Peony

(2022) Xiaoning Luo et al.   Frontiers in Plant Science

Transcriptome Analysis of Apples in High-Temperature Treatments Reveals a Role of MdLBD37 in the Inhibition of Anthocyanin Accumulation

(2022) Yu-Feng Bu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Functional Characterization of Flavanone 3-Hydroxylase (F3H) and Its Role in Anthocyanin and Flavonoid Biosynthesis in Mulberry

(2022) Mingjie Dai et al.   MOLECULES

Apple MdMYB306 ‐like inhibits anthocyanin synthesis by directly interacting with MdMYB17 and MdbHLH33

(2022) Shuo Wang et al.   PLANT JOURNAL

Functional characterization of chalcone isomerase gene HvCHI revealing its role in anthocyanin accumulation in Hosta ventricosa

(2022) Qin Shijie et al.   Brazilian Journal of Botany

The WKRY transcription factor MdWRKY75 regulates anthocyanins accumulation in apples (

(2022) Mengyu Su et al.   FUNCTIONAL PLANT BIOLOGY

The Ethylene Response Factor ERF5 Regulates Anthocyanin Biosynthesis in ‘Zijin’ Mulberry Fruits by Interacting with MYBA and F3H Genes

(2022) Rongli Mo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Discovery of a DFR gene that controls anthocyanin accumulation in the spiny Solanum group: roles of a natural promoter variant and alternative splicing

(2022) Xing Wang et al.   PLANT JOURNAL

ARF2 positively regulates flavonols and proanthocyanidins biosynthesis in Arabidopsis thaliana

(2022) Wenbo Jiang et al.   PLANTA

ABA-mediated miR5290 promotes anthocyanin biosynthesis by inhibiting the expression of FaMADS1 in postharvest strawberry fruit

(2022) Renchi Chen et al.   POSTHARVEST BIOLOGY AND TECHNOLOGY

The joint role of the late anthocyanin biosynthetic UFGT-encoding genes in the flowers and fruits coloration of horticultural plants

(2022) Noor Muhammad et al.   SCIENTIA HORTICULTURAE

Characterization of phenylalanine ammonia-lyase genes facilitating flavonoid biosynthesis from two species of medicinal plant Anoectochilus

(2022) Lin Yang et al.   PeerJ

Research progress about microRNAs involved in plant secondary metabolism

(2022) Shanshan Zhang et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Characteristics of bHLH transcription factors and their roles in the abiotic stress responses of horticultural crops

(2022) Kangning Wang et al.   SCIENTIA HORTICULTURAE

Omic analysis of anthocyanin synthesis in wine grape leaves under low-temperature

(2022) Qianqian Pang et al.   SCIENTIA HORTICULTURAE

Interaction of AcMADS68 with transcription factors regulates anthocyanin biosynthesis in red-fleshed kiwifruit

(2022) Yanfei Liu et al.   Horticulture Research

Polyphenols and Human Health: The Role of Bioavailability

(2021) Chiara Di Lorenzo et al.   Nutrients

Multifunctional evolution of B and AGL6 MADS box genes in orchids

(2021) Hsing-Fun Hsu et al.   Nature Communications

MYB-Mediated Regulation of Anthocyanin Biosynthesis

(2021) Huiling Yan et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Functional characterization of two chalcone isomerase (CHI) revealing their responsibility for anthocyanins accumulation in mulberry

(2021) Nan Chao et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

Regulatory Mechanisms of Anthocyanin Biosynthesis in Apple and Pear

(2021) Huimin Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Emerging roles of brassinosteroids and light in anthocyanin biosynthesis and ripeness of climacteric and non-climacteric fruits

(2021) Ni Yang et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Light Induced Regulation Pathway of Anthocyanin Biosynthesis in Plants

(2021) Yanyun Ma et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

ECAP is a key negative regulator mediating different pathways to modulate salt stress‐induced anthocyanin biosynthesis in Arabidopsis

(2021) Changjiang Li et al.   NEW PHYTOLOGIST

Review: The effects of hormones and environmental factors on anthocyanin biosynthesis in apple

(2021) Huai-Na Gao et al.   PLANT SCIENCE

Transcriptome Analysis Revealed the Mechanism by Which Exogenous ABA Increases Anthocyanins in Blueberry Fruit During Veraison

(2021) Tianyu Han et al.   Frontiers in Plant Science

Physiological evaluation for salt tolerance in green and purple leaf color rice cultivars at seedling stage

(2021) Noppawan Nounjan et al.   PHYSIOLOGY AND MOLECULAR BIOLOGY OF PLANTS

Ethylene Induced by Sound Stimulation Enhances Anthocyanin Accumulation in Grape Berry Skin through Direct Upregulation of UDP-Glucose: Flavonoid 3-O-Glucosyltransferase

(2021) Mone Yamazaki et al.   Cells

FvbHLH9, functions as a positive regulator of anthocyanin biosynthesis, by forming HY5-bHLH9 transcription complex in strawberry fruits

(2020) Yang Li et al.   PLANT AND CELL PHYSIOLOGY

Exogenous Abscisic Acid Regulates Distribution of 13C and 15N and Anthocyanin Synthesis in ‘Red Fuji’ Apple Fruit Under High Nitrogen Supply

(2020) Fen Wang et al.   Frontiers in Plant Science

Expression of the subgroup IIIf bHLH transcription factor CpbHLH1 from Chimonanthus praecox (L.) in transgenic model plants inhibits anthocyanin accumulation

(2020) Rong Zhao et al.   PLANT CELL REPORTS

A blueberry MIR156a–SPL12 module coordinates the accumulation of chlorophylls and anthocyanins during fruit ripening

(2020) Xuyan Li et al.   JOURNAL OF EXPERIMENTAL BOTANY

MicroRNA858 negatively regulates anthocyanin biosynthesis by repressing AaMYBC1 expression in kiwifruit (Actinidia arguta)

(2020) Yukuo Li et al.   PLANT SCIENCE

MiR156 regulates anthocyanin biosynthesis through SPL targets and other microRNAs in poplar

(2020) Yamei Wang et al.   Horticulture Research

Functional and correlation analyses of dihydroflavonol-4-reductase genes indicate their roles in regulating anthocyanin changes in Ginkgo biloba

(2020) Jun Ni et al.   INDUSTRIAL CROPS AND PRODUCTS

The R2R3-MYB transcription factor MiMYB1 regulates light dependent red coloration of ‘Irwin’ mango fruit skin

(2020) Shinya Kanzaki et al.   SCIENTIA HORTICULTURAE

Functional analysis of an anthocyanin synthase gene StANS in potato

(2020) Huiling Zhang et al.   SCIENTIA HORTICULTURAE

Discrete bHLH transcription factors play functionally overlapping roles in pigmentation patterning in flowers of Antirrhinum majus

(2020) Nick W. Albert et al.   NEW PHYTOLOGIST

Advance of the negative regulation of anthocyanin biosynthesis by MYB transcription factors

(2019) Linhuan Chen et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

The B‐Box zinc finger protein MdBBX20 integrates anthocyanin accumulation in response to ultraviolet radiation and low temperature

(2019) Hongcheng Fang et al.   PLANT CELL AND ENVIRONMENT

Grape and wine flavonoid composition in transgenic grapevines with altered expression of flavonoid hydroxylase genes

(2019) S.P. Robinson et al.   AUSTRALIAN JOURNAL OF GRAPE AND WINE RESEARCH

miR828 and miR858 regulate VvMYB114 to promote anthocyanin and flavonol accumulation in grapes

(2019) Varsha Tirumalai et al.   JOURNAL OF EXPERIMENTAL BOTANY

Elevated CO2 delayed the chlorophyll degradation and anthocyanin accumulation in postharvest strawberry fruit

(2019) Dong Li et al.   FOOD CHEMISTRY

Systematic identification of long non‐coding RNA s expressed during light‐induced anthocyanin accumulation in apple fruit

(2019) Tuo Yang et al.   PLANT JOURNAL

Chalcone Isomerase a Key Enzyme for Anthocyanin Biosynthesis in Ophiorrhiza japonica

(2019) Wei Sun et al.   Frontiers in Plant Science

Allele dosage–dependent selection of recessive F3’H allele homozygote altered anthocyanin composition in sweetpotato

(2019) Masaru Tanaka et al.   MOLECULAR BREEDING

ABA and sucrose co-regulate strawberry fruit ripening and show inhibition of glycolysis

(2019) Ya Luo et al.   MOLECULAR GENETICS AND GENOMICS

Transcriptomic Analysis of Red-Fleshed Apples Reveals the Novel Role of MdWRKY11 in Flavonoid and Anthocyanin Biosynthesis

(2018) Nan Wang et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Molecular cloning of flavonoid biosynthetic genes and biochemical characterization of anthocyanin O-methyltransferase of Nemophila menziesii Hook. and Arn.

(2018) Naoko Okitsu et al.   Plant Biotechnology

Identification of DFR as a promoter of anthocyanin accumulation in poinsettia ( Euphorbia pulcherrima , willd. ex Klotzsch) bracts under short-day conditions

(2018) Zhanying Gu et al.   SCIENTIA HORTICULTURAE

The atroviolacea Gene Encodes an R3-MYB Protein Repressing Anthocyanin Synthesis in Tomato Plants

(2018) Sara Colanero et al.   Frontiers in Plant Science

Anthocyanin Biosynthesis and Degradation Mechanisms in Solanaceous Vegetables: A Review

(2018) Ying Liu et al.   Frontiers in Chemistry

Understanding the genetic regulation of anthocyanin biosynthesis in plants – Tools for breeding purple varieties of fruits and vegetables

(2018) Samuel Chaves-Silva et al.   PHYTOCHEMISTRY

Roles of R2R3-MYB transcription factors in transcriptional regulation of anthocyanin biosynthesis in horticultural plants

(2018) Aung Htay Naing et al.   PLANT MOLECULAR BIOLOGY

Overexpression of Rosea1 From Snapdragon Enhances Anthocyanin Accumulation and Abiotic Stress Tolerance in Transgenic Tobacco

(2018) Aung H. Naing et al.   Frontiers in Plant Science

Molecular characterization and functional analysis of chalcone synthase from Syringa oblata Lindl. in the flavonoid biosynthetic pathway

(2017) Yu Wang et al.   GENE

Jasmonate Metabolism and Its Relationship with Abscisic Acid During Strawberry Fruit Development and Ripening

(2017) Adrián Garrido-Bigotes et al.   JOURNAL OF PLANT GROWTH REGULATION

A novel R3 MYB transcriptional repressor associated with the loss of floral pigmentation in Iochroma

(2017) Daniel J. Gates et al.   NEW PHYTOLOGIST

GA-DELLA pathway is involved in regulation of nitrogen deficiency-induced anthocyanin accumulation

(2017) Yongqiang Zhang et al.   PLANT CELL REPORTS

The molecular mechanism underlying anthocyanin metabolism in apple using the MdMYB16 and MdbHLH33 genes

(2017) Haifeng Xu et al.   PLANT MOLECULAR BIOLOGY

The R2R3MYB VvMYBPA1 from grape reprograms the phenylpropanoid pathway in tobacco flowers

(2017) Valentina Passeri et al.   PLANTA

Identification of MicroRNAs and Their Target Genes Related to the Accumulation of Anthocyanins in Litchi chinensis by High-Throughput Sequencing and Degradome Analysis

(2017) Rui Liu et al.   Frontiers in Plant Science

Overexpression of herbaceous peony miR156e-3p improves anthocyanin accumulation in transgenic Arabidopsis thaliana lateral branches

(2017) Daqiu Zhao et al.   3 Biotech

Overexpression of herbaceous peony miR156e-3p improves anthocyanin accumulation in transgenic Arabidopsis thaliana lateral branches

(2017) Daqiu Zhao et al.   3 Biotech

Prokaryotic and Highly-Repetitive WD40 Proteins: A Systematic Study

(2017) Xue-Jia Hu et al.   Scientific Reports

Identification of two novel mutant ANS alleles responsible for inactivation of anthocyanidin synthase and failure of anthocyanin production in onion (Allium cepa L.)

(2016) Eun-Young Kim et al.   EUPHYTICA

Functional identification of apple MdJAZ2 in Arabidopsis with reduced JA-sensitivity and increased stress tolerance

(2016) Xiu-Hong An et al.   PLANT CELL REPORTS

The Arabidopsis UDP-glycosyltransferases UGT79B2 and UGT79B3, contribute to cold, salt and drought stress tolerance via modulating anthocyanin accumulation

(2016) Pan Li et al.   PLANT JOURNAL

Novel insight into the mechanism underlying light-controlled anthocyanin accumulation in eggplant ( Solanum melongena L.)

(2016) Mingmin Jiang et al.   PLANT SCIENCE

Food colorants: Challenges, opportunities and current desires of agro-industries to ensure consumer expectations and regulatory practices

(2016) Natália Martins et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Nonsense Mutation Inside Anthocyanidin Synthase Gene Controls Pigmentation in Yellow Raspberry (Rubus idaeus L.)

(2016) Muhammad Z. Rafique et al.   Frontiers in Plant Science

The expression level of anthocyanidin synthase determines the anthocyanin content of crabapple (Malus sp.) petals

(2015) Jie Zhang et al.   ACTA PHYSIOLOGIAE PLANTARUM

Barley Ant17, encoding flavanone 3-hydroxylase (F3H), is a promising target locus for attaining anthocyanin/proanthocyanidin-free plants without pleiotropic reduction of grain dormancy

(2015) Eiko Himi et al.   GENOME

Methylation mediated by an anthocyanin,O-methyltransferase, is involved in purple flower coloration inPaeonia

(2015) Hui Du et al.   JOURNAL OF EXPERIMENTAL BOTANY

MYBD employed by HY5 increases anthocyanin accumulation via repression ofMYBL2in Arabidopsis

(2015) Nguyen Hoai Nguyen et al.   PLANT JOURNAL

Isolation and Functional Analysis of Chalcone Isomerase Gene from Purple-Fleshed Sweet Potato

(2015) Jinya Guo et al.   PLANT MOLECULAR BIOLOGY REPORTER

The Phenylpropanoid Pathway Is Controlled at Different Branches by a Set of R2R3-MYB C2 Repressors in Grapevine

(2015) Erika Cavallini et al.   PLANT PHYSIOLOGY

Transcriptional control of flavonoid biosynthesis by MYB–bHLH–WDR complexes

(2015) Wenjia Xu et al.   TRENDS IN PLANT SCIENCE

Natural variation for anthocyanin accumulation under high-light and low-temperature stress is attributable to theENHANCER OF AG-4 2(HUA2) locus in combination withPRODUCTION OF ANTHOCYANIN PIGMENT1(PAP1) andPAP2

(2014) Nadine Ilk et al.   NEW PHYTOLOGIST

MdMYB9 and MdMYB11 are Involved in the Regulation of the JA-Induced Biosynthesis of Anthocyanin and Proanthocyanidin in Apples

(2014) Xiu-Hong An et al.   PLANT AND CELL PHYSIOLOGY

A Conserved Network of Transcriptional Activators and Repressors Regulates Anthocyanin Pigmentation in Eudicots

(2014) Nick W. Albert et al.   PLANT CELL

An apple MYB transcription factor, MdMYB3, is involved in regulation of anthocyanin biosynthesis and flower development

(2013) Sornkanok Vimolmangkang et al.   BMC PLANT BIOLOGY

Sucrose Induction of Anthocyanin Biosynthesis Is Mediated by DELLA

(2013) Yi Li et al.   Molecular Plant

Overexpression of microRNA828 reduces anthocyanin accumulation in Arabidopsis

(2013) Fengxi Yang et al.   PLANT CELL TISSUE AND ORGAN CULTURE

Light and the E3 ubiquitin ligase COP1/SPA control the protein stability of the MYB transcription factors PAP1 and PAP2 involved in anthocyanin accumulation in Arabidopsis

(2013) Alexander Maier et al.   PLANT JOURNAL

Enhancement of oxidative and drought tolerance in Arabidopsis by overaccumulation of antioxidant flavonoids

(2013) Ryo Nakabayashi et al.   PLANT JOURNAL

Phenylpropanoid metabolites and expression of key genes involved in anthocyanin biosynthesis in the shaded peel of apple fruit in response to sun exposure

(2013) Fengjuan Feng et al.   PLANT PHYSIOLOGY AND BIOCHEMISTRY

RNAi-Mediated Silencing of the Flavanone 3-Hydroxylase Gene and Its Effect on Flavonoid Biosynthesis in Strawberry Fruit

(2012) Fei Jiang et al.   JOURNAL OF PLANT GROWTH REGULATION

Cytokinins enhance sugar-induced anthocyanin biosynthesis in Arabidopsis

(2012) Prasanta Kumar Das et al.   MOLECULES AND CELLS

The bHLH transcription factor MdbHLH3 promotes anthocyanin accumulation and fruit colouration in response to low temperature in apples

(2012) XING-BIN XIE et al.   PLANT CELL AND ENVIRONMENT

Apple skin patterning is associated with differential expression of MYB10

(2011) Adriana Telias et al.   BMC PLANT BIOLOGY

Enhanced Level of Anthocyanin Leads to Increased Salt Tolerance in Arabidopsis PAP1-D Plants upon Sucrose Treatment

(2011) Jee Eun Oh   Journal of the Korean Society for Applied Biological Chemistry

The Jasmonate-ZIM-Domain Proteins Interact with the WD-Repeat/bHLH/MYB Complexes to Regulate Jasmonate-Mediated Anthocyanin Accumulation and Trichome Initiation inArabidopsis thaliana

(2011) Tiancong Qi et al.   PLANT CELL

Auxin and Ethylene Induce Flavonol Accumulation through Distinct Transcriptional Networks

(2011) D. R. Lewis et al.   PLANT PHYSIOLOGY

Abscisic Acid Plays an Important Role in the Regulation of Strawberry Fruit Ripening

(2011) Hai-Feng Jia et al.   PLANT PHYSIOLOGY

Cloning of FaPAL6 gene from strawberry fruit and characterization of its expression and enzymatic activity in two cultivars with different anthocyanin accumulation

(2011) M.A. Pombo et al.   PLANT SCIENCE

Isolation and characterization of the fragrant cyclamen O-methyltransferase involved in flower coloration

(2011) Yusuke Akita et al.   PLANTA

A WD40-repeat gene from Malus × domestica is a functional homologue of Arabidopsis thaliana TRANSPARENT TESTA GLABRA1

(2010) Julian Brueggemann et al.   PLANT CELL REPORTS

Isolation of WDR and bHLH genes related to flavonoid synthesis in grapevine (Vitis vinifera L.)

(2010) J. T. Matus et al.   PLANT MOLECULAR BIOLOGY

Genome-Wide Classification and Evolutionary Analysis of the bHLH Family of Transcription Factors in Arabidopsis, Poplar, Rice, Moss, and Algae

(2010) L. Carretero-Paulet et al.   PLANT PHYSIOLOGY

Ethylene Suppression of Sugar-Induced Anthocyanin Pigmentation in Arabidopsis

(2010) S.-W. Jeong et al.   PLANT PHYSIOLOGY

Ectopic Expression of Apple F3'H Genes Contributes to Anthocyanin Accumulation in the Arabidopsis tt7 Mutant Grown Under Nitrogen Stress

(2010) Y. Han et al.   PLANT PHYSIOLOGY

Hormonal modulation of photomorphogenesis-controlled anthocyanin accumulation in tomato (Solanum lycopersicum L. cv Micro-Tom) hypocotyls: Physiological and genetic studies

(2010) Rogério Falleiros Carvalho et al.   PLANT SCIENCE

Molecular mechanism for jasmonate-induction of anthocyanin accumulation in Arabidopsis

(2009) X. Shan et al.   JOURNAL OF EXPERIMENTAL BOTANY

A Novel Cation-Dependent O-Methyltransferase Involved in Anthocyanin Methylation in Grapevine

(2009) P. Hugueney et al.   PLANT PHYSIOLOGY

A MYB transcription factor regulates anthocyanin biosynthesis in mangosteen (Garcinia mangostana L.) fruit during ripening

(2009) Yossapol Palapol et al.   PLANTA

Distinct extremely abundant siRNAs associated with cosuppression in petunia

(2009) E. De Paoli et al.   RNA

Gibberellins, jasmonate and abscisic acid modulate the sucrose-induced expression of anthocyanin biosynthetic genes inArabidopsis

(2008) Elena Loreti et al.   NEW PHYTOLOGIST

Regulation of the anthocyanin biosynthetic pathway by the TTG1/bHLH/Myb transcriptional complex in Arabidopsis seedlings

(2008) Antonio Gonzalez et al.   PLANT JOURNAL