Targeting ferroptosis in gastric cancer: Strategies and opportunities
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Targeting ferroptosis in gastric cancer: Strategies and opportunities
Authors
Keywords
-
Journal
IMMUNOLOGICAL REVIEWS
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2023-10-31
DOI
10.1111/imr.13280
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Loss of cancer-associated fibroblast-derived exosomal DACT3-AS1 promotes malignant transformation and ferroptosis-mediated oxaliplatin resistance in gastric cancer
- (2023) Xianlin Qu et al. DRUG RESISTANCE UPDATES
- Hereditary Diffuse Gastric Cancer
- (2023) Lyvianne Decourtye-Espiard et al. GASTROENTEROLOGY
- Polyphyllin B Suppresses Gastric Tumor Growth by Modulating Iron Metabolism and Inducing Ferroptosis
- (2023) Can Hu et al. International Journal of Biological Sciences
- E-cadherin is a biomarker for ferroptosis sensitivity in diffuse gastric cancer
- (2023) Alexander M. Minikes et al. ONCOGENE
- Glutathione metabolism rewiring protects renal tubule cells against cisplatin-induced apoptosis and ferroptosis
- (2023) Xing-Qiang Dong et al. REDOX REPORT
- GPX4: The hub of lipid oxidation, ferroptosis, disease and treatment
- (2023) Yi Liu et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- 287-LB: Thiazolidinedione Ameliorates Lipotoxicity-Induced Pancreatic ß-Cell Ferroptosis Partly via ACSL4
- (2023) MEI ZHANG et al. DIABETES
- Isoorientin reverses lung cancer drug resistance by promoting ferroptosis via the SIRT6/Nrf2/GPX4 signaling pathway
- (2023) Senling Feng et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Glutathione peroxidase 2 knockdown suppresses gastric cancer progression and metastasis via regulation of kynurenine metabolism
- (2023) Handong Xu et al. ONCOGENE
- Dual inhibition of MYC and SLC39A10 by a novel natural product STAT3 inhibitor derived from Chaetomium globosum suppresses tumor growth and metastasis in gastric cancer
- (2023) Xiaoqing Guan et al. PHARMACOLOGICAL RESEARCH
- HNF4A-BAP31-VDAC1 axis synchronously regulates cell proliferation and ferroptosis in gastric cancer
- (2023) Qingqing Zhou et al. Cell Death & Disease
- Platycodin-D exerts its anti-cancer effect by promoting c-Myc protein ubiquitination and degradation in gastric cancer
- (2023) Qianqian Xu et al. Frontiers in Pharmacology
- Tubastatin A potently inhibits GPX4 activity to potentiate cancer radiotherapy through boosting ferroptosis
- (2023) Shan Liu et al. Redox Biology
- MGST1 Expression Is Associated with Poor Prognosis, Enhancing the Wnt/β-Catenin Pathway via Regulating AKT and Inhibiting Ferroptosis in Gastric Cancer
- (2023) Yaxian Li et al. ACS Omega
- Baicalin enhances the efficacy of 5-Fluorouracil in gastric cancer by promoting ROS-mediated ferroptosis
- (2023) Jingwen Yuan et al. BIOMEDICINE & PHARMACOTHERAPY
- Fighting drug-resistant lung cancer by induction of NAD(P)H:quinone oxidoreductase 1 (NQO1)-mediated ferroptosis
- (2023) Jie Yu et al. DRUG RESISTANCE UPDATES
- Activation pathways that drive CD4 + T cells to break tolerance in autoimmune diseases
- (2022) Sai Harsha Krovi et al. IMMUNOLOGICAL REVIEWS
- The lncRNA BDNF-AS/WDR5/FBXW7 axis mediates ferroptosis in gastric cancer peritoneal metastasis by regulating VDAC3 ubiquitination
- (2022) Guoquan Huang et al. International Journal of Biological Sciences
- Regulation of Ferroptosis by Amino Acid Metabolism in Cancer
- (2022) Jian Yang et al. International Journal of Biological Sciences
- Ferroptosis in cancer therapy: a novel approach to reversing drug resistance
- (2022) Chen Zhang et al. Molecular Cancer
- Ferritinophagy-Mediated Ferroptosis and Activation of Keap1/Nrf2/HO-1 Pathway Were Conducive to EMT Inhibition of Gastric Cancer Cells in Action of 2,2 ′ -Di-pyridineketone Hydrazone Dithiocarbamate Butyric Acid Ester
- (2022) Deng Guan et al. Oxidative Medicine and Cellular Longevity
- The paradigm of drug resistance in cancer: an epigenetic perspective
- (2022) Swagata Adhikari et al. BIOSCIENCE REPORTS
- Wnt/beta-catenin signaling confers ferroptosis resistance by targeting GPX4 in gastric cancer
- (2022) Yue Wang et al. CELL DEATH AND DIFFERENTIATION
- Catching a killer: Mechanisms of programmed cell death and immune activation in Amyotrophic Lateral Sclerosis
- (2022) Dylan V. Neel et al. IMMUNOLOGICAL REVIEWS
- Ferroptosis at the intersection of lipid metabolism and cellular signaling
- (2022) Deguang Liang et al. MOLECULAR CELL
- Activation of SSAT1/ALOX15 Axis Aggravates Cerebral Ischemia/Reperfusion Injury via Triggering Neuronal Ferroptosis
- (2022) Jie Zhao et al. NEUROSCIENCE
- Expression of ferroptosis-related gene correlates with immune microenvironment and predicts prognosis in gastric cancer
- (2022) Siyuan Song et al. Scientific Reports
- Ferroptosis and Tumor Drug Resistance: Current Status and Major Challenges
- (2022) Zhenyu Nie et al. Frontiers in Pharmacology
- Inhibition of STAT3-ferroptosis negative regulatory axis suppresses tumor growth and alleviates chemoresistance in gastric cancer
- (2022) Shumin Ouyang et al. Redox Biology
- Hypoxia-induced HIF-1α/lncRNA-PMAN inhibits ferroptosis by promoting the cytoplasmic translocation of ELAVL1 in peritoneal dissemination from gastric cancer
- (2022) Zaihuan Lin et al. Redox Biology
- Ferroptosis turns 10: Emerging mechanisms, physiological functions, and therapeutic applications
- (2022) Brent R. Stockwell CELL
- A non-canonical vitamin K cycle is a potent ferroptosis suppressor
- (2022) Eikan Mishima et al. NATURE
- The molecular and metabolic landscape of iron and ferroptosis in cardiovascular disease
- (2022) Xuexian Fang et al. Nature Reviews Cardiology
- Ferroptosis and its Role in Gastric Cancer
- (2022) Renjun Gu et al. Frontiers in Cell and Developmental Biology
- ACSL4 is essential for radiation-induced intestinal injury by initiating ferroptosis
- (2022) Qian Ji et al. Cell Death Discovery
- Abrogation of ARF6 in promoting erastin-induced ferroptosis and mitigating capecitabine resistance in gastric cancer cells
- (2022) Donghua Geng et al. Journal of Gastrointestinal Oncology
- Iron metabolism, ferroptosis, and lncRNA in cancer: knowns and unknowns
- (2022) Lei Qu et al. Journal of Zhejiang University-SCIENCE B
- System Xc−/GSH/GPX4 axis: An important antioxidant system for the ferroptosis in drug-resistant solid tumor therapy
- (2022) Feng-Jiao Li et al. Frontiers in Pharmacology
- Prognostic Model and Immune Infiltration of Ferroptosis Subcluster-Related Modular Genes in Gastric Cancer
- (2022) Huachu Deng et al. Journal of Oncology
- High co‐expression of SLC7A11 and GPX4 as a predictor of platinum resistance and poor prognosis in patients with epithelial ovarian cancer
- (2022) Xiaodong Wu et al. BJOG-AN INTERNATIONAL JOURNAL OF OBSTETRICS AND GYNAECOLOGY
- CST1 inhibits ferroptosis and promotes gastric cancer metastasis by regulating GPX4 protein stability via OTUB1
- (2022) Dongbao Li et al. ONCOGENE
- PNO1 inhibits autophagy-mediated ferroptosis by GSH metabolic reprogramming in hepatocellular carcinoma
- (2022) Xiaomeng Hu et al. Cell Death & Disease
- Ferroptosis inhibition by deferiprone, attenuates myelin damage and promotes neuroprotection in demyelinated optic nerve
- (2022) Atefeh Rayatpour et al. Scientific Reports
- Increased ATF2 expression predicts poor prognosis and inhibits sorafenib-induced ferroptosis in gastric cancer
- (2022) Xin Xu et al. Redox Biology
- ACSL3 and ACSL4, Distinct Roles in Ferroptosis and Cancers
- (2022) Yufei Yang et al. Cancers
- Recent progress in ferroptosis: inducers and inhibitors
- (2022) Yunxi Du et al. Cell Death Discovery
- The deubiquitinase OTUD1 enhances iron transport and potentiates host antitumor immunity
- (2021) Jia Song et al. EMBO REPORTS
- Ferroptosis: mechanisms, biology and role in disease
- (2021) Xuejun Jiang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Release mechanisms of major DAMPs
- (2021) Atsushi Murao et al. APOPTOSIS
- Global cancer statistics 2020: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries
- (2021) Hyuna Sung et al. CA-A CANCER JOURNAL FOR CLINICIANS
- System Xc−: a key regulatory target of ferroptosis in cancer
- (2021) Man-ru Liu et al. INVESTIGATIONAL NEW DRUGS
- Broadening horizons: the role of ferroptosis in cancer
- (2021) Xin Chen et al. Nature Reviews Clinical Oncology
- Construction and Validation of a Ferroptosis-Related Prognostic Model for Gastric Cancer
- (2021) Xiaotao Jiang et al. Journal of Oncology
- Lipid Metabolism and Ferroptosis
- (2021) Ji-Yoon Lee et al. Biology-Basel
- DHODH-mediated ferroptosis defence is a targetable vulnerability in cancer
- (2021) Chao Mao et al. NATURE
- MYCN mediates TFRC-dependent ferroptosis and reveals vulnerabilities in neuroblastoma
- (2021) Yuxiong Lu et al. Cell Death & Disease
- GSTZ1 sensitizes hepatocellular carcinoma cells to sorafenib-induced ferroptosis via inhibition of NRF2/GPX4 axis
- (2021) Qiujie Wang et al. Cell Death & Disease
- Identification of ferroptosis as a novel mechanism for antitumor activity of natural product derivative a2 in gastric cancer
- (2021) Ying Liu et al. Acta Pharmaceutica Sinica B
- Induction of ferroptosis by ATF3 elevation alleviates cisplatin resistance in gastric cancer by restraining Nrf2/Keap1/xCT signaling
- (2021) Dazhi Fu et al. CELLULAR & MOLECULAR BIOLOGY LETTERS
- Signaling pathways and defense mechanisms of ferroptosis
- (2021) Jiao Liu et al. FEBS Journal
- Cancer‐associated fibroblasts: Key players in shaping the tumor immune microenvironment
- (2021) Mélanie Desbois et al. IMMUNOLOGICAL REVIEWS
- Identification and validation of a novel ferroptosis-related gene model for predicting the prognosis of gastric cancer patients
- (2021) Gang Liu et al. PLoS One
- Multifaceted mechanisms mediating cystine starvation-induced ferroptosis
- (2021) Zhennan Shi et al. Nature Communications
- Levobupivacaine Induces Ferroptosis by miR-489-3p/SLC7A11 Signaling in Gastric Cancer
- (2021) Shun-Hong Mao et al. Frontiers in Pharmacology
- Lipid Metabolism in Ferroptosis
- (2021) Zhi Lin et al. Advanced Biology
- SIRT6 silencing overcomes resistance to sorafenib by promoting ferroptosis in gastric cancer
- (2021) Shunv Cai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Advances in clinical immunotherapy for gastric cancer
- (2021) Kexin Li et al. BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER
- Diverse cytoprotective actions of vitamin E isoforms- role as peroxyl radical scavengers and complementary functions with selenoproteins
- (2021) Yoshiro Saito FREE RADICAL BIOLOGY AND MEDICINE
- Diving into the mechanism of action of tumor immunotherapies with intravital imaging*
- (2021) Philippe Bousso IMMUNOLOGICAL REVIEWS
- Comprehensive Analysis of Ferroptosis-Related Markers for the Clinical and Biological Value in Gastric Cancer
- (2021) Yanfei Shao et al. Oxidative Medicine and Cellular Longevity
- Research progress on SLC7A11 in the regulation of cystine/cysteine metabolism in tumors (Review)
- (2021) Xiang Tang et al. Oncology Letters
- Development and Validation of a Novel Ferroptosis-Related Gene Signature for Predicting Prognosis and the Immune Microenvironment in Gastric Cancer
- (2021) Feng Wang et al. Biomed Research International
- Propofol induces ferroptosis and inhibits malignant phenotypes of gastric cancer cells by regulating miR-125b-5p/STAT3 axis
- (2021) Yi-Ping Liu et al. World Journal of Gastrointestinal Oncology
- DMT1 Inhibitors Kill Cancer Stem Cells by Blocking Lysosomal Iron Translocation
- (2020) Andreea L. Turcu et al. CHEMISTRY-A EUROPEAN JOURNAL
- CAF secreted miR-522 suppresses ferroptosis and promotes acquired chemo-resistance in gastric cancer
- (2020) Haiyang Zhang et al. Molecular Cancer
- Hepatic Transferrin Plays a Role in Systemic Iron Homeostasis and Liver Ferroptosis
- (2020) Yingying Yu et al. BLOOD
- Noncoding RNAs in gastric cancer: implications for drug resistance
- (2020) Ling Wei et al. Molecular Cancer
- Selective covalent targeting of GPX4 using masked nitrile-oxide electrophiles
- (2020) John K. Eaton et al. Nature Chemical Biology
- Cysteine Depletion, a Key Action to Challenge Cancer Cells to Ferroptotic Cell Death
- (2020) Boutaina Daher et al. Frontiers in Oncology
- Artesunate synergizes with sorafenib to induce ferroptosis in hepatocellular carcinoma
- (2020) Zhong-jie Li et al. ACTA PHARMACOLOGICA SINICA
- Stearoyl-CoA desaturase 1 (SCD1) facilitates the growth and anti-ferroptosis of gastric cancer cells and predicts poor prognosis of gastric cancer
- (2020) Chao Wang et al. Aging-US
- Actinidia chinensis Planch prevents proliferation and migration of gastric cancer associated with apoptosis, ferroptosis activation and mesenchymal phenotype suppression
- (2020) Zhuowei Gao et al. BIOMEDICINE & PHARMACOTHERAPY
- Human umbilical cord blood–derived MSCs exosome attenuate myocardial injury by inhibiting ferroptosis in acute myocardial infarction mice
- (2020) Yufang Song et al. CELL BIOLOGY AND TOXICOLOGY
- Broad Spectrum Deubiquitinase Inhibition Induces Both Apoptosis and Ferroptosis in Cancer Cells
- (2020) Li Yang et al. Frontiers in Oncology
- NEDD4L-mediated LTF protein degradation limits ferroptosis
- (2020) Yuan Wang et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ferroptosis mediated by the interaction between Mfn2 and IREα promotes arsenic-induced nonalcoholic steatohepatitis
- (2020) Sen Wei et al. ENVIRONMENTAL RESEARCH
- Gastric cancer
- (2020) Elizabeth C Smyth et al. LANCET
- Cystine transporter SLC7A11/xCT in cancer: ferroptosis, nutrient dependency, and cancer therapy
- (2020) Pranavi Koppula et al. Protein & Cell
- Iron Metabolism in Ferroptosis
- (2020) Xin Chen et al. Frontiers in Cell and Developmental Biology
- Ferroptosis: molecular mechanisms and health implications
- (2020) Daolin Tang et al. CELL RESEARCH
- Ferroptosis involves in renal tubular cell death in diabetic nephropathy
- (2020) Yue Wang et al. EUROPEAN JOURNAL OF PHARMACOLOGY
- Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
- (2020) Bo Yan et al. MOLECULAR CELL
- Ferroptotic damage promotes pancreatic tumorigenesis through a TMEM173/STING-dependent DNA sensor pathway
- (2020) Enyong Dai et al. Nature Communications
- The lipogenic regulator SREBF2 induces Transferrin in circulating melanoma cells and suppresses ferroptosis
- (2020) Xin Hong et al. Cancer Discovery
- NRF2 plays a critical role in mitigating lipid peroxidation and ferroptosis
- (2019) Matthew Dodson et al. Redox Biology
- GPX4 at the Crossroads of Lipid Homeostasis and Ferroptosis
- (2019) Giovanni C. Forcina et al. PROTEOMICS
- Hemin-induced platelet activation and ferroptosis is mediated through ROS-driven proteasomal activity and inflammasome activation: Protection by Melatonin
- (2019) Somanathapura K. NaveenKumar et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Targeting Ferroptosis to Iron Out Cancer
- (2019) Behrouz Hassannia et al. CANCER CELL
- Artemisinin compounds sensitize cancer cells to ferroptosis by regulating iron homeostasis
- (2019) Guo-Qing Chen et al. CELL DEATH AND DIFFERENTIATION
- CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
- (2019) Weimin Wang et al. NATURE
- The Non-Essential Amino Acid Cysteine Becomes Essential for Tumor Proliferation and Survival
- (2019) Joseph A. Combs et al. Cancers
- Genetic Ablation of the Cystine Transporter xCT in PDAC Cells Inhibits mTORC1, Growth, Survival, and Tumor Formation via Nutrient and Oxidative Stresses
- (2019) Boutaina Daher et al. CANCER RESEARCH
- The modification of ferroptosis and abnormal lipometabolism through overexpression and knockdown of potential prognostic biomarker perilipin2 in gastric carcinoma
- (2019) Xiaoying Sun et al. Gastric Cancer
- Inhibition of tumor propellant glutathione peroxidase 4 induces ferroptosis in cancer cells and enhances anticancer effect of cisplatin
- (2019) Xuefei Zhang et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Dihydroartemisinin-induced unfolded protein response feedback attenuates ferroptosis via PERK/ATF4/HSPA5 pathway in glioma cells
- (2019) Yibing Chen et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Recent Progress in Ferroptosis Inducers for Cancer Therapy
- (2019) Chen Liang et al. ADVANCED MATERIALS
- RNA-binding protein ZFP36/TTP protects against ferroptosis by regulating autophagy signaling pathway in hepatic stellate cells
- (2019) Zili Zhang et al. Autophagy
- FSP1 is a glutathione-independent ferroptosis suppressor
- (2019) Sebastian Doll et al. NATURE
- The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
- (2019) Kirill Bersuker et al. NATURE
- The chemical basis of ferroptosis
- (2019) Marcus Conrad et al. Nature Chemical Biology
- Insight into the mechanism of ferroptosis inhibition by ferrostatin-1
- (2019) Giovanni Miotto et al. Redox Biology
- GTP Cyclohydrolase 1/Tetrahydrobiopterin Counteract Ferroptosis through Lipid Remodeling
- (2019) Vanessa A. N. Kraft et al. ACS Central Science
- Suppression of the SLC7A11/glutathione axis causes synthetic lethality in KRAS-mutant lung adenocarcinoma
- (2019) Kewen Hu et al. JOURNAL OF CLINICAL INVESTIGATION
- Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
- (2018) Irina Ingold et al. CELL
- The glutamine transporter ASCT2 (SLC1A5) promotes tumor growth independently of the amino acid transporter LAT1 (SLC7A5)
- (2018) Yann Cormerais et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glutathione metabolism in cancer progression and treatment resistance
- (2018) Ankita Bansal et al. JOURNAL OF CELL BIOLOGY
- Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
- (2018) Behrouz Hassannia et al. JOURNAL OF CLINICAL INVESTIGATION
- FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation
- (2018) Michael M. Gaschler et al. Nature Chemical Biology
- The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma
- (2018) Heike Miess et al. ONCOGENE
- Cysteine Metabolism in Neuronal Redox Homeostasis
- (2018) Bindu D. Paul et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- The ferroptosis inducer erastin irreversibly inhibits system xc− and synergizes with cisplatin to increase cisplatin’s cytotoxicity in cancer cells
- (2018) Mami Sato et al. Scientific Reports
- Oxytosis/Ferroptosis—(Re-) Emerging Roles for Oxidative Stress-Dependent Non-apoptotic Cell Death in Diseases of the Central Nervous System
- (2018) Jan Lewerenz et al. Frontiers in Neuroscience
- Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis
- (2018) Ron Shah et al. ACS Central Science
- Role of GPX4 in ferroptosis and its pharmacological implication
- (2018) Tobias M. Seibt et al. FREE RADICAL BIOLOGY AND MEDICINE
- Vitamin E hydroquinone is an endogenous regulator of ferroptosis via redox control of 15-lipoxygenase
- (2018) Andrew Hinman et al. PLoS One
- Nrf2 inhibition reverses resistance to GPX4 inhibitor-induced ferroptosis in head and neck cancer
- (2018) Daiha Shin et al. FREE RADICAL BIOLOGY AND MEDICINE
- Cystinuria: genetic aspects, mouse models, and a new approach to therapy
- (2018) Amrik Sahota et al. Urolithiasis
- Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-Analysis
- (2017) James K.Y. Hooi et al. GASTROENTEROLOGY
- The glutamate/cystine antiporter SLC7A11/xCT enhances cancer cell dependency on glucose by exporting glutamate
- (2017) Pranavi Koppula et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
- ROS in Cancer: The Burning Question
- (2017) Iok In Christine Chio et al. TRENDS IN MOLECULAR MEDICINE
- Ferroptosis Inhibition: Mechanisms and Opportunities
- (2017) Jose Pedro Friedmann Angeli et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- An ultrasensitive fluorogenic probe for revealing the role of glutathione in chemotherapy resistance
- (2017) Yuejing Jiang et al. Chemical Science
- Mitochondrial complex I inhibition triggers a mitophagy-dependent ROS increase leading to necroptosis and ferroptosis in melanoma cells
- (2017) Farhan Basit et al. Cell Death & Disease
- Cysteine Dioxygenase 1 Mediates Erastin-Induced Ferroptosis in Human Gastric Cancer Cells
- (2017) Shihui Hao et al. NEOPLASIA
- Behavioural Effects of Using Sulfasalazine to Inhibit Glutamate Released by Cancer Cells: A Novel target for Cancer-Induced Depression
- (2017) Mina G. Nashed et al. Scientific Reports
- Five-Membered Ring Peroxide Selectively Initiates Ferroptosis in Cancer Cells
- (2016) Rachel P. Abrams et al. ACS Chemical Biology
- A simple isotopic labeling method to study cysteine oxidation in Alzheimer’s disease: oxidized cysteine-selective dimethylation (OxcysDML)
- (2016) Liqing Gu et al. ANALYTICAL AND BIOANALYTICAL CHEMISTRY
- Autophagy promotes ferroptosis by degradation of ferritin
- (2016) Wen Hou et al. Autophagy
- Identification of ACSL4 as a biomarker and contributor of ferroptosis
- (2016) Hua Yuan et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Genetic Disruption of the Multifunctional CD98/LAT1 Complex Demonstrates the Key Role of Essential Amino Acid Transport in the Control of mTORC1 and Tumor Growth
- (2016) Y. Cormerais et al. CANCER RESEARCH
- Mechanisms of ferroptosis
- (2016) Jennifer Yinuo Cao et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis
- (2016) Xiaofang Sun et al. HEPATOLOGY
- Glutathione peroxidase 4: a new player in neurodegeneration?
- (2016) B R Cardoso et al. MOLECULAR PSYCHIATRY
- Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
- (2016) Valerian E Kagan et al. Nature Chemical Biology
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- Ferroptosis: Death by Lipid Peroxidation
- (2016) Wan Seok Yang et al. TRENDS IN CELL BIOLOGY
- Ferroptosis is induced following siramesine and lapatinib treatment of breast cancer cells
- (2016) S Ma et al. Cell Death & Disease
- Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
- (2015) Scott J. Dixon et al. ACS Chemical Biology
- Mammalian lipoxygenases and their biological relevance
- (2015) Hartmut Kuhn et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- The 5-Lipoxygenase Inhibitor Zileuton Confers Neuroprotection against Glutamate Oxidative Damage by Inhibiting Ferroptosis
- (2015) Yang Liu et al. BIOLOGICAL & PHARMACEUTICAL BULLETIN
- Incorporation of metabolically stable ketones into a small molecule probe to increase potency and water solubility
- (2015) Marie-Helene Larraufie et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Elucidating Compound Mechanism of Action by Network Perturbation Analysis
- (2015) Jung Hoon Woo et al. CELL
- Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression
- (2015) Zhaoyong Li et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- Mechanistic and regulatory aspects of intestinal iron absorption
- (2014) Sukru Gulec et al. AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
- (2014) Scott J Dixon et al. eLife
- Control of apoptosis by the BCL-2 protein family: implications for physiology and therapy
- (2013) Peter E. Czabotar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The Cystine/Glutamate Antiporter System xc− in Health and Disease: From Molecular Mechanisms to Novel Therapeutic Opportunities
- (2012) Jan Lewerenz et al. ANTIOXIDANTS & REDOX SIGNALING
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Lactotransferrin acts as a tumor suppressor in nasopharyngeal carcinoma by repressing AKT through multiple mechanisms
- (2012) M Deng et al. ONCOGENE
- The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond
- (2011) Marcus Conrad et al. AMINO ACIDS
- Development of small-molecule probes that selectively kill cells induced to express mutant RAS
- (2011) Michel Weïwer et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Eukaryotic DNA polymerases require an iron-sulfur cluster for the formation of active complexes
- (2011) Daili J A Netz et al. Nature Chemical Biology
- Two to Tango: Regulation of Mammalian Iron Metabolism
- (2010) Matthias W. Hentze et al. CELL
- Biochemical and physiological function of stearoyl-CoA desaturase
- (2008) Chad M. Paton et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Regulation of glutathione synthesis
- (2008) Shelly C. Lu MOLECULAR ASPECTS OF MEDICINE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreDiscover Peeref hubs
Discuss science. Find collaborators. Network.
Join a conversation