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Title
The chemical basis of ferroptosis
Authors
Keywords
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Journal
Nature Chemical Biology
Volume 15, Issue 12, Pages 1137-1147
Publisher
Springer Science and Business Media LLC
Online
2019-11-19
DOI
10.1038/s41589-019-0408-1
References
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Note: Only part of the references are listed.- H-Atom Abstraction vs. Addition: Accounting for the Diverse Product Distribution in the Autoxidation of Cholesterol & its Esters
- (2019) Zosia A. M. Zielinski et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ferroptosis as a target for protection against cardiomyopathy
- (2019) Xuexian Fang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Squalene accumulation in cholesterol auxotrophic lymphomas prevents oxidative cell death
- (2019) Javier Garcia-Bermudez et al. NATURE
- Threshold protective effect of deuterated polyunsaturated fatty acids on peroxidation of lipid bilayers
- (2019) Alexander M. Firsov et al. FEBS Journal
- Ischemia-induced ACSL4 activation contributes to ferroptosis-mediated tissue injury in intestinal ischemia/reperfusion
- (2019) Yang Li et al. CELL DEATH AND DIFFERENTIATION
- The deubiquitylase OTUB1 mediates ferroptosis via stabilization of SLC7A11
- (2019) Tong Liu et al. CANCER RESEARCH
- The Coming Decade of Cell Death Research: Five Riddles
- (2019) Douglas R. Green CELL
- CD8+ T cells regulate tumour ferroptosis during cancer immunotherapy
- (2019) Weimin Wang et al. NATURE
- ALOX12 is required for p53-mediated tumour suppression through a distinct ferroptosis pathway
- (2019) Bo Chu et al. NATURE CELL BIOLOGY
- Cystine–glutamate antiporter xCT deficiency suppresses tumor growth while preserving antitumor immunity
- (2019) Michael D. Arensman et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- FSP1 is a glutathione-independent ferroptosis suppressor
- (2019) Sebastian Doll et al. NATURE
- The CoQ oxidoreductase FSP1 acts parallel to GPX4 to inhibit ferroptosis
- (2019) Kirill Bersuker et al. NATURE
- Determination of the Subcellular Localization and Mechanism of Action of Ferrostatins in Suppressing Ferroptosis
- (2018) Michael M. Gaschler et al. ACS Chemical Biology
- Emerging Strategies of Cancer Therapy Based on Ferroptosis
- (2018) Zheyu Shen et al. ADVANCED MATERIALS
- Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress
- (2018) Jennifer Tsoi et al. CANCER CELL
- Selenium Utilization by GPX4 Is Required to Prevent Hydroperoxide-Induced Ferroptosis
- (2018) Irina Ingold et al. CELL
- miR-137 regulates ferroptosis by targeting glutamine transporter SLC1A5 in melanoma
- (2018) Meiying Luo et al. CELL DEATH AND DIFFERENTIATION
- Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018
- (2018) Lorenzo Galluzzi et al. CELL DEATH AND DIFFERENTIATION
- Regulation of lipid peroxidation and ferroptosis in diverse species
- (2018) Marcus Conrad et al. GENES & DEVELOPMENT
- Nano-targeted induction of dual ferroptotic mechanisms eradicates high-risk neuroblastoma
- (2018) Behrouz Hassannia et al. JOURNAL OF CLINICAL INVESTIGATION
- Quantitative Profiling of Protein Carbonylations in Ferroptosis by an Aniline-Derived Probe
- (2018) Ying Chen et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- The Catalytic Reaction of Nitroxides with Peroxyl Radicals and Its Relevance to Their Cytoprotective Properties
- (2018) Markus Griesser et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- FINO2 initiates ferroptosis through GPX4 inactivation and iron oxidation
- (2018) Michael M. Gaschler et al. Nature Chemical Biology
- The glutathione redox system is essential to prevent ferroptosis caused by impaired lipid metabolism in clear cell renal cell carcinoma
- (2018) Heike Miess et al. ONCOGENE
- Inhibition of hydrocarbon autoxidation by nitroxide-catalyzed cross-dismutation of hydroperoxyl and alkylperoxyl radicals
- (2018) Kareem A. Harrison et al. Chemical Science
- Resolving the Role of Lipoxygenases in the Initiation and Execution of Ferroptosis
- (2018) Ron Shah et al. ACS Central Science
- Selenium-Encoded Isotopic Signature Targeted Profiling
- (2018) Jinjun Gao et al. ACS Central Science
- Recent Insights on Hydrogen Atom Transfer in the Inhibition of Hydrocarbon Autoxidation
- (2018) Jia-Fei Poon et al. ACCOUNTS OF CHEMICAL RESEARCH
- Ferroptosis and necroinflammation, a yet poorly explored link
- (2018) Bettina Proneth et al. CELL DEATH AND DIFFERENTIATION
- Pseudomonas aeruginosa utilizes host polyunsaturated phosphatidylethanolamines to trigger theft-ferroptosis in bronchial epithelium
- (2018) Haider H. Dar et al. JOURNAL OF CLINICAL INVESTIGATION
- BAP1 links metabolic regulation of ferroptosis to tumour suppression
- (2018) Yilei Zhang et al. NATURE CELL BIOLOGY
- Role of Mitochondria in Ferroptosis
- (2018) Minghui Gao et al. MOLECULAR CELL
- Phenoxazine: A Privileged Scaffold for Radical-Trapping Antioxidants
- (2017) Luke A. Farmer et al. JOURNAL OF ORGANIC CHEMISTRY
- Tau-mediated iron export prevents ferroptotic damage after ischemic stroke
- (2017) Q-z Tuo et al. MOLECULAR PSYCHIATRY
- NFS1 undergoes positive selection in lung tumours and protects cells from ferroptosis
- (2017) Samantha W. Alvarez et al. NATURE
- Drug-tolerant persister cancer cells are vulnerable to GPX4 inhibition
- (2017) Matthew J. Hangauer et al. NATURE
- Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway
- (2017) Vasanthi S. Viswanathan et al. NATURE
- Iron addiction: a novel therapeutic target in ovarian cancer
- (2017) D Basuli et al. ONCOGENE
- On the Mechanism of Cytoprotection by Ferrostatin-1 and Liproxstatin-1 and the Role of Lipid Peroxidation in Ferroptotic Cell Death
- (2017) Omkar Zilka et al. ACS Central Science
- Autophagy promotes ferroptosis by degradation of ferritin
- (2016) Wen Hou et al. Autophagy
- Ferroptosis is an autophagic cell death process
- (2016) Minghui Gao et al. CELL RESEARCH
- Oxidized arachidonic and adrenic PEs navigate cells to ferroptosis
- (2016) Valerian E Kagan et al. Nature Chemical Biology
- ACSL4 dictates ferroptosis sensitivity by shaping cellular lipid composition
- (2016) Sebastian Doll et al. Nature Chemical Biology
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- Systemic depletion of L-cyst(e)ine with cyst(e)inase increases reactive oxygen species and suppresses tumor growth
- (2016) Shira L Cramer et al. NATURE MEDICINE
- Ultrasmall nanoparticles induce ferroptosis in nutrient-deprived cancer cells and suppress tumour growth
- (2016) Sung Eun Kim et al. Nature Nanotechnology
- Regulated necrosis: disease relevance and therapeutic opportunities
- (2016) Marcus Conrad et al. NATURE REVIEWS DRUG DISCOVERY
- Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
- (2016) Wan Seok Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A Mitochondrial-Targeted Nitroxide Is a Potent Inhibitor of Ferroptosis
- (2016) Tanja Krainz et al. ACS Central Science
- Human Haploid Cell Genetics Reveals Roles for Lipid Metabolism Genes in Nonapoptotic Cell Death
- (2015) Scott J. Dixon et al. ACS Chemical Biology
- Cyclooxygenase-Dependent Tumor Growth through Evasion of Immunity
- (2015) Santiago Zelenay et al. CELL
- Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
- (2015) Xiaofang Sun et al. HEPATOLOGY
- Ablation of the Ferroptosis Inhibitor Glutathione Peroxidase 4 in Neurons Results in Rapid Motor Neuron Degeneration and Paralysis
- (2015) Liuji Chen et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Bilayer Deformation, Pores, and Micellation Induced by Oxidized Lipids
- (2015) Phansiri Boonnoy et al. Journal of Physical Chemistry Letters
- Glutaminolysis and Transferrin Regulate Ferroptosis
- (2015) Minghui Gao et al. MOLECULAR CELL
- Ferroptosis is Involved in Acetaminophen Induced Cell Death
- (2015) Tamás Lőrincz et al. PATHOLOGY & ONCOLOGY RESEARCH
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Advances in Radical-Trapping Antioxidant Chemistry in the 21st Century: A Kinetics and Mechanisms Perspective
- (2014) Keith U. Ingold et al. CHEMICAL REVIEWS
- Competition H(D) Kinetic Isotope Effects in the Autoxidation of Hydrocarbons
- (2014) Hubert Muchalski et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ferrostatins Inhibit Oxidative Lipid Damage and Cell Death in Diverse Disease Models
- (2014) Rachid Skouta et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
- (2014) Edward T. Chouchani et al. NATURE
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Synchronized renal tubular cell death involves ferroptosis
- (2014) Andreas Linkermann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Oxidatively Truncated Phospholipids Are Required Agents of Tumor Necrosis Factor α (TNFα)-induced Apoptosis
- (2012) Calivarathan Latchoumycandane et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The oxidative stress-inducible cystine/glutamate antiporter, system x c − : cystine supplier and beyond
- (2011) Marcus Conrad et al. AMINO ACIDS
- Development of small-molecule probes that selectively kill cells induced to express mutant RAS
- (2011) Michel Weïwer et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- Lipoxygenase and Leukotriene Pathways: Biochemistry, Biology, and Roles in Disease
- (2011) Jesper Z. Haeggström et al. CHEMICAL REVIEWS
- Free Radical Lipid Peroxidation: Mechanisms and Analysis
- (2011) Huiyong Yin et al. CHEMICAL REVIEWS
- Oxysterols from Free Radical Chain Oxidation of 7-Dehydrocholesterol: Product and Mechanistic Studies
- (2010) Libin Xu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Short Form Glutathione Peroxidase 4 Is the Essential Isoform Required for Survival and Somatic Mitochondrial Functions
- (2009) Hanyu Liang et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
- (2008) Alexander Seiler et al. Cell Metabolism
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