An ultrasensitive fluorogenic probe for revealing the role of glutathione in chemotherapy resistance

In This Issue/Research Watch/News-in-Brief/News from the IASLC Tobacco Control Committee

(2017)   Journal of Thoracic Oncology

Identification of the metabolic alterations associated with the multidrug resistant phenotype in cancer and their intercellular transfer mediated by extracellular vesicles

(2017) Vanessa Lopes-Rodrigues et al.   Scientific Reports

Naphthalimide Scaffold Provides Versatile Platform for Selective Thiol Sensing and Protein Labeling

(2016) Pengcheng Zhou et al.   ACS Chemical Biology

Click and chemically triggered declick reactions through reversible amine and thiol coupling via a conjugate acceptor

(2016) Katharine L. Diehl et al.   Nature Chemistry

Rational design of reversible fluorescent probes for live-cell imaging and quantification of fast glutathione dynamics

(2016) Keitaro Umezawa et al.   Nature Chemistry

Decreased glutathione biosynthesis contributes to EGFR T790M-driven erlotinib resistance in non-small cell lung cancer

(2016) Hongde Li et al.   Cell Discovery

Resistance to cancer chemotherapy: failure in drug response from ADME to P-gp

(2015) Khalid O Alfarouk et al.   Cancer Cell International

Theoretical and Experimental Investigation of Thermodynamics and Kinetics of Thiol-Michael Addition Reactions: A Case Study of Reversible Fluorescent Probes for Glutathione Imaging in Single Cells

(2015) Jianwei Chen et al.   ORGANIC LETTERS

The glutathione synthesis inhibitor buthionine sulfoximine synergistically enhanced melphalan activity against preclinical models of multiple myeloma

(2014) A Tagde et al.   Blood Cancer Journal

Analysis of GSH and GSSG after derivatization with N-ethylmaleimide

(2013) Daniela Giustarini et al.   Nature Protocols

Role of Glutathione in Cancer Progression and Chemoresistance

(2013) Nicola Traverso et al.   Oxidative Medicine and Cellular Longevity

Reduced Glutathione: A Radioprotector or a Modulator of DNA-Repair Activity?

(2013) Anupam Chatterjee   Nutrients

Glutathione levels in human tumors

(2012) Michael P. Gamcsik et al.   BIOMARKERS

Changes in intracellular redox status influence multidrug resistance in gastric adenocarcinoma cells

(2012) DE-JUN TAI et al.   Experimental and Therapeutic Medicine

The role of glutathione in brain tumor drug resistance

(2011) Donald S. Backos et al.   BIOCHEMICAL PHARMACOLOGY

Molecular mechanisms of cisplatin resistance

(2011) L Galluzzi et al.   ONCOGENE

Tumor pH and Its Measurement

(2010) X. Zhang et al.   JOURNAL OF NUCLEAR MEDICINE