Dihydroartemisinin-induced unfolded protein response feedback attenuates ferroptosis via PERK/ATF4/HSPA5 pathway in glioma cells
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Title
Dihydroartemisinin-induced unfolded protein response feedback attenuates ferroptosis via PERK/ATF4/HSPA5 pathway in glioma cells
Authors
Keywords
Dihydroartemisinin, Ferroptosis, GPX4, Endoplasmic reticulum stress, HSPA5, Glioma
Journal
JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
Volume 38, Issue 1, Pages -
Publisher
Springer Science and Business Media LLC
Online
2019-09-13
DOI
10.1186/s13046-019-1413-7
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Note: Only part of the references are listed.- EIF2A promotes cell survival during paclitaxel treatment in vitro and in vivo
- (2019) Lin Chen et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
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- (2018) S. Wang et al. ONCOGENE
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- (2018) Sabine Hombach-Klonisch et al. PHARMACOLOGY & THERAPEUTICS
- CQ synergistically sensitizes human colorectal cancer cells to SN-38/CPT-11 through lysosomal and mitochondrial apoptotic pathway via p53-ROS cross-talk
- (2017) Pinjia Chen et al. FREE RADICAL BIOLOGY AND MEDICINE
- HSPA5 Gene encoding Hsp70 chaperone BiP in the endoplasmic reticulum
- (2017) Jie Wang et al. GENE
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- (2017) Caitlin W. Brown et al. JOURNAL OF CELL BIOLOGY
- From ancient herb to modern drug: Artemisia annua and artemisinin for cancer therapy
- (2017) Thomas Efferth SEMINARS IN CANCER BIOLOGY
- Surviving Stress: Modulation of ATF4-Mediated Stress Responses in Normal and Malignant Cells
- (2017) Inge M.N. Wortel et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Nrf2-Keap1 pathway promotes cell proliferation and diminishes ferroptosis
- (2017) Z Fan et al. Oncogenesis
- Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells
- (2016) Renyu Lin et al. CANCER LETTERS
- Ferroptosis: process and function
- (2016) Y Xie et al. CELL DEATH AND DIFFERENTIATION
- Contribution of reactive oxygen species to ovarian cancer cell growth arrest and killing by the anti-malarial drug artesunate
- (2016) Anna L. Greenshields et al. MOLECULAR CARCINOGENESIS
- Global survey of cell death mechanisms reveals metabolic regulation of ferroptosis
- (2016) Kenichi Shimada et al. Nature Chemical Biology
- Regulated necrosis: disease relevance and therapeutic opportunities
- (2016) Marcus Conrad et al. NATURE REVIEWS DRUG DISCOVERY
- Activation ofSAT1engages polyamine metabolism with p53-mediated ferroptotic responses
- (2016) Yang Ou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Inhibition of endoplasmic reticulum (ER) stress sensors sensitizes cancer stem-like cells to ER stress-mediated apoptosis
- (2016) Asaha Fujimoto et al. Oncotarget
- Temozolomide toxicity operates in a xCT/SLC7a11 dependent manner and is fostered by ferroptosis
- (2016) Tina Sehm et al. Oncotarget
- Dihydroartemisinin induces apoptosis preferentially via a Bim-mediated intrinsic pathway in hepatocarcinoma cells
- (2015) Guiqi Qin et al. APOPTOSIS
- HSPB1 as a novel regulator of ferroptotic cancer cell death
- (2015) X Sun et al. ONCOGENE
- Artemisinin derivatives induce iron-dependent cell death (ferroptosis) in tumor cells
- (2015) Edna Ooko et al. PHYTOMEDICINE
- Dihydroartemisinin and its derivative induce apoptosis in acute myeloid leukemia through Noxa-mediated pathway requiring iron and endoperoxide moiety
- (2015) Xuan Zhao et al. Oncotarget
- Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
- (2015) Min-Young Kwon et al. Oncotarget
- Dihydroartemisinin Inhibits Glucose Uptake and Cooperates with Glycolysis Inhibitor to Induce Apoptosis in Non-Small Cell Lung Carcinoma Cells
- (2015) Yan-jun Mi et al. PLoS One
- Regulation of Ferroptotic Cancer Cell Death by GPX4
- (2014) Wan Seok Yang et al. CELL
- Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress–induced cell death during the unfolded protein response
- (2014) Nobuhiko Hiramatsu et al. MOLECULAR BIOLOGY OF THE CELL
- Pharmacological inhibition of cystine–glutamate exchange induces endoplasmic reticulum stress and ferroptosis
- (2014) Scott J Dixon et al. eLife
- Glioblastoma and Other Malignant Gliomas
- (2013) Antonio Omuro JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION
- Qinghaosu (artemisinin): Chemistry and pharmacology
- (2012) Ying Li ACTA PHARMACOLOGICA SINICA
- Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
- (2012) Scott J. Dixon et al. CELL
- Lipid Peroxidation Product 4-Hydroxy-trans-2-nonenal Causes Endothelial Activation by Inducing Endoplasmic Reticulum Stress
- (2012) Elena Vladykovskaya et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Current State of Our Knowledge on Brain Tumor Epidemiology
- (2011) Quinn T. Ostrom et al. Current Neurology and Neuroscience Reports
- The anti-cancer activity of dihydroartemisinin is associated with induction of iron-dependent endoplasmic reticulum stress in colorectal carcinoma HCT116 cells
- (2010) Jin-Jian Lu et al. INVESTIGATIONAL NEW DRUGS
- Dihydroartemisinin Induces Apoptosis by a Bak-Dependent Intrinsic Pathway
- (2010) R. Handrick et al. MOLECULAR CANCER THERAPEUTICS
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