Chemogenetic modulation of astrocytes and microglia: State‐of‐the‐art and implications in neuroscience
Published 2023 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Chemogenetic modulation of astrocytes and microglia: State‐of‐the‐art and implications in neuroscience
Authors
Keywords
-
Journal
GLIA
Volume -, Issue -, Pages -
Publisher
Wiley
Online
2023-05-24
DOI
10.1002/glia.24390
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Microglia modulate blood flow, neurovascular coupling, and hypoperfusion via purinergic actions
- (2022) Eszter Császár et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Microglial lactate metabolism as a potential therapeutic target for Alzheimer’s disease
- (2022) Yingjun Zhao et al. Molecular Neurodegeneration
- Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses
- (2022) Jessica L. Bolton et al. Cell Reports
- Ethanol Induces Secretion of Proinflammatory Extracellular Vesicles That Inhibit Adult Hippocampal Neurogenesis Through G9a/GLP-Epigenetic Signaling
- (2022) Jian Zou et al. Frontiers in Immunology
- Adolescent ethanol drinking promotes hyperalgesia, neuroinflammation and serotonergic deficits in mice that persist into adulthood
- (2022) Kanza M. Khan et al. BRAIN BEHAVIOR AND IMMUNITY
- Directed evolution of adeno-associated virus for efficient gene delivery to microglia
- (2022) Rui Lin et al. NATURE METHODS
- Chimeric GPCRs mimic distinct signaling pathways and modulate microglia responses
- (2022) Rouven Schulz et al. Nature Communications
- Sciatic nerve block downregulates the BDNF pathway to alleviate the neonatal incision-induced exaggeration of incisional pain via decreasing microglial activation
- (2022) Xu Ding et al. BRAIN BEHAVIOR AND IMMUNITY
- Ventrolateral periaqueductal gray astrocytes regulate nociceptive sensation and emotional motivation in diabetic neuropathic pain
- (2022) Lan Yang et al. JOURNAL OF NEUROSCIENCE
- Advances in Optogenetics Applications for Central Nervous System Injuries
- (2022) Yuanming Geng et al. JOURNAL OF NEUROTRAUMA
- Glucocorticoid regulation of lactate release from spinal astrocytes contributes to the induction of spinal LTP of C-fiber-evoked field potentials and the development of mechanical allodynia
- (2022) Ruizhen Huang et al. NEUROPHARMACOLOGY
- Chemogenetic and Optogenetic Manipulations of Microglia in Chronic Pain
- (2022) Sebastian Parusel et al. Neuroscience Bulletin
- Cocaine’s cerebrovascular vasoconstriction is associated with astrocytic Ca2+ increase in mice
- (2022) Yanzuo Liu et al. Communications Biology
- Basolateral amygdala astrocytes modulate diabetic neuropathic pain and may be a potential therapeutic target for koumine
- (2022) Jing‐Shan Lu et al. BRITISH JOURNAL OF PHARMACOLOGY
- Molecular and spatial signatures of mouse brain aging at single-cell resolution
- (2022) William E. Allen et al. CELL
- Microglial store-operated calcium signaling in health and in Alzheimer’s disease
- (2021) James G McLarnon Current Alzheimer Research
- Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons
- (2021) Anna M. Klawonn et al. IMMUNITY
- Role of Astrocytes in Major Neuropsychiatric Disorders
- (2021) Xiaolu Zhang et al. NEUROCHEMICAL RESEARCH
- Microglial MT1 activation inhibits LPS‐induced neuroinflammation via regulation of metabolic reprogramming
- (2021) Chao Gu et al. AGING CELL
- Chemogenetic manipulation of astrocytic signaling in the basolateral amygdala reduces binge‐like alcohol consumption in male mice
- (2021) Kala N. Nwachukwu et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Evidence in primates supporting the use of chemogenetics for the treatment of human refractory neuropsychiatric disorders
- (2021) Patrick H. Roseboom et al. MOLECULAR THERAPY
- Microglia reprogram metabolic profiles for phenotype and function changes in central nervous system
- (2021) Sheng Yang et al. NEUROBIOLOGY OF DISEASE
- Cortical astrocytes independently regulate sleep depth and duration via separate GPCR pathways
- (2021) Trisha V Vaidyanathan et al. eLife
- Microglia react to partner loss in a sex- and brain site-specific manner in prairie voles
- (2021) Tobias T. Pohl et al. BRAIN BEHAVIOR AND IMMUNITY
- GFAP positivity in neurons following traumatic brain injuries
- (2021) Johann Zwirner et al. INTERNATIONAL JOURNAL OF LEGAL MEDICINE
- In Vivo Neocortical [K]o Modulation by Targeted Stimulation of Astrocytes
- (2021) Azin EbrahimAmini et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Capillary-associated microglia regulate vascular structure and function through PANX1-P2RY12 coupling in mice
- (2021) Kanchan Bisht et al. Nature Communications
- Side-by-side comparison of the effects of Gq- and Gi-DREADD-mediated astrocyte modulation on intracellular calcium dynamics and synaptic plasticity in the hippocampal CA1
- (2021) Yana Van Den Herrewegen et al. Molecular Brain
- Level of hM4D(Gi) DREADD Expression Determines Inhibitory and Neurotoxic Effects in the Hippocampus
- (2021) Marie-Gabrielle Goossens et al. eNeuro
- Chemogenetic stimulation of the G i pathway in astrocytes suppresses neuroinflammation
- (2021) Jae‐Hong Kim et al. Pharmacology Research & Perspectives
- Impaired glucose tolerance and indeterminate glycemia in cystic fibrosis
- (2021) Nader Kasim et al. Journal of Clinical and Translational Endocrinology
- Chemogenetics a Robust Approach to Pharmacology and Gene Therapy
- (2020) O. Keifer et al. BIOCHEMICAL PHARMACOLOGY
- Emerging technologies to study glial cells
- (2020) Hélène Hirbec et al. GLIA
- Microglial depletion and repopulation in brain slice culture normalizes sensitized proinflammatory signaling
- (2020) Leon G. Coleman et al. Journal of Neuroinflammation
- Improved tools to study astrocytes
- (2020) Xinzhu Yu et al. NATURE REVIEWS NEUROSCIENCE
- Astrocytes and Microglia: In Sickness and in Health
- (2020) Ilia D. Vainchtein et al. TRENDS IN NEUROSCIENCES
- Bi-Directional Communication Between Neurons and Astrocytes Modulates Spinal Motor Circuits
- (2020) Matthew J. Broadhead et al. Frontiers in Cellular Neuroscience
- Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance
- (2020) Yuki Oe et al. Nature Communications
- Differential Expression of the Metabotropic P2Y Receptor Family in the Cortex Following Status Epilepticus and Neuroprotection via P2Y1 Antagonism in Mice
- (2020) Mariana Alves et al. Frontiers in Pharmacology
- GFAP (Glial Fibrillary Acidic Protein)-Positive Progenitor Cells Contribute to the Development of Vascular Smooth Muscle Cells and Endothelial Cells—Brief Report
- (2020) Islam Osman et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Activation of Astrocytes in the Dorsomedial Striatum Facilitates Transition from Habitual to Goal-Directed Reward-Seeking Behavior
- (2020) Seungwoo Kang et al. BIOLOGICAL PSYCHIATRY
- Chronic hM3Dq signaling in microglia ameliorates neuroinflammation in male mice
- (2020) William Binning et al. BRAIN BEHAVIOR AND IMMUNITY
- P2Y6 receptor inhibition aggravates ischemic brain injury by reducing microglial phagocytosis
- (2020) Ruo‐Xue Wen et al. CNS Neuroscience & Therapeutics
- In vivo electrophysiological validation of DREADD‐based modulation of pallidal neurons in the non‐human primate
- (2020) Marc Deffains et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- The role of P2Y12 receptor inhibition in ischemic stroke on microglia, platelets and vascular smooth muscle cells
- (2020) Fengyang Li et al. JOURNAL OF THROMBOSIS AND THROMBOLYSIS
- Effect of chemogenetic actuator drugs on prefrontal cortex-dependent working memory in nonhuman primates
- (2020) Nicholas A. Upright et al. NEUROPSYCHOPHARMACOLOGY
- Cortical astrocytes regulate ethanol consumption and intoxication in mice
- (2020) E. K. Erickson et al. NEUROPSYCHOPHARMACOLOGY
- G-Protein-Coupled Receptors in Astrocyte–Neuron Communication
- (2020) Paulo Kofuji et al. NEUROSCIENCE
- Metabolic Reprograming of Microglia in the Regulation of the Innate Inflammatory Response
- (2020) Clotilde Lauro et al. Frontiers in Immunology
- No Longer Underappreciated: The Emerging Concept of Astrocyte Heterogeneity in Neuroscience
- (2020) Francisco Pestana et al. Brain Sciences
- Chemical biology of noncanonical G protein–coupled receptor signaling: Toward advanced therapeutics
- (2020) Maria M. Shchepinova et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Dietary fat exacerbates postprandial hypothalamic inflammation involving glial fibrillary acidic protein-positive cells and microglia in male mice
- (2020) Céline Cansell et al. GLIA
- Priming of microglia with IFN ‐γ impairs adult hippocampal neurogenesis and leads to depression‐like behaviors and cognitive defects
- (2020) Jinqiang Zhang et al. GLIA
- Astrocyte Signaling Gates Long-Term Depression at Corticostriatal Synapses of the Direct Pathway
- (2020) Anna Cavaccini et al. JOURNAL OF NEUROSCIENCE
- Deschloroclozapine, a potent and selective chemogenetic actuator enables rapid neuronal and behavioral modulations in mice and monkeys
- (2020) Yuji Nagai et al. NATURE NEUROSCIENCE
- Astrocytes contribute to remote memory formation by modulating hippocampal–cortical communication during learning
- (2020) Adi Kol et al. NATURE NEUROSCIENCE
- Drug Resistance in Epilepsy: Clinical Impact, Potential Mechanisms, and New Innovative Treatment Options
- (2020) Wolfgang Löscher et al. PHARMACOLOGICAL REVIEWS
- d-Serine as the gatekeeper of NMDA receptor activity: implications for the pharmacologic management of anxiety disorders
- (2020) Herman Wolosker et al. Translational Psychiatry
- Chemogenetic Regulation of CX3CR1-Expressing Microglia Using Gi-DREADD Exerts Sex-Dependent Anti-Allodynic Effects in Mouse Models of Neuropathic Pain
- (2020) Fumihiro Saika et al. Frontiers in Pharmacology
- Cerebral blood flow decrease as an early pathological mechanism in Alzheimer's disease
- (2020) Nils Korte et al. ACTA NEUROPATHOLOGICA
- Deletion of muscarinic acetylcholine receptor 3 in microglia impacts brain ischemic injury
- (2020) Amanda Costa et al. BRAIN BEHAVIOR AND IMMUNITY
- The effects of microglia‐ and astrocyte‐derived factors on neurogenesis in health and disease
- (2020) Tasuku Araki et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Regulation of blood–brain barrier integrity by microglia in health and disease: A therapeutic opportunity
- (2020) Patrick T Ronaldson et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable
- (2020) Xinzhu Yu et al. NEURON
- Sensory satellite glial Gq-GPCR activation alleviates inflammatory pain via peripheral adenosine 1 receptor activation
- (2020) Alison Xiaoqiao Xie et al. Scientific Reports
- Local Translation in Perisynaptic Astrocytic Processes Is Specific and Changes after Fear Conditioning
- (2020) Noémie Mazaré et al. Cell Reports
- Tools and Approaches for Studying Microglia In vivo
- (2020) Elisa Eme-Scolan et al. Frontiers in Immunology
- Multiplexed chemogenetics in astrocytes and motoneurons restore blood–spinal cord barrier in ALS
- (2020) Najwa Ouali Alami et al. Life Science Alliance
- Involvement of microglia in disturbed fear memory regulation: Possible microglial contribution to the pathophysiology of posttraumatic stress disorder
- (2020) Shingo Enomoto et al. NEUROCHEMISTRY INTERNATIONAL
- Microglial Calcium Waves During the Hyperacute Phase of Ischemic Stroke
- (2020) Lei Liu et al. STROKE
- The Potential Role of Pro-Inflammatory and Anti-Inflammatory Cytokines in Epilepsy Pathogenesis
- (2020) Ali N. Kamali et al. Endocrine Metabolic & Immune Disorders-Drug Targets
- Short-term cerebral blood flow variability in major depressive disorder
- (2020) Stefan Duschek et al. JOURNAL OF AFFECTIVE DISORDERS
- Effects of Methamphetamine Self-Administration and Extinction on Astrocyte Structure and Function in the Nucleus Accumbens Core
- (2019) B.M. Siemsen et al. NEUROSCIENCE
- Therapeutic AAV Gene Transfer to the Nervous System: A Clinical Reality
- (2019) Eloise Hudry et al. NEURON
- Adeno-associated virus vector as a platform for gene therapy delivery
- (2019) Dan Wang et al. NATURE REVIEWS DRUG DISCOVERY
- Mechanism underlying β2-AR agonist-mediated phenotypic conversion of LPS-activated microglial cells
- (2019) Monika Sharma et al. JOURNAL OF NEUROIMMUNOLOGY
- The Astrocytic cAMP Pathway in Health and Disease
- (2019) Zhiwen Zhou et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Gi/o protein-coupled receptors inhibit neurons but activate astrocytes and stimulate gliotransmission
- (2019) Caitlin A. Durkee et al. GLIA
- Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue
- (2019) Jun Nagai et al. CELL
- Ultrastructural localization of DREADD s in monkeys
- (2019) Adriana Galvan et al. EUROPEAN JOURNAL OF NEUROSCIENCE
- Microglia-mediated neuroinflammation in neurodegenerative diseases
- (2019) Charannya Sozheesvari Subhramanyam et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Transient, Consequential Increases in Extracellular Potassium Ions Accompany Channelrhodopsin2 Excitation
- (2019) J. Christopher Octeau et al. Cell Reports
- The Chemogenetic Receptor Ligand Clozapine N-Oxide Induces in vivo Neuroreceptor Occupancy and Reduces Striatal Glutamate Levels
- (2019) Simone Bærentzen et al. Frontiers in Neuroscience
- Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury
- (2019) Suvi Pöyhönen et al. Frontiers in Physiology
- Olanzapine: A potent agonist at the hM4D(Gi) DREADD amenable to clinical translation of chemogenetics
- (2019) Mikail Weston et al. Science Advances
- Designer receptor technology for the treatment of epilepsy
- (2019) Andreas Lieb et al. EBioMedicine
- Hot topic in optogenetics: new implications of in vivo tissue heating
- (2019) Daniel F. Cardozo Pinto et al. NATURE NEUROSCIENCE
- Activation of Astrocytic μ-Opioid Receptor Causes Conditioned Place Preference
- (2019) Min-Ho Nam et al. Cell Reports
- Pharmacological targeting of β 2 ‐adrenoceptors is neuroprotective in the LPS inflammatory rat model of Parkinson's disease
- (2019) Eoin O'Neill et al. BRITISH JOURNAL OF PHARMACOLOGY
- Microglial Pro-Inflammatory and Anti-Inflammatory Phenotypes Are Modulated by Translocator Protein Activation
- (2019) Pozzo et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Increasing cerebral blood flow improves cognition into late stages in Alzheimer’s disease mice
- (2019) Oliver Bracko et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Optogenetic and chemogenetic therapies for epilepsy
- (2019) Matthew C. Walker et al. NEUROPHARMACOLOGY
- Targeting microglia with lentivirus and AAV: Recent advances and remaining challenges
- (2019) Margaret E. Maes et al. NEUROSCIENCE LETTERS
- Fractalkine Modulates Microglia Metabolism in Brain Ischemia
- (2019) Clotilde Lauro et al. Frontiers in Cellular Neuroscience
- Long‐term chemogenetic suppression of spontaneous seizures in a mouse model for temporal lobe epilepsy
- (2019) Jana Desloovere et al. EPILEPSIA
- Regulation of food intake by astrocytes in the brainstem dorsal vagal complex
- (2019) Alastair J. MacDonald et al. GLIA
- Increased plasma levels of mitochondrial DNA and pro-inflammatory cytokines in patients with progressive multiple sclerosis
- (2019) Milena Nasi et al. JOURNAL OF NEUROIMMUNOLOGY
- Astrocytic Activation Generates De Novo Neuronal Potentiation and Memory Enhancement
- (2018) Adar Adamsky et al. CELL
- DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats
- (2018) Peter M. Grace et al. EXPERIMENTAL NEUROLOGY
- Widespread transduction of astrocytes and neurons in the mouse central nervous system after systemic delivery of a self-complementary AAV-PHP.B vector
- (2018) Melvin Y. Rincon et al. GENE THERAPY
- Gliotransmission: Beyond Black-and-White
- (2018) Iaroslav Savtchouk et al. JOURNAL OF NEUROSCIENCE
- Multiple Lines of Evidence Indicate That Gliotransmission Does Not Occur under Physiological Conditions
- (2018) Todd A. Fiacco et al. JOURNAL OF NEUROSCIENCE
- Re-evaluating microglia expression profiles using RiboTag and cell isolation strategies
- (2018) Zhana Haimon et al. NATURE IMMUNOLOGY
- Blood–brain barrier breakdown in Alzheimer disease and other neurodegenerative disorders
- (2018) Melanie D. Sweeney et al. Nature Reviews Neurology
- Astrocytes, neurons, synapses: a tripartite view on cortical circuit development
- (2018) Isabella Farhy-Tselnicker et al. Neural Development
- Chemogenetic Manipulation of Dorsal Hippocampal Astrocytes Protects Against the Development of Stress-enhanced Fear Learning
- (2018) Meghan E. Jones et al. NEUROSCIENCE
- Astroglial cAMP signalling in space and time
- (2018) Anemari Horvat et al. NEUROSCIENCE LETTERS
- Chemogenetic Tools for Causal Cellular and Neuronal Biology
- (2018) Deniz Atasoy et al. PHYSIOLOGICAL REVIEWS
- Physiology of Astroglia
- (2018) Alexei Verkhratsky et al. PHYSIOLOGICAL REVIEWS
- Functional Roles of Astrocyte Calcium Elevations: From Synapses to Behavior
- (2018) Sónia Guerra-Gomes et al. Frontiers in Cellular Neuroscience
- The Aging Astrocyte Transcriptome from Multiple Regions of the Mouse Brain
- (2018) Matthew M. Boisvert et al. Cell Reports
- Astrocytic Atrophy Following Status Epilepticus Parallels Reduced Ca2+ Activity and Impaired Synaptic Plasticity in the Rat Hippocampus
- (2018) Alex Plata et al. Frontiers in Molecular Neuroscience
- Noradrenergic Transmission at Alpha1-Adrenergic Receptors in the Ventral Periaqueductal Gray Modulates Arousal
- (2018) Kirsten A. Porter-Stransky et al. BIOLOGICAL PSYCHIATRY
- Neuroinflammatory mechanisms in amyotrophic lateral sclerosis pathogenesis
- (2018) Jason R. Thonhoff et al. CURRENT OPINION IN NEUROLOGY
- Reducing Astrocyte Calcium Signaling In Vivo Alters Striatal Microcircuits and Causes Repetitive Behavior
- (2018) Xinzhu Yu et al. NEURON
- Importance of GPCR-Mediated Microglial Activation in Alzheimer’s Disease
- (2018) Md. Ezazul Haque et al. Frontiers in Cellular Neuroscience
- The DREADD agonist clozapine N-oxide (CNO) is reverse-metabolized to clozapine and produces clozapine-like interoceptive stimulus effects in rats and mice
- (2018) Daniel F. Manvich et al. Scientific Reports
- Dual action of L-Lactate on the activity of NR2B-containing NMDA receptors: from potentiation to neuroprotection
- (2018) P. Jourdain et al. Scientific Reports
- Modulation of Microglial Activation by Adenosine A2a Receptor in Animal Models of Perinatal Brain Injury
- (2018) Marina Colella et al. Frontiers in Neurology
- Astrocyte-neuron lactate shuttle sensitizes nociceptive transmission in the spinal cord
- (2018) Keisuke Miyamoto et al. GLIA
- Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes
- (2018) Timothy R. Hammond et al. IMMUNITY
- Astrocytes and microglia: Models and tools
- (2018) Kevin A. Guttenplan et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Lactate Deficit in an Alzheimer Disease Mouse Model: The Relationship With Neuronal Damage
- (2018) Mao Zhang et al. JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY
- Conditional Knockout of mGluR5 from Astrocytes during Epilepsy Development Impairs High-Frequency Glutamate Uptake
- (2018) Anthony D. Umpierre et al. JOURNAL OF NEUROSCIENCE
- Microglia and the Purinergic Signaling System
- (2018) Stefano Calovi et al. NEUROSCIENCE
- Does obesity cause type 2 diabetes mellitus (T2DM)? Or is it the opposite?
- (2018) John I. Malone et al. PEDIATRIC DIABETES
- Metabotropic Glutamate Receptors in Glial Cells: A New Potential Target for Neuroprotection?
- (2018) Simona Federica Spampinato et al. Frontiers in Molecular Neuroscience
- Hypothalamic Microglial Activation in Obesity: A Mini-Review
- (2018) Natália F. Mendes et al. Frontiers in Neuroscience
- Incretin hormones regulate microglia oxidative stress, survival and expression of trophic factors
- (2017) Lindsay Joy Spielman et al. EUROPEAN JOURNAL OF CELL BIOLOGY
- Microglia P2Y6 receptor is related to Parkinson’s disease through neuroinflammatory process
- (2017) Xiaodong Yang et al. Journal of Neuroinflammation
- Applications of optogenetic and chemogenetic methods to seizure circuits: Where to go next?
- (2017) Patrick A. Forcelli JOURNAL OF NEUROSCIENCE RESEARCH
- Synapse-specific astrocyte gating of amygdala-related behavior
- (2017) Mario Martin-Fernandez et al. NATURE NEUROSCIENCE
- Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence
- (2017) Hua Chai et al. NEURON
- The role of neuroimmune signaling in alcoholism
- (2017) Fulton T. Crews et al. NEUROPHARMACOLOGY
- Single-Dose Gene-Replacement Therapy for Spinal Muscular Atrophy
- (2017) Jerry R. Mendell et al. NEW ENGLAND JOURNAL OF MEDICINE
- Chemogenetics revealed: DREADD occupancy and activation via converted clozapine
- (2017) Juan L. Gomez et al. SCIENCE
- Three-dimensional Ca2+imaging advances understanding of astrocyte biology
- (2017) Erika Bindocci et al. SCIENCE
- Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y 1 Receptor Downregulation
- (2017) Youichi Shinozaki et al. Cell Reports
- Astrocytes release prostaglandin E2 to modify respiratory network activity
- (2017) David Forsberg et al. eLife
- Motor Areas Show Altered Dendritic Structure in an Amyotrophic Lateral Sclerosis Mouse Model
- (2017) Matthew J. Fogarty et al. Frontiers in Neuroscience
- AAV-Mediated Astrocyte-Specific Gene Expression under Human ALDH1L1 Promoter in Mouse Thalamus
- (2017) Wuhyun Koh et al. Experimental Neurobiology
- Reactive gliosis in the pathogenesis of CNS diseases
- (2016) Milos Pekny et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Adrenergic stimulation of single rat astrocytes results in distinct temporal changes in intracellular Ca2+ and cAMP-dependent PKA responses
- (2016) Anemari Horvat et al. CELL CALCIUM
- Inflammatory Process in Alzheimer's and Parkinson's Diseases: Central Role of Cytokines
- (2016) Qamre Alam et al. CURRENT PHARMACEUTICAL DESIGN
- Astrocytes as secretory cells of the central nervous system: idiosyncrasies of vesicular secretion
- (2016) A. Verkhratsky et al. EMBO JOURNAL
- Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain
- (2016) Sun Kwang Kim et al. JOURNAL OF CLINICAL INVESTIGATION
- Gene therapy for the CNS using AAVs: The impact of systemic delivery by AAV9
- (2016) Joana Saraiva et al. JOURNAL OF CONTROLLED RELEASE
- Sinomenine activates astrocytic dopamine D2 receptors and alleviates neuroinflammatory injury via the CRYAB/STAT3 pathway after ischemic stroke in mice
- (2016) Jing Qiu et al. Journal of Neuroinflammation
- Cholinergic Neurons in the Basal Forebrain Promote Wakefulness by Actions on Neighboring Non-Cholinergic Neurons: An Opto-Dialysis Study
- (2016) J. C. Zant et al. JOURNAL OF NEUROSCIENCE
- Resolving Behavioral Output via Chemogenetic Designer Receptors Exclusively Activated by Designer Drugs
- (2016) C. Joseph Burnett et al. JOURNAL OF NEUROSCIENCE
- Dysfunctional Calcium and Glutamate Signaling in Striatal Astrocytes from Huntington's Disease Model Mice
- (2016) R. Jiang et al. JOURNAL OF NEUROSCIENCE
- Increased pregenual anterior cingulate glucose and lactate concentrations in major depressive disorder
- (2016) J Ernst et al. MOLECULAR PSYCHIATRY
- In-depth neuropharmacokinetic analysis of antipsychotics based on a novel approach to estimate unbound target-site concentration in CNS regions: link to spatial receptor occupancy
- (2016) I Loryan et al. MOLECULAR PSYCHIATRY
- Astrocyte calcium signaling: the third wave
- (2016) Narges Bazargani et al. NATURE NEUROSCIENCE
- DREADDs for Neuroscientists
- (2016) Bryan L. Roth NEURON
- Microglia Priming with Aging and Stress
- (2016) Anzela Niraula et al. NEUROPSYCHOPHARMACOLOGY
- Astrocytic β2-adrenergic receptors mediate hippocampal long-term memory consolidation
- (2016) Virginia Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation
- (2016) Peter M. Grace et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- New tools for studying microglia in the mouse and human CNS
- (2016) Mariko L. Bennett et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Activity-dependent switch of GABAergic inhibition into glutamatergic excitation in astrocyte-neuron networks
- (2016) Gertrudis Perea et al. eLife
- Direct modulation of GFAP-expressing glia in the arcuate nucleus bi-directionally regulates feeding
- (2016) Naiyan Chen et al. eLife
- Transcriptional activity of novel ALDH1L1 promoters in the rat brain following AAV vector-mediated gene transfer
- (2016) Janitha M Mudannayake et al. Molecular Therapy-Methods & Clinical Development
- Microglia-specific targeting by novel capsid-modified AAV6 vectors
- (2016) Awilda M Rosario et al. Molecular Therapy-Methods & Clinical Development
- Optogenetic and Chemogenetic Approaches for Studying Astrocytes and Gliotransmitters
- (2016) Juwon Bang et al. Experimental Neurobiology
- The First Structure–Activity Relationship Studies for Designer Receptors Exclusively Activated by Designer Drugs
- (2015) Xin Chen et al. ACS Chemical Neuroscience
- Gq-DREADD Selectively Initiates Glial Glutamate Release and Inhibits Cue-induced Cocaine Seeking
- (2015) Michael D. Scofield et al. BIOLOGICAL PSYCHIATRY
- Metabolic gene expression changes in astrocytes in Multiple Sclerosis cerebral cortex are indicative of immune-mediated signaling
- (2015) T. Zeis et al. BRAIN BEHAVIOR AND IMMUNITY
- Microglial M1/M2 polarization and metabolic states
- (2015) Ruben Orihuela et al. BRITISH JOURNAL OF PHARMACOLOGY
- Extracellular acidosis impairs P2Y receptor-mediated Ca2+ signalling and migration of microglia
- (2015) Antonia Langfelder et al. CELL CALCIUM
- Enhanced astroglial Ca2+signaling increases excitatory synaptic strength in the epileptic brain
- (2015) Carla Álvarez-Ferradas et al. GLIA
- The inhibitory neurotransmitter GABA evokes long-lasting Ca2+oscillations in cortical astrocytes
- (2015) Letizia Mariotti et al. GLIA
- Making Sense of Optogenetics
- (2015) Akash Guru et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Cerebral Hypoperfusion: A New Pathophysiologic Concept in Multiple Sclerosis?
- (2015) Miguel D'haeseleer et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- P2Y6 Receptor-Mediated Microglial Phagocytosis in Radiation-Induced Brain Injury
- (2015) Yongteng Xu et al. MOLECULAR NEUROBIOLOGY
- A New DREADD Facilitates the Multiplexed Chemogenetic Interrogation of Behavior
- (2015) Eyal Vardy et al. NEURON
- Microglial priming and enhanced reactivity to secondary insult in aging, and traumatic CNS injury, and neurodegenerative disease
- (2015) Diana M. Norden et al. NEUROPHARMACOLOGY
- Decrease of gene expression of astrocytic 5-HT2B receptors parallels development of depressive phenotype in a mouse model of Parkinson’s disease
- (2015) Xique Zhang et al. Frontiers in Cellular Neuroscience
- Molecular approaches for manipulating astrocytic signaling in vivo
- (2015) Alison X. Xie et al. Frontiers in Cellular Neuroscience
- A New Outlook on Mental Illnesses: Glial Involvement Beyond the Glue
- (2015) Maha Elsayed et al. Frontiers in Cellular Neuroscience
- Astrocytes in Neurodegenerative Disease: Table 1.
- (2015) Hemali Phatnani et al. Cold Spring Harbor Perspectives in Biology
- Astrocytes Control Food Intake by Inhibiting AGRP Neuron Activity via Adenosine A1 Receptors
- (2015) Liang Yang et al. Cell Reports
- Chemogenetics—A Transformational and Translational Platform
- (2015) Justin G. English et al. JAMA Neurology
- The role of microglia in human disease: therapeutic tool or target?
- (2014) Nathalie Cartier et al. ACTA NEUROPATHOLOGICA
- Losartan prevents acquired epilepsy via TGF-β signaling suppression
- (2014) Guy Bar-Klein et al. ANNALS OF NEUROLOGY
- Chemogenetic Tools to Interrogate Brain Functions
- (2014) Scott M. Sternson et al. Annual Review of Neuroscience
- The subpopulation of microglia expressing functional muscarinic acetylcholine receptors expands in stroke and Alzheimer’s disease
- (2014) Maria Pannell et al. Brain Structure & Function
- Disruption of dopaminergic transmission remodels tripartite synapse morphology and astrocytic calcium activity within substantia nigra pars reticulata
- (2014) Anthony Bosson et al. GLIA
- The glia/neuron ratio: How it varies uniformly across brain structures and species and what that means for brain physiology and evolution
- (2014) Suzana Herculano-Houzel GLIA
- An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex
- (2014) Y. Zhang et al. JOURNAL OF NEUROSCIENCE
- Astrocyte-Derived BDNF Supports Myelin Protein Synthesis after Cuprizone-Induced Demyelination
- (2014) C. G. Fulmer et al. JOURNAL OF NEUROSCIENCE
- Astrocytic glycogenolysis: mechanisms and functions
- (2014) Leif Hertz et al. METABOLIC BRAIN DISEASE
- Decreased Astroglial Monocarboxylate Transporter 4 Expression in Temporal Lobe Epilepsy
- (2014) Bei Liu et al. MOLECULAR NEUROBIOLOGY
- Microglial priming in neurodegenerative disease
- (2014) V. Hugh Perry et al. Nature Reviews Neurology
- Adenosine A2A receptor antagonism reverses inflammation-induced impairment of microglial process extension in a model of Parkinson's disease
- (2014) Stefka Gyoneva et al. NEUROBIOLOGY OF DISEASE
- Basic Mechanism Leading to Stimulation of Glycogenolysis by Isoproterenol, EGF, Elevated Extracellular K+ Concentrations, or GABA
- (2014) Junnan Xu et al. NEUROCHEMICAL RESEARCH
- Reactive Gliosis and the Multicellular Response to CNS Damage and Disease
- (2014) Joshua E. Burda et al. NEURON
- Colony-Stimulating Factor 1 Receptor Signaling Is Necessary for Microglia Viability, Unmasking a Microglia Progenitor Cell in the Adult Brain
- (2014) Monica R.P. Elmore et al. NEURON
- Spinal HMGB1 induces TLR4-mediated long-lasting hypersensitivity and glial activation and regulates pain-like behavior in experimental arthritis
- (2014) Nilesh M. Agalave et al. PAIN
- GABAB receptor-mediated activation of astrocytes by gamma-hydroxybutyric acid
- (2014) T. Gould et al. PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES
- Lactate promotes plasticity gene expression by potentiating NMDA signaling in neurons
- (2014) J. Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Metabotropic P2Y1 receptor signalling mediates astrocytic hyperactivity in vivo in an Alzheimer’s disease mouse model
- (2014) Andrea Delekate et al. Nature Communications
- Inflammatory components in human Alzheimer’s disease and after active amyloid-β42 immunization
- (2013) Elina Zotova et al. BRAIN
- Microglia Promote Learning-Dependent Synapse Formation through Brain-Derived Neurotrophic Factor
- (2013) Christopher N. Parkhurst et al. CELL
- α1-Adrenergic receptors mediate coordinated Ca2+ signaling of cortical astrocytes in awake, behaving mice
- (2013) Fengfei Ding et al. CELL CALCIUM
- The multifaceted role of glial cells in amyotrophic lateral sclerosis
- (2013) Chiara F. Valori et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism
- (2013) K. H. Lauritzen et al. CEREBRAL CORTEX
- Astrocytes inhibit nitric oxide-dependent Ca2+dynamics in activated microglia: Involvement of ATP released via pannexin 1 channels
- (2013) Juan A. Orellana et al. GLIA
- β-amyloid and ATP-induced diffusional trapping of astrocyte and neuronal metabotropic glutamate type-5 receptors
- (2013) Amulya Nidhi Shrivastava et al. GLIA
- Norepinephrine Modulates the Motility of Resting and Activated Microglia via Different Adrenergic Receptors
- (2013) Stefka Gyoneva et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Adenosine A2A Receptor Contributes to Ischemic Brain Damage in Newborn Piglet
- (2013) Zeng-Jin Yang et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Photolysis of Caged Ca2+ But Not Receptor-Mediated Ca2+ Signaling Triggers Astrocytic Glutamate Release
- (2013) F. Wang et al. JOURNAL OF NEUROSCIENCE
- Modulation of the autonomic nervous system and behaviour by acute glial cell Gqprotein-coupled receptor activationin vivo
- (2013) Cendra Agulhon et al. JOURNAL OF PHYSIOLOGY-LONDON
- Reciprocal Modulation Between Microglia and Astrocyte in Reactive Gliosis Following the CNS Injury
- (2013) Zhongwen Gao et al. MOLECULAR NEUROBIOLOGY
- Astrocyte-derived ATP modulates depressive-like behaviors
- (2013) Xiong Cao et al. NATURE MEDICINE
- Microglial P2Y12 Deficiency/Inhibition Protects against Brain Ischemia
- (2013) Corey M. Webster et al. PLoS One
- Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve injury
- (2012) Kimiko Kobayashi et al. GLIA
- The “quad-partite” synapse: Microglia-synapse interactions in the developing and mature CNS
- (2012) Dorothy P. Schafer et al. GLIA
- Inflammatory Mediators Alter the Astrocyte Transcriptome and Calcium Signaling Elicited by Multiple G-Protein-Coupled Receptors
- (2012) M. E. Hamby et al. JOURNAL OF NEUROSCIENCE
- Astrocyte-Neuron Lactate Transport Is Required for Long-Term Memory Formation
- (2011) Akinobu Suzuki et al. CELL
- Hyperalgesia by synaptic long-term potentiation (LTP): an update
- (2011) Jürgen Sandkühler et al. CURRENT OPINION IN PHARMACOLOGY
- Adeno-Associated Virus Serotype 9 Transduction in the Central Nervous System of Nonhuman Primates
- (2011) Lluis Samaranch et al. HUMAN GENE THERAPY
- The BH4 domain of Bcl-XL rescues astrocyte degeneration in amyotrophic lateral sclerosis by modulating intracellular calcium signals
- (2011) Francesca Martorana et al. HUMAN MOLECULAR GENETICS
- Deletion of the murine scavenger receptor CD68
- (2011) Li Song et al. JOURNAL OF LIPID RESEARCH
- Neuronal and microglial mechanisms of neuropathic pain
- (2011) Min Zhuo et al. Molecular Brain
- Cortical hypometabolism and hypoperfusion in Parkinson’s disease is extensive: probably even at early disease stages
- (2010) Per Borghammer et al. Brain Structure & Function
- Astrocyte heterogeneity: an underappreciated topic in neurobiology
- (2010) Ye Zhang et al. CURRENT OPINION IN NEUROBIOLOGY
- Glial and neuronal control of brain blood flow
- (2010) David Attwell et al. NATURE
- Selective induction of astrocytic gliosis generates deficits in neuronal inhibition
- (2010) Pavel I Ortinski et al. NATURE NEUROSCIENCE
- Adrenoceptors in brain: Cellular gene expression and effects on astrocytic metabolism and [Ca2+]i
- (2010) Leif Hertz et al. NEUROCHEMISTRY INTERNATIONAL
- Hippocampal Short- and Long-Term Plasticity Are Not Modulated by Astrocyte Ca2+ Signaling
- (2010) C. Agulhon et al. SCIENCE
- Astrocytes: biology and pathology
- (2009) Michael V. Sofroniew et al. ACTA NEUROPATHOLOGICA
- Activation of metabotropic glutamate receptor 5 improves recovery after spinal cord injury in rodents
- (2009) Kimberly R. Byrnes et al. ANNALS OF NEUROLOGY
- The Glial Nature of Embryonic and Adult Neural Stem Cells
- (2009) Arnold Kriegstein et al. Annual Review of Neuroscience
- A potential role for pro-inflammatory cytokines in regulating synaptic plasticity in major depressive disorder
- (2009) Rushaniya A. Khairova et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Neuroscience: Glia — more than just brain glue
- (2009) Nicola J. Allen et al. NATURE
- Temporally precise in vivo control of intracellular signalling
- (2009) Raag D. Airan et al. NATURE
- Adenosine A2A receptor mediates microglial process retraction
- (2009) Anna G Orr et al. NATURE NEUROSCIENCE
- Melatonin Promotes Oligodendroglial Maturation of Injured White Matter in Neonatal Rats
- (2009) Paul Olivier et al. PLoS One
- A chemical-genetic approach to study G protein regulation of β cell function in vivo
- (2009) Jean-Marc Guettier et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Synchronous Hyperactivity and Intercellular Calcium Waves in Astrocytes in Alzheimer Mice
- (2009) K. V. Kuchibhotla et al. SCIENCE
- Prostaglandin E2 released from activated microglia enhances astrocyte proliferation in vitro
- (2009) Dan Zhang et al. TOXICOLOGY AND APPLIED PHARMACOLOGY
- Engineered G-protein coupled receptors are powerful tools to investigate biological processes and behaviors
- (2009) Charles D. Nichols Frontiers in Molecular Neuroscience
- Kinetics of G-protein-coupled receptor signals in intact cells
- (2008) M J Lohse et al. BRITISH JOURNAL OF PHARMACOLOGY
- Developmental profile and mechanisms of GABA-induced calcium signaling in hippocampal astrocytes
- (2008) Silke D. Meier et al. GLIA
- Cerebral blood flow abnormality in patients with idiopathic generalized epilepsy
- (2008) E. Y. Joo et al. JOURNAL OF NEUROLOGY
- Two Forms of Astrocyte Calcium Excitability Have Distinct Effects on NMDA Receptor-Mediated Slow Inward Currents in Pyramidal Neurons
- (2008) E. Shigetomi et al. JOURNAL OF NEUROSCIENCE
- P2Y12 Receptor Upregulation in Activated Microglia Is a Gateway of p38 Signaling and Neuropathic Pain
- (2008) K. Kobayashi et al. JOURNAL OF NEUROSCIENCE
- Status Epilepticus Induces a Particular Microglial Activation State Characterized by Enhanced Purinergic Signaling
- (2008) E. Avignone et al. JOURNAL OF NEUROSCIENCE
- A Transcriptome Database for Astrocytes, Neurons, and Oligodendrocytes: A New Resource for Understanding Brain Development and Function
- (2008) J. D. Cahoy et al. JOURNAL OF NEUROSCIENCE
- Akt activation is involved in P2Y12 receptor-mediated chemotaxis of microglia
- (2008) Yasuhiro Irino et al. JOURNAL OF NEUROSCIENCE RESEARCH
- Intravascular AAV9 preferentially targets neonatal neurons and adult astrocytes
- (2008) Kevin D Foust et al. NATURE BIOTECHNOLOGY
- Neuroglia: the 150 years after
- (2008) Helmut Kettenmann et al. TRENDS IN NEUROSCIENCES
Create your own webinar
Interested in hosting your own webinar? Check the schedule and propose your idea to the Peeref Content Team.
Create NowBecome a Peeref-certified reviewer
The Peeref Institute provides free reviewer training that teaches the core competencies of the academic peer review process.
Get Started