Chemogenetic stimulation of the G i pathway in astrocytes suppresses neuroinflammation

Emerging technologies to study glial cells

(2020) Hélène Hirbec et al.   GLIA

Distinct temporal integration of noradrenaline signaling by astrocytic second messengers during vigilance

(2020) Yuki Oe et al.   Nature Communications

Astrocytes contribute to remote memory formation by modulating hippocampal–cortical communication during learning

(2020) Adi Kol et al.   NATURE NEUROSCIENCE

Context-Specific Striatal Astrocyte Molecular Responses Are Phenotypically Exploitable

(2020) Xinzhu Yu et al.   NEURON

Microglial TonEBP mediates LPS-induced inflammation and memory loss as transcriptional cofactor for NF-κB and AP-1

(2020) Gyu Won Jeong et al.   Journal of Neuroinflammation

Astrocytic pyruvate dehydrogenase kinase-2 is involved in hypothalamic inflammation in mouse models of diabetes

(2020) Md Habibur Rahman et al.   Nature Communications

Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders

(2019) Eiji Shigetomi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Gi/o protein-coupled receptors inhibit neurons but activate astrocytes and stimulate gliotransmission

(2019) Caitlin A. Durkee et al.   GLIA

Hyperactivity with Disrupted Attention by Activation of an Astrocyte Synaptogenic Cue

(2019) Jun Nagai et al.   CELL

Neuroinflammation induced by lipopolysaccharide causes cognitive impairment in mice

(2019) Jiayi Zhao et al.   Scientific Reports

Activation of Astrocytic μ-Opioid Receptor Causes Conditioned Place Preference

(2019) Min-Ho Nam et al.   Cell Reports

Dopamine receptor D3 signalling in astrocytes promotes neuroinflammation

(2019) Andro Montoya et al.   Journal of Neuroinflammation

Astrocytic Activation Generates De Novo Neuronal Potentiation and Memory Enhancement

(2018) Adar Adamsky et al.   CELL

DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats

(2018) Peter M. Grace et al.   EXPERIMENTAL NEUROLOGY

Aberrant astrocyte Ca2+ signals “AxCa signals” exacerbate pathological alterations in an Alexander disease model

(2018) Kozo Saito et al.   GLIA

Astrocytes, neurons, synapses: a tripartite view on cortical circuit development

(2018) Isabella Farhy-Tselnicker et al.   Neural Development

Chemogenetic Manipulation of Dorsal Hippocampal Astrocytes Protects Against the Development of Stress-enhanced Fear Learning

(2018) Meghan E. Jones et al.   NEUROSCIENCE

Editorial: Neuroinflammation and Cognition

(2018) Ashok Kumar   Frontiers in Aging Neuroscience

Reactive Astrocytes: Production, Function, and Therapeutic Potential

(2017) Shane A. Liddelow et al.   IMMUNITY

Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence

(2017) Hua Chai et al.   NEURON

L-type voltage-operated calcium channels contribute to astrocyte activationIn vitro

(2016) Veronica T. Cheli et al.   GLIA

UDP-glucose promotes neutrophil recruitment in the lung

(2016) Juliana I. Sesma et al.   Purinergic Signalling

Probing the Complexities of Astrocyte Calcium Signaling

(2016) Eiji Shigetomi et al.   TRENDS IN CELL BIOLOGY

Astrocytes: a central element in neurological diseases

(2015) Milos Pekny et al.   ACTA NEUROPATHOLOGICA

DREADDs (Designer Receptors Exclusively Activated by Designer Drugs): Chemogenetic Tools with Therapeutic Utility

(2015) Daniel J. Urban et al.   Annual Review of Pharmacology and Toxicology

Disruption of IP3R2-mediated Ca2+ signaling pathway in astrocytes ameliorates neuronal death and brain damage while reducing behavioral deficits after focal ischemic stroke

(2015) Hailong Li et al.   CELL CALCIUM

Brain plasticity and cognitive functions after ethanol consumption in C57BL/6J mice

(2015) E Stragier et al.   Translational Psychiatry

Renal Intercalated Cells Sense and Mediate Inflammation via the P2Y14 Receptor

(2015) Anie Azroyan et al.   PLoS One

Role of astrocytic glycolytic metabolism in Alzheimer’s disease pathogenesis

(2014) Wen Fu et al.   BIOGERONTOLOGY

LPS and IL-1 differentially activate mouse and human astrocytes: Role of CD14

(2014) Leonid Tarassishin et al.   GLIA

Nucleotide signalling during inflammation

(2014) Marco Idzko et al.   NATURE

Smart Soup, a Traditional Chinese Medicine Formula, Ameliorates Amyloid Pathology and Related Cognitive Deficits

(2014) Yujun Hou et al.   PLoS One

Astrocytic modulation of blood brain barrier: perspectives on Parkinson’s disease

(2014) Ricardo Cabezas et al.   Frontiers in Cellular Neuroscience

The astrocyte in multiple sclerosis revisited

(2013) Celia F. Brosnan et al.   GLIA

Calcium-dependent N-cadherin up-regulation mediates reactive astrogliosis and neuroprotection after brain injury

(2013) K. Kanemaru et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Novel designer receptors to probe GPCR signaling and physiology

(2013) Jürgen Wess et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Secretion of Matrix Metalloproteinase-9 from Astrocytes by Inhibition of Tonic P2Y14-Receptor-Mediated Signal(s)

(2012) Manao Kinoshita et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Multiple P2Y subtypes in spinal microglia are involved in neuropathic pain after peripheral nerve injury

(2012) Kimiko Kobayashi et al.   GLIA

GPR105 Ablation Prevents Inflammation and Improves Insulin Sensitivity in Mice with Diet-Induced Obesity

(2012) J. Xu et al.   JOURNAL OF IMMUNOLOGY

Suppression of neuroinflammation by astrocytic dopamine D2 receptors via αB-crystallin

(2012) Wei Shao et al.   NATURE

Inhibition of human astrocyte and microglia neurotoxicity by calcium channel blockers

(2012) Sadayuki Hashioka et al.   NEUROPHARMACOLOGY

Lipocalin-2 Is a Chemokine Inducer in the Central Nervous System

(2011) Shinrye Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Naloxone and Ouabain in Ultralow Concentrations Restore Na+/K+-ATPase and Cytoskeleton in Lipopolysaccharide-treated Astrocytes

(2011) Johan Forshammar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Lipopolysaccharide modulates astrocytic S100B secretion: a study in cerebrospinal fluid and astrocyte cultures from rats

(2011) Maria Guerra et al.   Journal of Neuroinflammation

Lipopolysaccharide-induced inhibition of connexin43 gap junction communication in astrocytes is mediated by downregulation of caveolin-3

(2010) Chih-Kai Liao et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

IFN-β reverses the lipopolysaccharide-induced proteome modifications in treated astrocytes

(2010) Daniele Vergara et al.   JOURNAL OF NEUROIMMUNOLOGY

Inflammatory cytokine release of astrocytes in vitro is reduced by all-trans retinoic acid

(2010) Sabien van Neerven et al.   JOURNAL OF NEUROIMMUNOLOGY

Astrocytes: biology and pathology

(2009) Michael V. Sofroniew et al.   ACTA NEUROPATHOLOGICA

UDP-glucose acting at P2Y 14 receptors is a mediator of mast cell degranulation

(2009) Zhan-Guo Gao et al.   BIOCHEMICAL PHARMACOLOGY

Lipocalin-2 Is an Autocrine Mediator of Reactive Astrocytosis

(2009) S. Lee et al.   JOURNAL OF NEUROSCIENCE

Remote Control of Neuronal Activity in Transgenic Mice Expressing Evolved G Protein-Coupled Receptors

(2009) Georgia M. Alexander et al.   NEURON

A chemical-genetic approach to study G protein regulation of β cell function in vivo

(2009) Jean-Marc Guettier et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Na+/K+-ATPase-mediated signal transduction and Na+/K+-ATPase regulation

(2008) Linan Zhang et al.   FUNDAMENTAL & CLINICAL PHARMACOLOGY

Functional implications for Kir4.1 channels in glial biology: from K+buffering to cell differentiation

(2008) Michelle L. Olsen et al.   JOURNAL OF NEUROCHEMISTRY

Glial toll-like receptor signaling in central nervous system infection and autoimmunity

(2007) Pamela A. Carpentier et al.   BRAIN BEHAVIOR AND IMMUNITY

Neocortical glial cell numbers in human brains

(2007) D.P. Pelvig et al.   NEUROBIOLOGY OF AGING