Microglia P2Y6 receptor is related to Parkinson’s disease through neuroinflammatory process

Pharmacology and structure of P2Y receptors

(2016) Ivar von Kügelgen et al.   NEUROPHARMACOLOGY

Different danger signals differently impact on microglial proliferation through alterations of ATP release and extracellular metabolism

(2015) Jimmy George et al.   GLIA

P2Y6 Receptor-Mediated Microglial Phagocytosis in Radiation-Induced Brain Injury

(2015) Yongteng Xu et al.   MOLECULAR NEUROBIOLOGY

P2Y1 receptor mediated neuronal fibre outgrowth in organotypic brain slice co-cultures

(2015) Claudia Heine et al.   NEUROPHARMACOLOGY

Microglia Plasticity During Health and Disease: An Immunological Perspective

(2015) Anat Shemer et al.   TRENDS IN IMMUNOLOGY

Neuroinflammation in Parkinson’s disease and its potential as therapeutic target

(2015) Qinqin Wang et al.   Translational Neurodegeneration

P2Y receptors in Alzheimer's disease

(2014) Laurie Erb et al.   BIOLOGY OF THE CELL

Inhibition of UDP/P2Y6purinergic signaling prevents phagocytosis of viable neurons by activated microgliain vitroandin vivo

(2014) Jonas J. Neher et al.   GLIA

Intestinal Inflammation Increases the Expression of the P2Y6 Receptor on Epithelial Cells and the Release of CXC Chemokine Ligand 8 by UDP

(2014) D. M. Grbic et al.   JOURNAL OF IMMUNOLOGY

Extracellular UDP and P2Y6Function as a Danger Signal To Protect Mice from Vesicular Stomatitis Virus Infection through an Increase in IFN-β Production

(2014) Ruimei Li et al.   JOURNAL OF IMMUNOLOGY

Microglia P2Y6 receptors mediate nitric oxide release and astrocyte apoptosis

(2014) Clara Quintas et al.   Journal of Neuroinflammation

P2Y6 Receptor Potentiates Pro-Inflammatory Responses in Macrophages and Exhibits Differential Roles in Atherosclerotic Lesion Development

(2014) Ricardo A. Garcia et al.   PLoS One

Loss of P2Y2 Nucleotide Receptors Enhances Early Pathology in the TgCRND8 Mouse Model of Alzheimer's Disease

(2013) Deepa Ajit et al.   MOLECULAR NEUROBIOLOGY

The activation of P2Y6 receptor in cultured spinal microglia induces the production of CCL2 through the MAP kinases-NF-κB pathway

(2013) Norimitsu Morioka et al.   NEUROPHARMACOLOGY

Immunoregulation through extracellular nucleotides

(2012) L. Vitiello et al.   BLOOD

Purinergic receptors in microglia: Functional modal shifts of microglia mediated by P2 and P1 receptors

(2012) Schuichi Koizumi et al.   GLIA

A molecular signature in blood identifies early Parkinson’s disease

(2012) Leonid Molochnikov et al.   Molecular Neurodegeneration

Premotor biomarkers for Parkinson's disease - a promising direction of research

(2012) Brian R Haas et al.   Translational Neurodegeneration

Salivary α-synuclein and DJ-1: potential biomarkers for Parkinson's disease

(2011) Ivana Devic et al.   BRAIN

Uridine 5'-Diphosphate Induces Chemokine Expression in Microglia and Astrocytes through Activation of the P2Y6 Receptor

(2011) B. Kim et al.   JOURNAL OF IMMUNOLOGY

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

DJ-1 and α-synuclein in human cerebrospinal fluid as biomarkers of Parkinson’s disease

(2010) Zhen Hong et al.   BRAIN

Concomitant activation of P2Y2and P2Y6receptors on monocytes is required for TLR1/2-induced neutrophil migration by regulating IL-8 secretion

(2009) Fethia Ben Yebdri et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

P2Y6 receptor and immunoinflammation

(2009) Gui-Dong Liu et al.   Neuroscience Bulletin

Peripheral cytokines profile in Parkinson’s disease

(2008) M. Reale et al.   BRAIN BEHAVIOR AND IMMUNITY

Neuroinflammation mediated by IL-1β increases susceptibility of dopamine neurons to degeneration in an animal model of Parkinson's disease

(2008) James B Koprich et al.   Journal of Neuroinflammation

Second consensus statement on the diagnosis of multiple system atrophy

(2008) S. Gilman et al.   NEUROLOGY