Early stress-induced impaired microglial pruning of excitatory synapses on immature CRH-expressing neurons provokes aberrant adult stress responses

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(2021) Kazuo Emoto et al.   NEUROSCIENCE RESEARCH

Chemogenetic Activation of CX3CR1-Expressing Spinal Microglia Using Gq-DREADD Elicits Mechanical Allodynia in Male Mice

(2021) Fumihiro Saika et al.   Cells

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(2021) Anaelle Aurelie Dumas et al.   NEURON

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(2021) Yana Van Den Herrewegen et al.   Molecular Brain

Early Adversity and Development: Parsing Heterogeneity and Identifying Pathways of Risk and Resilience

(2021) Dylan G. Gee   AMERICAN JOURNAL OF PSYCHIATRY

Microglial-glucocorticoid receptor depletion alters the response of hippocampal microglia and neurons in a chronic unpredictable mild stress paradigm in female mice

(2021) Katherine Picard et al.   BRAIN BEHAVIOR AND IMMUNITY

Microglia Actively Remodel Adult Hippocampal Neurogenesis through the Phagocytosis Secretome

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Local externalization of phosphatidylserine mediates developmental synaptic pruning by microglia

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Neurodevelopmental Optimization after Early-Life Adversity: Cross-Species Studies to Elucidate Sensitive Periods and Brain Mechanisms to Inform Early Intervention

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Organotypic Brain Slice Culture Microglia Exhibit Molecular Similarity to Acutely-Isolated Adult Microglia and Provide a Platform to Study Neuroinflammation

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Unexpected Transcriptional Programs Contribute to Hippocampal Memory Deficits and Neuronal Stunting after Early-Life Adversity

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Programming of Stress-Sensitive Neurons and Circuits by Early-Life Experiences

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Long-term monocular deprivation during juvenile critical period disrupts binocular integration in mouse visual thalamus

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Plasticity of the Reward Circuitry After Early-Life Adversity: Mechanisms and Significance

(2019) Matthew T. Birnie et al.   BIOLOGICAL PSYCHIATRY

On the early life origins of vulnerability to opioid addiction

(2019) Sophia C. Levis et al.   MOLECULAR PSYCHIATRY

Anhedonia Following Early-Life Adversity Involves Aberrant Interaction of Reward and Anxiety Circuits and Is Reversed by Partial Silencing of Amygdala Corticotropin-Releasing Hormone Gene

(2018) Jessica L. Bolton et al.   BIOLOGICAL PSYCHIATRY

DREADDed microglia in pain: Implications for spinal inflammatory signaling in male rats

(2018) Peter M. Grace et al.   EXPERIMENTAL NEUROLOGY

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(2018) Anne E. Takesian et al.   NATURE NEUROSCIENCE

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(2018) Pinar Ayata et al.   NATURE NEUROSCIENCE

Socioeconomic status and the brain: prospects for neuroscience-informed policy

(2018) Martha J. Farah   NATURE REVIEWS NEUROSCIENCE

Astrocyte-derived interleukin-33 promotes microglial synapse engulfment and neural circuit development

(2018) Ilia D. Vainchtein et al.   SCIENCE

Microglia remodel synapses by presynaptic trogocytosis and spine head filopodia induction

(2018) Laetitia Weinhard et al.   Nature Communications

MERTK mediates intrinsic and adaptive resistance to AXL-targeting agents

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Single-Cell RNA Sequencing of Microglia throughout the Mouse Lifespan and in the Injured Brain Reveals Complex Cell-State Changes

(2018) Timothy R. Hammond et al.   IMMUNITY

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Converging, Synergistic Actions of Multiple Stress Hormones Mediate Enduring Memory Impairments after Acute Simultaneous Stresses

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(2016) Lawrence Fourgeaud et al.   NATURE

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(2016) Akiko Miyamoto et al.   Nature Communications

Microglial P2Y12 is necessary for synaptic plasticity in mouse visual cortex

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Correction: Neuronal Hyperactivity Disturbs ATP Microgradients, Impairs Microglial Motility, and Reduces Phagocytic Receptor Expression Triggering Apoptosis/Microglial Phagocytosis Uncoupling

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Diversity of Reporter Expression Patterns in Transgenic Mouse Lines Targeting Corticotropin-Releasing Hormone-Expressing Neurons

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(2015) Amir Pozner et al.   Frontiers in Molecular Neuroscience

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Neuronal Hyperactivity Recruits Microglial Processes via Neuronal NMDA Receptors and Microglial P2Y12 Receptors after Status Epilepticus

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Preferential loss of dorsal-hippocampus synapses underlies memory impairments provoked by short, multimodal stress

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(2014) Yang Zhan et al.   NATURE NEUROSCIENCE

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(2013) Dorothy P. Schafer et al.   CURRENT OPINION IN NEUROBIOLOGY

Dysfunctional Astrocytic and Synaptic Regulation of Hypothalamic Glutamatergic Transmission in a Mouse Model of Early-Life Adversity: Relevance to Neurosteroids and Programming of the Stress Response

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Microglia Are Essential to Masculinization of Brain and Behavior

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(2013) Won-Suk Chung et al.   NATURE

Functional Impairment of Microglia Coincides with Beta-Amyloid Deposition in Mice with Alzheimer-Like Pathology

(2013) Grietje Krabbe et al.   PLoS One

Deficiency of the Microglial Receptor CX3CR1 Impairs Postnatal Functional Development of Thalamocortical Synapses in the Barrel Cortex

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(2012) Johannes Schindelin et al.   NATURE METHODS

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Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

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Current research trends in early life stress and depression: Review of human studies on sensitive periods, gene–environment interactions, and epigenetics

(2011) Christine Heim et al.   EXPERIMENTAL NEUROLOGY

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(2011) Andrea Danese et al.   PHYSIOLOGY & BEHAVIOR

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

(2011) R. C. Paolicelli et al.   SCIENCE

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Trafficking and Surface Expression of Hyperpolarization-activated Cyclic Nucleotide-gated Channels in Hippocampal Neurons

(2010) Yoav Noam et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hippocampal Dysfunction and Cognitive Impairments Provoked by Chronic Early-Life Stress Involve Excessive Activation of CRH Receptors

(2010) A. S. Ivy et al.   JOURNAL OF NEUROSCIENCE

Microglial Interactions with Synapses Are Modulated by Visual Experience

(2010) Marie-Ève Tremblay et al.   PLOS BIOLOGY

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(2009) Thomas R. Insel   ARCHIVES OF GENERAL PSYCHIATRY

A Novel Mouse Model for Acute and Long-Lasting Consequences of Early Life Stress

(2008) Courtney J. Rice et al.   ENDOCRINOLOGY

Dysfunctional nurturing behavior in rat dams with limited access to nesting material: A clinically relevant model for early-life stress

(2008) A.S. Ivy et al.   NEUROSCIENCE

Altered Regulation of Gene and Protein Expression of Hypothalamic-Pituitary-Adrenal Axis Components in an Immature Rat Model of Chronic Stress

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