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Title
Mining genomes to illuminate the specialized chemistry of life
Authors
Keywords
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Journal
NATURE REVIEWS GENETICS
Volume 22, Issue 9, Pages 553-571
Publisher
Springer Science and Business Media LLC
Online
2021-06-04
DOI
10.1038/s41576-021-00363-7
References
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Note: Only part of the references are listed.- Convergent evolution of pain-inducing defensive venom components in spitting cobras
- (2021) T. D. Kazandjian et al. SCIENCE
- A community resource for paired genomic and metabolomic data mining
- (2021) Michelle A. Schorn et al. Nature Chemical Biology
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- (2021) Atanas G. Atanasov et al. NATURE REVIEWS DRUG DISCOVERY
- Cas12a-assisted precise targeted cloning using in vivo Cre-lox recombination
- (2021) Behnam Enghiad et al. Nature Communications
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- (2021) Tristan de Rond et al. Nature Chemical Biology
- A Pathogen-Responsive Gene Cluster for Highly Modified Fatty Acids in Tomato
- (2020) Ju Eun Jeon et al. CELL
- A Convolutional Neural Network-Based Approach for the Rapid Annotation of Molecularly Diverse Natural Products
- (2020) Raphael Reher et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- Ibotenic Acid Biosynthesis in the Fly Agaric Is Initiated by Glutamate Hydroxylation
- (2020) Michael Müller et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- A Deep Learning Approach to Antibiotic Discovery
- (2020) Jonathan M. Stokes et al. CELL
- ARTS 2.0: feature updates and expansion of the Antibiotic Resistant Target Seeker for comparative genome mining
- (2020) Mehmet Direnç Mungan et al. NUCLEIC ACIDS RESEARCH
- Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene
- (2020) Sandy S. Pineda et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The skin microbiome facilitates adaptive tetrodotoxin production in poisonous newts
- (2020) Patric M Vaelli et al. eLife
- Competition for iron drives phytopathogen control by natural rhizosphere microbiomes
- (2020) Shaohua Gu et al. Nature Microbiology
- Developmentally regulated volatiles geosmin and 2-methylisoborneol attract a soil arthropod to Streptomyces bacteria promoting spore dispersal
- (2020) Paul G. Becher et al. Nature Microbiology
- Synthetic-Bioinformatic Natural Product Antibiotics with Diverse Modes of Action
- (2020) John Chu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- In vitro prototyping and rapid optimization of biosynthetic enzymes for cell design
- (2020) Ashty S. Karim et al. Nature Chemical Biology
- Plant secondary metabolites as defenses, regulators, and primary metabolites: the blurred functional trichotomy
- (2020) Matthias Erb et al. PLANT PHYSIOLOGY
- Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface
- (2020) Uddhav K. Shigdel et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Animal biosynthesis of complex polyketides in a photosynthetic partnership
- (2020) Joshua P. Torres et al. Nature Communications
- Bioprospecting Through Cloning of Whole Natural Product Biosynthetic Gene Clusters
- (2020) Zhenquan Lin et al. Frontiers in Bioengineering and Biotechnology
- A machine-learning-based method for prediction of macrocyclization patterns of polyketides and nonribosomal peptides
- (2020) Priyesh Agrawal et al. BIOINFORMATICS
- Integrated omics unveil the secondary metabolic landscape of a basal dinoflagellate
- (2020) Girish Beedessee et al. BMC BIOLOGY
- Structure Prediction and Synthesis of Pyridine-Based Macrocyclic Peptide Natural Products
- (2020) Graham A. Hudson et al. ORGANIC LETTERS
- Transporter genes in biosynthetic gene clusters predict metabolite characteristics and siderophore activity
- (2020) Alexander Crits-Christoph et al. GENOME RESEARCH
- Comprehensive prediction of secondary metabolite structure and biological activity from microbial genome sequences
- (2020) Michael A. Skinnider et al. Nature Communications
- Expansion of RiPP biosynthetic space through integration of pan-genomics and machine learning uncovers a novel class of lanthipeptides
- (2020) Alexander M. Kloosterman et al. PLOS BIOLOGY
- rBAN: retro-biosynthetic analysis of nonribosomal peptides
- (2019) Emma Ricart et al. Journal of Cheminformatics
- Network-based microsynteny analysis identifies major differences and genomic outliers in mammalian and angiosperm genomes
- (2019) Tao Zhao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Drosophila melanogaster nonribosomal peptide synthetase Ebony encodes an atypical condensation domain
- (2019) Thierry Izoré et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Uncovering the unexplored diversity of thioamidated ribosomal peptides in Actinobacteria using the RiPPER genome mining tool
- (2019) Javier Santos-Aberturas et al. NUCLEIC ACIDS RESEARCH
- Discovery of a pathway for terminal-alkyne amino acid biosynthesis
- (2019) J. A. Marchand et al. NATURE
- Complete biosynthesis of cannabinoids and their unnatural analogues in yeast
- (2019) Xiaozhou Luo et al. NATURE
- An N-nitrosating metalloenzyme constructs the pharmacophore of streptozotocin
- (2019) Tai L. Ng et al. NATURE
- MAGI: A method for metabolite, annotation, and gene integration
- (2019) Onur Erbilgin et al. ACS Chemical Biology
- Scalable Biosynthesis of the Seaweed Neurochemical, Kainic Acid
- (2019) Jonathan R. Chekan et al. ANGEWANDTE CHEMIE-INTERNATIONAL EDITION
- antiSMASH 5.0: updates to the secondary metabolite genome mining pipeline
- (2019) Kai Blin et al. NUCLEIC ACIDS RESEARCH
- A specialized metabolic network selectively modulates Arabidopsis root microbiota
- (2019) Ancheng C. Huang et al. SCIENCE
- Culturing the Uncultured: Risk versus Reward
- (2019) J. Cameron Thrash mSystems
- Automated structure prediction of trans-acyltransferase polyketide synthase products
- (2019) Eric J. N. Helfrich et al. Nature Chemical Biology
- Use of a scaffold peptide in the biosynthesis of amino acid–derived natural products
- (2019) Chi P. Ting et al. SCIENCE
- A microbial factory for defensive kahalalides in a tripartite marine symbiosis
- (2019) Jindong Zan et al. SCIENCE
- Bioactive Synthetic-Bioinformatic Natural Product Cyclic Peptides Inspired by Nonribosomal Peptide Synthetase Gene Clusters from the Human Microbiome
- (2019) John Chu et al. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
- A deep learning genome-mining strategy for biosynthetic gene cluster prediction
- (2019) Geoffrey D Hannigan et al. NUCLEIC ACIDS RESEARCH
- The EFI Web Resource for Genomic Enzymology Tools: Leveraging Protein, Genome, and Metagenome Databases to Discover Novel Enzymes and Metabolic Pathways
- (2019) Rémi Zallot et al. BIOCHEMISTRY
- The manifold roles of microbial ribosomal peptide–based natural products in physiology and ecology
- (2019) Yanyan Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2019) Jorge C. Navarro-Muñoz et al. Nature Chemical Biology
- Drivers of metabolic diversification: how dynamic genomic neighborhoods generate new biosynthetic pathways in the Brassicaceae
- (2019) Zhenhua Liu et al. NEW PHYTOLOGIST
- Pathogen-induced activation of disease-suppressive functions in the endophytic root microbiome
- (2019) Víctor J. Carrión et al. SCIENCE
- NeuRiPP: Neural network identification of RiPP precursor peptides
- (2019) Emmanuel L. C. de los Santos Scientific Reports
- The Natural Products Atlas: An Open Access Knowledge Base for Microbial Natural Products Discovery
- (2019) Jeffrey A. van Santen et al. ACS Central Science
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- (2019) Gaoyan Wang et al. Nature Microbiology
- DeepRiPP integrates multiomics data to automate discovery of novel ribosomally synthesized natural products
- (2019) Nishanth J. Merwin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- MetaMiner: A Scalable Peptidogenomics Approach for Discovery of Ribosomal Peptide Natural Products with Blind Modifications from Microbial Communities
- (2019) Liu Cao et al. Cell Systems
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- (2018) Ben O Oyserman et al. CURRENT OPINION IN MICROBIOLOGY
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- (2018) Emile Gluck-Thaler et al. ISME Journal
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- (2018) Abraham J. Waldman et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2018) Alexander Crits-Christoph et al. NATURE
- Biosynthesis of redox-active metabolites in response to iron deficiency in plants
- (2018) Jakub Rajniak et al. Nature Chemical Biology
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- (2018) Auke J van Heel et al. NUCLEIC ACIDS RESEARCH
- Missing enzymes in the biosynthesis of the anticancer drug vinblastine in Madagascar periwinkle
- (2018) Lorenzo Caputi et al. SCIENCE
- Natural noncanonical protein splicing yields products with diverse β-amino acid residues
- (2018) Brandon I. Morinaka et al. SCIENCE
- Self-resistance guided genome mining uncovers new topoisomerase inhibitors from myxobacteria
- (2018) Fabian Panter et al. Chemical Science
- A comprehensive evaluation of module detection methods for gene expression data
- (2018) Wouter Saelens et al. Nature Communications
- Increased diversity of peptidic natural products revealed by modification-tolerant database search of mass spectra
- (2018) Alexey Gurevich et al. Nature Microbiology
- Culture-independent discovery of the malacidins as calcium-dependent antibiotics with activity against multidrug-resistant Gram-positive pathogens
- (2018) Bradley M. Hover et al. Nature Microbiology
- HEx: A heterologous expression platform for the discovery of fungal natural products
- (2018) Colin J. B. Harvey et al. Science Advances
- Resistance-gene-directed discovery of a natural-product herbicide with a new mode of action
- (2018) Yan Yan et al. NATURE
- A naturally occurring antiviral ribonucleotide encoded by the human genome
- (2018) Anthony S. Gizzi et al. NATURE
- Microbial Interkingdom Interactions in Roots Promote Arabidopsis Survival
- (2018) Paloma Durán et al. CELL
- Biochemical characterization of the minimal domains of an iterative eukaryotic polyketide synthase
- (2018) Martin Sabatini et al. FEBS Journal
- Escherichia coli “Marionette” strains with 12 highly optimized small-molecule sensors
- (2018) Adam J. Meyer et al. Nature Chemical Biology
- Fungal secondary metabolism: regulation, function and drug discovery
- (2018) Nancy P. Keller NATURE REVIEWS MICROBIOLOGY
- The antiSMASH database version 2: a comprehensive resource on secondary metabolite biosynthetic gene clusters
- (2018) Kai Blin et al. NUCLEIC ACIDS RESEARCH
- Gene-guided discovery and engineering of branched cyclic peptides in plants
- (2018) Roland D. Kersten et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Flavonols control pollen tube growth and integrity by regulating ROS homeostasis during high-temperature stress
- (2018) Joëlle K. Muhlemann et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism
- (2018) James Peek et al. Nature Communications
- Integrated culturing, modeling and transcriptomics uncovers complex interactions and emergent behavior in a three-species synthetic gut community
- (2018) Kevin D'hoe et al. eLife
- Function-related replacement of bacterial siderophore pathways
- (2017) Hilke Bruns et al. ISME Journal
- A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules
- (2017) James Reed et al. METABOLIC ENGINEERING
- Methanobactins: from genome to function
- (2017) Laura M. K. Dassama et al. Metallomics
- A new genome-mining tool redefines the lasso peptide biosynthetic landscape
- (2017) Jonathan I Tietz et al. Nature Chemical Biology
- A heme-dependent enzyme forms the nitrogen–nitrogen bond in piperazate
- (2017) Yi-Ling Du et al. Nature Chemical Biology
- Metagenomic discovery of polybrominated diphenyl ether biosynthesis by marine sponges
- (2017) Vinayak Agarwal et al. Nature Chemical Biology
- PRISM 3: expanded prediction of natural product chemical structures from microbial genomes
- (2017) Michael A. Skinnider et al. NUCLEIC ACIDS RESEARCH
- plantiSMASH: automated identification, annotation and expression analysis of plant biosynthetic gene clusters
- (2017) Satria A. Kautsar et al. NUCLEIC ACIDS RESEARCH
- ClusterCAD: a computational platform for type I modular polyketide synthase design
- (2017) Clara H Eng et al. NUCLEIC ACIDS RESEARCH
- A Global Coexpression Network Approach for Connecting Genes to Specialized Metabolic Pathways in Plants
- (2017) Jennifer H. Wisecaver et al. PLANT CELL
- Genome-Wide Prediction of Metabolic Enzymes, Pathways, and Gene Clusters in Plants
- (2017) Pascal Schläpfer et al. PLANT PHYSIOLOGY
- Statistical reanalysis of natural products reveals increasing chemical diversity
- (2017) Michael A. Skinnider et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Comparative genomics uncovers the prolific and distinctive metabolic potential of the cyanobacterial genusMoorea
- (2017) Tiago Leao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Unearthing a sesterterpene biosynthetic repertoire in the Brassicaceae through genome mining reveals convergent evolution
- (2017) Ancheng C. Huang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Retrospective analysis of natural products provides insights for future discovery trends
- (2017) Cameron R. Pye et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A prominent glycyl radical enzyme in human gut microbiomes metabolizestrans-4-hydroxy-l-proline
- (2017) B. J. Levin et al. SCIENCE
- Programmable DNA-Guided Artificial Restriction Enzymes
- (2017) Behnam Enghiad et al. ACS Synthetic Biology
- Resistance Gene-Guided Genome Mining: Serial Promoter Exchanges in Aspergillus nidulans Reveal the Biosynthetic Pathway for Fellutamide B, a Proteasome Inhibitor
- (2016) Hsu-Hua Yeh et al. ACS Chemical Biology
- Class of cyclic ribosomal peptide synthetic genes in filamentous fungi
- (2016) Nozomi Nagano et al. FUNGAL GENETICS AND BIOLOGY
- Phylogenomic Analysis of Natural Products Biosynthetic Gene Clusters Allows Discovery of Arseno-Organic Metabolites in Model Streptomycetes
- (2016) Pablo Cruz-Morales et al. Genome Biology and Evolution
- Sequencing rare marine actinomycete genomes reveals high density of unique natural product biosynthetic gene clusters
- (2016) Michelle A. Schorn et al. MICROBIOLOGY-SGM
- Deep Learning Applications for Predicting Pharmacological Properties of Drugs and Drug Repurposing Using Transcriptomic Data
- (2016) Alexander Aliper et al. MOLECULAR PHARMACEUTICS
- Computational genomic identification and functional reconstitution of plant natural product biosynthetic pathways
- (2016) Marnix H. Medema et al. NATURAL PRODUCT REPORTS
- The evolution of genome mining in microbes – a review
- (2016) Nadine Ziemert et al. NATURAL PRODUCT REPORTS
- Dereplication, sequencing and identification of peptidic natural products: from genome mining to peptidogenomics to spectral networks
- (2016) Hosein Mohimani et al. NATURAL PRODUCT REPORTS
- Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking
- (2016) Mingxun Wang et al. NATURE BIOTECHNOLOGY
- A hybrid polyketide–nonribosomal peptide in nematodes that promotes larval survival
- (2016) Qingyao Shou et al. Nature Chemical Biology
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- (2016) Chris A Dejong et al. Nature Chemical Biology
- Plant-like biosynthesis of isoquinoline alkaloids in Aspergillus fumigatus
- (2016) Joshua A Baccile et al. Nature Chemical Biology
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- (2016) John Chu et al. Nature Chemical Biology
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- (2016) Michael F. Freeman et al. Nature Chemistry
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- (2016) Tiago Rodrigues et al. Nature Chemistry
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- (2016) Michael J. Smanski et al. NATURE REVIEWS MICROBIOLOGY
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- (2016) Hans-Wilhelm Nützmann et al. NEW PHYTOLOGIST
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- (2016) Franziska Beran et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2016) Dan Luo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2016) Justin Johan Jozias van der Hooft et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2016) Elise A. R. Serin et al. Frontiers in Plant Science
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- (2016) Wouter Suring et al. Biology Open
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- (2016) Anthony W. Goering et al. ACS Central Science
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- (2015) Xiaoyu Tang et al. ACS Chemical Biology
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- (2015) Katherine R. Duncan et al. CHEMISTRY & BIOLOGY
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- (2015) Poochit Nonejuie et al. JOURNAL OF ANTIBIOTICS
- A new cyanogenic metabolite in Arabidopsis required for inducible pathogen defence
- (2015) Jakub Rajniak et al. NATURE
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- (2015) Marnix H Medema et al. Nature Chemical Biology
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- (2015) Marnix H Medema et al. Nature Chemical Biology
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- (2015) Nicholas C.O. Lee et al. NUCLEIC ACIDS RESEARCH
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- (2015) Kou-San Ju et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2015) Kenji L. Kurita et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2015) S. Galanie et al. SCIENCE
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- (2015) Warren Lau et al. SCIENCE
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- (2014) Micheal C. Wilson et al. NATURE
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- (2014) Michael J Smanski et al. NATURE BIOTECHNOLOGY
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- (2013) M. Itkin et al. SCIENCE
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- (2012) Juan Pablo Gomez-Escribano et al. Chemical Science
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- (2010) Man H. Chow et al. EUKARYOTIC CELL
- Ziconotide for treatment of severe chronic pain
- (2010) Achim Schmidtko et al. LANCET
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- (2010) J. Claesen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2009) Jayne E Rattray et al. Biology Direct
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- (2009) Masayuki Satake et al. JOURNAL OF ORGANIC CHEMISTRY
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- (2009) Jin Woo Bok et al. Nature Chemical Biology
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- (2009) BJ��RN USADEL et al. PLANT CELL AND ENVIRONMENT
- WGCNA: an R package for weighted correlation network analysis
- (2008) Peter Langfelder et al. BMC BIOINFORMATICS
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- (2008) C. Corre et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2008) B. Field et al. SCIENCE
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