Discovery of phosphonic acid natural products by mining the genomes of 10,000 actinomycetes

Elicitation of secondary metabolism in actinomycetes

(2015) Usama Ramadan Abdelmohsen et al.   BIOTECHNOLOGY ADVANCES

Discovery of Clostrubin, an Exceptional Polyphenolic Polyketide Antibiotic from a Strictly Anaerobic Bacterium

(2014) Sacha Pidot et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

New Aminocoumarins from the Rare ActinomyceteCatenulispora acidiphilaDSM 44928: Identification, Structure Elucidation, and Heterologous Production

(2014) Judith Zettler et al.   CHEMBIOCHEM

Recent advances in natural product discovery

(2014) Yunzi Luo et al.   CURRENT OPINION IN BIOTECHNOLOGY

Identification of the biosynthetic gene cluster for the herbicide phosphonothrixin in Saccharothrix sp. ST-888

(2014) Jianwen Lin et al.   JOURNAL OF ANTIBIOTICS

Purification and Characterization of Phosphonoglycans from Glycomyces sp. Strain NRRL B-16210 and Stackebrandtia nassauensis NRRL B-16338

(2014) X. Yu et al.   JOURNAL OF BACTERIOLOGY

Cyanohydrin Phosphonate Natural Product from Streptomyces regensis

(2014) Joel P. Cioni et al.   JOURNAL OF NATURAL PRODUCTS

Utilization of Glyphosate as Phosphate Source: Biochemistry and Genetics of Bacterial Carbon-Phosphorus Lyase

(2014) B. Hove-Jensen et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Secondary metabolomics: the impact of mass spectrometry-based approaches on the discovery and characterization of microbial natural products

(2014) Daniel Krug et al.   NATURAL PRODUCT REPORTS

A roadmap for natural product discovery based on large-scale genomics and metabolomics

(2014) James R Doroghazi et al.   Nature Chemical Biology

Discovery of the Antibiotic Phosacetamycin via a New Mass Spectrometry-Based Method for Phosphonic Acid Detection

(2013) Bradley S. Evans et al.   ACS Chemical Biology

Use of a Phosphonate Methyltransferase in the Identification of the Fosfazinomycin Biosynthetic Gene Cluster

(2013) Jiangtao Gao et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Natural products: A continuing source of novel drug leads

(2013) Gordon M. Cragg et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?

(2013) Brian O. Bachmann et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Genomics-enabled discovery of phosphonate natural products and their biosynthetic pathways

(2013) Kou-San Ju et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Discovery of indolotryptoline antiproliferative agents by homology-guided metagenomic screening

(2013) F.-Y. Chang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Revisiting the biosynthesis of dehydrophos reveals a tRNA-dependent pathway

(2013) D. J. Bougioukou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity and abundance of phosphonate biosynthetic genes in nature

(2013) X. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products

(2013) J. G. Owen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

IDBA-UD: a de novo assembler for single-cell and metagenomic sequencing data with highly uneven depth

(2012) Y. Peng et al.   BIOINFORMATICS

Thoughts and facts about antibiotics: Where we are now and where we are heading

(2012) János Bérdy   JOURNAL OF ANTIBIOTICS

The Antibiotic Dehydrophos Is Converted to a Toxic Pyruvate Analog by Peptide Bond Cleavage in Salmonella enterica

(2011) Benjamin T. Circello et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Genome Sequences of Three Tunicamycin-Producing Streptomyces Strains, S. chartreusis NRRL 12338, S. chartreusis NRRL 3882, and S. lysosuperificus ATCC 31396

(2011) J. R. Doroghazi et al.   JOURNAL OF BACTERIOLOGY

Expanding Small-Molecule Functional Metagenomics through Parallel Screening of Broad-Host-Range Cosmid Environmental DNA Libraries in Diverse Proteobacteria

(2010) J. W. Craig et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Prodigal: prokaryotic gene recognition and translation initiation site identification

(2010) Doug Hyatt et al.   BMC BIOINFORMATICS

Biosynthesis of Rhizocticins, Antifungal Phosphonate Oligopeptides Produced by Bacillus subtilis ATCC6633

(2010) Svetlana A. Borisova et al.   CHEMISTRY & BIOLOGY

NMR-spectroscopic analysis of mixtures: from structure to function

(2010) Ry R Forseth et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Postgenomic strategies in antibacterial drug discovery

(2010) Heike Brötz-Oesterhelt et al.   Future Microbiology

Substrate Specificity and Scope of MvdD, a GRASP-like Ligase from the Microviridin Biosynthetic Gene Cluster

(2009) Benjamin Philmus et al.   ACS Chemical Biology

Biosynthesis of Phosphonic and Phosphinic Acid Natural Products

(2009) William W. Metcalf et al.   Annual Review of Biochemistry

Cloning, Expression, and Biochemical Characterization of Streptomyces rubellomurinus Genes Required for Biosynthesis of Antimalarial Compound FR900098

(2008) Andrew C. Eliot et al.   CHEMISTRY & BIOLOGY

Genome Mining for Novel Natural Product Discovery

(2008) Gregory L. Challis   JOURNAL OF MEDICINAL CHEMISTRY