Discovery of Clostrubin, an Exceptional Polyphenolic Polyketide Antibiotic from a Strictly Anaerobic Bacterium

An environmental bacterial taxon with a large and distinct metabolic repertoire

(2014) Micheal C. Wilson et al.   NATURE

Formation of a Dinuclear Copper(I) Complex from theClostridium-Derived Antibiotic Closthioamide

(2013) Florian Kloss et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Developing new antibacterials through natural product research

(2013) Herbert A Kirst   Expert Opinion on Drug Discovery

Multidrug-resistant Tuberculosis

(2013) John B. Lynch   MEDICAL CLINICS OF NORTH AMERICA

Antiterminator-Mediated Unveiling of Cryptic Polythioamides in an Anaerobic Bacterium

(2012) Swantje Behnken et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Anaerobic bacteria as producers of antibiotics

(2012) Swantje Behnken et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Novel and neglected issues of acetone–butanol–ethanol (ABE) fermentation by clostridia: Clostridium metabolic diversity, tools for process mapping and continuous fermentation systems

(2012) Petra Patakova et al.   BIOTECHNOLOGY ADVANCES

Butanol production from lignocellulosics

(2012) German Jurgens et al.   BIOTECHNOLOGY LETTERS

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

A genomic approach to the cryptic secondary metabolome of the anaerobic world

(2012) Anne-Catrin Letzel et al.   NATURAL PRODUCT REPORTS

Cryptic Polyketide Synthase Genes in Non-Pathogenic Clostridium SPP

(2012) Swantje Behnken et al.   PLoS One

Significant Natural Product Biosynthetic Potential of Actinorhizal Symbionts of the Genus Frankia, as Revealed by Comparative Genomic and Proteomic Analyses

(2011) Daniel W. Udwary et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

Critical shortage of new antibiotics in development against multidrug-resistant bacteria—Time to react is now

(2011) Laura Freire-Moran et al.   DRUG RESISTANCE UPDATES

Highly Efficient Total Synthesis of the Clostridium-Derived anti-MRSA Antibiotic Closthioamide

(2011) Florian Kloss et al.   EUROPEAN JOURNAL OF ORGANIC CHEMISTRY

Tackling antibiotic resistance

(2011) Karen Bush et al.   NATURE REVIEWS MICROBIOLOGY

Closthioamide: An Unprecedented Polythioamide Antibiotic from the Strictly Anaerobic Bacterium Clostridium cellulolyticum

(2010) Thorger Lincke et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Genomics-inspired discovery of natural products

(2010) Jaclyn M Winter et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Entomopathogenic bacteria as a source of secondary metabolites

(2009) Helge B Bode   CURRENT OPINION IN CHEMICAL BIOLOGY

Genomic basis for natural product biosynthetic diversity in the actinomycetes

(2009) Markus Nett et al.   NATURAL PRODUCT REPORTS

Antibiotics for Emerging Pathogens

(2009) M. A. Fischbach et al.   SCIENCE

Benzopyrenomycin, a Cytotoxic Bacterial Polyketide Metabolite with a Benzo[a]pyrene-Type Carbocyclic Ring System

(2008) Xueshi Huang et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Fermentative butanol production by clostridia

(2008) Sang Yup Lee et al.   BIOTECHNOLOGY AND BIOENGINEERING

Orchestration of Discoid Polyketide Cyclization in the Resistomycin Pathway

(2008) Kathrin Fritzsche et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances

(2008) Irith Wiegand et al.   Nature Protocols