Structural venomics reveals evolution of a complex venom by duplication and diversification of an ancient peptide-encoding gene

The three-dimensional structure of an H-superfamily conotoxin reveals a granulin fold arising from a common ICK cysteine framework

(2019) Lau D. Nielsen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

True Lies: Using Proteomics to Assess the Accuracy of Transcriptome-Based Venomics in Centipedes Uncovers False Positives and Reveals Startling Intraspecific Variation in Scolopendra subspinipes

(2018) Jennifer Smith et al.   Toxins

The PRIDE database and related tools and resources in 2019: improving support for quantification data

(2018) Yasset Perez-Riverol et al.   NUCLEIC ACIDS RESEARCH

Revisiting venom of the sea anemone Stichodactyla haddoni : Omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus

(2017) Bruno Madio et al.   Journal of Proteomics

KNOTTIN: the database of inhibitor cystine knot scaffold after 10 years, toward a systematic structure modeling

(2017) Guillaume Postic et al.   NUCLEIC ACIDS RESEARCH

Potent neuroprotection after stroke afforded by a double-knot spider-venom peptide that inhibits acid-sensing ion channel 1a

(2017) Irène R. Chassagnon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Toxin structures as evolutionary tools: Using conserved 3D folds to study the evolution of rapidly evolving peptides

(2016) Eivind A. B. Undheim et al.   BIOESSAYS

The ProteomeXchange consortium in 2017: supporting the cultural change in proteomics public data deposition

(2016) Eric W. Deutsch et al.   NUCLEIC ACIDS RESEARCH

A molecular palaeobiological exploration of arthropod terrestrialization

(2016) Jesus Lozano-Fernandez et al.   PHILOSOPHICAL TRANSACTIONS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The insecticidal spider toxin SFI1 is a knottin peptide that blocks the pore of insect voltage-gated sodium channels via a large β-hairpin loop

(2015) Niraj S. Bende et al.   FEBS Journal

Isolation, N-glycosylations and Function of a Hyaluronidase-Like Enzyme from the Venom of the Spider Cupiennius salei

(2015) Olivier Biner et al.   PLoS One

Unexpected features of the dark proteome

(2015) Nelson Perdigão et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Cystine Knot Is Responsible for the Exceptional Stability of the Insecticidal Spider Toxin ω-Hexatoxin-Hv1a

(2015) Volker Herzig et al.   Toxins

Genomics Virtual Laboratory: A Practical Bioinformatics Workbench for the Cloud

(2015) Enis Afgan et al.   PLoS One

Trimmomatic: a flexible trimmer for Illumina sequence data

(2014) Anthony M. Bolger et al.   BIOINFORMATICS

Diversification of a single ancestral gene into a successful toxin superfamily in highly venomous Australian funnel-web spiders

(2014) Sandy S Pineda et al.   BMC GENOMICS

Phylogenomic Interrogation of Arachnida Reveals Systemic Conflicts in Phylogenetic Signal

(2014) Prashant P. Sharma et al.   MOLECULAR BIOLOGY AND EVOLUTION

IQ-TREE: A Fast and Effective Stochastic Algorithm for Estimating Maximum-Likelihood Phylogenies

(2014) Lam-Tung Nguyen et al.   MOLECULAR BIOLOGY AND EVOLUTION

A distinct sodium channel voltage-sensor locus determines insect selectivity of the spider toxin Dc1a

(2014) Niraj S. Bende et al.   Nature Communications

The insecticidal neurotoxin Aps III is an atypical knottin peptide that potently blocks insect voltage-gated sodium channels

(2013) Niraj S. Bende et al.   BIOCHEMICAL PHARMACOLOGY

Spit and Venom from Scytodes Spiders: A Diverse and Distinct Cocktail

(2013) Pamela A. Zobel-Thropp et al.   JOURNAL OF PROTEOME RESEARCH

Unravelling the complex venom landscapes of lethal Australian funnel-web spiders (Hexathelidae: Atracinae) using LC-MALDI-TOF mass spectrometry

(2013) Alexandre Palagi et al.   Journal of Proteomics

Ultrafast Approximation for Phylogenetic Bootstrap

(2013) B. Q. Minh et al.   MOLECULAR BIOLOGY AND EVOLUTION

MAFFT Multiple Sequence Alignment Software Version 7: Improvements in Performance and Usability

(2013) K. Katoh et al.   MOLECULAR BIOLOGY AND EVOLUTION

Production of Recombinant Disulfide-Rich Venom Peptides for Structural and Functional Analysis via Expression in the Periplasm of E. coli

(2013) Julie K. Klint et al.   PLoS One

Spider-Venom Peptides: Structure, Pharmacology, and Potential for Control of Insect Pests

(2012) Glenn F. King et al.   Annual Review of Entomology

CD-HIT: accelerated for clustering the next-generation sequencing data

(2012) Limin Fu et al.   BIOINFORMATICS

Natural and Engineered Cystine Knot Miniproteins for Diagnostic and Therapeutic Applications

(2012) Harald Kolmar   CURRENT PHARMACEUTICAL DESIGN

Deep Venomics Reveals the Mechanism for Expanded Peptide Diversity in Cone Snail Venom

(2012) Sébastien Dutertre et al.   MOLECULAR & CELLULAR PROTEOMICS

The Influence of Rate Heterogeneity among Sites on the Time Dependence of Molecular Rates

(2012) Julien Soubrier et al.   MOLECULAR BIOLOGY AND EVOLUTION

RSEM: accurate transcript quantification from RNA-Seq data with or without a reference genome

(2011) Bo Li et al.   BMC BIOINFORMATICS

Venoms as a platform for human drugs: translating toxins into therapeutics

(2011) Glenn F King   EXPERT OPINION ON BIOLOGICAL THERAPY

Full-length transcriptome assembly from RNA-Seq data without a reference genome

(2011) Manfred G Grabherr et al.   NATURE BIOTECHNOLOGY

SignalP 4.0: discriminating signal peptides from transmembrane regions

(2011) Thomas Nordahl Petersen et al.   NATURE METHODS

Unique scorpion toxin with a putative ancestral fold provides insight into evolution of the inhibitor cystine knot motif

(2011) J. J. Smith et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

How Many Species Are There on Earth and in the Ocean?

(2011) Camilo Mora et al.   PLOS BIOLOGY

The venom composition of the parasitic wasp Chelonus inanitus resolved by combined expressed sequence tags analysis and proteomic approach

(2010) Bruno Vincent et al.   BMC GENOMICS

A Bivalent Tarantula Toxin Activates the Capsaicin Receptor, TRPV1, by Targeting the Outer Pore Domain

(2010) Christopher J. Bohlen et al.   CELL

Chemical Synthesis and Structure of the Prokineticin Bv8

(2010) Rodrigo A. V. Morales et al.   CHEMBIOCHEM

Insights into the venom composition of the ectoparasitoid waspNasonia vitripennisfrom bioinformatic and proteomic studies

(2010) D. C. de Graaf et al.   INSECT MOLECULAR BIOLOGY

A non-uniformly sampled 4D HCC(CO)NH-TOCSY experiment processed using maximum entropy for rapid protein sidechain assignment

(2010) Mehdi Mobli et al.   JOURNAL OF MAGNETIC RESONANCE

MolProbity: all-atom structure validation for macromolecular crystallography

(2009) Vincent B. Chen et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

The Toxicogenomic Multiverse: Convergent Recruitment of Proteins Into Animal Venoms

(2009) Bryan G. Fry et al.   Annual Review of Genomics and Human Genetics

TALOS+: a hybrid method for predicting protein backbone torsion angles from NMR chemical shifts

(2009) Yang Shen et al.   JOURNAL OF BIOMOLECULAR NMR

Venomics: unravelling the complexity of animal venoms with mass spectrometry

(2008) P. Escoubas et al.   JOURNAL OF MASS SPECTROMETRY

Discovery of a Distinct Superfamily of Kunitz-Type Toxin (KTT) from Tarantulas

(2008) Chun-Hua Yuan et al.   PLoS One

NMR-spectroscopic screening of spider venom reveals sulfated nucleosides as major components for the brown recluse and related species

(2008) F. C. Schroeder et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A rational nomenclature for naming peptide toxins from spiders and other venomous animals

(2008) Glenn F. King et al.   TOXICON