Sequencing rare marine actinomycete genomes reveals high density of unique natural product biosynthetic gene clusters

Next Generation Sequencing of Actinobacteria for the Discovery of Novel Natural Products

(2016) Juan Gomez-Escribano et al.   Marine Drugs

Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees

(2016) Ivica Letunic et al.   NUCLEIC ACIDS RESEARCH

Identification of Thiotetronic Acid Antibiotic Biosynthetic Pathways by Target-directed Genome Mining

(2015) Xiaoyu Tang et al.   ACS Chemical Biology

Nocardiopsisspecies: a potential source of bioactive compounds

(2015) T. Bennur et al.   JOURNAL OF APPLIED MICROBIOLOGY

The marine actinomycete genus Salinispora: a model organism for secondary metabolite discovery

(2015) Paul R. Jensen et al.   NATURAL PRODUCT REPORTS

Minimum Information about a Biosynthetic Gene cluster

(2015) Marnix H Medema et al.   Nature Chemical Biology

Computational approaches to natural product discovery

(2015) Marnix H Medema et al.   Nature Chemical Biology

antiSMASH 3.0—a comprehensive resource for the genome mining of biosynthetic gene clusters

(2015) Tilmann Weber et al.   NUCLEIC ACIDS RESEARCH

Genome mining of rare actinomycetes and cryptic pathway awakening

(2015) Si-Sun Choi et al.   PROCESS BIOCHEMISTRY

IMG-ABC: A Knowledge Base To Fuel Discovery of Biosynthetic Gene Clusters and Novel Secondary Metabolites

(2015) Michalis Hadjithomas et al.   mBio

Filamentous fungi from extreme environments as a promising source of novel bioactive secondary metabolites

(2015) Renato Chávez et al.   Frontiers in Microbiology

Quality scores for 32,000 genomes

(2015) Miriam L Land et al.   Standards in Genomic Sciences

New antibacterial xanthone from the marine sponge-derived Micrococcus sp. EG45

(2014) Enas E. Eltamany et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Insights into Secondary Metabolism from a Global Analysis of Prokaryotic Biosynthetic Gene Clusters

(2014) Peter Cimermancic et al.   CELL

Dermacozines H–J Isolated from a Deep-Sea Strain of Dermacoccus abyssi from Mariana Trench Sediments

(2014) Marcell Wagner et al.   JOURNAL OF NATURAL PRODUCTS

A roadmap for natural product discovery based on large-scale genomics and metabolomics

(2014) James R Doroghazi et al.   Nature Chemical Biology

Terpene synthases are widely distributed in bacteria

(2014) Yuuki Yamada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Seriniquinone, a selective anticancer agent, induces cell death by autophagocytosis, targeting the cancer-protective protein dermcidin

(2014) L. Trzoss et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct cloning and refactoring of a silent lipopeptide biosynthetic gene cluster yields the antibiotic taromycin A

(2014) Kazuya Yamanaka et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Diversity and evolution of secondary metabolism in the marine actinomycete genus Salinispora

(2014) N. Ziemert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Discovering new bioactive molecules from microbial sources

(2014) Paolo Monciardini et al.   Microbial Biotechnology

Culturable rare Actinomycetes: diversity, isolation and marine natural product discovery

(2013) Ramesh Subramani et al.   APPLIED MICROBIOLOGY AND BIOTECHNOLOGY

Comparative genomics of actinomycetes with a focus on natural product biosynthetic genes

(2013) James R Doroghazi et al.   BMC GENOMICS

Metabolic potential of endophytic bacteria

(2013) Günter Brader et al.   CURRENT OPINION IN BIOTECHNOLOGY

Assembling Single-Cell Genomes and Mini-Metagenomes From Chimeric MDA Products

(2013) Sergey Nurk et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Challenges and triumphs to genomics-based natural product discovery

(2013) Paul R. Jensen et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Microbial genome mining for accelerated natural products discovery: is a renaissance in the making?

(2013) Brian O. Bachmann et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

Sponge-Derived Kocuria and Micrococcus spp. as Sources of the New Thiazolyl Peptide Antibiotic Kocurin

(2013) Sara Palomo et al.   Marine Drugs

Pharmaceutically active secondary metabolites of marine actinobacteria

(2013) Panchanathan Manivasagan et al.   MICROBIOLOGICAL RESEARCH

Detecting Sequence Homology at the Gene Cluster Level with MultiGeneBlast

(2013) Marnix H. Medema et al.   MOLECULAR BIOLOGY AND EVOLUTION

Erratum: Thoughts and facts about antibiotics: Where we are now and where we are heading

(2012) János Bérdy   JOURNAL OF ANTIBIOTICS

SPAdes: A New Genome Assembly Algorithm and Its Applications to Single-Cell Sequencing

(2012) Anton Bankevich et al.   JOURNAL OF COMPUTATIONAL BIOLOGY

Isolation, Characterization, and Bioactivity Evaluation of 3-((6-Methylpyrazin-2-yl)methyl)-1H-indole, a New Alkaloid from a Deep-Sea-Derived Actinomycete Serinicoccus profundi sp. nov.

(2012) Xian-Wen Yang et al.   Marine Drugs

The Natural Product Domain Seeker NaPDoS: A Phylogeny Based Bioinformatic Tool to Classify Secondary Metabolite Gene Diversity

(2012) Nadine Ziemert et al.   PLoS One

Exploration and Mining of the Bacterial Terpenome

(2011) David E. Cane et al.   ACCOUNTS OF CHEMICAL RESEARCH

Rare actinomycetes: a potential storehouse for novel antibiotics

(2011) Kavita Tiwari et al.   CRITICAL REVIEWS IN BIOTECHNOLOGY

Draft Genome Sequence of the Marine Sediment-Derived Actinomycete Streptomyces xinghaiensis NRRL B24674T

(2011) X. Zhao et al.   JOURNAL OF BACTERIOLOGY

Marine actinomycetes as an emerging resource for the drug development pipelines

(2011) Sergey B. Zotchev   JOURNAL OF BIOTECHNOLOGY

An integrated semiconductor device enabling non-optical genome sequencing

(2011) Jonathan M. Rothberg et al.   NATURE

Sequence-Based Analysis of Secondary-Metabolite Biosynthesis in Marine Actinobacteria

(2010) E. A. Gontang et al.   APPLIED AND ENVIRONMENTAL MICROBIOLOGY

The Discovery of Salinosporamide K from the Marine Bacterium “Salinispora pacifica” by Genome Mining Gives Insight into Pathway Evolution

(2010) Alessandra S. Eustáquio et al.   CHEMBIOCHEM

A consistent terminology for quantifying species diversity? Yes, it does exist

(2010) Hanna Tuomisto   OECOLOGIA

Dermacozines, a new phenazine family from deep-sea dermacocci isolated from a Mariana Trench sediment

(2010) Wael M. Abdel-Mageed et al.   ORGANIC & BIOMOLECULAR CHEMISTRY

trimAl: a tool for automated alignment trimming in large-scale phylogenetic analyses

(2009) S. Capella-Gutierrez et al.   BIOINFORMATICS

Circos: An information aesthetic for comparative genomics

(2009) M. Krzywinski et al.   GENOME RESEARCH

Genomic basis for natural product biosynthetic diversity in the actinomycetes

(2009) Markus Nett et al.   NATURAL PRODUCT REPORTS