Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism
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Title
Rifamycin congeners kanglemycins are active against rifampicin-resistant bacteria via a distinct mechanism
Authors
Keywords
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Journal
Nature Communications
Volume 9, Issue 1, Pages -
Publisher
Springer Nature America, Inc
Online
2018-10-02
DOI
10.1038/s41467-018-06587-2
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- (2017) Wei Lin et al. MOLECULAR CELL
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- (2015) Zachary Charlop-Powers et al. eLife
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- (2015) Alimuddin Zumla et al. Lancet Global Health
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- (2014) Beth P Goldstein JOURNAL OF ANTIBIOTICS
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- (2014) Elizabeth Davis et al. NUCLEIC ACIDS RESEARCH
- PCR screening reveals considerable unexploited biosynthetic potential of ansamycins and a mysterious family of AHBA-containing natural products in actinomycetes
- (2013) H.-X. Wang et al. JOURNAL OF APPLIED MICROBIOLOGY
- Engineering the acyltransferase substrate specificity of assembly line polyketide synthases
- (2013) B. J. Dunn et al. Journal of the Royal Society Interface
- Mapping gene clusters within arrayed metagenomic libraries to expand the structural diversity of biomedically relevant natural products
- (2013) J. G. Owen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2011) G.J. Everest et al. JOURNAL OF APPLIED MICROBIOLOGY
- Chaxamycins A–D, Bioactive Ansamycins from a Hyper-arid DesertStreptomycessp.
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- PHENIX: a comprehensive Python-based system for macromolecular structure solution
- (2010) Paul D. Adams et al. ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY
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- The Structural Diversity of Acidic Lipopeptide Antibiotics
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- PCR screening of 3-amino-5-hydroxybenzoic acid synthase gene leads to identification of ansamycins and AHBA-related antibiotic producers in Actinomycetes
- (2009) Z. Huitu et al. JOURNAL OF APPLIED MICROBIOLOGY
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- (2008) A. Feklistov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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