Genomic discovery of an evolutionarily programmed modality for small-molecule targeting of an intractable protein surface

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

(2020) David E. Gordon et al.   NATURE

The trimeric coiled‐coil HSBP1 protein promotes WASH complex assembly at centrosomes

(2018) Sai P Visweshwaran et al.   EMBO JOURNAL

Rule of five in 2015 and beyond: Target and ligand structural limitations, ligand chemistry structure and drug discovery project decisions

(2016) Christopher A. Lipinski   ADVANCED DRUG DELIVERY REVIEWS

Natural product discovery: past, present, and future

(2016) Leonard Katz et al.   JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY

The Centrosomal Linker and Microtubules Provide Dual Levels of Spatial Coordination of Centrosomes

(2015) Marko Panic et al.   PLoS Genetics

Structural basis of conformational transitions in the active site and 80′s loop in the FK506-binding protein FKBP12

(2014) Sourajit M. Mustafi et al.   BIOCHEMICAL JOURNAL

Multisite phosphorylation of C-Nap1 releases it from Cep135 to trigger centrosome disjunction

(2014) T. Hardy et al.   JOURNAL OF CELL SCIENCE

EGF-Induced Centrosome Separation Promotes Mitotic Progression and Cell Survival

(2013) Balca R. Mardin et al.   DEVELOPMENTAL CELL

Large FK506-Binding Proteins Shape the Pharmacology of Rapamycin

(2013) A. M. Marz et al.   MOLECULAR AND CELLULAR BIOLOGY

Breaking the ties that bind: New advances in centrosome biology

(2012) Balca R. Mardin et al.   JOURNAL OF CELL BIOLOGY

Natural Products As Sources of New Drugs over the 30 Years from 1981 to 2010

(2012) David J. Newman et al.   JOURNAL OF NATURAL PRODUCTS

Timing of centrosome separation is important for accurate chromosome segregation

(2011) William T. Silkworth et al.   MOLECULAR BIOLOGY OF THE CELL

Identifying druggable disease-modifying gene products

(2009) Scott J Dixon et al.   CURRENT OPINION IN CHEMICAL BIOLOGY

Estimating the size of the human interactome

(2008) M. P. H. Stumpf et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA