Therapeutic Potential of Natural Products in Treating Neurodegenerative Disorders and Their Future Prospects and Challenges

The Role of Natural Antioxidants in the Prevention of Dementia—Where Do We Stand and Future Perspectives

(2021) Anamaria Jurcau   Nutrients

Redox Effects of Molecular Hydrogen and Its Therapeutic Efficacy in the Treatment of Neurodegenerative Diseases

(2021) Md. Habibur Rahman et al.   Processes

Natural Products and Their Bioactive Compounds: Neuroprotective Potentials against Neurodegenerative Diseases

(2020) Nur Shafika Mohd Sairazi et al.   Evidence-based Complementary and Alternative Medicine

Recent advances in self-assembled nanoparticles for drug delivery

(2020) Lanke Tejesh Verma et al.   Current Drug Delivery

The complete chloroplast genome of the traditional Chinese herb, Uncaria rhynchophylla (Rubiaceae)

(2020) Li-Zhen Ling et al.   Mitochondrial DNA Part B-Resources

Neuroprotective Effects of Quercetin in Alzheimer’s Disease

(2020) Haroon Khan et al.   Biomolecules

The necroptosis pathway and its role in age-related neurodegenerative diseases: will it open up new therapeutic avenues in the next decade?

(2020) Natalia Salvadores et al.   EXPERT OPINION ON THERAPEUTIC TARGETS

The Pharmacological Activity, Biochemical Properties, and Pharmacokinetics of the Major Natural Polyphenolic Flavonoid: Quercetin

(2020) Gaber El-Saber Batiha et al.   Foods

Prospective Function of Different Antioxidant Containing Natural Products in the Treatment of Neurodegenerative Disease

(2020) Md. Habibur Rahman et al.   CNS & Neurological Disorders-Drug Targets

Brain‐targeted co‐delivery of β‐amyloid converting enzyme 1 shRNA and epigallocatechin‐3‐gallate by multifunctional nanocarriers for Alzheimer's disease treatment

(2020) Lijie Lv et al.   IUBMB LIFE

Neuroprotective Potentials of Marine Algae and Their Bioactive Metabolites: Pharmacological Insights and Therapeutic Advances

(2020) Md. Abdul Hannan et al.   Marine Drugs

Exploring the multimodal role of phytochemicals in the modulation of cellular signaling pathways to combat age-related neurodegeneration

(2020) Md. Sahab Uddin et al.   SCIENCE OF THE TOTAL ENVIRONMENT

Cancer cells with defective oxidative phosphorylation require endoplasmic reticulum–to–mitochondria Ca2+ transfer for survival

(2020) Cesar Cardenas et al.   Science Signaling

SIRT1 Activation by Natural Phytochemicals: An Overview

(2020) Concetta Iside et al.   Frontiers in Pharmacology

Neuroprotection: Targeting Multiple Pathways by Naturally Occurring Phytochemicals

(2020) Andleeb Khan et al.   Biomedicines

Transport and metabolic profiling studies of amentoflavone in Caco-2 cells by UHPLC-ESI-MS/MS and UHPLC-ESI-Q-TOF-MS/MS

(2020) Baolin Wang et al.   JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS

On the Right Track to Treat Movement Disorders: Promising Therapeutic Approaches for Parkinson’s and Huntington’s Disease

(2020) Paulina Troncoso-Escudero et al.   Frontiers in Aging Neuroscience

Behavioral, axonal, and proteomic alterations following repeated mild traumatic brain injury: Novel insights using a clinically relevant rat model

(2020) Louise Pham et al.   NEUROBIOLOGY OF DISEASE

Resveratrol and Neuroprotection: Impact and Its Therapeutic Potential in Alzheimer's Disease

(2020) Md. Habibur Rahman et al.   Frontiers in Pharmacology

Flavonoids and Polyphenolic Compounds as Potential Talented Agents for the Treatment of Alzheimer’s Disease and their Antioxidant Activities

(2020) Rokeya Akter et al.   CURRENT PHARMACEUTICAL DESIGN

A critical review on grape polyphenols for neuroprotection: Strategies to enhance bioefficacy

(2019) Danyue Zhao et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Roles of Phenolic Compounds in the Reduction of Risk Factors of Cardiovascular Diseases

(2019) Mariane Lutz et al.   MOLECULES

Hesperidin as a Neuroprotective Agent: A Review of Animal and Clinical Evidence

(2019) Marziyeh Hajialyani et al.   MOLECULES

Safflower yellow attenuates learning and memory deficits in amyloid β-induced Alzheimer’s disease rats by inhibiting neuroglia cell activation and inflammatory signaling pathways

(2019) Lu Zhang et al.   METABOLIC BRAIN DISEASE

Evidence on Integrating Pharmacokinetics to Find Truly Therapeutic Agent for Alzheimer’s Disease: Comparative Pharmacokinetics and Disposition Kinetics Profiles of Stereoisomers Isorhynchophylline and Rhynchophylline in Rats

(2019) Chunyuan Zhang et al.   Evidence-based Complementary and Alternative Medicine

Resveratrol alleviates lipopolysaccharide-induced inflammation in PC-12 cells and in rat model

(2019) Guiqi Zhang et al.   BMC BIOTECHNOLOGY

Neuroprotective Effects of Anthraquinones from Rhubarb in Central Nervous System Diseases

(2019) Xun Li et al.   Evidence-based Complementary and Alternative Medicine

Antioxidant and Photoprotective Activity of Apigenin and its Potassium Salt Derivative in Human Keratinocytes and Absorption in Caco-2 Cell Monolayers

(2019) Sánchez-Marzo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Considerations for the Use of Polyphenols as Therapies in Neurodegenerative Diseases

(2019) Justine Renaud et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Marine-Derived Natural Compounds for the Treatment of Parkinson’s Disease

(2019) Chunhui Huang et al.   Marine Drugs

Oxidative Stress: A Key Modulator in Neurodegenerative Diseases

(2019) Anju Singh et al.   MOLECULES

Natural Antioxidant Anthocyanins—A Hidden Therapeutic Candidate in Metabolic Disorders with Major Focus in Neurodegeneration

(2019) Ullah et al.   Nutrients

Brown Rice Versus White Rice: Nutritional Quality, Potential Health Benefits, Development of Food Products, and Preservation Technologies

(2019) Ahmed S. M. Saleh et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Natural Products as Potential anti-Alzheimer Agents

(2019) Siva S Panda et al.   CURRENT MEDICINAL CHEMISTRY

Uncaria rhynchophylla and Its Major Constituents on Central Nervous System: A Review on Their Pharmacological Actions

(2019) Wen Yang et al.   Current Vascular Pharmacology

The roles of Flavonoles/Flavonoids in Neurodegeneration and Neuroinflammation

(2019) Zehra Calis et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

Lewy pathology in Parkinson’s disease consists of crowded organelles and lipid membranes

(2019) Sarah H. Shahmoradian et al.   NATURE NEUROSCIENCE

Polyphenols: A concise overview on the chemistry, occurrence, and human health

(2019) Alessandra Durazzo et al.   PHYTOTHERAPY RESEARCH

Agaropentaose protects SH-SY5Y cells against 6-hydroxydopamine-induced neurotoxicity through modulating NF-κB and p38MAPK signaling pathways

(2019) Qiang Ye et al.   Journal of Functional Foods

Role of Dietary Supplements in the Management of Parkinson’s Disease

(2019) Michele Ciulla et al.   Biomolecules

An Update on Pharmacological Potential of Boswellic Acids against Chronic Diseases

(2019) Nand Kishor Roy et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

A Novel Quinolyl‐Substituted Analogue of Resveratrol Inhibits LPS‐Induced Inflammatory Responses in Microglial Cells by Blocking the NF‐κB/MAPK Signaling Pathways

(2019) Yue Hou et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Manganese-Induced Neurotoxicity: New Insights Into the Triad of Protein Misfolding, Mitochondrial Impairment, and Neuroinflammation

(2019) Dilshan S. Harischandra et al.   Frontiers in Neuroscience

A Study for Therapeutic Treatment against Parkinson’s Disease via Chou’s 5-steps Rule

(2019) Jianqiang Lan et al.   CURRENT TOPICS IN MEDICINAL CHEMISTRY

Natural Products in Neurodegenerative Diseases: A Great Promise but an Ethical Challenge

(2019) Marco Di Paolo et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Natural Products and Neuroprotection

(2019) Cristina Angeloni et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Marine Polysaccharides in Pharmaceutical Applications: Fucoidan and Chitosan as Key Players in the Drug Delivery Match Field

(2019) Ana Isabel Barbosa et al.   Marine Drugs

Glucagon-Like Peptide-1: A Focus on Neurodegenerative Diseases

(2019) Maddalena Grieco et al.   Frontiers in Neuroscience

Diabetes mellitus and Alzheimer’s disease: GSK-3β as a potential link

(2018) Ying Zhang et al.   BEHAVIOURAL BRAIN RESEARCH

Resveratrol promotes neuroprotection and attenuates oxidative and nitrosative stress in the small intestine in diabetic rats

(2018) Paulo Emilio Botura Ferreira et al.   BIOMEDICINE & PHARMACOTHERAPY

The antioxidant and neurochemical activity of Apium graveolens L. and its ameliorative effect on MPTP-induced Parkinson-like symptoms in mice

(2018) Pennapa Chonpathompikunlert et al.   BMC Complementary and Alternative Medicine

Neuroprotective effects of seaweeds against 6-hydroxidopamine-induced cell death on an in vitro human neuroblastoma model

(2018) Joana Silva et al.   BMC Complementary and Alternative Medicine

Uncaria rhynchophylla Ameliorates Parkinson’s Disease by Inhibiting HSP90 Expression: Insights from Quantitative Proteomics

(2018) Yu-Long Lan et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

The Bioavailability, Transport, and Bioactivity of Dietary Flavonoids: A Review from a Historical Perspective

(2018) Gary Williamson et al.   COMPREHENSIVE REVIEWS IN FOOD SCIENCE AND FOOD SAFETY

Mitochondrial Dysfunction in Parkinson’s Disease: New Mechanistic Insights and Therapeutic Perspectives

(2018) Jin-Sung Park et al.   Current Neurology and Neuroscience Reports

Diet and Brain Health: Which Role for Polyphenols?

(2018) Vanessa Castelli et al.   CURRENT PHARMACEUTICAL DESIGN

Inflammation in CNS neurodegenerative diseases

(2018) Jodie Stephenson et al.   IMMUNOLOGY

Marine macroalgae as sources of protein and bioactive compounds in feed for monogastric animals

(2018) Margareth Øverland et al.   JOURNAL OF THE SCIENCE OF FOOD AND AGRICULTURE

Taxifolin prevents β-amyloid-induced impairments of synaptic formation and deficits of memory via the inhibition of cytosolic phospholipase A2/prostaglandin E2 content

(2018) Yuanyuan Wang et al.   METABOLIC BRAIN DISEASE

The basal ganglia and the cerebellum: nodes in an integrated network

(2018) Andreea C. Bostan et al.   NATURE REVIEWS NEUROSCIENCE

Use of curcumin in diagnosis, prevention, and treatment of Alzheimer's disease

(2018) Kun Zhang et al.   Neural Regeneration Research

Microglia in the Neurovascular Unit: Blood–Brain Barrier–microglia Interactions After Central Nervous System Disorders

(2018) Hannah Thurgur et al.   NEUROSCIENCE

Metabolic Enhancer Piracetam Attenuates the Translocation of Mitochondrion-Specific Proteins of Caspase-Independent Pathway, Poly [ADP-Ribose] Polymerase 1 Up-regulation and Oxidative DNA Fragmentation

(2018) Dinesh Kumar Verma et al.   NEUROTOXICITY RESEARCH

Apigenin as neuroprotective agent: Of mice and men

(2018) Seyed Fazel Nabavi et al.   PHARMACOLOGICAL RESEARCH

Ameliorative effects of Matricaria chamomilla L. hydroalcoholic extract on scopolamine-induced memory impairment in rats: A behavioral and molecular study

(2018) Radu Ionita et al.   PHYTOMEDICINE

Linking Neuroinflammation and Neurodegeneration in Parkinson’s Disease

(2018) Géraldine Gelders et al.   Journal of Immunology Research

Neuroinflammation: Microglia and T Cells Get Ready to Tango

(2018) Sjoerd T. T. Schetters et al.   Frontiers in Immunology

Neuroprotective Strategies for Neurological Disorders by Natural Products: An update

(2018) Muneeb U Rehman et al.   Current Neuropharmacology

Improvement of Main Cognitive Functions in Patients with Alzheimer’s Disease after Treatment with Coconut Oil Enriched Mediterranean Diet: A Pilot Study

(2018) José Enrique de la Rubia Ortí et al.   JOURNAL OF ALZHEIMERS DISEASE

An ethnobotanical survey and inhibitory effects on NLRP3 inflammasomes/Caspase-1 of herbal recipes’ extracts traditionally used in Rwanda for asthma treatment

(2018) Jean Claude Didelot Tomani et al.   JOURNAL OF ETHNOPHARMACOLOGY

Quercetin in Food: Possible Mechanisms of Its Effect on Memory

(2018) Fatemeh Babaei et al.   JOURNAL OF FOOD SCIENCE

Selective vulnerability in neurodegenerative diseases

(2018) Hongjun Fu et al.   NATURE NEUROSCIENCE

Converging pathways in neurodegeneration, from genetics to mechanisms

(2018) Li Gan et al.   NATURE NEUROSCIENCE

2,3,5,4′-Tetrahydroxystilbene-2-O-beta-D-glucoside Reverses Stress-Induced Depression via Inflammatory and Oxidative Stress Pathways

(2018) Cheng-Yong Jiang et al.   Oxidative Medicine and Cellular Longevity

Yacon leaf extract supplementation demonstrates neuroprotective effect against memory deficit related to β-amyloid-induced neurotoxicity

(2018) Patrícia Martinez-Oliveira et al.   Journal of Functional Foods

Fucoidan Protects Dopaminergic Neurons by Enhancing the Mitochondrial Function in a Rotenone-induced Rat Model of Parkinson’s Disease

(2018) Li Zhang et al.   Aging and Disease

Effect of Fermented Spirulina maxima Extract on Cognitive-Enhancing Activities in Mice with Scopolamine-Induced Dementia

(2018) Woon Yong Choi et al.   Evidence-based Complementary and Alternative Medicine

Conformational deviation of Thrombin binding G-quadruplex aptamer (TBA) in presence of divalent cation Sr2+: A classical molecular dynamics simulation study

(2018) Saikat Pal et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Phytochemical constituents from Uncaria rhynchophylla in human carboxylesterase 2 inhibition: Kinetics and interaction mechanism merged with docking simulations

(2018) Ya-Li Wang et al.   PHYTOMEDICINE

Neuroprotective Effects of Ethyl Acetate Extract of Zingiber zerumbet (L.) Smith against Oxidative Stress on Paraquat-Induced Parkinsonism in Rats

(2018) Farah Washida Ibrahim et al.   Sains Malaysiana

Microglia in Central Nervous System Inflammation and Multiple Sclerosis Pathology

(2018) Sofie Voet et al.   TRENDS IN MOLECULAR MEDICINE

Phyto-Therapeutic and Nanomedicinal Approaches to Cure Alzheimer’s Disease: Present Status and Future Opportunities

(2018) Muhammad Ovais et al.   Frontiers in Aging Neuroscience

Herbal Medicine Formulas for Parkinson's Disease: A Systematic Review and Meta-Analysis of Randomized Double-Blind Placebo-Controlled Clinical Trials

(2018) Chun-Shuo Shan et al.   Frontiers in Aging Neuroscience

Insights into GABA A ergic system alteration in Huntington's disease

(2018) Yi-Ting Hsu et al.   Open Biology

Nanocarriers as a powerful vehicle to overcome blood-brain barrier in treating neurodegenerative diseases: Focus on recent advances

(2018) Xiaoqian Niu et al.   Asian Journal of Pharmaceutical Sciences

Resveratrol: A miraculous natural compound for diseases treatment

(2018) Mehdi Koushki et al.   Food Science & Nutrition

Spirulina maxima Extract Ameliorates Learning and Memory Impairments via Inhibiting GSK-3β Phosphorylation Induced by Intracerebroventricular Injection of Amyloid-β 1–42 in Mice

(2017) Eun-Jeong Koh et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Resveratrol Intervenes Cholesterol- and Isoprenoid-Mediated Amyloidogenic Processing of AβPP in Familial Alzheimer’s Disease

(2017) Mohan Sathya et al.   JOURNAL OF ALZHEIMERS DISEASE

Resveratrol regulates neuro-inflammation and induces adaptive immunity in Alzheimer’s disease

(2017) Charbel Moussa et al.   Journal of Neuroinflammation

Protective Effects of Fucoidan on Aβ25–35 and d-Gal-Induced Neurotoxicity in PC12 Cells and d-Gal-Induced Cognitive Dysfunction in Mice

(2017) Hengyun Wei et al.   Marine Drugs

Anti-Inflammatory and Neuroprotective Role of Natural Product Securinine in Activated Glial Cells: Implications for Parkinson’s Disease

(2017) Dmitri Leonoudakis et al.   MEDIATORS OF INFLAMMATION

The neuroprotective effects of hydro-alcoholic extract of olive (Olea europaea L.) leaf on rotenone-induced Parkinson’s disease in rat

(2017) Maryam Sarbishegi et al.   METABOLIC BRAIN DISEASE

Dopamine and Levodopa Prodrugs for the Treatment of Parkinson’s Disease

(2017) et al.   MOLECULES

The Blood-Brain Barrier Permeability of Six Indole Alkaloids from Uncariae Ramulus Cum Uncis in the MDCK-pHaMDR Cell Monolayer Model

(2017) Yi-Nan Zhang et al.   MOLECULES

The Role of Metal Binding in the Amyotrophic Lateral Sclerosis-Related Aggregation of Copper-Zinc Superoxide Dismutase

(2017) et al.   MOLECULES

Spirulina maxima Extract Prevents Neurotoxicity via Promoting Activation of BDNF/CREB Signaling Pathways in Neuronal Cells and Mice

(2017) Eun-Jeong Koh et al.   MOLECULES

Past, present, and future of Parkinson's disease: A special essay on the 200th Anniversary of the Shaking Palsy

(2017) J.A. Obeso et al.   MOVEMENT DISORDERS

Neuroprotective effect of omega-3 polyunsaturated fatty acids in the 6-OHDA model of Parkinson's disease is mediated by a reduction of inducible nitric oxide synthase

(2017) Marco Aurélio Mori et al.   NUTRITIONAL NEUROSCIENCE

Apigenin in cancer therapy: anti-cancer effects and mechanisms of action

(2017) Xiaohui Yan et al.   Cell and Bioscience

Uncovering Potential Applications of Cyanobacteria and Algal Metabolites in Biology, Agriculture and Medicine: Current Status and Future Prospects

(2017) Rachana Singh et al.   Frontiers in Microbiology

Huntingtin gene repeat size variations affect risk of lifetime depression

(2017) Sarah L. Gardiner et al.   Translational Psychiatry

Parkinson disease

(2017) Werner Poewe et al.   Nature Reviews Disease Primers

Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy

(2017) Satoshi Saito et al.   Acta Neuropathologica Communications

Dihydromyricetin protects neurons in an MPTP-induced model of Parkinson's disease by suppressing glycogen synthase kinase-3 beta activity

(2016) Zhao-xiang Ren et al.   ACTA PHARMACOLOGICA SINICA

Inflammatory Mechanisms and Oxidative Stress as Key Factors Responsible for Progression of Neurodegeneration: Role of Brain Innate Immune System

(2016) Jerzy Leszek et al.   CNS & Neurological Disorders-Drug Targets

Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment

(2016) Mojtaba Golpich et al.   CNS Neuroscience & Therapeutics

DLS and zeta potential – What they are and what they are not?

(2016) Sourav Bhattacharjee   JOURNAL OF CONTROLLED RELEASE

Sulfated Seaweed Polysaccharides as Multifunctional Materials in Drug Delivery Applications

(2016) Ludmylla Cunha et al.   Marine Drugs

β-Caryophyllene, a phytocannabinoid attenuates oxidative stress, neuroinflammation, glial activation, and salvages dopaminergic neurons in a rat model of Parkinson disease

(2016) Shreesh Ojha et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Antioxidant-Rich Fraction of Urtica dioica Mediated Rescue of Striatal Mito-Oxidative Damage in MPTP-Induced Behavioral, Cellular, and Neurochemical Alterations in Rats

(2016) Rohit Bisht et al.   MOLECULAR NEUROBIOLOGY

Detection of 191 Taxifolin Metabolites and Their Distribution in Rats Using HPLC-ESI-IT-TOF-MSn

(2016) Ping Yang et al.   MOLECULES

Hesperidin ameliorates cognitive dysfunction, oxidative stress and apoptosis against aluminium chloride induced rat model of Alzheimer's disease

(2016) Arokiasamy Justin Thenmozhi et al.   NUTRITIONAL NEUROSCIENCE

Mechanisms of Neuroprotection by Quercetin: Counteracting Oxidative Stress and More

(2016) Lucio G. Costa et al.   Oxidative Medicine and Cellular Longevity

The Role of the Reactive Oxygen Species and Oxidative Stress in the Pathomechanism of the Age-Related Ocular Diseases and Other Pathologies of the Anterior and Posterior Eye Segments in Adults

(2016) Małgorzata Nita et al.   Oxidative Medicine and Cellular Longevity

Nrf2–ARE pathway: An emerging target against oxidative stress and neuroinflammation in neurodegenerative diseases

(2016) Izaskun Buendia et al.   PHARMACOLOGY & THERAPEUTICS

Improved delivery of poorly soluble compounds using nanoparticle technology: a review

(2016) Sandeep Kalepu et al.   Drug Delivery and Translational Research

Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer’s disease

(2016) Rachelle Balez et al.   Scientific Reports

Neuroprotective action of resveratrol

(2015) Stéphane Bastianetto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Bioactivity of genistein: A review of in vitro and in vivo studies

(2015) Ajaz Ahmad Ganai et al.   BIOMEDICINE & PHARMACOTHERAPY

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

(2015) Aashiq Hussain Bhat et al.   BIOMEDICINE & PHARMACOTHERAPY

The preclinical phase of the pathological process underlying sporadic Alzheimer’s disease

(2015) Heiko Braak et al.   BRAIN

Luteolin as an anti-inflammatory and neuroprotective agent: A brief review

(2015) Seyed Fazel Nabavi et al.   BRAIN RESEARCH BULLETIN

Germinated Brown Rice Alters Aβ(1-42) Aggregation and Modulates Alzheimer’s Disease-Related Genes in Differentiated Human SH-SY5Y Cells

(2015) Nur Hanisah Azmi et al.   Evidence-based Complementary and Alternative Medicine

Clinical development of curcumin in neurodegenerative disease

(2015) Shuxin Hu et al.   Expert Review of Neurotherapeutics

Metal-deficient SOD1 in amyotrophic lateral sclerosis

(2015) James B. Hilton et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Proteostasis and aging

(2015) Susmita Kaushik et al.   NATURE MEDICINE

Protective effects of a polysaccharide from Spirulina platensis on dopaminergic neurons in an MPTP-induced Parkinson′s disease model in C57BL/6J mice

(2015) Fang Zhang et al.   Neural Regeneration Research

Resveratrol neuroprotection in stroke and traumatic CNS injury

(2015) Mary S. Lopez et al.   NEUROCHEMISTRY INTERNATIONAL

A randomized, double-blind, placebo-controlled trial of resveratrol for Alzheimer disease

(2015) R. Scott Turner et al.   NEUROLOGY

Hesperidin inhibits glutamate release and exerts neuroprotection against excitotoxicity induced by kainic acid in the hippocampus of rats

(2015) Chia Ying Chang et al.   NEUROTOXICOLOGY

Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP5+, Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma Multiforme

(2015) Yulyana Yulyana et al.   Stem Cell Reviews and Reports

Impaired intracellular trafficking defines early Parkinson's disease

(2015) Benjamin H.M. Hunn et al.   TRENDS IN NEUROSCIENCES

Enhancement of flavonoid ability to cross the blood–brain barrier of rats by co-administration with α-tocopherol

(2015) Paola Ferri et al.   Food & Function

Osmotin attenuates amyloid beta-induced memory impairment, tau phosphorylation and neurodegeneration in the mouse hippocampus

(2015) Tahir Ali et al.   Scientific Reports

Clinical development of curcumin in neurodegenerative disease

(2015) Shuxin Hu et al.   Expert Review of Neurotherapeutics

Redox-Active Mn Porphyrin-based Potent SOD Mimic, MnTnBuOE-2-PyP5+, Enhances Carbenoxolone-Mediated TRAIL-Induced Apoptosis in Glioblastoma Multiforme

(2015) Yulyana Yulyana et al.   Stem Cell Reviews and Reports

Mitochondrial Dysfunction in Parkinson's Disease

(2015) Hyo Eun Moon et al.   Experimental Neurobiology

Dietary Polyphenols for Treatment of Alzheimer’s Disease– Future Research and Development

(2014) D. Malar et al.   CURRENT PHARMACEUTICAL BIOTECHNOLOGY

Development, characterization and nasal delivery of rosmarinic acid-loaded solid lipid nanoparticles for the effective management of Huntington’s disease

(2014) Rahul Bhatt et al.   DRUG DELIVERY

Nutraceuticals and amyloid neurodegenerative diseases: a focus on natural phenols

(2014) Stefania Rigacci et al.   Expert Review of Neurotherapeutics

Hesperidin potentiates the neuroprotective effects of diazepam and gabapentin against pentylenetetrazole-induced convulsions in mice: Possible behavioral, biochemical and mitochondrial alterations

(2014) Anil Kumar et al.   INDIAN JOURNAL OF PHARMACOLOGY

Neuroprotective effect of Tinospora cordifolia ethanol extract on 6-hydroxy dopamine induced Parkinsonism

(2014) Jayasankar Kosaraju et al.   INDIAN JOURNAL OF PHARMACOLOGY

Common mechanisms in neurodegeneration and neuroinflammation: a BrainNet Europe gene expression microarray study

(2014) Pascal F. Durrenberger et al.   JOURNAL OF NEURAL TRANSMISSION

Exploring Marine Resources for Bioactive Compounds

(2014) Paula Kiuru et al.   PLANTA MEDICA

Resveratrol encapsulation: Designing delivery systems to overcome solubility, stability and bioavailability issues

(2014) Gabriel Davidov-Pardo et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Functional ingredients from microalgae

(2014) Silvia Buono et al.   Food & Function

Resveratrol as a Therapeutic Agent for Alzheimer’s Disease

(2014) Teng Ma et al.   Biomed Research International

Mitochondrial permeability transition pore is a potential drug target for neurodegeneration

(2013) Valasani Koteswara Rao et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondria and Quality Control Defects in a Mouse Model of Gaucher Disease—Links to Parkinson’s Disease

(2013) Laura D. Osellame et al.   Cell Metabolism

Acetylcholinesterase Inhibitors: Pharmacology and Toxicology

(2013) Mirjana B. Colovic et al.   Current Neuropharmacology

The flavonoid apigenin delays forgetting of passive avoidance conditioning in rats

(2013) Miroljub Popović et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Functional effect of Saffron supplementation and risk genotypes in early age-related macular degeneration: a preliminary report

(2013) Dario Marangoni et al.   Journal of Translational Medicine

Beneficial Effects of Marine Algal Compounds in Cosmeceuticals

(2013) Noel Thomas et al.   Marine Drugs

High dose genistein aglycone therapy is safe in patients with mucopolysaccharidoses involving the central nervous system

(2013) Katherine H. Kim et al.   MOLECULAR GENETICS AND METABOLISM

Polyphenols: Multipotent Therapeutic Agents in Neurodegenerative Diseases

(2013) Khushwant S. Bhullar et al.   Oxidative Medicine and Cellular Longevity

Advances in the pharmacological treatment of Parkinson's disease: targeting neurotransmitter systems

(2013) Lars Brichta et al.   TRENDS IN NEUROSCIENCES

Interactions between Phytochemicals from Traditional Chinese Medicines and Human Cytochrome P450 Enzymes

(2012) Jing-Jing Wu et al.   CURRENT DRUG METABOLISM

Bioassay-Guided Isolation of Neuroprotective Compounds fromUncaria rhynchophyllaagainst Beta-Amyloid-Induced Neurotoxicity

(2012) Yan-Fang Xian et al.   Evidence-based Complementary and Alternative Medicine

The blood-brain barrier is disrupted in a mouse model of infantile neuronal ceroid lipofuscinosis: amelioration by resveratrol

(2012) Arjun Saha et al.   HUMAN MOLECULAR GENETICS

Naturally derived anti-inflammatory compounds from Chinese medicinal plants

(2012) Qiuhong Wang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Gender Disparities in Health Care

(2012) Jennifer A. Kent et al.   MOUNT SINAI JOURNAL OF MEDICINE

Accumulation of orally administered quercetin in brain tissue and its antioxidative effects in rats

(2011) Akari Ishisaka et al.   FREE RADICAL BIOLOGY AND MEDICINE

In vitro–in vivo correlation: Perspectives on model development

(2011) Ying Lu et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Nanolipidic particles improve the bioavailability and α-secretase inducing ability of epigallocatechin-3-gallate (EGCG) for the treatment of Alzheimer's disease

(2010) Adam Smith et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Genistein ameliorates learning and memory deficits in amyloid β(1–40) rat model of Alzheimer’s disease

(2010) Maryam Bagheri et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Alteration of the nuclear pore complex in Ca2+-mediated cell death

(2009) D Bano et al.   CELL DEATH AND DIFFERENTIATION

Effects of the hook of Uncaria rhynchophylla on neurotoxicity in the 6-hydroxydopamine model of Parkinson's disease

(2009) Jin Sup Shim et al.   JOURNAL OF ETHNOPHARMACOLOGY

Mechanisms of neurodegeneration in Huntington’s disease

(2008) Joana M. Gil et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Positive modulation of cognition and mood in the healthy elderly volunteer following the administration of Centella asiatica

(2007) Jintanaporn Wattanathorn et al.   JOURNAL OF ETHNOPHARMACOLOGY