An Update on Pharmacological Potential of Boswellic Acids against Chronic Diseases

Signal Transducer and Activator of Transcription (STATs) Proteins in Cancer and Inflammation: Functions and Therapeutic Implication

(2019) Chin-Yap Loh et al.   Frontiers in Oncology

FBXW7 in Cancer: What Has Been Unraveled Thus Far?

(2019) Bethsebie Lalduhsaki Sailo et al.   Cancers

A pilot, randomized, double-blind, placebo-controlled trial to assess the safety and efficacy of a novel Boswellia serrata extract in the management of osteoarthritis of the knee

(2019) Muhammed Majeed et al.   PHYTOTHERAPY RESEARCH

Role of Natural Products in Modulating Histone Deacetylases in Cancer

(2019) Myriam Merarchi et al.   MOLECULES

Pleiotropic Pharmacological Actions of Capsazepine, a Synthetic Analogue of Capsaicin, against Various Cancers and Inflammatory Diseases

(2019) Min Yang et al.   MOLECULES

Potential of Zerumbone as an Anti-Cancer Agent

(2019) Sosmitha Girisa et al.   MOLECULES

Targeting autophagy using natural compounds for cancer prevention and therapy

(2019) Shuo Deng et al.   CANCER

Biopharmacological considerations for accelerating drug development of deguelin, a rotenoid with potent chemotherapeutic and chemopreventive potential

(2019) Rahel Sarah Varughese et al.   CANCER

Cancer drug development: The missing links

(2019) Ajaikumar B Kunnumakkara et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Focus on Formononetin: Anticancer Potential and Molecular Targets

(2019) Ong et al.   Cancers

Honokiol for cancer therapeutics: A traditional medicine that can modulate multiple oncogenic targets

(2019) Kishore Banik et al.   PHARMACOLOGICAL RESEARCH

Inhibitory effect of 11-carbonyl-beta-boswellic acid on non-small cell lung cancer H446 cells

(2018) Gang Huang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Efficacy and safety of curcumin and its combination with boswellic acid in osteoarthritis: a comparative, randomized, double-blind, placebo-controlled study

(2018) Armine Haroyan et al.   BMC Complementary and Alternative Medicine

Therapeutic potential of gambogic acid, a caged xanthone, to target cancer

(2018) Kishore Banik et al.   CANCER LETTERS

Formononetin-induced oxidative stress abrogates the activation of STAT3/5 signaling axis and suppresses the tumor growth in multiple myeloma preclinical model

(2018) Chulwon Kim et al.   CANCER LETTERS

3-O-acetyl-11-keto-β-boswellic acid exerts anti-tumor effects in glioblastoma by arresting cell cycle at G2/M phase

(2018) Wan Li et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Chronic diseases, inflammation, and spices: how are they linked?

(2018) Ajaikumar B. Kunnumakkara et al.   Journal of Translational Medicine

Acetyl-11-keto-β-boswellic acid inhibits the secretion of cytokines by dendritic cells via the TLR7/8 pathway in an imiquimod-induced psoriasis mouse model and in vitro

(2018) Ming-Xing Wang et al.   LIFE SCIENCES

Protective Effect of Boswellic Acids against Doxorubicin-Induced Hepatotoxicity: Impact on Nrf2/HO-1 Defense Pathway

(2018) Bassant M. Barakat et al.   Oxidative Medicine and Cellular Longevity

Modulation of diverse oncogenic transcription factors by thymoquinone, an essential oil compound isolated from the seeds of Nigella sativa Linn

(2018) Muthu K. Shanmugam et al.   PHARMACOLOGICAL RESEARCH

Targeting activator protein 1 signaling pathway by bioactive natural agents: Possible therapeutic strategy for cancer prevention and intervention

(2018) Devesh Tewari et al.   PHARMACOLOGICAL RESEARCH

Tocotrienols: The promising analogues of vitamin E for cancer therapeutics

(2018) Bethsebie Lalduhsaki Sailo et al.   PHARMACOLOGICAL RESEARCH

Combined acetyl-11-keto-β-boswellic acid and radiation treatment inhibited glioblastoma tumor cells

(2018) Sefora Conti et al.   PLoS One

Pro-Apoptotic and Anti-Cancer Properties of Diosgenin: A Comprehensive and Critical Review

(2018) Gautam Sethi et al.   Nutrients

An Empirical Study of Chronic Diseases in the United States: A Visual Analytics Approach to Public Health

(2018) Wullianallur Raghupathi et al.   International Journal of Environmental Research and Public Health

Anti-myeloma Effects of Icariin Are Mediated Through the Attenuation of JAK/STAT3-Dependent Signaling Cascade

(2018) Young Yun Jung et al.   Frontiers in Pharmacology

Celastrol Attenuates the Invasion and Migration and Augments the Anticancer Effects of Bortezomib in a Xenograft Mouse Model of Multiple Myeloma

(2018) Muthu K. Shanmugam et al.   Frontiers in Pharmacology

Novel 1,3,4-Oxadiazole Induces Anticancer Activity by Targeting NF-κB in Hepatocellular Carcinoma Cells

(2018) Chakrabhavi Dhananjaya Mohan et al.   Frontiers in Oncology

Acetyl-11-keto-β-boswellic acid suppresses docetaxel-resistant prostate cancer cells in vitro and in vivo by blocking Akt and Stat3 signaling, thus suppressing chemoresistant stem cell-like properties

(2018) Yong-qing Liu et al.   ACTA PHARMACOLOGICA SINICA

Design, synthesis and biological evaluation of ring A modified 11-keto-boswellic acid derivatives as Pin1 inhibitors with remarkable anti-prostate cancer activity

(2018) Min Huang et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Chemoprevention of inflammation-related colorectal cancer by silymarin-, acetyl-11-keto-beta-boswellic acid-, curcumin- and maltodextrin-enriched dietetic formulation in animal model

(2018) Bruna Girardi et al.   CARCINOGENESIS

Magnolol: A Neolignan from the Magnolia Family for the Prevention and Treatment of Cancer

(2018) Abhishek Ranaware et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Acetyl-11-keto-β-boswellic acid ameliorates renal interstitial fibrosis via Klotho/TGF-β/Smad signalling pathway

(2018) Minna Liu et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Oleuropein induces apoptosis via abrogating NF-κB activation cascade in estrogen receptor-negative breast cancer cells

(2018) Lian Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Sorcin a Potential Molecular Target for Cancer Therapy

(2018) Bano Shabnam et al.   Translational Oncology

Googling the Guggul (Commiphora and Boswellia) for Prevention of Chronic Diseases

(2018) Ajaikumar B. Kunnumakkara et al.   Frontiers in Pharmacology

The Role of Signal Transducer and Activator of Transcription 3 (STAT3) and Its Targeted Inhibition in Hematological Malignancies

(2018) Loukik Arora et al.   Cancers

Boswellia serrata oleo-gum-resin and β-boswellic acid inhibits HSV-1 infection in vitro through modulation of NF-кB and p38 MAP kinase signaling

(2018) Debayan Goswami et al.   PHYTOMEDICINE

Thymoquinone Inhibits Bone Metastasis of Breast Cancer Cells Through Abrogation of the CXCR4 Signaling Axis

(2018) Muthu K. Shanmugam et al.   Frontiers in Pharmacology

N-Substituted Pyrido-1,4-Oxazin-3-Ones Induce Apoptosis of Hepatocellular Carcinoma Cells by Targeting NF-κB Signaling Pathway

(2018) Chakrabhavi Dhananjaya Mohan et al.   Frontiers in Pharmacology

Targeting STAT3 and oxidative phosphorylation in oncogene-addicted tumors

(2018) Matilda Lee et al.   Redox Biology

Identification of a natural inhibitor of methionine adenosyltransferase 2A regulating one-carbon metabolism in keratinocytes

(2018) Jing Bai et al.   EBioMedicine

Potential application of zerumbone in the prevention and therapy of chronic human diseases

(2018) Yogendra Prakash Singh et al.   Journal of Functional Foods

Do STAT3 inhibitors have potential in the future for cancer therapy?

(2017) Andrea L.A. Wong et al.   EXPERT OPINION ON INVESTIGATIONAL DRUGS

Antiulcer properties of fruits and vegetables: A mechanism based perspective

(2017) Choudhary Harsha et al.   FOOD AND CHEMICAL TOXICOLOGY

11-Keto-β-Boswellic Acid Inhibits Lymphocyte (CD3) Infiltration Into Pancreatic Islets of Young None Obese Diabetic (NOD) Mice

(2017) Ahmed Shehata et al.   HORMONE AND METABOLIC RESEARCH

The Role of Resveratrol in Cancer Therapy

(2017) Jeong-Hyeon Ko et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Role of 3-Acetyl-11-Keto-Beta-Boswellic Acid in Counteracting LPS-Induced Neuroinflammation via Modulation of miRNA-155

(2017) Aya Shoukry Sayed et al.   MOLECULAR NEUROBIOLOGY

IN0523 (Urs-12-ene-3α,24β-diol) a plant based derivative of boswellic acid protect Cisplatin induced urogenital toxicity

(2017) Amarinder Singh et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

A novel benzimidazole derivative, MBIC inhibits tumor growth and promotes apoptosis via activation of ROS-dependent JNK signaling pathway in hepatocellular carcinoma

(2017) Xiaoyun Dai et al.   Oncotarget

Nimbolide-Induced Oxidative Stress Abrogates STAT3 Signaling Cascade and Inhibits Tumor Growth in Transgenic Adenocarcinoma of Mouse Prostate Model

(2016) Jingwen Zhang et al.   ANTIOXIDANTS & REDOX SIGNALING

Curcumin and Boswellia serrata gum resin extract inhibit chikungunya and vesicular stomatitis virus infections in vitro

(2016) Christine von Rhein et al.   ANTIVIRAL RESEARCH

Cardamonin represses proliferation, invasion, and causes apoptosis through the modulation of signal transducer and activator of transcription 3 pathway in prostate cancer

(2016) Jingwen Zhang et al.   APOPTOSIS

Boswellic acid disables signal transduction of IL-6–STAT-3 in Ehrlich ascites tumor bearing irradiated mice

(2016) Enas Mahmoud Moustafa et al.   Biochemistry and Cell Biology

Curcumin, the golden nutraceutical: multitargeting for multiple chronic diseases

(2016) Ajaikumar B Kunnumakkara et al.   BRITISH JOURNAL OF PHARMACOLOGY

The potential role of boswellic acids in cancer prevention and treatment

(2016) Nand Kishor Roy et al.   CANCER LETTERS

Animal models of inflammatory bowel disease

(2016) George Kolios   CURRENT OPINION IN GASTROENTEROLOGY

Antioxidant effects of hydroxysafflor yellow A and acetyl-11-keto-β-boswellic acid in combination on isoproterenol-induced myocardial injury in rats

(2016) MINCHUN CHEN et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Telomerase reverse transcriptase promotes cancer cell proliferation by augmenting tRNA expression

(2016) Ekta Khattar et al.   JOURNAL OF CLINICAL INVESTIGATION

Pharmacology of Ischemia–Reperfusion. Translational Research Considerations

(2016) Beatriz Prieto-Moure et al.   JOURNAL OF INVESTIGATIVE SURGERY

Co-administration of 3-Acetyl-11-Keto-Beta-Boswellic Acid Potentiates the Protective Effect of Celecoxib in Lipopolysaccharide-Induced Cognitive Impairment in Mice: Possible Implication of Anti-inflammatory and Antiglutamatergic Pathways

(2016) Aya Shoukry Sayed et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Alpha-boswellic acid protects against ethanol-induced gastric injury in rats: involvement of nuclear factor erythroid-2-related factor 2/heme oxygenase-1 pathway

(2016) Yikai Zhang et al.   JOURNAL OF PHARMACY AND PHARMACOLOGY

Ascochlorin Enhances the Sensitivity of Doxorubicin Leading to the Reversal of Epithelial-to-Mesenchymal Transition in Hepatocellular Carcinoma

(2016) Xiaoyun Dai et al.   MOLECULAR CANCER THERAPEUTICS

The Effects of Alpha Boswellic Acid on Reelin Expression and Tau Phosphorylation in Human Astrocytes

(2016) Esmat Fathi et al.   NEUROMOLECULAR MEDICINE

Epigenetic changes in diabetes

(2016) Rami Al-Haddad et al.   NEUROSCIENCE LETTERS

Targeting transcription factor STAT3 for cancer prevention and therapy

(2016) Edna Zhi Pei Chai et al.   PHARMACOLOGY & THERAPEUTICS

A single-dose, randomized, cross-over, two-way, open-label study for comparing the absorption of boswellic acids and its lecithin formulation

(2016) Antonella Riva et al.   PHYTOMEDICINE

Aqueous and Ethanolic Extracts ofBoswellia serrataProtect Against Focal Cerebral Ischemia and Reperfusion Injury in Rats

(2016) Fatemeh Forouzanfar et al.   PHYTOTHERAPY RESEARCH

Activation of mutantTERTpromoter by RAS-ERK signaling is a key step in malignant progression of BRAF-mutant human melanomas

(2016) Yinghui Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Multi-Targeted Agents in Cancer Cell Chemosensitization: What We Learnt from Curcumin Thus Far

(2016) Devivasha Bordoloi et al.   Recent Patents on Anti-Cancer Drug Discovery

Cancer prevention and therapy through the modulation of transcription factors by bioactive natural compounds

(2016) Muthu K Shanmugam et al.   SEMINARS IN CANCER BIOLOGY

Targeting arachidonic acid pathway by natural products for cancer prevention and therapy

(2016) Nagendra Sastry Yarla et al.   SEMINARS IN CANCER BIOLOGY

Targeting multiple oncogenic pathways for the treatment of hepatocellular carcinoma

(2016) Supritha G. Swamy et al.   Targeted Oncology

Reversal of the multidrug resistance of human ileocecal adenocarcinoma cells by acetyl-11-keto-β-boswellic acid via downregulation of P-glycoprotein signals

(2016) Xia Xue et al.   BioScience Trends

Long-Range Chromatin Interactions Drive Mutant TERT Promoter Activation

(2016) S. C. Ak nc lar et al.   Cancer Discovery

Capsazepine inhibits JAK/STAT3 signaling, tumor growth, and cell survival in prostate cancer

(2016) Jong Hyun Lee et al.   Oncotarget

Interplay between cell cycle and autophagy induced by boswellic acid analog

(2016) Anup S. Pathania et al.   Scientific Reports

NF-κB in cancer therapy

(2015) Feng Li et al.   ARCHIVES OF TOXICOLOGY

Analysis of the intricate relationship between chronic inflammation and cancer

(2015) Edna Zhi Pei Chai et al.   BIOCHEMICAL JOURNAL

Global cancer statistics, 2012

(2015) Lindsey A. Torre et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Novel Evidence for Curcumin and Boswellic Acid-Induced Chemoprevention through Regulation of miR-34a and miR-27a in Colorectal Cancer

(2015) S. Toden et al.   Cancer Prevention Research

Quantitative assessment of telomerase components in cancer cell lines

(2015) Semih Can Akıncılar et al.   FEBS LETTERS

Boswellic acid attenuates asthma phenotype by downregulation of GATA3 via nhibition of PSTAT6

(2015) X. Zhou et al.   GENETICS AND MOLECULAR RESEARCH

11-Keto-β-Boswellic Acids Prevent Development of Autoimmune Reactions, Insulitis and Reduce Hyperglycemia During Induction of Multiple Low-Dose Streptozotocin (MLD-STZ) Diabetes in Mice

(2015) A. Shehata et al.   HORMONE AND METABOLIC RESEARCH

Methylsulfonylmethane and boswellic acids versus glucosamine sulfate in the treatment of knee arthritis: Randomized trial

(2015) Angela Notarnicola et al.   INTERNATIONAL JOURNAL OF IMMUNOPATHOLOGY AND PHARMACOLOGY

The anti-angiogenic and cytotoxic effects of the boswellic acid analog BA145 are potentiated by autophagy inhibitors

(2015) Anup S Pathania et al.   Molecular Cancer

Ascochlorin, an isoprenoid antibiotic inhibits growth and invasion of hepatocellular carcinoma by targeting STAT3 signaling cascade through the induction of PIAS3

(2015) Xiaoyun Dai et al.   Molecular Oncology

Antioxidant Phytochemicals for the Prevention and Treatment of Chronic Diseases

(2015) Yu-Jie Zhang et al.   MOLECULES

Potential of butein, a tetrahydroxychalcone to obliterate cancer

(2015) Ganesan Padmavathi et al.   PHYTOMEDICINE

Prospects of Boswellic Acids as Potential Pharmaceutics

(2015) Zhiyong Du et al.   PLANTA MEDICA

An oncogenic role of Agrin in regulating focal adhesion integrity in hepatocellular carcinoma

(2015) Sayan Chakraborty et al.   Nature Communications

Phytochemica: a platform to explore phytochemicals of medicinal plants

(2015) Shivalika Pathania et al.   Database-The Journal of Biological Databases and Curation

Natural Bioactives in Cancer Treatment and Prevention

(2015) Yih-Shou Hsieh et al.   Biomed Research International

γ-tocotrienol inhibits angiogenesis-dependent growth of human hepatocellular carcinoma through abrogation of AKT/mTOR pathway in an orthotopic mouse model

(2015) Kodappully Sivaraman Siveen et al.   Oncotarget

Targeting the STAT3 signaling pathway in cancer: Role of synthetic and natural inhibitors

(2014) Kodappully Sivaraman Siveen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Investigating permeability related hurdles in oral delivery of 11-keto-β-boswellic acid

(2014) Pravin Bagul et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Development of a Novel Azaspirane That Targets the Janus Kinase-Signal Transducer and Activator of Transcription (STAT) Pathway in Hepatocellular Carcinomain Vitroandin Vivo

(2014) Chakrabhavi Dhananjaya Mohan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of STAT3 dimerization and acetylation by garcinol suppresses the growth of human hepatocellular carcinoma in vitro and in vivo

(2014) Gautam Sethi et al.   Molecular Cancer

Posttreatment with 11-Keto-β-Boswellic Acid Ameliorates Cerebral Ischemia–Reperfusion Injury: Nrf2/HO-1 Pathway as a Potential Mechanism

(2014) Yi Ding et al.   MOLECULAR NEUROBIOLOGY

Oleanane triterpenoids in the prevention and therapy of breast cancer: current evidence and future perspectives

(2014) Nisha R. Parikh et al.   PHYTOCHEMISTRY REVIEWS

Neuroprotection by Acetyl-11-Keto-β-Boswellic Acid, in Ischemic Brain Injury Involves the Nrf2/HO-1 defense Pathway

(2014) Yi Ding et al.   Scientific Reports

Caspase Mediated Synergistic Effect ofBoswellia serrataExtract in Combination with Doxorubicin against Human Hepatocellular Carcinoma

(2014) Mohammad Ahmed Khan et al.   Biomed Research International

Novel Medicines and Strategies in Cancer Treatment and Prevention

(2014) Chih-Hsin Tang et al.   Biomed Research International

NF-κB Down–regulation and PARP Cleavage by novel 3-α-butyryloxy-β-boswellic Acid Results in Cancer Cell Specific Apoptosis and in vivo Tumor Regression

(2013) Yasrib Qurishi et al.   Anti-Cancer Agents in Medicinal Chemistry

The tyrosine phosphatase SHP-1 inhibits proliferation of activated hepatic stellate cells by impairing PDGF receptor signaling

(2013) Elena Tibaldi et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Emodin inhibits growth and induces apoptosis in an orthotopic hepatocellular carcinoma model by blocking activation of STAT3

(2013) Aruljothi Subramaniam et al.   BRITISH JOURNAL OF PHARMACOLOGY

Bioavailability of phytochemicals and its enhancement by drug delivery systems

(2013) Farrukh Aqil et al.   CANCER LETTERS

Garcinol, a Polyisoprenylated Benzophenone Modulates Multiple Proinflammatory Signaling Cascades Leading to the Suppression of Growth and Survival of Head and Neck Carcinoma

(2013) F. Li et al.   Cancer Prevention Research

Natural Bioactives and Phytochemicals Serve in Cancer Treatment and Prevention

(2013) Shun-Fa Yang et al.   Evidence-based Complementary and Alternative Medicine

Application of nanotechnology in improving bioavailability and bioactivity of diet-derived phytochemicals

(2013) Shu Wang et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

The selective 5-LOX inhibitor 11-keto-β-boswellic acid protects against myocardial ischemia reperfusion injury in rats: involvement of redox and inflammatory cascades

(2013) Shimaa M. Elshazly et al.   NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY

Oral and topical boswellic acid attenuates mouse osteoarthritis

(2013) Q. Wang et al.   OSTEOARTHRITIS AND CARTILAGE

Biotransformation of 11-keto-β-boswellic acid by Cunninghamella blakesleana

(2013) Yue Wang et al.   PHYTOCHEMISTRY

Emodin Suppresses Migration and Invasion through the Modulation of CXCR4 Expression in an Orthotopic Model of Human Hepatocellular Carcinoma

(2013) Kanjoormana Aryan Manu et al.   PLoS One

Potential role of signal transducer and activator of transcription (STAT)3 signaling pathway in inflammation, survival, proliferation and invasion of hepatocellular carcinoma

(2012) Aruljothi Subramaniam et al.   BIOCHIMICA ET BIOPHYSICA ACTA-REVIEWS ON CANCER

Boswellic acid induces epigenetic alterations by modulating DNA methylation in colorectal cancer cells

(2012) Yan Shen et al.   CANCER BIOLOGY & THERAPY

Boswellic acid exerts antitumor effects in colorectal cancer cells by modulating expression of the let-7 and miR-200 microRNA family

(2012) M. Takahashi et al.   CARCINOGENESIS

First Evidence That  -Tocotrienol Inhibits the Growth of Human Gastric Cancer and Chemosensitizes It to Capecitabine in a Xenograft Mouse Model through the Modulation of NF- B Pathway

(2012) K. A. Manu et al.   CLINICAL CANCER RESEARCH

Enhanced absorption of boswellic acids by a lecithin delivery form (Phytosome®) of Boswellia extract

(2012) Jan Hüsch et al.   FITOTERAPIA

In vitro metabolism, permeation, and brain availability of six major boswellic acids from Boswellia serrata gum resins

(2012) Kathleen Gerbeth et al.   FITOTERAPIA

PARP cleavage and perturbance in mitochondrial membrane potential by 3-α-propionyloxy-β-boswellic acid results in cancer cell death and tumor regression in murine models

(2012) Yasrib Qurishi et al.   Future Oncology

Embelin inhibits growth and induces apoptosis through the suppression of Akt/mTOR/S6K1 signaling cascades

(2012) Seong Won Kim et al.   PROSTATE

Targeting PPARγSignaling Cascade for the Prevention and Treatment of Prostate Cancer

(2012) Sakshi Sikka et al.   PPAR Research

The “MESACA” study: Methylsulfonylmethane and boswellic acids in the treatment of gonarthrosis

(2011) Angela Notarnicola et al.   ADVANCES IN THERAPY

Acyl derivatives of boswellic acids as inhibitors of NF-κB and STATs

(2011) Ajay Kumar et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Boswellia serrata acts on cerebral edema in patients irradiated for brain tumors

(2011) Simon Kirste et al.   CANCER

Antitumor properties of Boswellic acid against Ehrlich ascites cells bearing mouse

(2011) S.S. Agrawal et al.   FOOD AND CHEMICAL TOXICOLOGY

Boswellic acid inhibits growth and metastasis of human colorectal cancer in orthotopic mouse model by downregulating inflammatory, proliferative, invasive and angiogenic biomarkers

(2011) Vivek R. Yadav et al.   INTERNATIONAL JOURNAL OF CANCER

Growth inhibitory, apoptotic and anti-inflammatory activities displayed by a novel modified triterpenoid, cyano enone of methyl boswellates

(2011) Palaniyandi Ravanan et al.   JOURNAL OF BIOSCIENCES

Honokiol inhibits signal transducer and activator of transcription-3 signaling, proliferation, and survival of hepatocellular carcinoma cells via the protein tyrosine phosphatase SHP-1

(2011) Peramaiyan Rajendran et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Increased Bioavailability of 11-Keto-β-Boswellic Acid Following Single Oral Dose Frankincense Extract Administration After a Standardized Meal in Healthy Male Volunteers: Modeling and Simulation Considerations for Evaluating Drug Exposures

(2011) Carsten Skarke et al.   JOURNAL OF CLINICAL PHARMACOLOGY

A Novel cyano derivative of 11-Keto-β-Boswellic acid causes apoptotic death by disrupting PI3K/AKT/Hsp-90 cascade, mitochondrial integrity, and other cell survival signaling events in HL-60 cells

(2011) Sheema Khan et al.   MOLECULAR CARCINOGENESIS

Targeting Cell Signaling and Apoptotic Pathways by Dietary Agents: Role in the Prevention and Treatment of Cancer

(2011) Muthu Shanmugam et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Prevention of multiple low-dose streptozotocin (MLD-STZ) diabetes in mice by an extract from gum resin of Boswellia serrata (BE)

(2011) Ahmed M. Shehata et al.   PHYTOMEDICINE

Boswellic Acid Suppresses Growth and Metastasis of Human Pancreatic Tumors in an Orthotopic Nude Mouse Model through Modulation of Multiple Targets

(2011) Byoungduck Park et al.   PLoS One

γ-Tocotrienol is a novel inhibitor of constitutive and inducible STAT3 signalling pathway in human hepatocellular carcinoma: potential role as an antiproliferative, pro-apoptotic and chemosensitizing agent

(2010) Peramaiyan Rajendran et al.   BRITISH JOURNAL OF PHARMACOLOGY

A propionyloxy derivative of 11-keto-β-boswellic acid induces apoptosis in HL-60 cells mediated through topoisomerase I & II inhibition

(2010) Gousia Chashoo et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Suppression of Signal Transducer and Activator of Transcription 3 Activation by Butein Inhibits Growth of Human Hepatocellular Carcinoma In Vivo

(2010) Peramaiyan Rajendran et al.   CLINICAL CANCER RESEARCH

Topical Boswellic acids for treatment of photoaged skin

(2010) Piergiacomo Calzavara-Pinton et al.   Dermatologic Therapy

Frankincense oil derived from Boswellia carteri induces tumor cell specific cytotoxicity

(2009) Mark Barton Frank et al.   BMC Complementary and Alternative Medicine

Acetyl-11-Keto- -Boswellic Acid Inhibits Prostate Tumor Growth by Suppressing Vascular Endothelial Growth Factor Receptor 2-Mediated Angiogenesis

(2009) X. Pang et al.   CANCER RESEARCH

Recent developments in anti-inflammatory natural products

(2009) Raju Gautam et al.   MEDICINAL RESEARCH REVIEWS

Effects of Topical Boswellic Acid on Photo and Age-Damaged Skin: Clinical, Biophysical, and Echographic Evaluations in a Double-Blind, Randomized, Split-Face Study

(2009) Alessandra Pedretti et al.   PLANTA MEDICA

Potential pharmacological control of the NF-κB pathway

(2009) Gautam Sethi et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

Inhibitory effect of acetyl-11-keto-β-boswellic acid on androgen receptor by interference of Sp1 binding activity in prostate cancer cells

(2008) Hui-Qing Yuan et al.   BIOCHEMICAL PHARMACOLOGY

Acetyl-Keto- -Boswellic Acid Induces Apoptosis through a Death Receptor 5-Mediated Pathway in Prostate Cancer Cells

(2008) M. Lu et al.   CANCER RESEARCH

Metabolism of Boswellic Acids in Vitro and in Vivo

(2008) P. Kruger et al.   DRUG METABOLISM AND DISPOSITION

Permeation of Boswellia extract in the Caco-2 model and possible interactions of its constituents KBA and AKBA with OATP1B3 and MRP2

(2008) Phillip Krüger et al.   EUROPEAN JOURNAL OF PHARMACEUTICAL SCIENCES

Nuclear Factor-κB Activation: From Bench to Bedside

(2008) Gautam Sethi et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

The gastric ulcer protective effect of boswellic acids, a leukotriene inhibitor from Boswellia serrata, in rats

(2008) S. Singh et al.   PHYTOMEDICINE

A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee

(2008) Krishanu Sengupta et al.   ARTHRITIS RESEARCH & THERAPY

Antiinflammatory and Antiatherogenic Effects of the NF-κB Inhibitor Acetyl-11-Keto-β-Boswellic Acid in LPS-Challenged ApoE −/− Mice

(2007) Clarisse Cuaz-Pérolin et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY