Dihydromyricetin protects neurons in an MPTP-induced model of Parkinson's disease by suppressing glycogen synthase kinase-3 beta activity

A novel PI3K/AKT signaling axis mediates Nectin-4-induced gallbladder cancer cell proliferation, metastasis and tumor growth

(2016) Yijian Zhang et al.   CANCER LETTERS

Presymptomatic MPTP Mice Show Neurotrophic S100B/mRAGE Striatal Levels

(2016) Sofia D. Viana et al.   CNS Neuroscience & Therapeutics

PI3K/AKT/mTOR inhibition in combination with doxorubicin is an effective therapy for leiomyosarcoma

(2016) Yael Babichev et al.   Journal of Translational Medicine

Neuroprotective effects of ginsenoside Rg1 through the Wnt/β-catenin signaling pathway in both in vivo and in vitro models of Parkinson's disease

(2016) Tingting Zhou et al.   NEUROPHARMACOLOGY

Serotonin in Parkinson's disease

(2015) Marios Politis et al.   BEHAVIOURAL BRAIN RESEARCH

The many roads to mitochondrial dysfunction in neuroimmune and neuropsychiatric disorders

(2015) Gerwyn Morris et al.   BMC Medicine

Neuroprotective effects of an oxyntomodulin analogue in the MPTP mouse model of Parkinson's disease

(2015) WeiZhen Liu et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Ginsenoside Rd Protects SH-SY5Y Cells against 1-Methyl-4-phenylpyridinium Induced Injury

(2015) Yang Liu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Suppression of Inflammatory Responses by Dihydromyricetin, a Flavonoid from Ampelopsis grossedentata, via Inhibiting the Activation of NF-κB and MAPK Signaling Pathways

(2015) X. L. Hou et al.   JOURNAL OF NATURAL PRODUCTS

Parkinson's disease

(2015) Lorraine V Kalia et al.   LANCET

Dihydromyricetin protects endothelial cells from hydrogen peroxide-induced oxidative stress damage by regulating mitochondrial pathways

(2015) Xiaolong Hou et al.   LIFE SCIENCES

Dihydromyricetin improves skeletal muscle insulin resistance by inducing autophagy via the AMPK signaling pathway

(2015) Linying Shi et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Neurotoxin Mechanisms and Processes Relevant to Parkinson’s Disease: An Update

(2015) Juan Segura-Aguilar et al.   NEUROTOXICITY RESEARCH

Glycogen synthase kinase-3 beta (GSK-3β) signaling: Implications for Parkinson's disease

(2015) Mojtaba Golpich et al.   PHARMACOLOGICAL RESEARCH

Characterization of Staphylococcus aureus from Humans and a Comparison with İsolates of Animal Origin, in North Dakota, United States

(2015) Valeria Velasco et al.   PLoS One

Dihydromyricetin Enhances the Chemo-Sensitivity of Nedaplatin via Regulation of the p53/Bcl-2 Pathway in Hepatocellular Carcinoma Cells

(2015) Lianggui Jiang et al.   PLoS One

Phytoestrogen β-Ecdysterone Protects PC12 Cells Against MPP+-Induced NeurotoxicityIn Vitro: Involvement of PI3K-Nrf2-Regulated Pathway

(2015) Yu Zou et al.   TOXICOLOGICAL SCIENCES

Sigma-1 receptor deficiency reduces MPTP-induced parkinsonism and death of dopaminergic neurons

(2015) J Hong et al.   Cell Death & Disease

Optimization of 6-Heterocyclic-2-(1H-pyrazol-1-yl)-N-(pyridin-2-yl)pyrimidin-4-amine as Potent Adenosine A2A Receptor Antagonists for the Treatment of Parkinson’s Disease

(2014) Jiyue Zheng et al.   ACS Chemical Neuroscience

Dihydromyricetin ameliorates the oxidative stress response induced by methylglyoxal via the AMPK/GLUT4 signaling pathway in PC12 cells

(2014) Baoping Jiang et al.   BRAIN RESEARCH BULLETIN

The Centrality of Mitochondria in the Pathogenesis and Treatment of Parkinson's Disease

(2014) Angelique Camilleri et al.   CNS Neuroscience & Therapeutics

Dihydromyricetin Ameliorates Behavioral Deficits and Reverses Neuropathology of Transgenic Mouse Models of Alzheimer’s Disease

(2014) Jing Liang et al.   NEUROCHEMICAL RESEARCH

(6aR)-11-Amino-N-propyl-noraporphine, a new dopamine D2 and serotonin 5-HT1A dual agonist, elicits potent antiparkinsonian action and attenuates levodopa-induced dyskinesia in a 6-OHDA-lesioned rat model of Parkinson's disease

(2014) Rui Zhao et al.   PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR

Recrystallization of Dihydromyricetin from Ampelopsis grossedentata and Its Anti-Oxidant Activity Evaluation

(2014) Wenzhen Liao et al.   REJUVENATION RESEARCH

Dihydromyricetin promotes hepatocellular carcinoma regression via a p53 activation-dependent mechanism

(2014) Qingyu Zhang et al.   Scientific Reports

A reduction in reactive oxygen species contributes to dihydromyricetin-induced apoptosis in human hepatocellular carcinoma cells

(2014) Bin Liu et al.   Scientific Reports

Paeoniflorin, a Natural Neuroprotective Agent, Modulates Multiple Anti-Apoptotic and Pro-apoptotic Pathways in Differentiated PC12 Cells

(2013) Di Wang et al.   CELLULAR AND MOLECULAR NEUROBIOLOGY

Update 1 of: Recent Progress in Development of Dopamine Receptor Subtype-Selective Agents: Potential Therapeutics for Neurological and Psychiatric Disorders

(2013) Na Ye et al.   CHEMICAL REVIEWS

Glycogen synthase kinase 3 substrates in mood disorders and schizophrenia

(2013) Adam R. Cole   FEBS Journal

A Critical Evaluation of Behavioral Rodent Models of Motor Impairment Used for Screening of Antiparkinsonian Activity: The Case of Adenosine A2A Receptor Antagonists

(2013) Annalisa Pinna et al.   NEUROTOXICITY RESEARCH

Glycogen Synthase Kinase-3 Inhibitors as Potent Therapeutic Agents for the Treatment of Parkinson Disease.

(2012) J. A. Morales-García et al.   ACS Chemical Neuroscience

Dihydromyricetin As a Novel Anti-Alcohol Intoxication Medication

(2012) Y. Shen et al.   JOURNAL OF NEUROSCIENCE

Identification ofN-Propylnoraporphin-11-yl 5-(1,2-Dithiolan-3-yl)pentanoate as a New Anti-Parkinson's Agent Possessing a Dopamine D2and Serotonin 5-HT1ADual-Agonist Profile

(2011) Hai Zhang et al.   JOURNAL OF MEDICINAL CHEMISTRY

Neuroprotective effects of atypical D1receptor agonist SKF83959 are mediated via D1receptor-dependent inhibition of glycogen synthase kinase-3β and a receptor-independent anti-oxidative action

(2007) Yang Yu et al.   JOURNAL OF NEUROCHEMISTRY