Mitochondrial Dysfunction and Biogenesis in Neurodegenerative diseases: Pathogenesis and Treatment

Mitochondrial Amyloid-β Levels are Associated with the Extent of Mitochondrial Dysfunction in Different Brain Regions and the Degree of Cognitive Impairment in Alzheimer's Transgenic Mice

(2017) Natasa Dragicevic et al.   JOURNAL OF ALZHEIMERS DISEASE

Mitochondria-Targeted Antioxidants Protect Against Amyloid-β Toxicity in Alzheimer's Disease Neurons

(2017) Maria Manczak et al.   JOURNAL OF ALZHEIMERS DISEASE

Nutraceuticals in Parkinson’s Disease

(2016) Liting Hang et al.   NEUROMOLECULAR MEDICINE

The emerging role of Nrf2 in mitochondrial function

(2015) Albena T. Dinkova-Kostova et al.   FREE RADICAL BIOLOGY AND MEDICINE

Glycogen synthase kinase-3 beta (GSK-3β) signaling: Implications for Parkinson's disease

(2015) Mojtaba Golpich et al.   PHARMACOLOGICAL RESEARCH

Modulation of Mitochondrial Complex I Activity Averts Cognitive Decline in Multiple Animal Models of Familial Alzheimer's Disease

(2015) Liang Zhang et al.   EBioMedicine

Mitofusin 2-Deficiency Suppresses Cell Proliferation through Disturbance of Autophagy

(2015) Yanhong Ding et al.   PLoS One

Sex differences in mitochondrial biogenesis determine neuronal death and survival in response to oxygen glucose deprivation and reoxygenation

(2014) Jaswinder Sharma et al.   BMC NEUROSCIENCE

Mitochondrial Biogenesis: A Therapeutic Target for Neurodevelopmental Disorders and Neurodegenerative Diseases

(2014) Martine Uittenbogaard et al.   CURRENT PHARMACEUTICAL DESIGN

Annonacin, a natural lipophilic mitochondrial complex I inhibitor, increases phosphorylation of tau in the brain of FTDP-17 transgenic mice

(2014) Elizabeth S. Yamada et al.   EXPERIMENTAL NEUROLOGY

Neuroprotective effects of the mitochondria-targeted antioxidant MitoQ in a model of inherited amyotrophic lateral sclerosis

(2014) Ernesto Miquel et al.   FREE RADICAL BIOLOGY AND MEDICINE

Preconditioning as a Potential Strategy for the Prevention of Parkinson’s Disease

(2014) Mojtaba Golpich et al.   MOLECULAR NEUROBIOLOGY

Prospects for neuroprotective therapies in prodromal Huntington's disease

(2014) Abhishek Chandra et al.   MOVEMENT DISORDERS

Mutant TDP-43 Deregulates AMPK Activation by PP2A in ALS Models

(2014) Nirma D. Perera et al.   PLoS One

Mitochondrial Dysfunctions in Neurodegenerative Diseases: Relevance to Alzheimer’s Disease

(2014) Jana Hroudová et al.   Biomed Research International

Differential effects of complex II on mitochondrial ROS production and their relation to cardioprotective pre- and postconditioning

(2013) Stefan Dröse   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

March separate, strike together — Role of phosphorylated TAU in mitochondrial dysfunction in Alzheimer's disease

(2013) Anne Eckert et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mitochondria-targeted antioxidants for treatment of Parkinson's disease: Preclinical and clinical outcomes

(2013) Huajun Jin et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

First-in-class cardiolipin-protective compound as a therapeutic agent to restore mitochondrial bioenergetics

(2013) Hazel H Szeto   BRITISH JOURNAL OF PHARMACOLOGY

Sirtuin deacetylases in neurodegenerative diseases of aging

(2013) Adrianna Z Herskovits et al.   CELL RESEARCH

PGC-1α, mitochondrial dysfunction, and Huntington's disease

(2013) Ashu Johri et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Diseases of the Brain

(2013) Rajnish K. Chaturvedi et al.   FREE RADICAL BIOLOGY AND MEDICINE

PINK1 drives Parkin self-association and HECT-like E3 activity upstream of mitochondrial binding

(2013) Michael Lazarou et al.   JOURNAL OF CELL BIOLOGY

Beyond the mitochondrion: cytosolic PINK1 remodels dendrites through Protein Kinase A

(2013) Ruben K. Dagda et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondrial quality, dynamics and functional capacity in Parkinson’s disease cybrid cell lines selected for Lewy body expression

(2013) Emily N Cronin-Furman et al.   Molecular Neurodegeneration

Expression of zinc-deficient human superoxide dismutase in Drosophila neurons produces a locomotor defect linked to mitochondrial dysfunction

(2013) Sepehr Bahadorani et al.   NEUROBIOLOGY OF AGING

Nicotinamide riboside restores cognition through an upregulation of proliferator-activated receptor-γ coactivator 1α regulated β-secretase 1 degradation and mitochondrial gene expression in Alzheimer's mouse models

(2013) Bing Gong et al.   NEUROBIOLOGY OF AGING

Mitochondrial Biogenesis through Activation of Nuclear Signaling Proteins

(2013) J. E. Dominy et al.   Cold Spring Harbor Perspectives in Biology

Mechanisms of Mitochondrial Fission and Fusion

(2013) A. M. van der Bliek et al.   Cold Spring Harbor Perspectives in Biology

Effects of Germinated Brown Rice and Its Bioactive Compounds on the Expression of the Peroxisome Proliferator-Activated Receptor Gamma Gene

(2013) Mustapha Imam et al.   Nutrients

Sirtuins in neurodegenerative diseases: an update on potential mechanisms

(2013) Sang-Won Min et al.   Frontiers in Aging Neuroscience

Biphasic modulation of the mitochondrial electron transport chain in myocardial ischemia and reperfusion

(2012) Hsin-Ling Lee et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Elevated PGC-1α Activity Sustains Mitochondrial Biogenesis and Muscle Function without Extending Survival in a Mouse Model of Inherited ALS

(2012) Sandrine Da Cruz et al.   Cell Metabolism

Mitochondrial dysfunction in Parkinson's disease: molecular mechanisms and pathophysiological consequences

(2012) Nicole Exner et al.   EMBO JOURNAL

Redox regulation of protein misfolding, mitochondrial dysfunction, synaptic damage, and cell death in neurodegenerative diseases

(2012) Tomohiro Nakamura et al.   EXPERIMENTAL NEUROLOGY

Pharmacological manipulation of peroxisome proliferator-activated receptor γ (PPARγ) reveals a role for anti-oxidant protection in a model of Parkinson's disease

(2012) Heather L. Martin et al.   EXPERIMENTAL NEUROLOGY

Redox regulation of mitochondrial biogenesis

(2012) Claude A. Piantadosi et al.   FREE RADICAL BIOLOGY AND MEDICINE

The Peroxisome Proliferator-activated Receptor γ (PPARγ) Controls Natural Protective Mechanisms against Lipid Peroxidation in Amyotrophic Lateral Sclerosis

(2012) Valeria Benedusi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reactive oxygen/nitrogen species and their functional correlations in neurodegenerative diseases

(2012) Mahesh Ramalingam et al.   JOURNAL OF NEURAL TRANSMISSION

Peroxisome proliferator-activated receptors γ/mitochondrial uncoupling protein 2 signaling protects against seizure-induced neuronal cell death in the hippocampus following experimental status epilepticus

(2012) Yao-Chung Chuang et al.   Journal of Neuroinflammation

SIRT1 Protects against  -Synuclein Aggregation by Activating Molecular Chaperones

(2012) G. Donmez et al.   JOURNAL OF NEUROSCIENCE

AMP Kinase Activation Mitigates Dopaminergic Dysfunction and Mitochondrial Abnormalities in Drosophila Models of Parkinson's Disease

(2012) C.-H. Ng et al.   JOURNAL OF NEUROSCIENCE

Peroxisome Proliferator-Activated Receptor Gamma (PPAR-γ) and Neurodegenerative Disorders

(2012) Yu-Chang Chen et al.   MOLECULAR NEUROBIOLOGY

NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice

(2012) Michael T. Heneka et al.   NATURE

The sirtuin SIRT6 regulates lifespan in male mice

(2012) Yariv Kanfi et al.   NATURE

Prion-like behaviour and tau-dependent cytotoxicity of pyroglutamylated amyloid-β

(2012) Justin M. Nussbaum et al.   NATURE

Disruption of skeletal muscle mitochondrial network genes and miRNAs in amyotrophic lateral sclerosis

(2012) Aaron P. Russell et al.   NEUROBIOLOGY OF DISEASE

Exercise induces mitochondrial biogenesis after brain ischemia in rats

(2012) Q. Zhang et al.   NEUROSCIENCE

PGC-1  Rescues Huntington's Disease Proteotoxicity by Preventing Oxidative Stress and Promoting TFEB Function

(2012) T. Tsunemi et al.   Science Translational Medicine

RETRACTED: 6-OHDA-induced apoptosis and mitochondrial dysfunction are mediated by early modulation of intracellular signals and interaction of Nrf2 and NF-κB factors

(2012) Julio C. Tobón-Velasco et al.   TOXICOLOGY

Mitochondrial quality control: an integrated network of pathways

(2012) Fabian Fischer et al.   TRENDS IN BIOCHEMICAL SCIENCES

Impaired mitochondrial biogenesis contributes to depletion of functional mitochondria in chronic MPP+ toxicity: dual roles for ERK1/2

(2012) J H Zhu et al.   Cell Death & Disease

Mitochondrion-mediated cell death: dissecting yeast apoptosis for a better understanding of neurodegeneration

(2012) Ralf J. Braun   Frontiers in Oncology

Parkin, PINK1 and mitochondrial integrity: emerging concepts of mitochondrial dysfunction in Parkinson’s disease

(2011) Anna Pilsl et al.   ACTA NEUROPATHOLOGICA

Mitochondria and autophagy: Critical interplay between the two homeostats

(2011) Koji Okamoto et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Assessment of newly synthesized mitochondrial DNA using BrdU labeling in primary neurons from Alzheimer's disease mice: Implications for impaired mitochondrial biogenesis and synaptic damage

(2011) Marcus J. Calkins et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The dysfunction of hepatic transcriptional factors in mice with Huntington's Disease

(2011) Ming-Chang Chiang et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Mutant huntingtin, abnormal mitochondrial dynamics, defective axonal transport of mitochondria, and selective synaptic degeneration in Huntington's disease

(2011) P. Hemachandra Reddy et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

G37R SOD1 mutant alters mitochondrial complex I activity, Ca2+ uptake and ATP production

(2011) Evelyne Coussee et al.   CELL CALCIUM

Mitochondria as a Therapeutic Target for Aging and Neurodegenerative Diseases

(2011) P. H. Reddy et al.   Current Alzheimer Research

Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease

(2011) Ashu Johri et al.   HUMAN MOLECULAR GENETICS

Genetic mouse models for Parkinson's disease display severe pathology in glial cell mitochondria

(2011) S. Schmidt et al.   HUMAN MOLECULAR GENETICS

Negative Regulation of STAT3 Protein-mediated Cellular Respiration by SIRT1 Protein

(2011) Michel Bernier et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Dysfunction in Cancer Cells Due to Aberrant Mitochondrial Replication

(2011) Yuriy Shapovalov et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial dysfunction in patients with primary congenital insulin resistance

(2011) Alison Sleigh et al.   JOURNAL OF CLINICAL INVESTIGATION

Mitochondrial ATP synthase: architecture, function and pathology

(2011) An I. Jonckheere et al.   JOURNAL OF INHERITED METABOLIC DISEASE

Impaired mitochondrial biogenesis contributes to mitochondrial dysfunction in Alzheimer’s disease

(2011) Baiyang Sheng et al.   JOURNAL OF NEUROCHEMISTRY

Glycogen synthase kinase-3 inhibition reduces ischemic cerebral damage, restores impaired mitochondrial biogenesis and prevents ROS production

(2011) Alessandra Valerio et al.   JOURNAL OF NEUROCHEMISTRY

The role of mitochondria in neurodegenerative diseases

(2011) Massimiliano Filosto et al.   JOURNAL OF NEUROLOGY

High-level inhibition of mitochondrial complexes III and IV is required to increase glutamate release from the nerve terminal

(2011) Seán M Kilbride et al.   Molecular Neurodegeneration

Neuroprotective role of Sirt1 in mammalian models of Huntington's disease through activation of multiple Sirt1 targets

(2011) Mali Jiang et al.   NATURE MEDICINE

Amyloid β-induced ER stress is enhanced under mitochondrial dysfunction conditions

(2011) Rui O. Costa et al.   NEUROBIOLOGY OF AGING

PPARgamma rescue of the mitochondrial dysfunction in Huntington's disease

(2011) Ming-Chang Chiang et al.   NEUROBIOLOGY OF DISEASE

Life Span and Locomotor Activity Modification by Glucose and Polyphenols in Drosophila melanogaster Chronically Exposed to Oxidative Stress-stimuli: Implications in Parkinson’s Disease

(2011) Hector Flavio Ortega-Arellano et al.   NEUROCHEMICAL RESEARCH

Mitochondria: The Next (Neurode)Generation

(2011) Eric A. Schon et al.   NEURON

Review: The role of mitochondria in the pathogenesis of amyotrophic lateral sclerosis

(2011) L. M. Duffy et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Mitochondrial dysfunction in ALS

(2011) Mauro Cozzolino et al.   PROGRESS IN NEUROBIOLOGY

Mitochondria and the Autophagy-Inflammation-Cell Death Axis in Organismal Aging

(2011) D. R. Green et al.   SCIENCE

Mitochondrial protein quality control during biogenesis and aging

(2011) Brooke M. Baker et al.   TRENDS IN BIOCHEMICAL SCIENCES

Mitochondrial Complex I Activity and Oxidative Damage to Mitochondrial Proteins in the Prefrontal Cortex of Patients With Bipolar Disorder

(2010) Ana C. Andreazza et al.   ARCHIVES OF GENERAL PSYCHIATRY

Complex III-dependent superoxide production of brain mitochondria contributes to seizure-related ROS formation

(2010) Dominika Malinska et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

Metabolic control of mitochondrial biogenesis through the PGC-1 family regulatory network

(2010) Richard C. Scarpulla   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Mitochondrial transcription factor A (TFAM) polymorphisms and risk of late-onset Alzheimer's disease in Han Chinese

(2010) Qun Zhang et al.   BRAIN RESEARCH

Regulation of Skeletal Muscle Oxidative Capacity and Insulin Signaling by the Mitochondrial Rhomboid Protease PARL

(2010) Anthony E. Civitarese et al.   Cell Metabolism

Mitochondrial dynamics in cell death and neurodegeneration

(2010) Dong-Hyung Cho et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Sex Differences in the Phosphorylation of Mitochondrial Proteins Result in Reduced Production of Reactive Oxygen Species and Cardioprotection in Females

(2010) Claudia J. Lagranha et al.   CIRCULATION RESEARCH

Mitochondria-Targeted Antioxidant Peptides

(2010) Milagros Rocha et al.   CURRENT PHARMACEUTICAL DESIGN

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

(2010) J. Kim et al.   HUMAN MOLECULAR GENETICS

Modulation of energy deficiency in Huntington's disease via activation of the peroxisome proliferator-activated receptor gamma

(2010) Ming-Chang Chiang et al.   HUMAN MOLECULAR GENETICS

A pivotal role for PINK1 and autophagy in mitochondrial quality control: implications for Parkinson disease

(2010) C. T. Chu   HUMAN MOLECULAR GENETICS

Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation

(2010) R. K. Chaturvedi et al.   HUMAN MOLECULAR GENETICS

Proteasome and p97 mediate mitophagy and degradation of mitofusins induced by Parkin

(2010) Atsushi Tanaka et al.   JOURNAL OF CELL BIOLOGY

A metabolic shift induced by a PPAR panagonist markedly reduces the effects of pathogenic mitochondrial tRNA mutations

(2010) Tina Wenz et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

A neurological perspective on mitochondrial disease

(2010) Robert McFarland et al.   LANCET NEUROLOGY

Mitochondrial Dysfunction: Common Final Pathway in Brain Aging and Alzheimer’s Disease—Therapeutic Aspects

(2010) Walter E. Müller et al.   MOLECULAR NEUROBIOLOGY

Mitochondrial DNA haplogroups in early-onset Alzheimer's disease and frontotemporal lobar degeneration

(2010) Johanna Krüger et al.   Molecular Neurodegeneration

Mitochondrial fusion and fission in cell life and death

(2010) Benedikt Westermann   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mechanisms of mitophagy

(2010) Richard J. Youle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Mitochondrial DNA Mutations Induce Mitochondrial Dysfunction, Apoptosis and Sarcopenia in Skeletal Muscle of Mitochondrial DNA Mutator Mice

(2010) Asimina Hiona et al.   PLoS One

Sirtuin 3, a New Target of PGC-1α, Plays an Important Role in the Suppression of ROS and Mitochondrial Biogenesis

(2010) Xingxing Kong et al.   PLoS One

ALS-linked mutant superoxide dismutase 1 (SOD1) alters mitochondrial protein composition and decreases protein import

(2010) Q. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

PGC-1 , A Potential Therapeutic Target for Early Intervention in Parkinson's Disease

(2010) B. Zheng et al.   Science Translational Medicine

Sirtuin regulation of mitochondria: energy production, apoptosis, and signaling

(2010) Eric Verdin et al.   TRENDS IN BIOCHEMICAL SCIENCES

PINK1 Is Selectively Stabilized on Impaired Mitochondria to Activate Parkin

(2010) Derek P. Narendra et al.   PLOS BIOLOGY

Mitochondria Targeted Peptides Protect Against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine Neurotoxicity

(2009) Lichuan Yang et al.   ANTIOXIDANTS & REDOX SIGNALING

Regulation of neuron mitochondrial biogenesis and relevance to brain health

(2009) Isaac G. Onyango et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Phosphorus and proton magnetic resonance spectroscopy demonstrates mitochondrial dysfunction in early and advanced Parkinson's disease

(2009) Elke Hattingen et al.   BRAIN

Mitochondrial structural and functional dynamics in Huntington's disease

(2009) P. Hemachandra Reddy et al.   BRAIN RESEARCH REVIEWS

Activation of Ets-2 by oxidative stress induces Bcl-xL expression and accounts for glial survival in amyotrophic lateral sclerosis

(2009) Junghee Lee et al.   FASEB JOURNAL

Stabilization of mitochondrial function by tetramethylpyrazine protects against kainate-induced oxidative lesions in the rat hippocampus

(2009) Shu-Yan Li et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mitochondrial Gene Therapy Augments Mitochondrial Physiology in a Parkinson's Disease Cell Model

(2009) Paula M. Keeney et al.   HUMAN GENE THERAPY

Adipose tissue dysfunction tracks disease progression in two Huntington's disease mouse models

(2009) Jack Phan et al.   HUMAN MOLECULAR GENETICS

Impaired PGC-1α function in muscle in Huntington's disease

(2009) Rajnish K. Chaturvedi et al.   HUMAN MOLECULAR GENETICS

Mitochondrial dynamics-fusion, fission, movement, and mitophagy-in neurodegenerative diseases

(2009) H. Chen et al.   HUMAN MOLECULAR GENETICS

Mutant Pink1 induces mitochondrial dysfunction in a neuronal cell model of Parkinson’s disease by disturbing calcium flux

(2009) Roberta Marongiu et al.   JOURNAL OF NEUROCHEMISTRY

Combination therapy with Coenzyme Q10and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases

(2009) Lichuan Yang et al.   JOURNAL OF NEUROCHEMISTRY

AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity

(2009) Carles Cantó et al.   NATURE

Sustained deficiency of mitochondrial complex I activity during long periods of survival after seizures induced in immature rats by homocysteic acid

(2009) Jaroslava Folbergrová et al.   NEUROCHEMISTRY INTERNATIONAL

Mitochondrial transcription factor A variants and the risk of Parkinson's disease

(2009) Katarzyna Gaweda-Walerych et al.   NEUROSCIENCE LETTERS

AMPK in Health and Disease

(2009) Gregory R. Steinberg et al.   PHYSIOLOGICAL REVIEWS

Silencing of PINK1 Expression Affects Mitochondrial DNA and Oxidative Phosphorylation in DOPAMINERGIC Cells

(2009) Matthew E. Gegg et al.   PLoS One

Mitochondrial bioenergetic deficit precedes Alzheimer's pathology in female mouse model of Alzheimer's disease

(2009) J. Yao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Respiratory-chain diseases related to complex III deficiency

(2008) Paule Bénit et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

A Mitochondrial Protein Compendium Elucidates Complex I Disease Biology

(2008) David J. Pagliarini et al.   CELL

Rosiglitazone Treatment Prevents Mitochondrial Dysfunction in Mutant Huntingtin-expressing Cells

(2008) Rodrigo A. Quintanilla et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nuclear Respiratory Factor 1 Controls Myocyte Enhancer Factor 2A Transcription to Provide a Mechanism for Coordinate Expression of Respiratory Chain Subunits

(2008) Bindu Ramachandran et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Combined R-α-lipoic acid and acetyl-L-carnitine exerts efficient preventative effects in a cellular model of Parkinson’s disease

(2008) Hongyu Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Activation of Peroxisome Proliferator-Activated Receptor Pathway Stimulates the Mitochondrial Respiratory Chain and Can Correct Deficiencies in Patients’ Cells Lacking Its Components

(2008) Jean Bastin et al.   JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

LRRK2 P755L variant in sporadic Parkinson’s disease

(2008) Hiroyuki Tomiyama et al.   JOURNAL OF HUMAN GENETICS

The PPAR trio: Regulators of myocardial energy metabolism in health and disease

(2008) Jose A. Madrazo et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Medication‐induced mitochondrial damage and disease

(2008) John Neustadt et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Towards a transgenic model of Huntington’s disease in a non-human primate

(2008) Shang-Hsun Yang et al.   NATURE

Mitochondrial fragmentation in neurodegeneration

(2008) Andrew B. Knott et al.   NATURE REVIEWS NEUROSCIENCE

Mitochondrial dysfunction: An early event in Alzheimer pathology accumulates with age in AD transgenic mice

(2008) S. Hauptmann et al.   NEUROBIOLOGY OF AGING

Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function

(2008) Richard C. Scarpulla   PHYSIOLOGICAL REVIEWS

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

(2008) W. S. Liang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapidly Increased Neuronal Mitochondrial Biogenesis After Hypoxic-Ischemic Brain Injury

(2008) Wei Yin et al.   STROKE

Peroxisome Proliferator-Activated Receptor-γin Amyotrophic Lateral Sclerosis and Huntington’s Disease

(2008) Mahmoud Kiaei   PPAR Research