Neuroprotective effects of apigenin against inflammation, neuronal excitability and apoptosis in an induced pluripotent stem cell model of Alzheimer’s disease

Common pitfalls of stem cell differentiation: a guide to improving protocols for neurodegenerative disease models and research

(2016) Martin Engel et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Neuroprotection of Neuro2a cells and the cytokine suppressive and anti-inflammatory mode of action of resveratrol in activated RAW264.7 macrophages and C8–B4 microglia

(2016) Nicole Steiner et al.   NEUROCHEMISTRY INTERNATIONAL

Getting to NO Alzheimer’s Disease: Neuroprotection versus Neurotoxicity Mediated by Nitric Oxide

(2016) Rachelle Balez et al.   Oxidative Medicine and Cellular Longevity

Neuronal hyperactivity - A key defect in Alzheimer's disease?

(2015) Marc Aurel Busche et al.   BIOESSAYS

Nitric Oxide Signaling Is Recruited As a Compensatory Mechanism for Sustaining Synaptic Plasticity in Alzheimer's Disease Mice

(2015) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

Dendritic Structural Degeneration Is Functionally Linked to Cellular Hyperexcitability in a Mouse Model of Alzheimer’s Disease

(2014) Zuzana Šišková et al.   NEURON

Flavonoid Apigenin Inhibits Lipopolysaccharide-Induced Inflammatory Response through Multiple Mechanisms in Macrophages

(2014) Xiaoxuan Zhang et al.   PLoS One

The role of polyphenols in the modulation of sirtuins and other pathways involved in Alzheimer's disease

(2013) T. Jayasena et al.   AGEING RESEARCH REVIEWS

Modeling Alzheimer’s Disease with iPSCs Reveals Stress Phenotypes Associated with Intracellular Aβ and Differential Drug Responsiveness

(2013) Takayuki Kondo et al.   Cell Stem Cell

Determination of anti-inflammatory activities of standardised preparations of plant- and mushroom-based foods

(2013) Dhanushka Gunawardena et al.   EUROPEAN JOURNAL OF NUTRITION

Neuroprotective, Anti-Amyloidogenic and Neurotrophic Effects of Apigenin in an Alzheimer’s Disease Mouse Model

(2013) Le Zhao et al.   MOLECULES

Presenilins and  -Secretase: Structure, Function, and Role in Alzheimer Disease

(2013) B. De Strooper et al.   Cold Spring Harbor Perspectives in Medicine

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

Alzheimer's therapeutics: Continued clinical failures question the validity of the amyloid hypothesis—but what lies beyond?

(2012) Kevin Mullane et al.   BIOCHEMICAL PHARMACOLOGY

Induced pluripotent stem cells as tools for disease modelling and drug discovery in Alzheimer’s disease

(2012) Lezanne Ooi et al.   JOURNAL OF NEURAL TRANSMISSION

Cytoprotective properties of traditional Chinese medicinal herbal extracts in hydrogen peroxide challenged human U373 astroglia cells

(2012) Megan L. Steele et al.   NEUROCHEMISTRY INTERNATIONAL

Critical role of soluble amyloid-  for early hippocampal hyperactivity in a mouse model of Alzheimer's disease

(2012) M. A. Busche et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Alzheimer's disease models and functional genomics—How many needles are there in the haystack?

(2012) Jürgen Götz et al.   Frontiers in Physiology

Modeling familial Alzheimer's disease with induced pluripotent stem cells

(2011) Takuya Yagi et al.   HUMAN MOLECULAR GENETICS

Modeling Neurological Disorders by Human Induced Pluripotent Stem Cells

(2011) Tanut Kunkanjanawan et al.   JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY

Human Induced Pluripotent Stem Cells Derived Under Feeder-Free Conditions Display Unique Cell Cycle and DNA Replication Gene Profiles

(2011) Henry C.Y. Chung et al.   STEM CELLS AND DEVELOPMENT

The dysregulation of intracellular calcium in Alzheimer disease

(2010) Charlene Supnet et al.   CELL CALCIUM

Effects of Apigenin on Glutamate-induced [Ca2+]iIncreases in Cultured Rat Hippocampal Neurons

(2010) Ji-Hwa Han et al.   KOREAN JOURNAL OF PHYSIOLOGY & PHARMACOLOGY

Effects of plant-derived polyphenols on TNF-α and nitric oxide production induced by advanced glycation endproducts

(2010) Dave Chandler et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Caspase-3 triggers early synaptic dysfunction in a mouse model of Alzheimer's disease

(2010) Marcello D'Amelio et al.   NATURE NEUROSCIENCE

Generation of microglial cells from mouse embryonic stem cells

(2010) Clara Beutner et al.   Nature Protocols

Apigenin protects HT22 murine hippocampal neuronal cells against endoplasmic reticulum stress-induced apoptosis

(2010) A Young Choi et al.   NEUROCHEMISTRY INTERNATIONAL

Pharmacological shift of the ambiguous nitric oxide action from neurotoxicity to cyclic GMP-mediated protection

(2010) Shigeru Kohgami et al.   NEUROLOGICAL RESEARCH

Nitric Oxide Signaling in Brain Function, Dysfunction, and Dementia

(2010) Joern R. Steinert et al.   NEUROSCIENTIST

Neuronal nitric oxide synthase: Structure, subcellular localization, regulation, and clinical implications

(2009) Li Zhou et al.   NITRIC OXIDE-BIOLOGY AND CHEMISTRY

Calcium dysregulation in Alzheimer's disease: From mechanisms to therapeutic opportunities

(2009) Jin-Tai Yu et al.   PROGRESS IN NEUROBIOLOGY

Apigenin and luteolin modulate microglial activation via inhibition of STAT1-induced CD40 expression

(2008) Kavon Rezai-Zadeh et al.   Journal of Neuroinflammation

Benefits from Dietary Polyphenols for Brain Aging and Alzheimer’s Disease

(2008) L. Rossi et al.   NEUROCHEMICAL RESEARCH

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES